274 research outputs found

    Autoradiographic visualization of the mouse egg's sperm receptor bound to sperm.

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    Saturation magnetostriction and its low-temperature variation inferred for natural titanomaghemites: implications for internal stress control of coercivity in oceanic basalts

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    Highly oxidized titanomaghemite in oceanic basalts often carries remanent magnetization of high coercivity (stability), helping preserve the oceanic magnetic anomaly pattern. We study the source of this high coercivity in four oceanic basalts (from ODP sites 238, 572D, 470A and 556) containing highly oxidized titanomaghemite (titanium content parameter x ≈ 0.55 and oxidation parameter z ≈ 0.9 on average). Most of the titanomaghemite is likely in singledomain grains with uniaxial anisotropy because the ratio of saturation remanence J RS to saturation magnetization Js approaches 0.50 (JRS/JS = 0.46 on average). We show that the uniaxial anisotropy is very likely magnetostrictively controlled through internal stresses σi in the titanomaghemite grains. This allows us to use a novel indirect method to estimate the saturation magnetostriction λS of the titanomaghemite. A saturation remanence J RS is given along the axis of a cylindrical sample of each basalt. Then a small compression σ is applied repeatedly along this axis and the reversible change ∆JRS in JRS is measured. Combining equations from single-domain theory for this piezomagnetic effect and for the sample’s coercive force HC gives λS = 1.39HCJS 1/σ ∆JRS/JRS (using cgs units, or with HC in mT, J S in kA m and σ in Pa). This yields four λS estimates (with ca 50 per cent expected error) ranging from 3 × 10−6 to 10 × 10−6 and averaging 6 × 10−6. Theory for the piezomagnetic effect yields four σ i estimates averaging 2 × 108 Pa. This is similar to the internal stress magnitude thought to be responsible for the high coercivity of ball-milled single-domain titanomagnetite (x ≈ 0.6) and natural single-domain haematite. We also show that cooling to 120 ◦K causes HC J S for each oceanic basalt to vary in approximate proportion to (1− T TC)n with n between 1.9 and 2.0 (where T is temperature and T C is Curie point, both in ◦K). This implies that λS of titanomaghemite with x ≈ 0.55 and z ≈ 0.9 also varies in approximate proportion to (1− T TC)n with n near 1.9 or 2.0 on cooling to 120 ◦K (assuming that σ i remains constant on cooling). Our results support the hypothesis that coercivity (magnetic stability) is often magnetostrictively controlled by internal stresses in the highly oxidized titanomaghemites typical of oceanic basalts older than ca 10 Myr.We suggest that this hypothesis can be further tested by more extensive observation of whether cooling to 120 ◦K often causes HC J S of such basalts to vary in approximate proportion to (1 − T TC)n with n near 1.9 or 2.0

    Multi-Step Ordering in Kagome and Square Artificial Spin Ice

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    We show that in colloidal models of artificial kagome and modified square ice systems, a variety of ordering and disordering regimes occur as a function of biasing field, temperature, and colloid-colloid interaction strength, including ordered monopole crystals, biased ice rule states, thermally induced ice rule ground states, biased triple states, and disordered states. We describe the lattice geometries and biasing field protocols that create the different states and explain the formation of the states in terms of sublattice switching thresholds. For a system prepared in a monopole lattice state, we show that a sequence of different orderings occurs for increasing temperature. Our results also explain several features observed in nanomagnetic artificial ice systems under an applied field.Comment: 16 pages, 11 postscript figure

    Thermal simulation software outputs: a conceptual data model of information presentation for building design decision-making

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    Building simulation outputs are inherently complex and numerous. Extracting meaningful information from them requires knowledge which mainly resides only in the hands of experts. Initiatives to address this problem tend either to provide very constrained output data interfaces or leave it to the user to customize data organisation and query. This work proposes a conceptual data model from which meaningful dynamic thermal simulation information for building design decision-making may be constructed and presented to the user. It describes how the model was generated and can become operational, with examples of its applications to practical problems. The paper therefore contains useful information for software developers to help in specifying and designing simulation outputs which better respond to building designers’ needs

    High doses of medroxyprogesterone as the cause of disappearance of adherence of the zona pellucida to an oocyte

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    The zona pellucida (ZP) is an external glycoprotein membrane of oocytes of mammals and embryos in the early stage of their development. ZP first appears in growing ovarian follicles as an extracellular substance between the oocyte and granular cells. The zona pellucid markedly affects the development and maturation of the oocyte. The morphology of the ZP-oocyte complex allows a more precise determination of the oocyte maturity. According to numerous experimental studies, ZP is essential for preimplantation embryonic development of humans and other mammals. It prevents dispersion of blastomeres and enhances their mutual interactions. ZP is a dynamic structure responsible for the provision of nutrients to early forms of oocytes in mammals. The aim of the present study was untrastructural evaluation of the ZP-oocyte contact during inhibited ovulation. Female white rats (Wistar strain) received a suspension of medroxyprogesterone acetate (MPA) in incremental intramuscular bolus doses of 3.7 mg (therapeutic dose), 7.4 mg and 11.1 mg. The animals were decapitated 5 days after the administration of MPA. Ovarian sections were evaluated under a transmission electron microscope (TEM) Zeiss EM 900. Morphometric analysis of ZP was conducted using the cell imaging system by Olympus. In females exposed to therapeutic doses of MPA, ZP showed the structure of granular-fibrous reticulum of a medium electron density with single cytoplasmic processes originating from the surrounding structures. The oocyte cell membrane generated single, delicate processes directed toward ZP. Microvilli of the oocyte were short and thin. In the group receiving 7.4 mg of MPA, ZP had the structure of a delicate, loose granular-fibrous reticulum, and the oocyte cell membrane generated single microvilli directed toward ZP. In both those groups, the close ZP-oocyte contact was observed. Otherwise, in the group exposed to the highest MPA doses (11.1 mg), thicker and more numerous oocyte microvilli were found, which did not penetrate ZP matrix. They were dense, irregularly separated contour, forming a barrier between ZP and oocyte. The present findings are likely to suggest that MPA has inhibiting effects on the synthesis of binding proteins and causes the loss of the oocyte contact with ZP

