Multiscale statistical analysis of coronal solar activity

Multi-filter images from the solar corona are used to obtain temperature maps which are analyzed using techniques based on proper orthogonal decomposition (POD) in order to extract dynamical and structural information at various scales. Exploring active regions before and after a solar flare and comparing them with quiet regions we show that the multiscale behavior presents distinct statistical properties for each case that can be used to characterize the level of activity in a region. Information about the nature of heat transport is also be extracted from the analysis.Comment: 24 pages, 18 figure

Nuevas aportaciones micropaleontológicas al conocimiento del Neógeno del Baix Llobregat (Barcelona)

Se aportan nuevos conocimientos al estudio geológico y micropaleontológico del subsuelo del área metropolitana de Barcelona, acompañándose de una lista de especies de Foraminíferos que se han encontrado en los materiales neógenos estudiados

Revisión y nuevas aportaciones a la fauna del yacimiento pliocénico de Vilacolum, Girona

En la presente nota se señala por vez primera la presencia de dos gasterópodos en el yacimiento pliocénico de Vilacolum (Girona), Bittium (s.s.), reticulatum DA COSTA y Scala (Hirtoscala) muricata Risso, este último citado por vez primera en el Neógeno español. Se acompaña de un catálogo actualizado de toda la fauna estudiada hasta el presente en dicho yacimiento ampliándose con especies hasta ahora no citadas de Crustáceos y Equínidos halladas por nosotros

The marine Neogene of Eastern Venezuela : a preliminary report

Proceedings of tile 1" R.C.A.N.S. Congress, Lisboa, October 1992The studied marine Neogene-Quaternary of NE Venezuela outcrop in the localities of the Araya peninsula and in the Cubagua and Margarita islands discordant upon a basementof metamorphic rocks and pre-rniocenic sediments. These neogene-quaternary sections belong principally to the Cubagua Formation, which is composed of a lower clayish interval (Cerro Verde Member) and an upper one of calcareous nature (Cerro Negro Member), and to La Tejita and Tortuga formations. The age of this sedimentary interval, based upon analysis of planktonic foraminifera, ranges from the lower part of Late Miocene to Holocene. According to the calcareous nannoflora, in the Cubagua Formation a floral assemblage was identified which goes from the Zone NN10 until the limit of NN16-NN17 zones. The fauna of benthic foraminifera allowed one to establish that the paleoenvironmental evolution of the Cubagua Formation varied from bathial to neritic depths during the Early Pliocene. After a period of elevation an erosion during the greater part of the Pleistocene, water invading the eroded surface depositing upon it the calcareous sequence of the Tortuga Formation

La malacofauna marina de las fases holocenas en la Cueva del Toll (Moià, Barcelona): nuevas aportaciones para el Neolítico nororiental

[EN]: The entrance to the South Gallery of the Toll Cave was discovered in the 40's of the last century. Since then, several works have highlighted the importance of the archaeo-pale-ontological site at both regional and peninsular levels. Focusing on the Holocene levels, the research suggests prolonged use of it, at least from Epicardial times to the late Bronze Age. Among the vast amount of material recovered, we highlight, to the interest of our study, several marine shells. Under the current research project, new specimens have been recovered. Tax-onomic identification shows that they are marine gastropods. The technology, use-wear and chemical analysis suggests that they were anthropically modified by making holes for use as hanging elements. The shells were being tinted with red pigment. The spatial and stratigraphic position of the specimens lead, us to interpret them as part of a single bead, deposited at the bottom of a Neolithic structure.[ES]: La entrada a la Galería Sur de la Cueva del Toll (Moià, Barcelona) fue descubierta en los años 40 del pasado siglo. Desde entonces, las distintas intervenciones realizadas han puesto de manifiesto la importancia del yacimiento arqueo-paleontológico tanto a nivel regional como peninsular. Centrándonos en los niveles holocenos de la cavidad, las investigaciones realizadas indican un uso prolongado de la misma, al menos desde el Neolítico Antiguo, hasta finales del Bronce inicial. Entre la variada cantidad de materiales recuperados destacan por el interés del presente estudio, varios restos de malacofauna marina. En el marco del actual proyecto de investigación, han sido recuperados nuevos ejemplares pertenecientes a las especies Columbella rustica y Nassarius cuvieri. El análisis tecnológico, traceológico y químico de las mismas sugiere que fueron modificadas antrópicamente mediante la realización de perforaciones para su uso, siendo tintadas con pigmentos rojizos. La posición estratigráfica y espacial de los ejemplares nos lleva a interpretar las mismas como parte de un único abalorio, depositado en el fondo de una estructura neolítica.El proyecto de intervención arqueológica esta cofinanciado por el Departamento de Cultura y Medios de Comunicación de la Generalitat de Cataluña.Peer Reviewe

Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein

BACKGROUND: Arabidopsis thaliana copper metallochaperone CCH is a functional homologue of yeast antioxidant ATX1, involved in cytosolic copper transport. In higher plants, CCH has to be transported to specialised cells through plasmodesmata, being the only metallochaperone reported to date that leaves the cell where it is synthesised. CCH has two different domains, the N-terminal domain conserved among other copper-metallochaperones and a C-terminal domain absent in all the identified non-plant metallochaperones. The aim of the present study was the biochemical and biophysical characterisation of the C-terminal domain of the copper metallochaperone CCH. RESULTS: The conformational behaviour of the isolated C-domain in solution is complex and implies the adoption of mixed conformations in different environments. The ionic self-complementary peptide KTEAETKTEAKVDAKADVE, derived from the C-domain of CCH, adopts and extended conformation in solution with a high content in β-sheet structure that induces a pH-dependent fibril formation. Freeze drying electron microscopy studies revealed the existence of well ordered amyloid-like fibrils in preparations from both the C-domain and its derivative peptide. CONCLUSION: A number of proteins related with copper homeostasis have a high tendency to form fibrils. The determinants for fibril formation, as well as the possible physiological role are not fully understood. Here we show that the plant exclusive C-domain of the copper metallochaperone CCH has conformational plasticity and forms fibrils at defined experimental conditions. The putative influence of these properties with plant copper delivery will be addressed in the future

Patrones de participación y logro en un MOOC de Saberes Digitales para Docentes en servicio de México

Participation patterns and completion rates of a MOOC on Digital Knowledge for Teachers with over 8000 students were investigated in this article using descriptive statistics and cluster analysis according to age, gender and previous educational attainment. Results indicate that older and more educated participants obtained higher completion rates and employed more often the discussion forum. No gender differences were obtained. Participation in the course followed a funnel model in which there is a steep decrease of involvement after the first activity which stabilizes in the fifth one. The course rested on a basis of trust assuming that each participant voluntarily enrolled with the purpose of learning and therefore considering his/her self-perception of course performance as one element of overall appraisal is consistent with these courses

Fatty fish consumption and risk of latent autoimmune diabetes in adults

Peer reviewe

App-based COVID-19 syndromic surveillance and prediction of hospital admissions in COVID Symptom Study Sweden

The app-based COVID Symptom Study was launched in Sweden in April 2020 to contribute to real-time COVID-19 surveillance. We enrolled 143,531 study participants (≥18 years) who contributed 10.6 million daily symptom reports between April 29, 2020 and February 10, 2021. Here, we include data from 19,161 self-reported PCR tests to create a symptom-based model to estimate the individual probability of symptomatic COVID-19, with an AUC of 0.78 (95% CI 0.74–0.83) in an external dataset. These individual probabilities are employed to estimate daily regional COVID-19 prevalence, which are in turn used together with current hospital data to predict next week COVID-19 hospital admissions. We show that this hospital prediction model demonstrates a lower median absolute percentage error (MdAPE: 25.9%) across the five most populated regions in Sweden during the first pandemic wave than a model based on case notifications (MdAPE: 30.3%). During the second wave, the error rates are similar. When we apply the same model to an English dataset, not including local COVID-19 test data, we observe MdAPEs of 22.3% and 19.0% during the first and second pandemic waves, respectively, highlighting the transferability of the prediction model