174 research outputs found
Analysis of Set-theoretic and Stochastic Models for Fusion under Unknown Correlations
In data fusion theory, multiple estimates are combined to yield an optimal result. In this paper, the set of all possible results is investigated, when two random variables with unknown correlations are fused. As a first step, recursive processing of the set of estimates is examined. Besides set-theoretic considerations, the lack of knowledge about the unknown correlation coefficient is modeled as a stochastic quantity. Especially, a uniform model is analyzed, which provides a new optimization criterion for the covariance intersection algorithm in scalar state spaces. This approach is also generalized to multi-dimensional state spaces in an approximative, but fast and scalable way, so that consistent estimates are obtained
Geothermienutzung in sÀchsischen Gartenbaubetrieben
Die BroschĂŒre beschreibt Möglichkeiten der WĂ€rmeversorgung von sĂ€chsischen Gartenbaubetrieben mit Geothermie in AbhĂ€ngigkeit von geologischen Standortfaktoren und Betriebsstrukturen/ Nutzungskonzepten.
Ziel des Projektes war, fĂŒr die Beheizung von GewĂ€chshĂ€usern den Einsatz von Geothermie zur Grundlastversorgung zu untersuchen. Hervorzuheben ist hierbei die VerknĂŒpfung der geologischen/geothermisch und gĂ€rtnereitechnischen Komponente. Die Ergebnisse zeigen, welches geothermische System die wirtschaftlichste Variante fĂŒr GewĂ€chshĂ€user und deren Nutzung ist.
Das Projekt stellt eine Entscheidungsgrundlage fĂŒr die Nutzung von Geothermie in sĂ€chsischen Gartenbaubetrieben dar
Vp/Vs ratios in the ParnaĂba Basin from joint active-passive seismic analysis â Implications for continental amalgamation and basin formation
Acknowledgements The authors thank Jordi JuliĂ and two anonymous reviewers for valuable comments on an earlier version of the manuscript. Thanks to the PBAP program for the availability of WARR, DSR and teleseismic three-component data (Project 5547: BP ENERGY/FUB/FINATECâ PARNAĂBA BASIN REFRACTION EXPERIMENT). RAF thanks CNPq and INCT Estudos TectĂŽnicos (CNPq, CAPES, FAP-DF) for research fellowship and funds. *The data that support the findings of this study may be available from the authors upon reasonable request.Peer reviewedPublisher PD
Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport
Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achieved remains unclear. Here we show that in Arabidopsis thaliana, auxin patterning and cellular growth are linked through a correlated pattern of auxin efflux carrier localization and cortical microtubule orientation. Our experiments reveal that both PIN1 localization and microtubule array orientation are likely to respond to a shared upstream regulator that appears to be biomechanical in nature. Lastly, through mathematical modeling we show that such a biophysical coupling could mediate the feedback loop between auxin and its transport that underlies plant phyllotaxis
Modal Ω-Logic: Automata, Neo-Logicism, and Set-Theoretic Realism
This essay examines the philosophical significance of -logic in Zermelo-Fraenkel set theory with choice (ZFC). The duality between coalgebra and algebra permits Boolean-valued algebraic models of ZFC to be interpreted as coalgebras. The modal profile of -logical validity can then be countenanced within a coalgebraic logic, and -logical validity can be defined via deterministic automata. I argue that the philosophical significance of the foregoing is two-fold. First, because the epistemic and modal profiles of -logical validity correspond to those of second-order logical consequence, -logical validity is genuinely logical, and thus vindicates a neo-logicist conception of mathematical truth in the set-theoretic multiverse. Second, the foregoing provides a modal-computational account of the interpretation of mathematical vocabulary, adducing in favor of a realist conception of the cumulative hierarchy of sets
A de novo assembly of the newt transcriptome combined with proteomic validation identifies new protein families expressed during tissue regeneration
Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus.
BACKGROUND: Alternative therapies for Staphylococcus aureus bacteremia and endocarditis are needed.
METHODS: We randomly assigned 124 patients with S. aureus bacteremia with or without endocarditis to receive 6 mg of daptomycin intravenously per kilogram of body weight daily and 122 to receive initial low-dose gentamicin plus either an antistaphylococcal penicillin or vancomycin. The primary efficacy end point was treatment success 42 days after the end of therapy.
RESULTS: Forty-two days after the end of therapy in the modified intention-to-treat analysis, a successful outcome was documented for 53 of 120 patients who received daptomycin as compared with 48 of 115 patients who received standard therapy (44.2 percent vs. 41.7 percent; absolute difference, 2.4 percent; 95 percent confidence interval, -10.2 to 15.1 percent). Our results met prespecified criteria for the noninferiority of daptomycin. The success rates were similar in subgroups of patients with complicated bacteremia, right-sided endocarditis, and methicillin-resistant S. aureus. Daptomycin therapy was associated with a higher rate of microbiologic failure than was standard therapy (19 vs. 11 patients, P=0.17). In 6 of the 19 patients with microbiologic failure in the daptomycin group, isolates with reduced susceptibility to daptomycin emerged; similarly, a reduced susceptibility to vancomycin was noted in isolates from patients treated with vancomycin. As compared with daptomycin therapy, standard therapy was associated with a nonsignificantly higher rate of adverse events that led to treatment failure due to the discontinuation of therapy (17 vs. 8, P=0.06). Clinically significant renal dysfunction occurred in 11.0 percent of patients who received daptomycin and in 26.3 percent of patients who received standard therapy (P=0.004).
CONCLUSIONS: Daptomycin (6 mg per kilogram daily) is not inferior to standard therapy for S. aureus bacteremia and right-sided endocarditis. (ClinicalTrials.gov number, NCT00093067 [ClinicalTrials.gov].)
Der Geologische Dienst in Sachsen: Festband zum JubilÀum 150 Jahre Landesgeologie
Der Geologische Dienst von Sachsen feiert im Jahr 2022 sein 150-jĂ€hriges JubilĂ€um â am 6. April 1872 wurde die Geologische Landesuntersuchung im Königreich Sachsen gegrĂŒndet. Auf 153 Seiten der Reihe âGeoprofilâ werden Einblicke in die Arbeit des Geologischen Dienstes im LfULG, seinen Aufgaben und die Dienste als zustĂ€ndige Fachbehörde gegeben. Die elf EinzelbeitrĂ€ge zeigen die aktuellen Herausforderungen und Chancen, die sich aus den Themenbereichen Umwelt, Naturschutz und Geologie fĂŒr Sachsen stellen. Im Einzelnen geht es in den BeitrĂ€gen um die sĂ€chsische Rohstoffstrategie, die Suche nach einem Endlagerstandort fĂŒr radioaktive AbfĂ€lle, ErdwĂ€rme, Hydrogeologie, die Eisenbahn Neubaustrecke Dresden â Prag, Naturgefahren, das geowissenschaftliche Archiv, TrĂ€ger öffentlicher Belange (TöB), Geoparks und einen Blick in die 150 jĂ€hrige Geschichte.
Redaktionsschluss: 30.11.202
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