Innovation processes and industrial districts

In this survey, we examine the operations of innovation processes within industrial districts by exploring the ways in which differentiation, specialization, and integration affect the generation, diffusion, and use of new knowledge in such districts. We begin with an analysis of the importance of the division of labour and then investigate the effects of social embeddedness on innovation. We also consider the effect of forms of organization within industrial districts at various stages of product and process life, and we examine the negative aspects of embeddedness for innovation. We conclude with a discussion of the possible consequences of new information and communications technologies on innovation in industrial districts

Analysis of Carbon/Carbon Fragments From the Columbia Tragedy

The extensive investigation following the Space Shuttle Orbiter Columbia accident of February 1, 2003 determined that hot gases entered the wing through a breach in the protective reinforced carbon/carbon (RCC) leading edge. In the current study, the exposed edges of the recovered RCC from the vicinity of the breach are examined with scanning electron microscopy and Raman spectroscopy. Electron microscopy of the exposed edges revealed regions of pointed carbon fibers, characteristic of exposure to high temperature oxidizing gases. The Raman technique relates the observed 1350 and 1580 to 1600 cm(-1) bands to graphitic dom ains and their corresponding temperatures of formation. Some of the regions showed evidence of exposure temperatures beyond 2700 ?C during the accident

IHPRPT Steering Committee Meeting - NASA Spacecraft Propulsion Update

The activities and status of NASA Spacecraft Propulsion is presented including recent accomplishments

Quantifying the response of Blainville’s beaked whales to U.S. naval sonar exercises in Hawaii

Funding: US Navy Living Marine Resources Program (Grant Number(s): N39430-17-P-1983).Behavioral responses of beaked whales (family Ziphiidae) to naval use of mid-frequency active sonar (MFAS) have been quantified for some species and regions. We describe the effects of MFAS on the probability of detecting diving groups of Blainville's beaked whales on the U.S. Navy Pacific Missile Range Facility (PMRF) in Hawaii and compare our results to previously published results for the same species at the Atlantic Undersea Test and Evaluation Center (AUTEC) in the Bahamas. We use passive acoustic data collected at bottom-mounted hydrophones before and during six naval training exercises at PMRF along with modelled sonar received levels to describe the effect of training and MFAS on foraging groups of Blainville's beaked whales. We use a multistage generalized additive modeling approach to control for the underlying spatial distribution of vocalizations under baseline conditions. At an MFAS received level of 150 dB re 1 μPa rms the probability of detecting groups of Blainville's beaked whales decreases by 77%, 95% CI [67%, 84%] compared to periods when general training activity was ongoing and by 87%, 95% CI [81%, 91%] compared to baseline conditions. Our results indicate a more pronounced response to naval training and MFAS than has been previously reported.Publisher PDFPeer reviewe

Receptor-independent metabolism of platelet-activating factor by myelogenous cells

AbstractHuman neutrophils incorporate and metabolize platelet-activating factor (PAF). We dissociated these events from PAF binding to its receptors. Cells were pretreated with either pronase, a PAF antagonist (L652731), or excess PAF. This reduced PAF receptor numbers by 70 to almost 100% but had no comparable effect upon the neutrophil's ability to metabolize PAF. Furthermore, HL-60 cells efficiently metabolized, but did not specifically bind, PAF. Thus, PAF receptor availability did not correlate with PAF metabolic capacity and we conclude that myelogenous tissues can process this bioactive ligand by a receptor-independent pathway

Book Reviews

Reviews of the following books: Island in Time: A Natural and Human History of the Islands of Maine by Philip W. Conkling; A Seafaring Legacy: The Photographs, Diaries and Memorabilia of a Maine Sea Captain and His Wife by Julianna FreeHand; Coming of Age on Damariscove Island, Maine by Carl R. Griffin III and Alaric Faulkner; The Identity of the St. Francis Indians by Gordon M. Day; Soldiers, Sailors and Patriots of the Revolutionary War: Maine by Carleton E. Fisher and Sue K. Fisher

Unitarity and the Hilbert space of quantum gravity

Under the premises that physics is unitary and black hole evaporation is complete (no remnants, no topology change), there must exist a one-to-one correspondence between states on future null and timelike infinity and on any earlier spacelike Cauchy surface (e.g., slices preceding the formation of the hole). We show that these requirements exclude a large set of semiclassical spacetime configurations from the Hilbert space of quantum gravity. In particular, the highest entropy configurations, which account for almost all of the volume of semiclassical phase space, would not have quantum counterparts, i.e. would not correspond to allowed states in a quantum theory of gravity.Comment: 7 pages, 3 figures, revtex; minor changes in v2 (version published in Class. Quant. Grav.

Linear constraints from generally covariant systems with quadratic constraints

How to make compatible both boundary and gauge conditions for generally covariant theories using the gauge symmetry generated by first class constraints is studied. This approach employs finite gauge transformations in contrast with previous works which use infinitesimal ones. Two kinds of variational principles are taken into account; the first one features non-gauge-invariant actions whereas the second includes fully gauge-invariant actions. Furthermore, it is shown that it is possible to rewrite fully gauge-invariant actions featuring first class constraints quadratic in the momenta into first class constraints linear in the momenta (and homogeneous in some cases) due to the full gauge invariance of their actions. This shows that the gauge symmetry present in generally covariant theories having first class constraints quadratic in the momenta is not of a different kind with respect to the one of theories with first class constraints linear in the momenta if fully gauge-invariant actions are taken into account for the former theories. These ideas are implemented for the parametrized relativistic free particle, parametrized harmonic oscillator, and the SL(2,R) model.Comment: Latex file, revtex4, 18 pages, no figures. This version includes the corrections to many misprints of v1 and also the ones of the published version. The conceptual and technical parts of the paper are not altere