9 research outputs found
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
- Akoua-Koffi Chantal G.
- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert Mélanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
- Allam Loubna
- Allam Mushal
- Allam Mushal
- Altamura Settimia
- Amar Narjis
- Amenga-Etego Lucas N.
- Amer K. E.
- Amer Khaled
- Amira Souissi
- Amoako Daniel G.
- Amoo Olufemi Samuel
- Amoth Patrick
- Amougou Marie
- Ampofo William K.
- Amuri Adrienne A.
- Amuzu Dominic S. Y.
- Amzazi Saaïd
- Anang Abraham Kwabena
- Anas Abbad
- Andeko Julia C.
- Andersen Kristian
- Andersson Hana Sofia
- Andika Brian
- Andres Moreira-Soto
- Andriam Soa Fy
- Andriamandimby Soa Fy
- Anga Latifa
- Ange Dossou
- Angelov Angel
- Anna-Lena Sander
- Annajr B.
- Anoh Etilé A.
- Anscombe Catherine
- Antwerpen Markus H.
- Anu Campbell
- Anyaneji Ugochukwu J.
- Anyika Chinyere
- Aouni M.
- Appiah Vincent
- Appiah-Kubi Joyce
- Arena Fabio
- Arjaquah Augustina
- Arjarquah A.
- Armand Edang-Minko
- Armanious Riad Mounir
- Armoo Samuel
- Arnaldo Paulo
- Arnold Catherine E.
- Arrouchi Housna
- Artesi Maria
- Aryeetey Sherihane
- Asamoah Jesse Addo
- Asante Ivy A.
- Asare K.M.
- Ashton Philip
- Ashton Phillip
- Asiedu Ernest
- Asiedu-Bekoe Franklyn Egbe
- Asiimwe Stephen
- Askander Omar
- Asmamaw Kominist
- Assane Hamadi
- Assoumou Samira Zoa
- Atiga N.
- Attiku Keren Okyerebea
- Audu Rosemary A.
- Auld A.
- Awandare Gordon A.
- Awinda George
- Awunyo Sena
- Ayansola Oyeronke
- Ayei James
- Ayekaba Mitoha Ondo’o
- Ayivor-Djanie Reuben
- Aymane Bouzidi
- Ayo-Ale B.
- Ayoade F.
- Ayoola Joy
- Ayouba Ahidjo
- Aziz Ramy Karam
- Aziza Amuri
- Azman Andrew
- Aïssi Melchior A. Joël
- Ba-Diallo Awa
- Babatunde Sunday
- Baboo S. B.
- Badjo Ange
- Badou Yvette
- Bagaya Bernard Ssentalo
- Bah Mamadou Saliou
- Bahadoor B. S.
- Bahnassy A.A.
- Bajjou Tahar
- Baker David
- Baker Noah
- Bakhash Shah Mohamed
- Bakry U.
- Balde Aladje
- Balde Aladje
- Balm Michelle
- Bamourou Diané
- Banda R.
- Bane S.
- Barasa Edwine
- Barbet Marion
- Bareng Ontlametse T.
- Barilar Ivan
- Barkat Amina
- Barnes Kayla
- Barreh Guedi Ali
- Bashein Abdulla
- Bassène Hubert
- Batchi-Bouyou Armel L.
- Batchi-Bouyou Armel L.
- Bates Matthew
- Batra Dhwani
- Batra R.
- Bauer Peter
- Baxter Cheryl
- Bayih Abebe Genetu
- Bbosa Nicholas
- Bedford Trevor
- Bediako Yaw
- Bedié
- Bedri Shahinaz.A.
- Behillil Sylvie
- Bejon Philip
- Belarbi Essia
- Belfquih Bouchra
- Belkhir A.B.
- Bellefquih Abdelkrim Meziane
- Beloufa Mohamed Amine
- Belournou Grace Angong
- Ben Alaya Nissaf
- Ben Ayed I.
- Ben Boubaker Ilhem Boutiba
- Ben Boubaker Ilhem Boutiba
- Ben Kahla Alia
- Ben Khelil Jalila
- Ben Moussa Mohamed
- Ben Othman Roua
- Ben Romdhane Habiba
- Ben Sassi Manel
- Ben Sassi Mouna
- Benaissa Elmostafa
- Benhida Rachid
- Benkeroum Samira
- Benkirane Hasnae
- Bennett Andrew J.
- Benrahma Houda
- Bensaid M.
- Bensalem Aicha
- Benyahia Amel
- Bestehorn-Willmann Malena S.
- Bester Phillip A.
- Beyene Getachew Tesfaye
- Bhiman Jinal N.
- Bighignoli B.
- Bikangui Rodrigue
- Bimouhen Abderrahmane
- Bingono Sam O'neilla Oye
- Biscornet Leon
- Bishop-Lilly Kimberly A.
- Bitew Molalegne
- Bitrou S.M.
- Bizard Méline
- Bióté Simão Tchuda
- Blackmore Timothy
- Blakiston Matt
- Bloomfield Max
- Bnouyahia Ikram
- Boatemaa Linda
- Bolajoko Bankole
- Bonney Evelyn Y.
- Bonney Joseph H. K.
- Bonney Kofi
- Bontems Sébastien
- Bootsma Sacha
- Borrmann Steffen
- Boter Marjan
- Boujemla Bouchra
- Bours Vincent
- Boussoukou Ismael Pierrick Mikelet
- Bouzid Amal
- Bouzid Jawad
- Bracchitta Fiorenza
- Brechar Ludivine
- Bridges Daniel J.
- Briese Thomas
- Brisebarre Angela
- Brook Cara
- Bssaibis Fatna
- Budiaki Sylvie L.
- BUHARI Mikhail Olayinka
- Bulimo Wallace D
- Bunga Sudhir
- Butel Christelle
- Butera Yvan
- Bwogi Josephine
- Camara Alimou
- Camara Makhtar
- Campbell Allan
- Campbell Julian
- Cancino Irving
- Candé Adul
- Capel Camille
- Carey Omondi Francis
- Carniel Elisabeth
- Carr Rosina A. A.
- Carri Valeria Delli
- Carvalho Kevin S.
- Cassama Faatu
- Cedola Donatella
- Cer Regina Z.
- Chabert-Consen Marie Madeleine
- Chabuka L. B.
- Chabuka Lucious
- Chambaro H.
- Chammam Sara
- Chamman Sarra
- Chanda D.
- Changula K.
- Charlene Sonal P.
- Chawech H.
- Chenaoui Mohamed
- Chenwi Collins
- Chestakova Irina
- Chgouri Fatima
- Chilufya C.
- Chilufya Moses
- Chimedza Jasper
- Chinedu Ugwu
- Chipimo P.J.
- Chitanga S.
- Chitechi Esther
- Chitenje M.
- Chiwaula M. J.
- Choga Wonderful T.
- Chouati Taha
- Chouikha Anissa
- Christoffels Alan
- Chtourou A.
- Chukwu Chimaobi
- Chukwu G.
- Cigolo Jean-Claude Makangara
- Cisse Barada
- Clarisse Murebwayire
- Colson Philippe
- Comas Iñaki
- Combe Patrice
- Corman Victor Max
- Cortes Carlos
- Cotten Matthew
- Crawford M.
- Crespin Xavier
- Cá Milanca Agostinho
- D'Amore N.
- D'Aprile Annamaria
- Dadi Hailu
- Daghfous Riadh
- Dagnran Anoumou
- Dakka Hanae
- Dal Monego Simeone
- Damaris Matoke-Muhia
- Damena D.
