Caso Clínico ARP Nº 3: Não Compactação Ventricular e Enfarte do Ventrículo Esquerdo

Paciente do sexo masculino, de 45 anos de idade, com antecedentes de patologia cardíaca e alterações em ecocardiograma para estudo.São apresentadas quatro imagens, uma “steady-state-freeprecession”no plano 4 câmaras e três imagens de realce tardio, no eixo curto, 4 câmaras e eixo longo vertical.Na imagem 1 (“steady-state-free-precession” no plano 4 câmaras ou eixo longo horizontal em diástole) observa-se acentuação da trabeculação nos segmentos médio-apicais da parede lateral e do ápex (segmento 17) do ventrículo esquerdo, com razão entre a camada não compactada superior a 2,3. Identifica-se ainda acentuação da trabeculação na parede livre do ventrículo direito.Nas imagens de realce tardio identifica-se realce tardio transmural nos segmentos médios anterior, antero-lateral e antero-septal, apicais anterior e inferior e ápex.Estes achados são compatíveis com não compactação ventricular e enfarte do ventrículo esquerdo

Editorial

This being my first editorial after March elections, I think it is important to share and reflect on the main guidelines that will conduct the action of the new Management. First of all, a word of appreciation to all previous Directorates for their work in favor of the Portuguese Radiology, gradually increasing its external visibility and always maintaining a particular emphasis on the continuous training of Radiologists. Migrating contents to online platforms is a worldwide trend that we will have to follow. The Society has on file a large source of papers presented at high quality Congresses and Meetings, which will be available in the Members area for consultation. The Radiological Act will maintain its important role as a vehicle for the dissemination of the national scientific production and its indexation is in progress. The Society School has played a key role in the training of residents and it will be maintained. Given its great success we will seek to broaden its scope to allow Experts to take advantage of this as well. We will maintain the organization of all the usual Courses and Congresses, as well as the existing partnerships with similar Scientific Societies. Training residents will also be fundamental in our line of action. The Portuguese Society of Radiology and Nuclear Medicine, despite being a society of a scientific nature, cannot ignore the “non-scientific” problems that affect Radiologists, namely in terms of their professional practice and will continue to support and organize discussion forums where these issues can be debated and discussed. To achieve these goals we need everyone's collaboration! Please send suggestions and/or criticism to the Society on how we can improve our action. At a time when our specialty is the target of multiple attacks from many different directions, we will only be able to prevail if we remain united and focused on our goals.Sendo este o meu primeiro editorial após as eleições de Março passado acho importante partilhar e refletir sobre as principais linhas mestras que irão balizar a ação da nova Direção. Mas antes uma palavra de apreço a todas as Direções anteriores pelo seu trabalho em prol da Radiologia Portuguesa, aumentando de modo gradual a sua visibilidade externa e mantendo sempre uma particular ênfase na formação contínua dos Radiologistas. A migração de conteúdos para plataformas online é uma tendência mundial que teremos de acompanhar. A Sociedade dispõe em arquivo de um grande manancial de trabalhos apresentados nos Congressos e Reuniões de elevada qualidade e que irá disponibilizar na área reservada aos Sócios para consulta. A Acta Radiológica irá manter o seu importante papel como veículo de disseminação da produção científica nacional e está em curso a sua indexação. A Escola da Sociedade tem tido um papel fundamental na formação dos Internos e irá ser mantida. Dado o seu grande sucesso procuraremos alargar o seu âmbito de modo a permitir aos Especialistas que também possam usufruir dela. Iremos manter a organização de todos os Cursos e Congressos habituais, bem como as parcerias vigentes com as Sociedades Científicas congéneres. A formação dos Internos também será um ponto fundamental da nossa ação. A Sociedade Portuguesa de Radiologia e Medicina Nuclear, apesar de ser uma sociedade de índole científica não se pode alhear dos problemas “não científicos” que afetam os Radiologistas, nomeadamente a nível do seu exercício profissional pelo que continuará a apoiar e organizar fóruns de discussão em que esses assuntos possam ser debatidos e discutidos. Para conseguirmos alcançar estes objetivos precisamos da colaboração de todos! Façam por favor chegar sugestões e / ou críticas à Sociedade acerca do modo como poderemos melhorar a nossa ação. Nesta altura em que a nossa Especialidade é alvo de múltiplos ataques das mais variadas direções apenas conseguiremos prevalecer se nos mantivermos unidos e focados nos nossos objetivos

Caso Clínico ARP Nº3: Qual o seu Diagnóstico?

