2,090 research outputs found

    Is contact with birth parents beneficial to children in non-kinship foster care? A scoping review of the evidence

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    Many children in non-kinship foster care maintain contact with their birth parents, although debate continues about whether or not, or under what circumstances, it is beneficial to the child. In this scoping review we analyze the findings of studies conducted over the past two decades that have specifically examined face-to-face contact with birth parents for children in non-kinship foster care, our aim being to determine more clearly when it may contribute positively to the child’s well-being. The review was conducted in accordance with PRISMA-ScR guidelines and involved a search of nine electronic databases. A total of 21 studies met the criteria for inclu- sion in the review, namely primary studies analyzing one or more aspects of these contact visits, written in English or Spanish, and published during the period 1997–2022. In analyzing these studies we grouped their findings according to four broad areas of interest: characteristics of contact visits, appraisal of visits by families and professionals, relationship between contact and fostering outcomes, and impact of contact on children. The four main conclusions we draw from the review are: a) surprisingly few studies have specifically examined the effects of face-to-face contact with birth parents in non-kinship foster care; b) the findings to date are neither conclusive nor generalizable, although they are not generally encouraging; c) under the right circumstances (e.g., adequate supervision, conducted in a context of emotional security for the child), contact can contribute to the child’s well-being and increase the likelihood of family reunification; and d) more robust research is needed to guide the development of interventions that can improve parent–child relationships and the quality of contact visitsAndalusian Plan for Research, Development and Innovation (PAIDI) Research Group SEJ-466. Funding for open access charge: Universidad de M ́alaga / CBU

    Filarial worm circulation by mosquitoes along an urbanization gradient in southern Spain

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    Mosquitoes are the main vectors of pathogens affecting wild animals, livestock and humans. Here, we used molecular tools to assess the local circulation of filarial parasites in mosquitoes collected during 2013 from natural, rural and urban habitats from southern Spain. We screened parasites in 22,791 female mosquitoes of the genera Aedes, Culex and Culiseta. Filarial worms were only detected in two mosquito pools. An Ae. caspius pool was positive for Setaria equina and an unidentified worm related to Onchocerca was detected in a Cx. pipiens pool. None of the mosquito pools were positive for Dirofilaria. These results underlay the role of Ae. caspius in the transmission of Setaria parasites among livestock and/or wildlife to humans in southern Spain.Ministerio de Ciencia e Innovació

    Expansion and update version of the SERIES database

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    This document joins deliverables D6.2 "Expansion of the SERIES database" and D6.3 "Updated version of SERIES database" of the SERA project. Maintenance and expansion of the SERIES database is one of the two main objectives of SERA work package 6 "Networking experimental seismic engineering databases (SERIES)". The actions taken to achieve this objective are described in the following and include the creation of the graphical user interface (GUI) and its user manual, the development of tools that assist in the creation of experimental data, and the modifications in the Data Access Portal (DAP) website and back-end. The installation manual and the user manual are given in AnnexesJRC.E.4-Safety and Security of Building

    Review of current SERIES and EPOS Databases

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    In a world-wide scale, collaborations in earthquake engineering lack a common interoperability framework, resulting in tedious and complex procedures to integrate data and results. Up to now, the most significant effort in Europe towards the interoperability of earthquake engineering experimental data was the SERIES project (Seismic Engineering Research Infrastructures for European Synergies) in the period 2009 - 2013. Global sharing of seismological data has been a long-lasting tradition tracing back to the beginning of the previous century. Recently, the ESFRI (European Strategic Forum for Research Infrastructures) initiative and the EPOS project (European Plate Observing System), provided a larger framework for the integration of all solid Earth science data into a single Pan-European e-infrastructure. Up to now, the two adjacent scientific disciplines, i.e. the earthquake engineering and seismology, have not interfaced their data structures, lacking an interoperable data-sharing structure. However, there is need to increase the interaction of the earthquake engineering and seismology communities by integrating the most important databanks and related informatics services in Europe, i.e. SERIES and EPOS. This deliverable presents a review of the current SERIES and EPOS systems: the main features of the two are discussed, focusing on their architecture, content, databases, functionality and access portals. It is noted that aiming to a better knowledge of the EPOS and SERIES projects, the deliverable needed to review also two approaches for data sharing and integration (governance, architecture, collaboration), and not be only limited to a review of current SERIES and EPOS databases. The review presented in the deliverable will serve as the basis for the future roadmap for integration of earthquake engineering and seismological data and informatics services that will support the needs of the two research communities and beyond.JRC.E.4-Safety and Security of Building

