Emotional Memory: Examining Differences in Retrieval Methods

Emotional information is generally remembered better than non-emotional information, especially when the emotional information is highly arousing. Priority Binding Theory has grown out of several years worth of research on memory and emotion. The theory proposes that in mixed lists comprised of negative and arousing words and neutral words, negative and arousing words will take priority during mental processing resulting in stronger encoding for the emotional words relative to neutral words with no such effect predicted for pure lists. Our lab made several attempts to extend the theory to picture stimuli, but were unsuccessful. However, the predictions of Priority Binding Theory were tested using recall, while studies in our lab have used recognition as a retrieval method. Research suggests that retrieval processes may be distinct and affected differently by various factors. Therefore, the current study manipulated retrieval methods, recognition and recall, to determine if the predictions of Priority Binding Theory were retrieval dependent. Results showed an overall increase in accuracy for negative images versus neutral images. The degree of accuracy for negative versus neutral images differed by retrieval method, with the difference between accuracy for negative versus neutral information greater in recall formats. In terms of retrieval method, recognition accuracy showed ceiling effects and no effect of list type was observed, but in recall significant differences were observed between negative and neutral stimuli in mixed lists and no significant differences observed between pure negative and pure neutral lists. The present results supports the predictions of Priority Binding Theory

Emotional Memory: The Effects of Temporal Pressure on Episodic Memory

Priority Binding theory (MacKay et al., 2004) proposes that under temporal pressure arousing negative stimuli delay binding of neutral items presented in close temporal proximity (as in lists with mixed neutral and negative stimuli). With fast presentation rates, a subsequent negative item may interrupt the binding process for the preceding neutral stimulus. This results in more accurate memory for negative images presented in mixed lists. However, in slow presentation rates, binding occurs equally for all items. Therefor, no such advantage is predicted comparing images presented in lists of the same valence. This study examined the predictions of priority binding theory by manipulating temporal pressure across lists of emotional visual images. Results showed performance difference between rates, with better accuracy, sensitivity, a greater bias at the slow rate, and a trend for better accuracy for negative images than neutral images in mixed lists, which supports the predictions of binding theory. The results extend the predictions of priority binding theory to picture stimuli. However, more research need to be conducted to determine if image stimuli are differentially processed and remembered than word stimuli

Étude histologique de la maladie parodontale canine traitée par greffe d’ASC autologues : validation d’un protocole de décalcification des dents

La maladie parodontale a une prévalence très importante en médecine vétérinaire comme en médecine humaine. Malgré sa fréquence, les traitements actuels donnent des résultats de régénération parodontale décevants et une hétérogénéité importante en fonction des patients. Le but de l’étude dans laquelle s’inscrit cette thèse est d’observer l’histologie du parodonte après différents traitements et notamment un innovant à base d’ASC autologues. Pour ce faire, il nous a fallu déterminer un protocole de décalcification des dents efficace et reproductible. Celui ayant donné le meilleur compromis temps de décalcification/qualité histologique est l’acide chlorhydrique 10-20% en solution commerciale (Décalc®). C’est donc ce protocole qui sera utilisé pour décalcifier les dents des derniers chiens de l’étude afin de déterminer l’intérêt de la greffe d’ASC autologues dans la régénération du parodonte lors de maladie parodontale canine

Cu(0), O2 and mechanical forces: a saving combination for efficient production of Cu-NHC complexes