- Damilari Dabiri
- Daniels Rodney S.
- Dao Sounkalo
- Daou Amadou
- Dara Antoine
- Daubenberger Claudia
- David Kumbelembe
- Davids Micheala
- Davies Mary-Ann
- Dawood R.M.
- Dawood Reham
- de Laurent Zaydah R.
- de Ligt Joep
- De Nittis Rosella
- de Oliveira Filho Edmilson F.
- de Oliveira Martins Leonardo
- de Oliveira Tulio
- De Sanctis R.
- de Silva Thushan I
- DeAlmeida Mary
- Debela Alemu Tike
- Delaney Kayla
- Delaporte Eric
- Delerce Jeremy
- Dellagi Koussay
- Deng Guohong
- Deng Lul Lojok
- DeRisi Joseph L.
- Derrar Fawzi
- Descheemaeker Patrick
- Deschenes Michael V.
- Desta Adey Feleke
- Detweiler Angela M.
- Devatchagni Syntyche
- Devaux Christian A.
- Dhaala Beatrice
- Dia Aminata
- Dia Ndongo
- Dia Yacine Amet
- Diab A.
- Diagne Diabou
- Diagne Moussa M.
- Diakite Mandiou
- Diallo Amadou
- Diallo Haby
- Diallo Penda Malhado
- Diallo Sada
- Diarra B.
- Diarra Bassirou
- Diaw Papa Alassane
- Diawara Idrissa
- Dieng Alle Baba
- Dieng Assane
- Diergaardt Azaria
- Diop Mamadou
- Diop Oumy
- Djimde Abdoulaye
- Djingarey Mamoudou Harouna
- Djomsi Dowbiss Meta
- Djontu Jean Claude
- Dobi Paul
- Donati Flora
- Dorkenoo Ameyo
- Doudou Fetouma
- Douffan Messanh
- Doumbia Seydou
- Draper C.
- Dratibi Fred A.
- Drinkovic Dragana
- Drosten Christian
- Duedu Kwabena O.
- Durkin Keith
- Dussart Philippe
- Dussart Philippe
- Dürr Kouriba
- Ebied Fatma
- Ebong Ofonime
- Eckstein Simone
- Edu Emame
- Eggan Stephen M.
- Egli Adrian
- Egoh Ifunanya
- Egyir B.
- Ehlan Amivi
- El Amin Ghizlane
- El ansari Fatima Zahra
- El Atar Jalil
- El Fahime Elmostafa
- El Falaki Fatima
- El Guindy Nancy M.
- El Hady Yassine
- El Jaoudi Rachid
- El Jebari Hanen
- El Mazouri Safae
- El Mrimar Nadia
- El Sayes Mohamed
- El-Duah Philip
- El-Shaqnqery H.
- El-Shesheny Rabeh
- El-Taweel Ahmed
- El-Zayat M.
- Elahmer Omar
- Elalaoui Mly Abdelaziz
- Elannaz Hicham
- Elarab Hoda Ezz
- Elargoubi A.
- Elfihri Mohammed Walid Chemao
- Elgahzaly Hesham
- Elgohary Mohamed Abdel-Salam
- Elguindy Nancy
- Elhadidi Mohamed
- Elhag Khabab A.
- Elhamoumi Siham
- ElHefnawi Mahmoud
- Elhoseiny Mostfa
- Elhoseny M.M.
- Elhosieny F.W.
- Elisabeth Carniel
- Elkhateeb S.M.
- Elkochri Safae
- Ella Kevine Zang
- Ellis Sean
- ElMoussi Awatef
- Elnakib Mostfa
- Eloualid Mjid
- Elouanass M.
- Elouennass Mostafa
- Elroby Ola
- Elsaid Manal Hamdy
- Elsawy Laila
- Elsayed Ahmed
- Elshora Hagar
- Elsissy M.H.
- Elvy Juliet
- Elzagheid Adam I.
- Embaló Bubacar Delgado Pinto
- Emna Gaies
- Emokpae Uyi
- Enatha Mukantwari
- Endjala Nathalia
- Engelbrecht Susan
- Ennibi H.
- Enouf Vincent
- Erameh Cyril
- Erhart Annette
- Eshun Miriam
- Essabbar Abdelomunim
- Essabbar Mouneem
- Essayagh Touria
- Essomba René G.
- Essone Paulin N.
- Estrella Luis A.
- Everatt Josie
- Exler Jan Felix
- Ezzelarab M.H.
- Fadeyi Abayomi
- Fageer Sameira M.
- Fageer Samira M.
- Faggioni G.
- Fahsbender E.
- Fainguem Ndine
- Faisal Muhammad
- Fakayode Oluwatosin
- Fakhfakh Ahmed
- Fall Mbengué
- Faouzi Abdellah
- Faouzia Zemmouri
- Farawyla H.
- Fares Wasfi
- Farghaly Ayman
- Faye Martin
- Faye Ousmane
- Feasey Nicholas
- Fedorov A.V.
- Fekkak Jamal
- Femi Ayoade
- Femi Oladiji
- Femi Saibu
- Fenollar Florence
- Ferjani Asma
- Ferjani Sana
- Fidelia Hinson
- Fikry A.E.
- Fillo S.
- Fki-berrajah L.
- Fki-Berrajah Lamia
- Foda Iman
- Fokam Joseph
- Folarino O.
- Folorunsho Francine
- Foster-Nyarko Ebenezer
- Foudi Martin Maidadi
- Foulkes Benjamin H.
- Fournier Pierre-Edouard
- Fowora Muinah Adenike
- Fowotade Adeola
- Francisco Ngiambudulu M.
- Frans Ndahafa
- Fred Tei-Maya
- Freed Nikki
- Freeman Josh
- Freitas R. H.
- Frempong Hilda Opoku
- Fuh-Neba T.
- Fwoloshi Somda Soro Georgina
- Gaaloul I.
- Gad Ahmed F.
- Gadzama Galadima
- Gaies Emna
- Galal
- Galiwango Ronald M.
- Galvao Bruna
- Garcia Guillermo
- Gardoul Mouhcine
- Gargouri S.
- Gargouri Saba
- Garry R.
- Garus-Oas Nathalia
- Gaseitsiwe Simani
- Gatare Swaibu
- Gaye-Gaye Astou
- Gdoura Mariem
- Gedeon Jude
- Gelanew Tesfaye
- George Uwem E.
- Gerard Izuwayo
- GeurtsvanKessel Corine H.
- Gevao Sahr
- Gharmaz Hamza
- Ghassan Adib
- Ghedira Kais
- Ghita Amalou
- Ghoulame Safae
- Giandhari Jennifer
- Gideon Nsubuga
- Giordani F.
- Girgis Samia Abdou
- Gismondo Maria Rita
- Githii Rachid
- Githinji George
- Gnimadi Thibaut Armel Cherif
- Goba Augustine
- Godwe Celestin
- Goedhals Dominique
- Goldstone R.
- Gomaa C.
- Gomaa Mokhtar
- Goodfellow Ian
- Goredema Alexander
- Gorman Richmond
- Gorova Vivianne
- Gosnell B. I.
- Gottberg A.
- Gouider Riadh
- Grace Chukwa
- Grad Alia
- Grant Donald S.
- Grantz Kyra
- Grayo Solène
- Greninger Alexander
- Guedouar Houssem
- Gueye Abdou Salam
- Gueye Khadim
- Gueye Ousseynou
- Guindo Ibrahima
- Gumbo Hlanai
- Gumede Nicksy
- Guseva N. P.
- Gutema Gadissa
- Gutierrez Ana V.
