652 research outputs found
Resonant and anti-resonant frequency dependence of the effective parameters of metamaterials
We present a numerical study of the electromagnetic response of the
metamaterial elements that are usedto construct materials with negative
refractive index. For an array of split ring resonators (SRR) we find that the
resonant behavior of the effective magnetic permeability is accompanied by an
anti-resonant behavior of the effective permittivity. In addition, the
imaginary parts of the effective permittivity and permeability are opposite in
sign. We also observe an identical resonant versus anti-resonant frequency
dependence of the effective materials parameters for a periodic array of thin
metallic wires with cuts placed periodically along the length of the wire, with
roles of the permittivity and permeability reversed from the SRR case. We show
in a simple manner that the finite unit cell size is responsible for the
anti-resonant behavior
Electromagnetic-field quantization and spontaneous decay in left-handed media
We present a quantization scheme for the electromagnetic field interacting
with atomic systems in the presence of dispersing and absorbing
magnetodielectric media, including left-handed material having negative real
part of the refractive index. The theory is applied to the spontaneous decay of
a two-level atom at the center of a spherical free-space cavity surrounded by
magnetodielectric matter of overlapping band-gap zones. Results for both big
and small cavities are presented, and the problem of local-field corrections
within the real-cavity model is addressed.Comment: 15 pages, 5 figures, RevTe
Source and purity of dengue-viral preparations impact requirement for enhancing antibody to induce elevated IL-1β secretion: A primary human monocyte model
Dengue virus is a major global health threat and can lead to life-threatening hemorrhagic complications due to immune activation and cytokine production. Cross-reactive antibodies to an earlier dengue virus infection are a recognized risk factor for severe disease. These antibodies bind heterologous dengue serotypes and enhance infection into Fc-receptorbearing cells, a process known as antibody-dependent enhancement of infection. One crucial cytokine seen elevated in severe dengue patients is IL-1β, a potent inflammatory cytokine matured by the inflammasome. We used a highly-physiologic system by studying antibody-dependent enhancement of IL-1β in primary human monocytes with anti-dengue human monoclonal antibodies isolated from patients. Antibody-enhancement increased viral replication in primary human monocytes inoculated with supernatant harvested from Vero cells infected with dengue virus serotype 2 (DENV-2) 16681. Surprisingly, IL-1β secretion induced by infectious supernatant harvested from two independent Vero cell lines was not enhanced by antibody. Secretion of multiple other inflammatory cytokines was also independent of antibody signaling. However, IL-1β secretion did require NLRP3 and caspase- 1 activity. Immunodepletion of dengue virions from the infectious supernatant confirmed that virus was not the main IL-1β-inducing agent, suggesting that a supernatant component(s) not associated with the virion induced IL-1β production. We excluded RNA, DNA, contaminating LPS, viral NS1 protein, complement, and cytokines. In contrast, purified Vero-derived DENV-2 16681 exhibited antibody-enhancement of both infection and IL-1β induction. Furthermore, C6/36 mosquito cells did not produce such an inflammatory component, as crude supernatant harvested from insect cells infected with DENV-2 16681 induced antibody-dependent IL-1β secretion. This study indicates that Vero cells infected with DENV-2 16681 may produce inflammatory components during dengue virus propagation that mask the virus-specific immune response. Thus, the choice of host cell and viral purity should be carefully considered, while insect-derived virus represents a systemthat elicits antibody- dependent cytokine responses to dengue virus with fewer confounding issues
Model Analysis of Time Reversal Symmetry Test in the Caltech Fe-57 Gamma-Transition Experiment
The CALTECH gamma-transition experiment testing time reversal symmetry via
the E2/M1 mulipole mixing ratio of the 122 keV gamma-line in Fe-57 has already
been performed in 1977. Extending an earlier analysis in terms of an effective
one-body potential, this experiment is now analyzed in terms of effective one
boson exchange T-odd P-even nucleon nucleon potentials. Within the model space
considered for the Fe-57 nucleus no contribution from isovector rho-type
exchange is possible. The bound on the coupling strength phi_A from effective
short range axial-vector type exchange induced by the experimental bound on
sin(eta) leads to phi_A < 10^{-2}.Comment: 5 pages, RevTex 3.
