Changing medical student attitudes to patient safety: A multicentre study

Background: Although patient safety is becoming widely taught in medical schools, its effect has been less rigorously evaluated. We describe a multicentre study to evaluate student changes in patient safety attitudes using a standardized instrument, the Attitudes to Patient Safety Questionnaire3 (APSQ3). Methods: A patient safety training package designed for medical students was delivered in the first year and second year in four Australian medical schools. It comprises eight face-to-face modules, each of two hours. Seminars start with an interactive introduction using questions, video and role play, followed by small group break-outs to discuss a relevant case study. Groups are led by medical school tutors with no prior training in patient safety. Students and tutors then reassemble to give feedback and reinforce key concepts. Knowledge and attitudes to patient safety were measured using the APSQ3, delivered prior to safety teaching, at the end of the first and second years and 12 months after teaching ceased. Results: A significant improvement in attitude over time was demonstrated for four of nine key items measured by the APSQ3: value of patient safety teaching; danger of long working hours, value of team work and the contribution patients can make in reducing error. Informal feedback from students was very positive. Conclusion: We showed persistent, positive learning from a patient safety education intervention 12 months after teaching finished. Building on the introduction of patient safety teaching into medical schools, pathways for motivated students such as appropriate electives, option terms and team-based research projects would be of value

Modular Materialisation of Datalog Programs

The semina\"ive algorithm can materialise all consequences of arbitrary datalog rules, and it also forms the basis for incremental algorithms that update a materialisation as the input facts change. Certain (combinations of) rules, however, can be handled much more efficiently using custom algorithms. To integrate such algorithms into a general reasoning approach that can handle arbitrary rules, we propose a modular framework for materialisation computation and its maintenance. We split a datalog program into modules that can be handled using specialised algorithms, and handle the remaining rules using the semina\"ive algorithm. We also present two algorithms for computing the transitive and the symmetric-transitive closure of a relation that can be used within our framework. Finally, we show empirically that our framework can handle arbitrary datalog programs while outperforming existing approaches, often by orders of magnitude.Comment: Accepted at AAAI 201

Generalized quantum measurement

We overcome one of Bell's objections to `quantum measurement' by generalizing the definition to include systems outside the laboratory. According to this definition a {\sl generalized quantum measurement} takes place when the value of a classical variable is influenced significantly by an earlier state of a quantum system. A generalized quantum measurement can then take place in equilibrium systems, provided the classical motion is chaotic. This paper deals with this classical aspect of quantum measurement, assuming that the Heisenberg cut between the quantum dynamics and the classical dynamics is made at a very small scale. For simplicity, a gas with collisions is modelled by an `Arnold gas'.Comment: 11 pages, LaTeX, no figures, title change

Convolution theorems associated with quaternion linear canonical transform and applications

Novel types of convolution operators for quaternion linear canonical transform (QLCT) are proposed. Type one and two are defined in the spatial and QLCT spectral domains, respectively. They are distinct in the quaternion space and are consistent once in complex or real space. Various types of convolution formulas are discussed. Consequently, the QLCT of the convolution of two quaternionic functions can be implemented by the product of their QLCTs, or the summation of the products of their QLCTs. As applications, correlation operators and theorems of the QLCT are derived. The proposed convolution formulas are used to solve Fredholm integral equations with special kernels. Some systems of second-order partial differential equations, which can be transformed into the second-order quaternion partial differential equations, can be solved by the convolution formulas as well. As a final point, we demonstrate that the convolution theorem facilitates the design of multiplicative filters

Henan sheng liang cheng shi gao zhong sheng wen hua ding wei, yin jiu qi wang, zi wao xiao neng yu yin jiu xing wei de yan jiu [Study on the relationship between cultural orientation, alcohol expectancy, self-efficacy, and drinking behavior among senior high school students in two cities in Henan province]