- Gwayi S.
- Gyamfi Jones
- Gyapong John O.
- Hachid Aissam
- Hadad A.
- Haddad Sonia V.
- Hafez Hala
- Hafez M.M.
- Hailu Getnet
- Halafawy A.
- Halatoko Jacqueline Wemboo Afiwa
- Halilou Ibrahima
- Hamdani T.N.
- Hamdy M.S.
- Hammad M.
- Hammami A.
- Hammer David
- Hamza Ghamaz
- Hamzaoui Zaineb
- Handrick Susann
- Happi Anise N.
- Happi Christian
- Harding Doris
- Harvey R.
- Hassan Iman Abdillahi
- Hassan R.
- Hassan W.
- Hassany Mohamed
- Hawi Adede
- Hayette Marie-Pierre
- Heikel Jaafar
- Hellemans Jorn
- Helmy Sherine
- Hemlali Mouhssine
- Henson Sondes
- Heraud Jean-Michel
- Herring Belinda L.
- Hicham Charoute
- Hicham Elannaz
- Hihi Nardjes
- Hilali Abderraouf
- Hilali Farida
- Holland LaRinda A.
- Hoornaert Laurien
- Hope Virginia
- Hosch Salome
- Houda Harmak
- Houechenou Rotimi Myrabelle Avome
- Houhamdi Linda
- Hounkanrin Gildas
- Hounkpatin Benjamin
- Howard Julia
- Hsiao Marvin
- Hsiao Nei-yuan
- Hsu Sharon
- Huang Meei-Li
- Huddleston John
- Hultquist Judd F.
- Hussein Salah Eldin
- Ian Lipkin W.
- Ibrahim Muntaser elTayeb
- Ibrahim Samira F.
- Ibrahim Tomade A.M.
- Ige F.A.
- Iguosadolo Nosamiefan
- Ihazmad Hassan
- Ihekweazu Chikwe
- Iknane A.A.
- Imam Zeinab S.
- Inglês L.
- Inndi Rui
- Intyre Leigh-Anne MC
- Iranzadeh Arash
- Ismael Nalia
- Ismail A.
- Ismail Arshad
- Isong Josiah Ayoola
- Issa Zoukaneirii
- Iwalokun Bamidele
- Iyanu Fred-Akintunwa
- Jain Komal
- Jalal D.
- Jalal Nourlil
- Jalloh Simbirie
- Jamal Fekkak
- Jambo Kondwani
- James Ayorinde Babatunde
- Jannoo N.
- Jefferies Sarah
- Jegede-Williams Anu
- Jelly Lauren
- Jerome Keith R
- Jimoh Yusuf
- Jiménez-Serrano Santiago
- Jo Wendy Karen
- JOEL Ireoluwa Yinka
- Johane Shirley
- Johnson Adeniji A.
- Johnson Bankole
- Joloba Moses
- Joseph Rageema
- Jouali Farah
- Jumaa A.B.
- Juru Agnes
- Kabamba Gabriel
- Kabanda Alice
- Kabatesi Francisca
- Kabbaj Hakima
- Kaboré Firmin
- Kacem Imen
- Kadjo Herve Albéric Adje
- Kagnissode Sidonie A.M.
- Kagoné Thérèse
- Kakai Clement G.
- Kalantar K.
- Kaleebu Pontiano
- Kamal Mohamed
- Kamara Santigie
- Kamel Mina
- Kamga Rodrigue
- Kamoun S.
- Kamulegeya Rogers
- Kandaswamy Krishna Kumar
- Kandeil Ahmed
- Kandeil Ahmed
- Kane Mouhamed
- Kane Ndéye Coumba Touré
- Kanjau Lilian
- Kanjerwa Oscar
- Kanteh Abdoulie
- Kanyerezi Stephen
- Kapata Nathan
- Kapata P.C.
- Kapaya F.
- Kapin'a M.
- Karidioula Safiatou
- Karim Wasim Abdul
- Karray Hakim H.
- Karray Hela
- Kartti Souad
- Kasambara W.
- Kasmy Zohour
- Kassab Reham
- Kassim Samar Kamal
- Katabazi Ashaba Fred
- Katagirya Eric
- Kateete David Patrick
- Katyshev A.D.
- Kavunga-Membo Hugo
- Kay Gemma L.
- Kayali Ghazi
- Kayed Ahmed E
- Kayeyi N.
- Kayiwa John T.
- Kayuki Charles
- Kazeem Akano
- Kazorina E.V.
- Kebabonye Malebogo
- Keita Alpha K.
- Keita Mamadou Bhoye
- Keita S.
- Keita Sakoba
- Kemi Adedotun-Sulaiman
- Kepler Lenora M.
- Kezakarayagwa Eric
- Khaireh Bouh Abdi
- Khalid Ennibi
- Khalifa Mohamed K.
- Khamadi Samoel Ashimosi
- Khan Adam K.
- Kharat N.
- Khardine Fayez
- Khardine Fayez Ahmed
- Kharrat Maher
- Khumalo Z.
- Kibet Gilbert
- Kiconco Jocelyn
- Kidane Eleni
- Kiemdé Franklin
- Kifude Carol
- Kigozi Edgar
- Kiiza Ronald
- Kim L.
- Kimita Gathii
- Kimotho J.
- Kingsley Ojide C.
- Kingsley Robert A.
- Kirimunda Samuel
- Kiritu Edward
- Kleinhans Bronwyn
- Kohoun Rodrigue K.
- Koita Demba
- Koivogui Joel
- Koka Hellen
- Kolomoets E.V.
- Kone Amadou
- Konou Abla A.
- Konstantinus Iyaloo S.
- Koné Amariane
- Koné Amariane M. M.
- Kooepile Legodile
- Koopmans Marion
- Koskei Edith
- Kossi Komlan
- Kotey Erasmus
- Kouriba Bourema
- Kourouma Kaba
- Kpeli Grace S.
- Krasnov Y.M.
- Krasnov Ya.M.
- Kritsky A.A.
- Kujabi Mariama
- Kumordjie Selassie
- Kutkat Omnia
- Kutyrev V.V.
- Kwasah Lorreta
- Kwenda S.
- Kyei George B.
- Laamarti Meriem
- Laamrti Rokaia
- Laatiris Abdelkader
- Ladhari Hafsia
- Lagare Adamou
- Laguda-Akingba Oluwakemi
- Lahlou Amine Idriss
- Lahlou Idriss-Amine
- Lahlou Kitane Driss
- Lako Richard Lino Loro
- Lalemi Mary
- Lambisia Arnold W.
- Lamboni Lallepak
- Lamiae Belayachi
- Langat Sombo
- Laraqui Abdelilah
- Laryea Dennis
- Latif Elwaleed M. Elamin Sara A.I
- Latifa Anga
- Layibo Yasser
- Le Viet Thanh
- Le-Viet Thanh
- Lee Justin
- Lee Kwok
- Leendertz Fabian
- Lefrançois Louise
- Lekana-Douki Bernard
- Lekana-Douki Sonia
- Lell Bertrand
- Lelo Eric A.
- Lemoine Frederick
- Lemtudo Alan
- Lesego Kuate-lere
- Lesetedi Onalethata
- Lessells Richard
- Lessler Justin
- Leta D.
- Leta Dereje
- Letaief A.
- Levasseur Anthony
- Leye Nafisatou
- Li Zhenghui
- Liberator Paul
- Liboro G.
- Licastro Danilo
- Lieu Vivi Hue-Trang
- Lim Efrem S.
- Lima Mendonça Maria da Luz
- Limbaso Samson Konongoi
- Lin L.