International audienc

A more sustainable and efficient access to IMes·HCl and IPr·HCl by ball-milling

International audienc

Amaranth (Amaranthus hypochondriacus) Vicilin Subunit Structure

The 7S-globulin fraction is a minor component of the amaranth storage proteins. The present work provides new information about this protein. The amaranth 7S-globulin or vicilin presented a sedimentation coefficient of 8.6 ± 0.6 S and was composed of main subunits of 66, 52, 38, and 16 kDa. On the basis of mass spectrometry (MS) analysis of tryptic fragments, the 52, 38, and 16 kDa subunits presented sequence homology with sesame vicilin, whereas the 66 kDa subunit showed sequence similarity with a putative vicilin. Several characteristics of the 66 kDa subunit were similar to members of the convicilin family. Results support the hypothesis that the 7S-globulin molecules are composed of subunits coming from at least two gene families with primary products of 66 and 52 kDa, respectively. According to the present information, amaranth vicilin may be classified into the vicilin group that includes pea, broad bean, and sesame vicilins, among others.Fil: Quiroga, Alejandra Viviana. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Martinez, Estela Nora. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Rogniaux, Hélène. Instituto National de Recherches Agronomiques. Biopolymères Interactions Assemblages; FranciaFil: Geairon, Audrey. Instituto National de Recherches Agronomiques. Biopolymères Interactions Assemblages; FranciaFil: Añon, Maria Cristina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentin

A coiled-coil affinity-based system for the controlled release of biofunctionalized gold nanoparticles from alginate hydrogels

Affinity-based systems represent a promising solution to control the delivery of therapeutics using hydrogels. Here, we report a hybrid system that is based on the peptidic E/K coiled coil affinity pair to mediate the release of gold nanoparticles (NPs) from alginate scaffolds. On one hand, the gold NPs were functionalized with the Ecoil-tagged epidermal growth factor (EGF). The bioactivity of the grafted EGF and the bioavailability of the Ecoil moiety were confirmed by EGF receptor phosphorylation assays and by capturing the functionalized NPs on a Kcoil-derivatized surface. On the other hand, alginate chains were modified with azido-homoalanine Kcoil (Aha-Kcoil) by azide–alkyne click chemistry. The hybrid system was formed by dispersing NPs functionalized with the Ecoil-tagged EGF in alginate hydrogels containing either 0, 10, or 20% of Kcoil-modified alginate (Alg-Kcoil). With 20% of Alg-Kcoil, the release of Ecoil-functionalized NPs was reduced by half when compared to the release of NPs without Ecoil, whereas little to no differences were noticed with either 0 or 10% of Alg-Kcoil. Differential dynamic microscopy was used to determine the diffusion coefficient of the NPs, and the results showed a decrease in the diffusion coefficient of Ecoil-functionalized NPs, when compared to bare PEGylated NPs. Altogether, our data demonstrated that the E/K coiled coil system can control the release of NPs in a high Kcoil content alginate gel, opening diverse applications in drug delivery

Learning from the past : Impact of the Arctic Oscillation on sea ice and marine productivity off northwest Greenland over the last 9,000 years

Climate warming is rapidly reshaping the Arctic cryosphere and ocean conditions, with consequences for sea ice and pelagic productivity patterns affecting the entire marine food web. To predict how ongoing changes will impact Arctic marine ecosystems, concerted effort from various disciplines is required. Here, we contribute multi-decadal reconstructions of changes in diatom production and sea-ice conditions in relation to Holocene climate and ocean conditions off northwest Greenland. Our multiproxy study includes diatoms, sea-ice biomarkers (IP(25)and HBI III) and geochemical tracers (TOC [total organic carbon], TOC:TN [total nitrogen], delta C-13, delta N-15) from a sediment core record spanning the last c. 9,000 years. Our results suggest that the balance between the outflow of polar water from the Arctic, and input of Atlantic water from the Irminger Current into the West Greenland Current is a key factor in controlling sea-ice conditions, and both diatom phenology and production in northeastern Baffin Bay. Our proxy record notably shows that changes in sea-surface conditions initially forced by Neoglacial cooling were dynamically amplified by the shift in the dominant phase of the Arctic Oscillation (AO) mode that occurred at c. 3,000 yr BP, and caused drastic changes in community composition and a decline in diatom production at the study site. In the future, with projected dominant-positive AO conditions favored by Arctic warming, increased water column stratification may counteract the positive effect of a longer open-water growth season and negatively impact diatom production.Peer reviewe