What is …?: a research ethics jeopardy" game to help community partners understand human subjects protections and their importance.

Although community partners in participatory research need to understand basic principles of research ethics and human subjects protections, few tools have been designed with these partners in mind. To assist in this process, and help engage youth community partners in learning this critical material, a game was developed based on the popular television program Jeopardy(TM). Piloted with a group of 18 Mexican- American adolescents as part of a broader community-based participatory research(CBPR) project, the game begins with small group study of infamous cases of research ethics violations (eg. the Tuskegee Syphilis Study) and of the human subjects protections that resulted. The participants then play the Jeopardy game in teams, responding to “What is . . . ?” questions concerning the five infamous research studies and corresponding human subjects protections. Although observational findings revealed substantial learning and active engagement in the process, as well as strong retention of the material several months later, the tool requires further evaluation. Based on this pilot experience, however, we believe the Research Ethics Jeopardy™ Game offers promise in helping youth and other community partners in CBPR master critical information about human subjects protections and their importance in an accessible and lively manner

The influence of regional location on the innovation activity of Spanish firms: A logit analysis.

The set of elements which explain the results of the innovation process undertaken by the firms is an ongoing cause of worry for policy makers. In our case, after analyzing how R+D activities and their results are related to regional development, we will examine the factors which influence investigation activities. Among this factors we shall include both those related to the characteristics of the companies as well as government funding of R+D or the effects of the firms' location. In order to do this a logit model will be created in which the endogenous variable will measure whether or not an enterprise has patented an innovative activity. The final objective of the paper is to provide policy makers with a way of evaluating the results of their policies, as well as to examine the effects of other elements in the process. Keywords: R+D, Regional Development, Technological Policy, Patents.

Nematic phase in the J1_1-J2_2 square lattice Ising model in an external field

The J$_1$-J$_2$ Ising model in the square lattice in the presence of an external field is studied by two approaches: the Cluster Variation Method (CVM) and Monte Carlo simulations. The use of the CVM in the square approximation leads to the presence of a new equilibrium phase, not previously reported for this model: an Ising-nematic phase, which shows orientational order but not positional order, between the known stripes and disordered phases. Suitable order parameters are defined and the phase diagram of the model is obtained. Monte Carlo simulations are in qualitative agreement with the CVM results, giving support to the presence of the new Ising-nematic phase. Phase diagrams in the temperature-external field plane are obtained for selected values of the parameter $\kappa=J_2/|J_1|$ which measures the relative strength of the competing interactions. From the CVM in the square approximation we obtain a line of second order transitions between the disordered and nematic phases, while the nematic-stripes phase transitions are found to be of first order. The Monte Carlo results suggest a line of second order nematic-disordered phase transitions in agreement with the CVM results. Regarding the stripes-nematic transitions, the present Monte Carlo results are not precise enough to reach definite conclusions about the nature of the transitions.Comment: 13 pages, 10 figure

Rawls y el republicanismo: sobre la cuestión del carácter liberal del proyecto político rawlsiano

La interpretación que cuestiona el carácter efectivamente “liberal” del pensamiento de Rawls se sostendrá en la tesis que considera que, en el presumible “giro político” de Political Liberalism, al abordar la cuestión de la estabilidad, el filósofo recurriría a algunos elementos centrales del Neorepublicanismo. Esta lectura, no obstante, contrastará con la identificación de algunos de estos conceptos ya en los primeros bosquejos de su teoría de la justicia, presencia que, desde una lectura genérica, aparecerá como una constante del rawlsismo, originada básicamente por la relación que el autor establece con las diversas fuentes filosóficas presentes en el desarrollo de su propuesta

Ventajas y desventajas del comercio electrónico para la industria aeronáutica en Colombia

El presente ensayo está estructurado en principio, a reconocer el campo histórico que dio lugar al comercio en línea, todos aquellos sucesos previos a lo que hoy en día conocemos como e-commerce, así mismo, la compilación de aquellas ventajas y desventajas que han sido abordadas por autores en sus trabajos sobre el tema, pero más allá de esta recopilación de información, esta la relación entre el comercio en línea y el comercio aeronáutico, sus incidencias en el desarrollo de la industria, sus pros y sus contras, considerando así, el impacto social, económico, laboral de este fenómeno y su relación con otras herramientas de comercio internacional como los tratados de libre comercio, más exactamente el TLC entre Colombia y Estados Unidos, que permita conjeturar si en realidad dicha herramienta abre las puertas de la nación a un desarrollo de la nación en términos de industria aeronáutica o si por el contrario da desarrollo de la nación en términos de comercio