- Lin Michelle
- Lindsey Benjamiin B.
- Linh Le Thi Kieu
- Lipsi Maria Rosaria
- Lissauer Sam
- Lissom Abel
- Lista F.
- Livo Esemu
- Liwewe M.M.
- Liyai Rehema
- Lo Gora
- Lo Mamadou Beye Cheikh Ibrahima
- Lockman Shahin
- Lodiongo Dennis Kenyi
- Lojuan Abe
- Lokilo Emmanuel
- Long Kyle A.
- Lontchi Roméo Aimé Laclong
- Lorenzo-Redondo Ramy
- Loucoubar Cheikh
- Lule Daniel B.
- Lumembe Raphael
- Luo Hu
- Luquette Andrea E.
- Lusamaki Eddy K.
- Lutalo Tom
- Lutucuta Silvia
- Lutwama Julius J.
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- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo Arsène
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
السلوك الكهروكيميائي لبعض مشتقات البيريميدينات : الأختزال البولاروجرافي لـ 1، 3 - ثنافي ميثيل - 2 ، 4 ، 6 (IH, 3H, 5H ) بيريميد ين ثلاثي الكيتون و5 -فينيل آزو
- Publication venue
- 'Qatar University'
- Publication date
- 01/01/1994
- Field of study
The polarographic behaviour and spectrophotometric pKa of 1,3-dimethyl barbituric acid and 5-phenylazo substituted products were investigated in buffer solution of pH ~ 2-11. The results revealed an azo form of the substituted products, a mechanism for the electroreduction pathway was suggested. Half wave potentials showed fair correlation with o constants while pKa showed practically no dependence on substitutes.درس الاختزال البولاروجرافي لـ 3.1 - ثنائي ميثيل حمض البربتيوريك (I) وكذْلك 3.1 ثنائي ميثيل - 5 - فينيل اَزو حمض البربتيوريك في محاليل منظمة ذات رقم هيدروجين 2-40,11 % (حجم /حجم ) كحولية (II) وأوضح ا لاختزال البولاروجراني ل (I) وجود موجه اختزالية لمجموعة كيتون واحدة . وبالنسبة ل (II) سجلت النتائج موجتين اختزاليتين الأولى (الاكثر إيجابية) لمجموعة الآزو والثانية (الاكثر سالبية) لمجموعة كيتون واحدة . وقد أقترح نسق الاختزال الكهربي لكلا المركبين . كما درس تأثير المجموعات الاستبدالي على كلِ من جهود نصف الموجه وقيم ثابت التأين الحمضي pkd لتباين مدى انطباق علاقات الطاقَة الحرة الخطية على المركبات موضع الدراسة
Novel freeze-dried DDA and TPGS liposomes are suitable for nasal delivery of vaccine
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 06/09/2017
- Field of study
There is a pressing need for effective needle-free vaccines that are stable enough for use in the developing world and stockpiling. The inclusion of the cationic lipid DDA and the PEG-containing moiety TPGS into liposomes has the potential to improve mucosal delivery. The aim of this study was to develop stable lyophilized cationic liposomes based on these materials suitable for nasal antigen delivery.
Liposomes containing DDA and TPGS were developed. Size and zeta potential measurements, ex vivo, CLSM cell penetration study and cell viability investigations were made. Preliminary immunisation and stability studies using ovalbumin were performed.
The liposomes exhibited suitable size and charge for permeation across nasal mucosa. DDA and TPGS increased tissue permeation in ex vivo studies and cell uptake with good cell viability. The liposomes improved immune response both locally and vaginally when compared to i.m administration or control liposomes delivered nasally. Additionally, the lyophilized products demonstrated good stability in terms of Tg, size and antigen retention.
This study has shown that the novel liposomes have potential for development as a mucosal vaccine delivery system. Furthermore, the stability of the lyophilized liposomes offers potential additional benefits in terms of thermal stability over liquid formats
تردد مجموعة آزو - هيدرازو : التثبت من الوجود في إحدى الصورتين من دراسات الإختزال البولاروجرافي والداله الحمضية لبعض المركبات اللاحلقيه الحاويه لمجموعة الاكزيم
- Publication venue
- 'Qatar University'
- Publication date
- 01/01/1994
- Field of study
Potentiometric pKa and polarographic behaviour of l,3-indandione-monoxime-2-phenyl azo and four of its substituted derivatives were investigated in buffer solution of pH -2-12. The results showed that the compounds are in the azo-form, where its reduction wave precedes that of the oxime. A mechanism for the electrodic processes was proposed. Half-wave potentials showed fair correlation with Hammett's s constants while pKa is practically independent.درس الاختزال البولاروجرافي وكذلك ثابت التأين الحمضي لـ 1،3 - إندان دايون - أحادي الأكزيم وكذا أربعة من مشتقاته الاستبدالية في محاليل منظمه ذات رقم هيدروجيني 2 - 11 . وقد أوضحت النتائج وجود المركبات في صوره الآزو نظراً لاختزال هذه المجموعات عند جهود أكثر إيجابية عن مجموعة الأكزيم . وقد أقترح نسخه للاختزال الكهربي للمركبات عند قطب الزئبق المتناقط . وعكست النتائج إنطباق علاقات الطاقة الحرة الخطية لقيم جهود نصف الموجه وعدم انطباقها لقيم ثابت التأمين الحمضي
Novel freeze-dried DDA and TPGS liposomes are suitable for nasal delivery of vaccine
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Global Incidence and Risk Factors Associated With Postoperative Urinary Retention Following Elective Inguinal Hernia Repair
- Author
- Ali
- A. Rady Ahmed Hassan
- Aamir Faiqa B.
- Ababneh Hazim Sameer Mohammad
- Abaidalla Ahmed Faraj
- Abd Al-Fattah Mohammed
- Abd El-razik Sally Ahmed
- Abdelfattah Mohamed S.
- Abdelgalil Mahmoud Shaban
- Abdelhaleem Ibrahim A.
- Abdelmageed Abdelfatah A.
- Abdelwahid Elharith H.
- Abdulhamid Salaheddin M.
- Abdullah Areeba
- Abdullah Mohammad A.
- Abdullah Weaam M.
- Abdulmonem Aya Abdulilah
- Abdulwahed Eman A.
- Abelevich Alexander
- Abo Ghanima Shymaa M.
- Abotaleb Khadega
- Abozid Anwaar
- Abu Jayyab Mustafa A.
- Abu Reyash Tamara K.
- Abu-Arish Hamdoon
- Abu-Ismail Luai
- Abubakr Muhammad
- Abufaraj Mohammad
- Abuleil Amro
- Abuzeid Issa A.
- Adesunkanmi Abdul Hafiz O.
- Adeyeye Ademola Adetoyese
- Adinolfi Elvira
- Adwin Zainal Z.
- Afeikhena Ehis
- Agalianos Christos
- Ahmad Abrar
- Ahmad Hasan Y.
- Ahmad Shahzaib
- Ahmad Sharifa
- Ahmed Fathil Ida Nadiah
- Ahmed Samar G.
- Ahmed Shaheer
- Ahonkhai Irele Ifijeh
- Aimon Sibgha
- Aiolfi Alberto
- Ajekwu Samuel Chibuzo
- Aketch Martin Safari
- Akhtar Aamena
- Akhtar Hamza
- Akram Muhammad U.
- Aktas Ahmed
- Al Bastaki Aysha
- AL Hamoud Mohammad A.