    Incorporating Breast Asymmetry Studies into CADx Systems

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    Breast cancer is one of the global leading causes of death among women, and an early detection is of uttermost importance to reduce mortality rates. Screening mammograms, in which radiologists rely only on their eyesight, are one of the most used early detection methods. However, characteristics, such as the asymmetry between breasts, a feature that could be very difficult to visually quantize, is key to breast cancer detection. Due to the highly heterogeneous and deformable structure of the breast itself, incorporating asymmetry measurements into an automated detection system is still a challenge. In this study, we proposed the use of a bilateral registration algorithm as an effective way to automatically measure mirror asymmetry. Furthermore, this information was fed to a machine learning algorithm to improve the accuracy of the model. In this study, 449 subjects (197 with calcifications, 207 with masses, and 45 healthy subjects) from a public database were used to train and evaluate the proposed methodology. Using this procedure, we were able to independently identify subjects with calcifications (accuracy = 0.825, AUC = 0.882) and masses (accuracy = 0.698, AUC = 0.807) from healthy subjects

    Multi-factor authentication model based on multipurpose speech watermarking and online speaker recognition

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    In this paper, a Multi-Factor Authentication (MFA) method is developed by a combination of Personal Identification Number (PIN), One Time Password (OTP), and speaker biometric through the speech watermarks. For this reason, a multipurpose digital speech watermarking applied to embed semi-fragile and robust watermarks simultaneously in the speech signal, respectively to provide tamper detection and proof of ownership. Similarly, the blind semi-fragile speech watermarking technique, Discrete Wavelet Packet Transform (DWPT) and Quantization Index Modulation (QIM) are used to embed the watermark in an angle of the wavelet’s sub-bands where more speaker specific information is available. For copyright protection of the speech, a blind and robust speech watermarking are used by applying DWPT and multiplication. Where less speaker specific information is available the robust watermark is embedded through manipulating the amplitude of the wavelet’s sub-bands. Experimental results on TIMIT, MIT, and MOBIO demonstrate that there is a trade-off among recognition performance of speaker recognition systems, robustness, and capacity which are presented by various triangles. Furthermore, threat model and attack analysis are used to evaluate the feasibility of the developed MFA model. Accordingly, the developed MFA model is able to enhance the security of the systems against spoofing and communication attacks while improving the recognition performance via solving problems and overcoming limitations

    Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease

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    Fibropolycystic liver disease is characterized by hyperproliferation of the biliary epithelium and the formation of multiple dilated cysts, a process associated with unfolded protein response (UPR). In the present study, we aimed to understand the mechanisms of cyst formation and UPR activation in hepatocytic c-Jun N-terminal kinase 1/2 (Jnk1/2) knockout mice. Floxed JNK1/2 (Jnkf/f) and Jnk∆hepa animals were sacrificed at different time points during progression of liver disease. Histological examination of specimens evidenced the presence of collagen fiber deposition, increased α-smooth muscle actin (αSMA), infiltration of CD45, CD11b and F4/80 cells and proinflammatory cytokines (Tnf, Tgfβ1) and liver injury (e.g., ALT, apoptosis and Ki67-positive cells) in Jnk∆hepa compared with Jnkf/f livers from 32 weeks of age. This was associated with activation of effectors of the UPR, including BiP/GRP78, CHOP and spliced XBP1. Tunicamycin (TM) challenge strongly induced ER stress and fibrosis in Jnk∆hepa animals compared with Jnkf/f littermates. Finally, thioacetamide (TAA) administration to Jnk∆hepa mice induced UPR activation, peribiliary fibrosis, liver injury and markers of biliary proliferation and cholangiocarcinoma (CCA). Orthoallografts of DEN/CCl4-treated Jnk∆hepa liver tissue triggered malignant CCA. Altogether, these results suggest that activation of the UPR in conjunction with fibrogenesis might trigger hepatic cystogenesis and early stages of CCA

    QUIJOTE scientific results -- XIII. Intensity and polarization study of supernova remnants in the QUIJOTE-MFI wide survey: CTB 80, Cygnus Loop, HB 21, CTA 1, Tycho and HB 9