    Magnetic self-field effects on current collection by an ionospheric bare tether

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    It was recently suggested that the magnetic field created by the current of a bare tether strongly reduces its own electron-collection capability when a magnetic separatrix disconnecting ambient magnetized plasma from tether extends beyond its electric sheath. It is here shown that current reduction by the self-field depends on the ratio meterizing bias and current profiles along the tether (Lt tether length, characteristic length gauging ohmic effects) and on a new dimensionless number Ks involving ambient and tether parameters. Current reduction is weaker the lower Ks and L*/ Lt, which depend critically on the type of cross section: Ks varies as R5/3, h2/3R, and h2/3 1/4 width for wires, round tethers conductive only in a thin layer, and thin tapes, respectively; L* varies as R2/3 for wires and as h2/3 for tapes and round tethers conductive in a layer (R radius, h thickness). Self-field effects are fully negligible for the last two types of cross sections whatever the mode of operation. In practical efficient tether systems having L*/Lt low, maximum current reduction in case of wires is again negligible for power generation; for deorbiting, reduction is <1% for a 10 km tether and 15% for a 20 km tether. In the reboost mode there are no effects for Ks below some threshold; moderate effects may occur in practical but heavy reboost-wire systems that need no dedicated solar power

    Evolutionary patterns of two major reproduction candidate genes (Zp2 and Zp3) reveal no contribution to reproductive isolation between bovine species

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    <p>Abstract</p> <p>Background</p> <p>It has been established that mammalian egg zona pellucida (ZP) glycoproteins are responsible for species-restricted binding of sperm to unfertilized eggs, inducing the sperm acrosome reaction, and preventing polyspermy. In mammals, ZP apparently represents a barrier to heterospecific fertilization and thus probably contributes to reproductive isolation between species. The evolutionary relationships between some members of the tribe Bovini are complex and highly debatable, particularly, those involving <it>Bos </it>and <it>Bison </it>species for which interspecific hybridization is extensively documented. Because reproductive isolation is known to be a major precursor of species divergence, testing evolutionary patterns of ZP glycoproteins may shed some light into the speciation process of these species. To this end, we have examined intraspecific and interspecific genetic variation of two ZP genes (<it>Zp2 </it>and <it>Zp3</it>) for seven representative species (111 individuals) from the Bovini tribe, including five species from <it>Bos </it>and <it>Bison</it>, and two species each from genera <it>Bubalus </it>and <it>Syncerus</it>.</p> <p>Results</p> <p>A pattern of low levels of intraspecific polymorphism and interspecific divergence was detected for the two sequenced fragments each for <it>Zp2 </it>and <it>Zp3</it>. At intraspecific level, none of neutrality tests detected deviations from neutral equilibrium expectations for the two genes. Several haplotypes in both genes were shared by multiple species from <it>Bos </it>and <it>Bison</it>.</p> <p>Conclusions</p> <p>Here we argue that neither ancestral polymorphism nor introgressive hybridization alone can fully account for haplotype sharing among species from <it>Bos </it>and <it>Bison</it>, and that both scenarios have contributed to such a pattern of haplotype sharing observed here. Additionally, codon-based tests revealed strong evidence for purifying selection in the <it>Zp3 </it>coding haplotype sequences and weak evidence for purifying selection in the <it>Zp2 </it>coding haplotype sequences. Contrary to a general genetic pattern that genes or genomic regions contributing to reproductive isolation between species often evolve rapidly and show little or no gene flow between species, these results demonstrate that, particularly, those sequenced exons of the <it>Zp2 </it>and the <it>Zp3 </it>did not show any contribution to reproductive isolation between the bovine species studied here.</p

    A cold and fresh ocean surface in the Nordic Seas during MIS 11: Significance for the future ocean

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    Paleoceanographical studies of Marine Isotope Stage (MIS) 11 have revealed higher-than-present sea surface temperatures (SSTs) in the North Atlantic and in parts of the Arctic but lower-than-present SSTs in the Nordic Seas, the main throughflow area of warm water into the Arctic Ocean. We resolve this contradiction by complementing SST data based on planktic foraminiferal abundances with surface salinity changes using hydrogen isotopic compositions of alkenones in a core from the central Nordic Seas. The data indicate the prevalence of a relatively cold, low-salinity, surface water layer in the Nordic Seas during most of MIS 11. In spite of the low-density surface layer, which was kept buoyant by continuous melting of surrounding glaciers, warmer Atlantic water was still propagating northward at the subsurface thus maintaining meridional overturning circulation. This study can help to better constrain the impact of continuous melting of Greenland and Arctic ice on high-latitude ocean circulation and climate
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