- Al Sagheir Eman
- Al Shareeda Mohamad
- Al-Aydi Tala
- Al-Dhaheri Manal Jamal
- Al-Eryani Fatima
- Al-Eryani Salwa
- Al-Hajj Al-Fakih Wadhah Ahmed
- Al-Juaifari Maytham A.
- Al-Kubaisy Manolia
- Al-Nagdy Mohamed
- Al-Naggar Hamza
- Al-Saba'a Yousef K.
- Al-Shami Khayry
- Al-Shehari Mohammed
- AL-Wajeeh Ghadeer
- Alaa Sherif
- Alabad Madian
- Alabd Husayn M.
- Alahmad Ziad
- Alam Mansoor
- Alameen Hind
- Alaniz Alday Maria Jimena
- Alannaz Omar
- Alansary Marwa N.
- Alarabi Rehab
- Alasawdeh Hadeel
- Albaraesi Mohammed N.
- Alberca Páramo Ana
- Alberich Prats Marta
- Aldawoody Hogir I. R.
- Aldressi Wafa
- Alemad Shada
- Alfa Yakubu
- Alghareeb Rafah
- Alhaj Ahmad
- Alharazin Mohammed
- Alhasan Hasan
- Ali Ali
- Ali Ebrahim M.
- Ali Farjad
- Ali Wasaq
- Aliskander Fater
- Aljaber Ahmad
- Aljamal Sarah
- Alkahlout Dana M.
- Alkaseek Akram Mohammed
- Alkomi Saja
- Allen-Brough Chelsea
- Almasarweh Sami A.
- Almokdad Fares Kh.
- Almugaddami Ayman
- Aloulou Mohammad
- Alozai Muhammad Ilyas
- Alqassab Mohammed K.
- AlQatta Wail M.
- Alrayes Bourhan M. H.
- Alsayadi Ramzi
- Alshaikh Bushra Hussein
- Alshareea Entisar
- Alsmail Mohamed H.
- Alsori Mohamed
- Alvarado-Hurtado Ricardo
- Alvarez Cuiñas Ana
- Alvarez-Lozada Luis Adrian
- Alwis Weerakkodige Mithun Chamindaka
- Amer Fatima M.
- Amnaina Mohamed G.
- Anastasi Alessandro
- Andreuccetti Jacopo
- Andrews Emmet
- Anele Christopher Obinna
- Antonaya Rubia Eva
- Antonopoulou Maria Ioanna
- Antropoli Carmine
- Anwar Muhammad Idrees
- Apelian Shant N.
- Aprea Giovanni
- Arbi Fawad M.
- Arnaout Ahmad Y.
- Arnaout Khaled
- Arrambide-Garza Francisco J.
- Arthur Thomas
- Asghar Tofique
- Ashfersh Mohamed
- Asif Aiza
- Askar Aamal
- Asla Amir F.
- Asla Amir Fathi
- Atatra Khalil O.
- Attiya Omar
- Auchterlonie Rowan
- Avellaneda Nicolás L.
- Awad Ahmed K.
- Awadi Sajeda
- Awwad Amjad H.
- Ayaz Ali Amrat
- Azzam Muayad
- Bagaglini Giulia
- Bagrjancev Maxim
- Bahroun Sumayyah G.
- Baili Efstratia
- Bakeer Hibah Bileid
- Bakhtiar Mahnoor
- Balasubramanian Ishwarya
- Baldini Edoardo
- Balla Andrea
- Balluerca Alba María
- Balogun Simon Adewale
- Bandara Ginimal Bandaralage Kavinda Deshapriya
- Bani Hani Mohammad
- Barka Sharf
- Barnes Tracey
- Barry Kevin
- Bashir Muhammed
- Bazaev Andrey
- Bean Orlagh
- Bennett Kathleen E.
- Biala Marwa
- Biancafarina Alessia
- Biel Arrufat Alex
- Bissett Ian P.
- Boccia Olivia
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- Canonico Giuseppe
- Cantürk Nuh Zafer
- Capolupo Gabriella T.
- Carannante Filippo
- Carganico Giacomo
- Caricato Marco
- Carmignani Francesco
- Carrara Giulia
- Carroll Paul
- Castaldi Antonio
- Cavaliere Davide
- Cervera Celdrán Iria
- Chan Kin Yik
- Charalabopoulos Alexandros
- Chatzimavroudis Grigorios
- Chavarrías Torija Nuria
- Chawla Tabish
- Chong Nicole
- Chrysos Emmanuel
- Chua Irene
- Chubukova Natalia
- Clancy Cillian
- Clarizia Guglielmo
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- Colás-Ruiz Enrique
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- Corcione Francesco
- Creavin Ben
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- de la O-Escamilla Manuel E.
- De Luca Marcello
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- De Prizio Marco
- Dean Yomna
- Deeknah Abdulqudus
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- Demirli Atici Semra
- Dhannoon Amenah
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- Egdeer Amin
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- El-Deeb Amr M.
- El-Mansoury Tarek M.
- El-Taher Ahmed K.
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- Elhadi Muhammed
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- Elhajdawe Fras A. D.
- Elliott Jessie A.
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- Elsaadany Reem
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- Eltaeb Khalid F.
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- Estraviz- Mateos Begoña
- Ewedah Moataz
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- Fakhar Samra
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- Farag Marina
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- Farhan Emaan
- Farinelli Pablo Alberto
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- Feo Carlo V.
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- Galal-Eldin Sami
- Gallo Gaetano
- Galun Danijel
- García Domínguez Antonio
- García López de Goicoechea David
- Garrahy Darragh
- Garvin Joseph
- Ghaith Hazem S.
- Ghamri Nusr
- Ghanem Maha
- Ghannam Mohammad Maen
- Ghatwary Ahmed M.
- Ghazal Ahmad
- Ghmagh Reem
- Giacaman Yazan
- Gidiem Doaa
- Gil Barrionuevo Marta
- Gil Gomez Vicente
- Gill Sonia
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- Girardi Martina
- Giraudo Giorgio
- Gjam Fatima Z.
- Gomaty Jamal M.
- Gonzalez Guerreiro Judit
- Gonzalez-De Miguel Melania
- Gortázar de las Casas Sara
- Goya María M.
- Grande Michele
- Grassia Michele
- Grimaldi Luciano
- Grinlinton Megan
- Guadagni Simone
- Guboug Ali
- Guevara Martínez Jenny
- Guldogan Cem E.
- Gundogdu Emre
- Güler Sertaç Ata
- Güner 
- Hai Arrham
- Haider Sohaib
- Haij Manal Zain Mohammed
- Halwani M. Yasser
- Hamdan Alaa
- Hameed Fahd Mudassar
- Hamid Hytham K. S.
- Hanly Ann
- Hannigan Amy
- Hardy Niall P.
- Harmston Christopher
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- Hasiata Vilingatoni
- Hassaan Mohamad
- Hassan Bassam
- Hassan Luden Saif Aldawla
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- Hasson Hussain
- Hasson Mohammad
- Hechtl Daniel
- Hegazy Mohammed G.
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- Helles Ameer A.
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- Herdan Mohamed O.
- Herrero López Imanol
- Hesham Yousef
- Hevia Falú Ramiro
- Hill Arnold D. K.
- Himi Ahmed A.
- Hokenek Ummahan Dalkilinc
- Hoti Emir
- Huang Dora
- Huilca Luis F
- Hussain Akbar
- Hussein Reema A.
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- Ibrahim Hamza
- Idris Alhaj O.
- Ijaz Muhammad Tayyab
- Ikechukwu Ulasi Bartholomew
- Il Haddad Haifaa
- Ioannidis Argyrios
- Iqbal Aqsa
- Iruthayanathar Andru Nitharasan
- Isik Arda
- Ismail Ruba S.
