Estimation of the flux at 1450MHz of OB stars for FAST and SKA

Radio observation is crucial to understanding the wind mechanism of OB stars but very scarce. This work estimates the flux at 1450MHz ($S_{\rm 1.4GHz}$) of about 5,000 OB stars identified by the LAMOST spectroscopic survey and confirmed by the Gaia astrometric as well as astrophysical measurements. The calculation is performed under the free-free emission mechanism for wind with the mass loss rate derived from stellar parameters. The estimated $S_{\rm 1.4GHz}$ distributes from $10^{-11}$Jy to $10^{-3}$Jy with the peak at about $10^{-8}$Jy. This implies that the complete SKA-II can detect more than half of them, and some tens of objects are detectable by FAST without considering source confusion. An array of FAST would increase the detectable sample by two orders of magnitude.Comment: 15 pages. 8 figure

The Private Trade between Japan and China from the Middle Ming to the Beginning of Qing Dynasty

This article will discuss from China side, about the private trades between China and Japan, from the middle Ming to the beginning of Qing Dynasty, during the stage of trade globalization, including the main routes, the businessmen, the specific situations of trades. Moreover, it will discuss the reasons of trades prosperity, and its "Engine for Growth" effect on the two countries\u27 economy and culture.本文从中国方位阐述明朝中叶至清初(1553-1730) 期间，贸易全球化阶段的中日私商贸易的主要航线、贸易商人、贸易商品的情形，并剖释贸易繁盛的原因和贸易对中日两国社会经济、思想文化“增长的发动机"(Engine for Growth) 效应

Research hotspots and trends of fresh e-commerce in China: A knowledge mapping analysis based on bibliometrics

The fresh e-commerce industry has seen a sudden and substantial rise since the outbreak of COVID-19. The rapid development of this industry calls for a comprehensive and systematic review of its research status, hotspots and future trends, which will have significant implications for researchers in related fields. This paper first conducts a current situation analysis of the core literature on fresh e-commerce retrieved from four databases – CNKI, CSSCI, Wanfang and VIP – to categorize the research status of fresh e-commerce in three dimensions: the year of publication, article sources, and distribution of subjects. CiteSpace is then used to perform a bibliometric analysis of the data and to create visualized knowledge maps. The results show that the research on fresh e-commerce can be divided into three stages: rapid development (2012-2015), exploration and transformation (2016-2019), maturity and upgrade (2020-present). At each stage, the research evolves toward diversity and maturity with policy developments and changes in the external environment. Cold chain logistics, business models, freshness-keeping of products and e-commerce are ongoing research hotspots in fresh produce e-commerce, while later studies focus more on the transformation and upgrade of products, logistics, distribution and platforms to better serve consumers’ consumption habits and environmental requirements. This study provides valuable insights for researchers and enterprises who are engaged in the industry and for those who are interested in the development of fresh e-commerce in China

RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy

Prolonged activation of nuclear factor (NF)-кB signaling significantly contributes to the development of colorectal cancer (CRC). New therapeutic opportunities are emerging from targeting this distorted cell signaling transduction. Here, we discovered the critical role of RING finger 138 (RNF138) in CRC tumorigenesis through regulating the NF-кB signaling, which is independent of its Ubiquitin-E3 ligase activity involved in DNA damage response. RNF138(−/−) mice were hyper-susceptible to the switch from colitis to aggressive malignancy, which coincided with sustained aberrant NF-кB signaling in the colonic cells. Furthermore, RNF138 suppresses the activation of NF-кB signaling pathway through preventing the translocation of NIK and IKK-Beta Binding Protein (NIBP) to the cytoplasm, which requires the ubiquitin interaction motif (UIM) domain. More importantly, we uncovered a significant correlation between poor prognosis and the downregulation of RNF138 associated with reinforced NF-кB signaling in clinical settings, raising the possibility of RNF138 dysregulation as an indicator for the therapeutic intervention targeting NF-кB signaling. Using the xenograft models built upon either RNF138-dificient CRC cells or the cells derived from the RNF138-dysregulated CRC patients, we demonstrated that the inhibition of NF-кB signaling effectively hampered tumor growth. Overall, our work defined the pathogenic role of aberrant NF-кB signaling due to RNF138 downregulation in the cascade events from the colitis switch to colonic neoplastic transformation and progression, and also highlights the possibility of targeting the NF-кB signaling in treating specific subtypes of CRC indicated by RNF138-ablation