Paciente do sexo masculino, com 45 anos de idade, com antecedentes de patologia cardíaca e alterações em ecocardiograma para estudo.Pedido R

African Histoplasmosis

African histoplasmosis (AH) is a fungal infection due to Histoplasma capsulatum var. duboisii. Unlike classic histoplasmosis, infections caused by H. duboisii most commonly affects the skin, subcutaneous tissues, lymph nodes and bones. Till present, in Europe, all published cases have been from natives from Africa who moved to Europe. There are few reports in the literature describing the radiologic features of AH.The authors report a case of a 7-year-old girl, from Guine-Bissau, who had multiple skin and subcutaneous lesions and left lower limb deformity. The presence of H. duboisii was confirmed by culture and histologic examination. Imaging studies were performed and showed multiple calcified and non-calcified subcutaneous lesions compatible with granulomas/abscesses; axillary and thoracic lymphadenopathies; and signs of chronic osteomyelitis. Although these imaging features are not pathognomic they should raise awareness for the diagnosis of AH in patients that are African or people who have travelled from this continent. Imaging plays a crucial role not only in the diagnosis of this disease but also in monitoring the response to therapy and detecting recurrence

Integrated monitoring of mola mola behaviour in space and time

Over the last decade, ocean sunfish movements have been monitored worldwide using various satellite tracking methods. This study reports the near-real time monitoring of finescale (< 10 m) behaviour of sunfish. The study was conducted in southern Portugal in May 2014 and involved satellite tags and underwater and surface robotic vehicles to measure both the movements and the contextual environment of the fish. A total of four individuals were tracked using custom-made GPS satellite tags providing geolocation estimates of fine-scale resolution. These accurate positions further informed sunfish areas of restricted search (ARS), which were directly correlated to steep thermal frontal zones. Simultaneously, and for two different occasions, an Autonomous Underwater Vehicle (AUV) videorecorded the path of the tracked fish and detected buoyant particles in the water column. Importantly, the densities of these particles were also directly correlated to steep thermal gradients. Thus, both sunfish foraging behaviour (ARS) and possibly prey densities, were found to be influenced by analogous environmental conditions. In addition, the dynamic structure of the water transited by the tracked individuals was described by a Lagrangian modelling approach. The model informed the distribution of zooplankton in the region, both horizontally and in the water column, and the resultant simulated densities positively correlated with sunfish ARS behaviour estimator (r(s) = 0.184, p < 0.001). The model also revealed that tracked fish opportunistically displace with respect to subsurface current flow. Thus, we show how physical forcing and current structure provide a rationale for a predator's finescale behaviour observed over a two weeks in May 2014