- Jabbar Naveed
- Jacob Prem Thomas
- Jamal Muhammad Asad
- Jamaluddin Muhammad
- Jamel Wael
- Jamil Soomal
- Jamous Hussam
- Jaralla Nasir
- Jarkas Bakri T.
- Jarullah Furqan A.
- Javaid Amna
- Javed Arwa
- Javed Farhan
- Javeed Muhammad Hassan
- Jayarajah Umesh
- Jiang Shuwen
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- Joseph Nejo
- Joshi Prabesh
- Joyce William P.
- Juma Isam
- Kalfountzos Christos
- Kamour Khaula
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- Karim Muhammad Qaisar
- Karunarathne Rathnayake Mudhiyanselage Dulanee
- Kavalieratos George
- Kayali Ahmad Amir H.
- Kayali Hasan F.
- Kazzaz Ranim
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- Kelly Orlaith
- Kennedy Czara
- Kersik Alessia
- Khader Abdellatif
- Khalafalla Ashraf
- Khalid Noor
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- Khamaj Malak
- Khamees Almu'atasim
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- Korkolis Dimitrios
- Kotoreni Georgia
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- Kozadinos Alexandros
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- Kudra Danial Aghyad
- Kumar Yash
- Kykalos Stylianos
- Ladoukakis Aristeidis
- Laghari Sundas
- Laila Aya A. N.
- Landaluce-Olavarria Aitor
- Lapolla Pierfrancesco
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- Latif Javed
- Lederhuber Hans
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- Lim Sean T.
- Lin Anthony
- Lincango Naranjo Eddy P
- Lionetti Ruggero
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- Lopez Juan Cruz
- López Borao Jaime
- Lucchi Andrea
- Luffarelli Paolo
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- Marjan Iqra
- Maroulis Ioannis
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- Martin Sean T.
- Marwan Abdulrhman
- Masri Ruqaya
- Masroor Layiba
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- Matías-García Belén
- Mazza Marcodomenico
- McCormack Tom
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- Mohamed Islam M.
- Mohammad Mazen
- Mohammed Sabir Fatima
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- Mostafa Mohamed
- Mostafa Omar
- Mrissa Yassine
- Msameh Renad
- Mulita Francesk
- Muñoz-Maldonado Gerardo E.
- Murgese Alessandra
- Musa Keffi Mubarak
- Muse Samantha
- Naana Reyam
- Nabi Nauman
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- Nafea Ahmed
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- Naqi Syed Asghar
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- Omar Mohammed A.
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- Omon Henry Ehidiamen
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- Osman Osama S.
- Otaky Mohammad Baraa
- Otero de Pablos Jaime
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- Pagès-Valle Naila
- Palomba Giuseppe
- Palumbo Alessio
- Pantea Stelian
- Pata Francesco
- Pata Francesco
- Patrone Renato
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- Peirce Colin
- Pellino Gianluca
- Pertile Davide
- Petrocca Sergio
- Petrucciani Niccolò
- Picardi Biagio
- Pinotti Enrico
- Pipitone Federico Nicoletta Sveva
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- Porcelli Francesco
- Povo Ana
- Prieto La Noire Fernando
- Proud David
- Puccioni Caterina
- Putortì Antonella
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- Quiroga-Garza Alejandro
- Raftery Nicola
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- Rodríguez Gómez Lorena
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- Rostum Zuhair
- Roy Dorina
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- Sasia Diego
- Sawas Fatima
- Sayed Hafez Somaya Z. E
- Sánchez-Rubio María
- Scabini Stefano
- Schimera Antonio
- Schizas Dimitrios
- Scolaro Roberta
- Scorsi Alessandro
- Selvaggi Francesco
- Selvaggi Lucio
- Senhuri Alrayah E.
- Serrano-Navidad Monica
- Shaaban Abdelrahman
- Shafi Mahnoor
- Shah Syed Faraz Ali
- Shahab Tooba
- Shahbaz Usama
- Shaheen Ahmed
- Shalaby Mostafa
- Shami Sarah M.
- Shams Marvi
- Shanahan Ben
- Sharifa Mohammad
- Shehata Eslam S. A. M.
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- Shulman Natassia
- Shumrakh Saeed K.
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- Silva Cláudio
- Skroubis Georgios
- Soeda Seminario Isami
- Solaini Leonardo
- Soldevila-Verdeguer Carla
- Soriero Domenico
- Soto-Schütte Sonia
- Sountoulides Petros
- Spoletini Domenico
- Srinivasan Madhu
- Stafford Anthony T.
- Sueiras Gil Albert
- Swindon Daisy
- Syllaios Athanasios
- Şahin Enes
- Şimşek Turgay
- Taha Sandy A.
- Tahir Izza
- Taktuk Salah S.
- Talpai Tamás
- Tammo Shergal
- Tanas Yousef
- Tarky Alhashash Ahmad
- Tasis Nikolaos
- Tatar Ozan Can
- Teker Kenan
- Telha Ghassan K.
- Telha Khaled A.
- Teng Roy
- Teoh Jeremy Y. C.
- Thompson-Fawcett Mark W.
- Tolani Musliu Adetola
- Toomey Desmond
- Torchiaro Marco
- Toubasi Ahmad A.
- Toum Fthelrahman M.
- Ukrani Ronika Devi
- ul Haq Syed Atif
- Umer Farooq
- Uprak Tevfik Kıvılcım
- Ur Rehman Sheeraz
- Vailas Michail
- Valderrabano Gonzalez Santiago
- Vallet Fernandez Josep
- Vannelli Alberto
- Varghese Chris
- Vázquez-Melero Alba
- Vignati Barbara
- Vigutto Gabriele
- Wang Huaxi
- Waqar Usama
- Weeratunga George
- Winter Des C.
- Winter Des C.
- Wong Benjamin Ngie Xiong
- Xenaki Sofia
- Xu William
- Y. Aljabarein Osama
- Yaghoub Ali Abdulhafiz
- Yang Wah
- Yanishev Alexey
- Yaqoob Sadia
- Yaqub Aimen
- Yasin Fawzi Hesham
- Younes Eman
- Youssef Hadeer M. S.
- Zahid Muhammad
- Zahid Sufian M.
- Zahran Ahmed A. A. A
- Zalf Kamal
- Zarin Mohammad
- Zawahra Aya
- Zayat Hussein
- Zayat Mohammed A.
- Zevallos-Quiroz Julio
- Zheng Helen
- Zivanovic Marko
- Zwain Yasir A.