Nonlinear Integer Programming
Research efforts of the past fifty years have led to a development of linear
integer programming as a mature discipline of mathematical optimization. Such a
level of maturity has not been reached when one considers nonlinear systems
subject to integrality requirements for the variables. This chapter is
dedicated to this topic.
The primary goal is a study of a simple version of general nonlinear integer
problems, where all constraints are still linear. Our focus is on the
computational complexity of the problem, which varies significantly with the
type of nonlinear objective function in combination with the underlying
combinatorial structure. Numerous boundary cases of complexity emerge, which
sometimes surprisingly lead even to polynomial time algorithms.
We also cover recent successful approaches for more general classes of
problems. Though no positive theoretical efficiency results are available, nor
are they likely to ever be available, these seem to be the currently most
successful and interesting approaches for solving practical problems.
It is our belief that the study of algorithms motivated by theoretical
considerations and those motivated by our desire to solve practical instances
should and do inform one another. So it is with this viewpoint that we present
the subject, and it is in this direction that we hope to spark further
research.Comment: 57 pages. To appear in: M. J\"unger, T. Liebling, D. Naddef, G.
Nemhauser, W. Pulleyblank, G. Reinelt, G. Rinaldi, and L. Wolsey (eds.), 50
Years of Integer Programming 1958--2008: The Early Years and State-of-the-Art
Surveys, Springer-Verlag, 2009, ISBN 354068274
Physics of Solar Prominences: I - Spectral Diagnostics and Non-LTE Modelling
This review paper outlines background information and covers recent advances
made via the analysis of spectra and images of prominence plasma and the
increased sophistication of non-LTE (ie when there is a departure from Local
Thermodynamic Equilibrium) radiative transfer models. We first describe the
spectral inversion techniques that have been used to infer the plasma
parameters important for the general properties of the prominence plasma in
both its cool core and the hotter prominence-corona transition region. We also
review studies devoted to the observation of bulk motions of the prominence
plasma and to the determination of prominence mass. However, a simple inversion
of spectroscopic data usually fails when the lines become optically thick at
certain wavelengths. Therefore, complex non-LTE models become necessary. We
thus present the basics of non-LTE radiative transfer theory and the associated
multi-level radiative transfer problems. The main results of one- and
two-dimensional models of the prominences and their fine-structures are
presented. We then discuss the energy balance in various prominence models.
Finally, we outline the outstanding observational and theoretical questions,
and the directions for future progress in our understanding of solar
prominences.Comment: 96 pages, 37 figures, Space Science Reviews. Some figures may have a
better resolution in the published version. New version reflects minor
changes brought after proof editin
Cinética do radiofósforo em tecidos de suínos em crescimento alimentados com dietas contendo diferentes fontes de fósforo
Розрахунок та проектування окремого фундаменту будівлі на природній ґрунтовій основі. Методичні рекомендації до виконання практичних завдань та курсового проекту з дисципліни «Механіка ґрунтів, основи і фундаменти» сту- дентами напрямів підготовки 6.060101 Будівництво та 6.050301 Гірництво
Подано методичні рекомендації до виконання практичних завдань та кур-
сового проекту з дисципліни «Механіка ґрунтів, основи і фундаменти» для сту-
дентів напрямів підготовки 6.060101 Будівництво та 6.050301 Гірництво.
Розглянуто порядок проектування фундаменту будівлі мілкого закладан-
ня на природній ґрунтовій основі.
Методичні рекомендації передбачають виконання курсового проекту
«Розрахунок та проектування окремого фундаменту будівлі на природній ґрун-
товій основі» як із викладачем, так і під час самостійної роботи.
Можна використовувати також у підготовці курсового та дипломного про-
ектування
Reforming Watershed Restoration: Science in Need of Application and Applications in Need of Science
Comment on Spracklandus Hoser, 2009 (Reptilia, Serpentes, ELAPIDAE): request for confirmation of the availability of the generic name and for the nomenclatural validation of the journal in which it was published
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