Design of bio-nanosystems for oral delivery of functional compounds

Nanotechnology has been referred to as one of the most interesting topics in food technology due to the potentialities of its use by food industry. This calls for studying the behavior of nanosystems as carriers of biological and functional compounds aiming at their utilization for delivery, controlled release and protection of such compounds during food processing and oral ingestion. This review highlights the principles of design and production of bio-nanosystems for oral delivery and their behavior within the human gastrointestinal (GI) tract, while providing an insight into the application of reverse engineering approach to the design of those bio-nanosystems. Nanocapsules, nanohydrogels, lipid-based and multilayer nanosystems are discussed (in terms of their main ingredients, production techniques, predominant forces and properties) and some examples of possible food applications are given. Phenomena occurring in in vitro digestion models are presented, mainly using examples related to the utilization of lipid-based nanosystems and their physicochemical behavior throughout the GI tract. Furthermore, it is shown how a reverse engineering approach, through two main steps, can be used to design bio-nanosystems for food applications, and finally a last section is presented to discuss future trends and consumer perception on food nanotechnology.Miguel A. Cerqueira, Ana C. Pinheiro, Helder D. Silva, Philippe E. Ramos, Ana I. Bourbon, Oscar L. Ramos (SFRH/BPD/72753/2010, SFRH/BD/48120/2008, SFRH/BD/81288/2011, SFRH/BD/80800/2011, SFRH/BD/73178/2010 and SFRH/BPD/80766/2011, respectively) are the recipients of a fellowship from the Fundacao para a Ciencia e Tecnologia (FCT, POPH-QREN and FSE Portugal). Maria L. Flores-Lopez thanks Mexican Science and Technology Council (CONACYT, Mexico) for PhD fellowship support (CONACYT Grant number: 215499/310847). The support of EU Cost Actions FA0904 and FA1001 is gratefully acknowledged

Colegio Radiologia

Neste espaço de divulgação do Colégio de Especialidade da Ordem dos Médicos gostava hoje de abordar um tema sobre o qual somos muitas vezes questionados e sobre o qual ainda há muitas ideias e conceitos errados, nomeadamente as não conformidades com a legislação.O Colégio de Especialidade, como “órgão técnico consultivo da Ordem dos Médicos” (artº 3º do Regulamento Geral dos Colégios das Especialidades), não tem autonomia para desencadear ações de fiscalização ou para investigar eventuais denúncias de ilegalidades cometidas no âmbito da Radiologia

Kaposiform hemangioendothelioma of the thigh: A case report

Kaposiform hemangioendothelioma is a rare, locally aggressive or borderline vascular tumor that typically affects infants. It presents as a purpuric cutaneous lesion and may be associated with life-threatening coagulation disorders, such as the Kasabach-Merritt phenomenon. The differential diagnosis can be challenging based on clinical presentation alone. Imaging plays a crucial role in the diagnostic workup, particularly magnetic resonance imaging.We present a case report of a 4-month-old patient with an enlarging vinous cutaneous mass on the thigh and coagulation abnormalities. Magnetic resonance imaging revealed a large, infiltrative, soft-tissue lesion with poorly defined margins and heterogeneous enhancement, that involved all muscle compartments of the thigh and was associated with lymphedema, stranding of the subcutaneous fat and cutaneous thickening. These findings were consistent with kaposiform hemangioendothelioma of the thigh and the diagnosis was confirmed by histopathological characterization

Sharing Biomedical Data: Strengthening AI Development in Healthcare.

Artificial intelligence (AI)-based solutions have revolutionized our world, using extensive datasets and computational resources to create automatic tools for complex tasks that, until now, have been performed by humans. Massive data is a fundamental aspect of the most powerful AI-based algorithms. However, for AI-based healthcare solutions, there are several socioeconomic, technical/infrastructural, and most importantly, legal restrictions, which limit the large collection and access of biomedical data, especially medical imaging. To overcome this important limitation, several alternative solutions have been suggested, including transfer learning approaches, generation of artificial data, adoption of blockchain technology, and creation of an infrastructure composed of anonymous and abstract data. However, none of these strategies is currently able to completely solve this challenge. The need to build large datasets that can be used to develop healthcare solutions deserves special attention from the scientific community, clinicians, all the healthcare players, engineers, ethicists, legislators, and society in general. This paper offers an overview of the data limitation in medical predictive models; its impact on the development of healthcare solutions; benefits and barriers of sharing data; and finally, suggests future directions to overcome data limitations in the medical field and enable AI to enhance healthcare. This perspective is dedicated to the technical requirements of the learning models, and it explains the limitation that comes from poor and small datasets in the medical domain and the technical options that try or can solve the problem related to the lack of massive healthcare data