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Importance Postoperative urinary retention (POUR) is a well-recognized complication of inguinal hernia repair (IHR). A variable incidence of POUR has previously been reported in this context, and contradictory evidence surrounds potential risk factors.Objective To ascertain the incidence of, explore risk factors for, and determine the health service outcomes of POUR following elective IHR.Design, Setting, and Participants The Retention of Urine After Inguinal Hernia Elective Repair (RETAINER I) study, an international, prospective cohort study, recruited participants between March 1 and October 31, 2021. This study was conducted across 209 centers in 32 countries in a consecutive sample of adult patients undergoing elective IHR.Exposure Open or minimally invasive IHR by any surgical technique, under local, neuraxial regional, or general anesthesia.Main Outcomes and Measures The primary outcome was the incidence of POUR following elective IHR. Secondary outcomes were perioperative risk factors, management, clinical consequences, and health service outcomes of POUR. A preoperative International Prostate Symptom Score was measured in male patients.Results In total, 4151 patients (3882 male and 269 female; median [IQR] age, 56 [43-68] years) were studied. Inguinal hernia repair was commenced via an open surgical approach in 82.2% of patients (n = 3414) and minimally invasive surgery in 17.8% (n = 737). The primary form of anesthesia was general in 40.9% of patients (n = 1696), neuraxial regional in 45.8% (n = 1902), and local in 10.7% (n = 446). Postoperative urinary retention occurred in 5.8% of male patients (n = 224), 2.97% of female patients (n = 8), and 9.5% (119 of 1252) of male patients aged 65 years or older. Risk factors for POUR after adjusted analyses included increasing age, anticholinergic medication, history of urinary retention, constipation, out-of-hours surgery, involvement of urinary bladder within the hernia, temporary intraoperative urethral catheterization, and increasing operative duration. Postoperative urinary retention was the primary reason for 27.8% of unplanned day-case surgery admissions (n = 74) and 51.8% of 30-day readmissions (n = 72).Conclusions The findings of this cohort study suggest that 1 in 17 male patients, 1 in 11 male patients aged 65 years or older, and 1 in 34 female patients may develop POUR following IHR. These findings could inform preoperative patient counseling. In addition, awareness of modifiable risk factors may help to identify patients at increased risk of POUR who may benefit from perioperative risk mitigation strategies
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- Author
- A Nizarudeen
- Aalem Hajer Abd Alhamed
- Ababneh Hazim
- Abbas Ahmed
- Abbas Aram
- Abbas Hussain
- Abbasi Arezou
- Abbassi Fariba
- Abbasy Jibran
- Abbood Ali H
- Abboud Kirellos
- Abdallah Ahmed
- Abdalsalam Sabriya Juma Ali
- Abdelaal Abdelrahman
- Abdelalemm Mohamed
- Abdelhafez Mohammed Hisham Zayan
- Abdelhalim Karim
- Abdeljalil Mahmoud
- Abdelkarem Mohamed
- Abdelmageed Abdelfatah
- Abdelmageed Abdelfatah
- Abdelmaksoud Mohamed
- Abdelmawgoud Sherif
- Abdelmawla Mohamed
- Abdelmawla Mohamed Osama Mohammed Kamel
- Abdelmoneim Noha
- Abdelnoor Ahmad
- Abdelrahman Fatma
- Abdelrazek Hussein A
- Abdelrhman Reham
- Abdelzaher Abdurrahman
- Abdelzaher Abdurrahman Taha
- Abdou Khaled
- Abdoun Meriem
- Abdualqader Mahmmoud
- Abdualqader Mahmmoud Yehia Mohammed
- Abdulhaq Aram
- Abduljawad Heba
- Abdullaev Abakar
- Abdullah Nik Azim Nik
- Abdulmonem Aya
- Abdulwahed Eman
- Abebrese John
- Abiyere Henry
- Abobakr Abobakr Mahfoz
- Aboelfath Shiamaa
- Abosamak Nour Eldin
- Abu-Elfatth Ahmed Mohammed
- Abu-Ghazal Sara
- Abu-Ghazal Sara Yassir
- Abuali Ahmed S A M E
- Abuelazm Mohamed
- Abuelnaga Yasmeen
- Abuelnaga Yasmeen
- Abughazal Sara Yasser
- Abuleil Amro
- Abusannuga Malek
- Abuzaina Khalil
- Adam Islam
- Aday Ulaş
- Adeyeye Ademola
- Adeyeye Nigeria Ademola
- Adham Mustapha
- Adhikari Krishna Mohan
- Affary Anter Al
- Afzal Ameer
- Afzal Iqraa
- Aghdassi Ali
- Ahmed Emad Ali
- Ahmed Mohamed Bahaa Eldin
- Ahmed Randa
- Ahmeed Sultan
- Ajayi Peter
- Akahoshi Keiichi
- Akbar Ali
- Akhtar Naseem
- Al-Abdi Radfan
- Al-Abed Omar
- Al-Ameri Saba
- Al-Ameri Saba Ahmed Ahmed Saleh
- Al-Asadi Mohammed Abdulkhaleq Mohammed Mohsen
- Al-Dowsh Nagra Are
- Al-Eryani Fatima
- Al-Faiq Siham
- Al-Haj Ahmad
- Al-Hyari Abdelkareem
- Al-Isawi Ali
- Al-juaifari Maytham Aqeel
- Al-Khawlani Qaeid
- Al-Kubati Waheeb
- Al-Maadani Basma
- Al-Mallah Rozana
- Al-Markiz Eman
- Al-Mekhlafi Ayat
- Al-Melhani Watheeq
- Al-Naggar Hamza
- Al-Naggar Hamza
- Al-Ogaili Mustafa
- Al-Qasrawi Shahd
- Al-Saban Rafat
- Al-saban Rafat Ameen Mohammed
- Al-Sader Maytham Al-Juaifari
- Al-Samawi Abdulaziz
- Al-Samawi Hytham
- Al-Sarireh Bilal
- Al-Shami Khayry
- Al-shami Manar
- Al-sharabi Ebrahim Ahmed Esmail
- Al-Shehari Mohammed
- Al-Tekreeti Sarah
- Alahmed Farouq
- Alahmed Hoor
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- Alali Mahmoud Bilal
- Alannaz Omar
- Alansary Marwa Nasrelden
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- Alattas Zainab
- Alawna Reem
- Alazab Emad
- Albaba Safa'
- Albakry Rudaina
- Albar Aisha
- Albaraesi Mohammed N
- Albarouni Sofian
- Albishti Ahmed
- Alboridy Muneera
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- Oldani Graziano
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- S Induchoodan P
- Saa'd Hussam
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- Saad Ahmed Saeed
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- Salah Mohamed
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- Sergeant Gregory
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- Shaaban Ammar Magdy
- Shaat Mohamed M
- Shaban Mahmoud
- Shafqatullah Syed
- Shah Kalpesh
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- Shamakhi Taha Mahmoud Omar
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- Shcherba Aliaksei
- Shcherba Aliaksei
- Sheen Professor Aali
- Shehta Ahmed
- Shenawi Hamdi Al
- Sheshe Abdulrahaman Abba
- Shinde R M
- Shingler Guy
- Shokralla Shaher
- Shoukrie Shoukrie
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- Shream Sarah Abdulkhaliq Ali
- Shrikhande Shailesh V
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- Shumrakh Saeed K
- Shwely Farah Al
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- Spanu Andrada
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- Sritharan Mithra
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- Suhaimi Nurul Ain Batrisyia
- Sulaiman Abdallah S
- Sulciner Megan
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- Sulpice Laurent
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- Tamburrino Domenico
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- Tammik Olav
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- Tinguely Pascale
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- Torelly Lucas
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- Torres Orlando
- Torres Orlando Jorge M
- Torres Silvio Melo
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- Toso Christian
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- TrotovŠek Blaž
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- Ullah Sami
- Unalp Omer Vedat
- Urciuoli Irene
- Uzir Sofia Suhda Binti Mohd
- Uzunoglu Faik G
- Vaccara Vincenzo La
- Vaia Aliki
- Vailas Michail
- Vaishnav Dhaivat
- Val Alejandro Ramirez-Del
- Valaroutsos Alexandros
- Valcarcel Ana Quiroga
- Valente Roberto
- Valeriia Sumarokova
- Valladares Andre Moguel
- Valmorisco Marcos Alba
- Valverde David Padilla
- Van Dam Jacob L
- Van den Bossche Bert
- van Eijck Casper HJ
- van Laarhoven Stijn
- Vanagas Tomas
- Varshney Vaibhav
- Vasavada Bhavin
- Vaslamatzis Michalis
- Vass David
- Vassiliu Pantelis
- Vazquez Pedro Gil
- Velagala Jayapala Reddy
- Velagala Jayapala Reddy