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    We use the new QUIJOTE-MFI wide survey (11, 13, 17 and 19 GHz) to produce spectral energy distributions (SEDs), on an angular scale of 1 deg, of the supernova remnants (SNRs) CTB 80, Cygnus Loop, HB 21, CTA 1, Tycho and HB 9. We provide new measurements of the polarized synchrotron radiation in the microwave range. For each SNR, the intensity and polarization SEDs are obtained and modelled by combining QUIJOTE-MFI maps with ancillary data. In intensity, we confirm the curved power law spectra of CTB 80 and HB 21 with a break frequency νb\nu_{\rm b} at 2.00.5+1.2^{+1.2}_{-0.5} GHz and 5.01.0+1.2^{+1.2}_{-1.0} GHz respectively; and spectral indices respectively below and above the spectral break of 0.34±0.04-0.34\pm0.04 and 0.86±0.5-0.86\pm0.5 for CTB 80, and 0.24±0.07-0.24\pm0.07 and 0.60±0.05-0.60\pm0.05 for HB 21. In addition, we provide upper limits on the Anomalous Microwave Emission (AME), suggesting that the AME contribution is negligible towards these remnants. From a simultaneous intensity and polarization fit, we recover synchrotron spectral indices as flat as 0.24-0.24, and the whole sample has a mean and scatter of 0.44±0.12-0.44\pm0.12. The polarization fractions have a mean and scatter of 6.1±1.96.1\pm1.9\%. When combining our results with the measurements from other QUIJOTE studies of SNRs, we find that radio spectral indices are flatter for mature SNRs, and particularly flatter for CTB 80 (0.240.06+0.07-0.24^{+0.07}_{-0.06}) and HB 21 (0.340.03+0.04-0.34^{+0.04}_{-0.03}). In addition, the evolution of the spectral indices against the SNRs age is modelled with a power-law function, providing an exponent 0.07±0.03-0.07\pm0.03 and amplitude 0.49±0.02-0.49\pm0.02 (normalised at 10 kyr), which are conservative with respect to previous studies of our Galaxy and the Large Magellanic Cloud.Comment: 33 pages, 15 figure, 15 tables. Submitted to MNRAS. QUIJOTE data maps available at https://research.iac.es/proyecto/quijot

    Integrative development of a short screening questionnaire of highly processed food consumption (sQ-HPF)

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    Background: Recent lifestyle changes include increased consumption of highly processed foods (HPF), which has been associated with an increased risk of non-communicable diseases (NCDs). However, nutritional information relies on the estimation of HPF consumption from food-frequency questionnaires (FFQ) that are not explicitly developed for this purpose. We aimed to develop a short screening questionnaire of HPF consumption (sQ-HPF) that integrates criteria from the existing food classification systems. Methods: Data from 4400 participants (48.1% female and 51.9% male, 64.9 +/- 4.9 years) of the Spanish PREDIMED-Plus (PREvention with MEDiterranean DIet) trial were used for this analysis. Items from the FFQ were classified according to four main food processing-based classification systems (NOVA, IARC, IFIC and UNC). Participants were classified into tertiles of HPF consumption according to each system. Using binomial logistic regression, food groups associated with agreement in the highest tertile for at least two classification systems were chosen as items for the questionnaire. ROC analysis was used to determine cut-off points for the frequency of consumption of each item, from which a score was calculated. Internal consistency of the questionnaire was assessed through exploratory factor analysis (EFA) and Cronbach's analysis, and agreement with the four classifications was assessed with weighted kappa coefficients. Results: Regression analysis identified 14 food groups (items) associated with high HPF consumption for at least two classification systems. EFA showed that items were representative contributors of a single underlying factor, the HPF dietary pattern (factor loadings around 0.2). We constructed a questionnaire asking about the frequency of consumption of those items. The threshold frequency of consumption was selected using ROC analysis. Comparison of the four classification systems and the sQ-HPF showed a fair to high agreement. Significant changes in lifestyle characteristics were detected across tertiles of the sQ-HPF score. Longitudinal changes in HPF consumption were also detected by the sQ-HPF, concordantly with existing classification systems. Conclusions: We developed a practical tool to measure HPF consumption, the sQ-HPF. This may be a valuable instrument to study its relationship with NCDs
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