Objective: To explore the relationships between alcohol expectancy, cultural orientation, self-efficacy and drinking behavior to provide theoretical support for the development of education programs aimed at preventing alcohol abuse among adolescents. Methods: An anonymous quantitative survey of 2756 tenth and eleventh grade students in six senior high schools in Zhengzhou and Xinyang city of Henan province was conducted in November 2005 and data was analyzed by SPSS 13.0 software. Results: The overall rate of drinking alcohol among participants was 56.5%. The median score of cultural orientation was 3.25(3.09, 3.42); of alcohol expectancy was 3.02 (2.81, 3.23); and 79.64 (60.36, 93.21) of alcohol self-efficacy. Direct or indirect relationships were found between Chinese traditional cultural orientation, western cultural orientation, alcohol positive expectancy, alcohol negative expectancy, alcohol self-efficacy and alcohol drinking behavior. Lower monthly drinking habit was directly associated with higher self-efficacy and higher negative expectancies, lower positive expectancies and lower western cultural orientation (coefficients = -0.346, -0.282, 0.234, and 0.162 respectively), but not with Chinese cultural orientation variables. Conclusion: The current situation of alcohol drinking among the participants was critical. Drinking behavior seemed most affected by drinking beliefs and cultural orientation, suggesting that the development of education programs should focus on students\u27 beliefs

DNA builds and strengthens the extracellular matrix in Myxococcus xanthus biofilms by interacting with exopolysaccharides.

One intriguing discovery in modern microbiology is the extensive presence of extracellular DNA (eDNA) within biofilms of various bacterial species. Although several biological functions have been suggested for eDNA, including involvement in biofilm formation, the detailed mechanism of eDNA integration into biofilm architecture is still poorly understood. In the biofilms formed by Myxococcus xanthus, a Gram-negative soil bacterium with complex morphogenesis and social behaviors, DNA was found within both extracted and native extracellular matrices (ECM). Further examination revealed that these eDNA molecules formed well organized structures that were similar in appearance to the organization of exopolysaccharides (EPS) in ECM. Biochemical and image analyses confirmed that eDNA bound to and colocalized with EPS within the ECM of starvation biofilms and fruiting bodies. In addition, ECM containing eDNA exhibited greater physical strength and biological stress resistance compared to DNase I treated ECM. Taken together, these findings demonstrate that DNA interacts with EPS and strengthens biofilm structures in M. xanthus

Medical student wellbeing - a consensus statement from Australia and New Zealand

Abstract Background Medical student wellbeing – a consensus statement from Australia and New Zealand outlines recommendations for optimising medical student wellbeing within medical schools in our region. Worldwide, medical schools have responsibilities to respond to concerns about student psychological, social and physical wellbeing, but guidance for medical schools is limited. To address this gap, this statement clarifies key concepts and issues related to wellbeing and provides recommendations for educational program design to promote both learning and student wellbeing. The recommendations focus on student selection; learning, teaching and assessment; learning environment; and staff development. Examples of educational initiatives from the evidence-base are provided, emphasising proactive and preventive approaches to student wellbeing. Main recommendations The consensus statement provides specific recommendations for medical schools to consider at all stages of program design and implementation. These are:Design curricula that promote peer support and progressive levels of challenge to students.Employ strategies to promote positive outcomes from stress and to help others in need.Design assessment tasks to foster wellbeing as well as learning.Provide mental health promotion and suicide prevention initiatives.Provide physical health promotion initiatives.Ensure safe and health-promoting cultures for learning in on-campus and clinical settings.Train staff on student wellbeing and how to manage wellbeing concerns. Conclusion A broad integrated approach to improving student wellbeing within medical school programs is recommended. Medical schools should work cooperatively with student and trainee groups, and partner with clinical services and other training bodies to foster safe practices and cultures. Initiatives should aim to assist students to develop adaptive responses to stressful situations so that graduates are prepared for the realities of the workplace. Multi-institutional, longitudinal collaborative research in Australia and New Zealand is needed to close critical gaps in the evidence needed by medical schools in our region