- Velázquez Patricia Sánchez
- Velenciuc Natalia
- Veneroni Luigi
- Venkatesh N R
- Vennarecci Giovanni
- Vera Valle
- Vereczkei Andras
- Vezakis Antonios
- Vigia Emanuel
- Vilcu Mihaela
- Vilhav Caroline
- Vincenti Leonardo
- Virk Sargun
- Vishnoi Jeewan Ram
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- Vladov Nikola
- Vodyala Charishma
- Vougas Vasileios
- Vouros Dimitrios
- Vrakopoulou Gavriella Zoi
- Waechter Fábio Luiz
- Waffa Zuraiha
- Wagner Ki
- Wahib El Mahdi
- Wake Rudyard
- Wang Huaizhi
- Wang Jiping
- Waqar Usama
- Waqar Usama
- Wardeh Salah
- Wardeszkiewicz Aleksander
- Wassmer Charles-Henri
- Weber Markus
- Wei Alice
- Wei Kongyuan
- Wei Kongyuan
- Weitz Jürgen
- Wellner Ulrich
- Welsch Thilo
- Welsh Fraser
- Wen Daniel
- Wennerblom Johanna Hansson
- Wenning Anna Silvia
- Wicherts Dennis
- Wierzchowski Michał
- Wikar Tomasz
- Williamsson Caroline
- Windsor John
- Winslow Emily
- Wlazlak Michal
- Wolfgang Christopher
- Wu Chien Hui
- Wu Chien Hui
- Wüllenweber Hans-Peter
- Wyroślak-Najs Justyna
- Yadav Kaushal
- Yadev Induprabha
- Yadev Induprabha
- Yaghan Rami
- Yamamoto Tomohisa
- Yang Po-Chih
- Yassin Laya Moayyad Ahmed
- Yassin Raya
- Yegen Cumhur
- Yeo Charles
- Yesilyurt Degercan
- Yip Vincent
- Yoong Boon
- Yoong Boon Koon
- Younes Eman
- Younes Eman
- Young Alistair
- Yousef Amal
- Youssef Amal
- Yu Ming-Chin
- Zacharakis Emmanouil
- Zacharoulis Dimitrios
- Zachiotis Marinos
- Zagainov Vladimir
- Zaharie Florin
- Zahed Mohamed
- Zahed Mohamed Samir Mohamed
- Zakaria Andee Dzulkarnaen
- Zamri Fatimah Mardhiyyah Binti
- Zanatta Michela
- Zanello Matteo
- Zanini Nicola
- Zanus Giacomo
- Zanus Giacomo
- Zaruba Pavel
- Zawia Ali
- Zayed Ahmed
- Zdujic Predrag
- Zedelj Jurica
- Zeh Herbert J
- Zentar Aziz
- Zerbi Alessandro
- Zidan Taha
- Zidan Taha
- Zironda Andrea
- Zitawi Abdullah
- Zivanovic Marko
- Zogopoulos George
- Zonta Sandro
- Zonta Sandro
- Zorrilla Carlos Florez
- Zozaya Gabriel
- Zreqat Qusai
- Zuhdi Zamri
- Zuhdy Mohammad
- Zygomalas Apollon
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide.Methods: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters.Results: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 percent of patients (2901 of 4223). Major complication rates (Clavien-Dindo grade at least IIIa) were 24, 18, and 27 percent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 percent; however, it was 41 per cent in low-to-middle-compared with 19 per cent in very high-HDI countries.Conclusion: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761)
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
- Ayyad Rawan
- Azevedo José
- Azodo Ijeoma
- Azzubia Joma
- B L Ashika
- Ba Mouhamadou Bachir
- Babaa Basheer
- Babirye Lilian
- Bacic Ivan
- Badr Esraa Tarek
- Badr Helmy
- Badran Abdul
- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
- Bajilan Mohammad
- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
- Bakoleas Panagiotis
- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
- Bamaca Ixcajoc Elvis Benjamin
- Banaz Tuba
- Banda Bitiel
- Banglani Muntaha
- Bani Hani Farah
- Bani hani Mohammad
- Bani hani Zeina
- Baniowda Muath
- Banks Alexander
- Bannister Sharon
- Baranyai Zsolt
- Barati Nastaran
- Barbosa Camacho Francisco José
- Barbosa José
- Bardos David
- Barendegere Venerand
- Barghuthi Lutfi
- Barhoush Ola
- Barnes Nicole
- Baronio Gianluca
- Barreda Zelaya Lilian Elizabeth
- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
- Bartosiak Katarzyna
- Basarab Maksym
- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
- Bath Michael
- Beattie Miriam
- Bedada Alemayehu Ginbo
- Belais Fanny
- Belal qadomi Asef
- Belev Nikolay
- Belli Andrea
- Beltrán de Heredia Juan
- Belvedere Angela
- Ben Dallah Najah
- Ben Saoud Abdulsalam Ali
- Bengur Fuat Baris
- Benkabbou Amine
- Benke Marton
- Benyaiche Chaymae
- Bergeat Damien
- Bernstein Mitchell
- Beshtawi Doha
- Besli Sevval
- Beuran Mircea
- Bhandare Manish
- Bhangu Aneel
- Bhatti Muhammad Iqbal
- Bianchini Stefania
- Bianco Francesco
- Bibas Fatma
- Biccard Bruce M
- Bielosludtsev Oleksii
- Bienfait Mumbere
- Billy Matthew
- Bin Mohamad Sithik Muhammad Navid
- Binetti Margherita
- Bingham Janne
- Bird Jonathan
- Birindelli Arianna
- Birks Sarah
- Birutis Justas
- Björklund Ida
- Blackman Brighid
- Blackwell James
- Blanco-Colino Ruth
- Blok Robin
- Blomme Nina
- Blomqvist Malin
- Blunnie Eimear
- Bnhameida Sondos
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- Forero-Torres Alexander
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- Foschi Diego
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- Hall Timothy
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- Hassabalnaby Mohamed
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- Zaffaroni Gloria
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- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
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- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
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- Alasttal Mohammed
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- Albaggar Marwa
- Albahnasawi Moath A.
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- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
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- Almasri Murad
- Almeida Braga Sara
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- Almigheerbi Alabas
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- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
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- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
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- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
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- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
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- Andreotti Dario
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- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
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- Appukuttan Akhila
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- Archibald Jess
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- Argudo Nuria
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- Arizpe Daniel
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- Athamneh Sarah
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- Atkociunas Aivaras
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- Au Angela
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- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
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- Aytac Erman
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- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
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- Bake Jacques
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- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
- Bartosiak Katarzyna
- Basarab Maksym
- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
- Bath Michael
- Beattie Miriam
- Bedada Alemayehu Ginbo
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- Bianco Francesco
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- Woon-Shoo-Tong Xiao-Ming Sarah
- Wren Sherry
- Wuraola Funmilola
- Xanthopoulou Georgia
- Yabut Kenneth
- Yacoub Aseel
- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
- Yalçinkaya Ali
- Yang P Zichu
- Yanikoğlu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürşat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
- Yepez Raul
- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
- Ylatoma Díaz Edgar Alcides
- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
- Younes Eman
- Younes Maha
- Yousry Basant
- Yozgatli Tahir Koray
- Yu Kristin
- Yue Sum Yu Pansy
- Yunes Asmaa
- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research