Toma de decisiones

Este ensayo permite al lector conocer acerca de algunas crisis financieras importantes, que sucedieron en el mundo con sus consecuencias. Así mismo, podrá analizar y entender las decisiones que se tomaron en el momento en el que se presentaron estas. Para ello, es importante tener el juicio del por qué el sector financiero, a nivel mundial, colapsó en algunos periodos de tiempo. Adicional, le permitirá conocer el punto de vista de personas expertas, frente a algunas estrategias que se pueden tomar si se presenta alguna dificultad

Elucidating the role of a basic helix loop helix (bHLH) transcription factor (TF) during bud break in hybrid aspen.

openIn extreme weather conditions, perennial trees have developed mechanisms that help them to survive these environmental cues. Temperature and day length regulates the bud burst in Aspen in the spring. The molecular basis of basic helix loop helix (bHLH) transcription factors mediated control of bud break is poorly understood. Here we identify and elucidate a transcription factor involved in the control of bud break in hybrid aspen. The transcription factor T89CIB is closely related to Arabidopsis Floral inducer AtCIB1 acting, activating, and regulated in a similar manner as we can infer until now. To understand where is localized, how it is regulated, and the effect on bud break. Two constructs 35S: T89CIB and 35S: AtCIB1 were made, and subcellular localization of the transcription factors was performed by Confocal Laser Scanning Microscopy. Furthermore, to explain the regulation of the proteins, Nicotiana benthamiana plants were infiltrated and exposed under dark and blue light conditions, finally, COL-O and cry2 lines were transformed with T89 CIB using Floral dip as a transformation method in Arabidopsis Thaliana. We elucidate the nuclear localization and demonstrate the role of blue light and dark as positive and negative regulators respectively. And the possible interaction and phenotype of T89CIB and Cryptochrome 2 (CRY2). Thus, our results reveal the basis of the T89CIB transcription factor and support the idea of the importance of this protein as part of the pathways activated during bud break in Hybrid Aspen. Elucidating these pathways will give a better understanding of the survival of Perennial trees under harsh conditions.In extreme weather conditions, perennial trees have developed mechanisms that help them to survive these environmental cues. Temperature and day length regulates the bud burst in Aspen in the spring. The molecular basis of basic helix loop helix (bHLH) transcription factors mediated control of bud break is poorly understood. Here we identify and elucidate a transcription factor involved in the control of bud break in hybrid aspen. The transcription factor T89CIB is closely related to Arabidopsis Floral inducer AtCIB1 acting, activating, and regulated in a similar manner as we can infer until now. To understand where is localized, how it is regulated, and the effect on bud break. Two constructs 35S: T89CIB and 35S: AtCIB1 were made, and subcellular localization of the transcription factors was performed by Confocal Laser Scanning Microscopy. Furthermore, to explain the regulation of the proteins, Nicotiana benthamiana plants were infiltrated and exposed under dark and blue light conditions, finally, COL-O and cry2 lines were transformed with T89 CIB using Floral dip as a transformation method in Arabidopsis Thaliana. We elucidate the nuclear localization and demonstrate the role of blue light and dark as positive and negative regulators respectively. And the possible interaction and phenotype of T89CIB and Cryptochrome 2 (CRY2). Thus, our results reveal the basis of the T89CIB transcription factor and support the idea of the importance of this protein as part of the pathways activated during bud break in Hybrid Aspen. Elucidating these pathways will give a better understanding of the survival of Perennial trees under harsh conditions

Linear combination of information in time series analysis

An important tool in time series analysis is that of combining information in an optimal manner. Here we establish a basic combining rule of linear estimators and exemplify its use with several different problems faced by a time series analyst. A compatibility test statistic is also provided as a companion of the combining rule. This statistic plays a fundamental role for obtaining sensible results from the combination and for pointing out sorne possibly new directions of analysis

Towards the cloudification of the social networks analytics

In the last years, with the increase of the available data from social networks and the rise of big data technologies, social data has emerged as one of the most profitable market for companies to increase their benefits. Besides, social computation scientists see such data as a vast ocean of information to study modern human societies. Nowadays, enterprises and researchers are developing their own mining tools in house, or they are outsourcing their social media mining needs to specialised companies with its consequent economical cost. In this paper, we present the first cloud computing service to facilitate the deployment of social media analytics applications to allow data practitioners to use social mining tools as a service. The main advantage of this service is the possibility to run different queries at the same time and combine their results in real time. Additionally, we also introduce twearch, a prototype to develop twitter mining algorithms as services in the cloud.Peer ReviewedPostprint (author’s final draft