EUD-MARS: End-User Development of Model-Driven Adaptive Robotics Software Systems

Empowering end-users to program robots is becoming more significant. Introducing software engineering principles into end-user programming could improve the quality of the developed software applications. For example, model-driven development improves technology independence and adaptive systems act upon changes in their context of use. However, end-users need to apply such principles in a non-daunting manner and without incurring a steep learning curve. This paper presents EUD-MARS that aims to provide end-users with a simple approach for developing model-driven adaptive robotics software. End-users include people like hobbyists and students who are not professional programmers but are interested in programming robots. EUD-MARS supports robots like hobby drones and educational humanoids that are available for end-users. It offers a tool for software developers and another one for end-users. We evaluated EUD-MARS from three perspectives. First, we used EUD-MARS to program different types of robots and assessed its visual programming language against existing design principles. Second, we asked software developers to use EUD-MARS to configure robots and obtained their feedback on strengths and points for improvement. Third, we observed how end-users explain and develop EUD-MARS programs, and obtained their feedback mainly on understandability, ease of programming, and desirability. These evaluations yielded positive indications of EUD-MARS

Searches for lepton-flavour-violating decays of the Higgs boson into eτ and μτ in \sqrt{s} = 13 TeV pp collisions with the ATLAS detector

Abstract This paper presents direct searches for lepton flavour violation in Higgs boson decays, H → eτ and H → μτ, performed using data collected with the ATLAS detector at the LHC. The searches are based on a data sample of proton-proton collisions at a centre-of-mass energy s $$\sqrt{s}$$ = 13 TeV, corresponding to an integrated luminosity of 138 fb−1. Leptonic (τ → ℓνℓντ) and hadronic (τ → hadrons ντ) decays of the τ-lepton are considered. Two background estimation techniques are employed: the MC-template method, based on data-corrected simulation samples, and the Symmetry method, based on exploiting the symmetry between electrons and muons in the Standard Model backgrounds. No significant excess of events is observed and the results are interpreted as upper limits on lepton-flavour-violating branching ratios of the Higgs boson. The observed (expected) upper limits set on the branching ratios at 95% confidence level, B $$\mathcal{B}$$ (H → eτ) < 0.20% (0.12%) and B $$\mathcal{B}$$ (H → μτ ) < 0.18% (0.09%), are obtained with the MC-template method from a simultaneous measurement of potential H → eτ and H → μτ signals. The best-fit branching ratio difference, B $$\mathcal{B}$$ (H → μτ) → B $$\mathcal{B}$$ (H → eτ), measured with the Symmetry method in the channel where the τ-lepton decays to leptons, is (0.25 ± 0.10)%, compatible with a value of zero within 2.5σ

Inclusive-photon production and its dependence on photon isolation in pp collisions at s \sqrt{s} = 13 TeV using 139 fb−1 of ATLAS data

Measurements of differential cross sections are presented for inclusive isolated-photon production in pp collisions at a centre-of-mass energy of 13 TeV provided by the LHC and using 139 fb−1 of data recorded by the ATLAS experiment. The cross sections are measured as functions of the photon transverse energy in different regions of photon pseudorapidity. The photons are required to be isolated by means of a fixed-cone method with two different cone radii. The dependence of the inclusive-photon production on the photon isolation is investigated by measuring the fiducial cross sections as functions of the isolation-cone radius and the ratios of the differential cross sections with different radii in different regions of photon pseudorapidity. The results presented in this paper constitute an improvement with respect to those published by ATLAS earlier: the measurements are provided for different isolation radii and with a more granular segmentation in photon pseudorapidity that can be exploited in improving the determination of the proton parton distribution functions. These improvements provide a more in-depth test of the theoretical predictions. Next-to-leading-order QCD predictions from JETPHOX and SHERPA and next-to-next-to-leading-order QCD predictions from NNLOJET are compared to the measurements, using several parameterisations of the proton parton distribution functions. The measured cross sections are well described by the fixed-order QCD predictions within the experimental and theoretical uncertainties in most of the investigated phase-space region