315 research outputs found

    Cracking of coated materials under transient thermal stresses

    Get PDF
    The crack problem for a relatively thin layer bonded to a very thick substrate under thermal shock conditions is considered. The effect of surface cooling rate is studied by assuming the temperature boundary condition to be a ramp function. Among the crack geometries considered are the edge crack in the coating layer, the broken layer, the edge crack going through the interface, the undercoat crack in the substrate and the embedded crack crossing the interface. The primary calculated quantity is the stress intensity factor at various singular points and the main variables are the relative sizes and locations of cracks, the time, and the duration of the cooling ramp. The problem is solved and rather extensive results are given for two material pairs, namely a stainless steel layer welded on a ferritic medium and a ceramic coating on a steel substrate

    CD44 Staining of Cancer Stem-Like Cells Is Influenced by Down-Regulation of CD44 Variant Isoforms and Up-Regulation of the Standard CD44 Isoform in the Population of Cells That Have Undergone Epithelial-to-Mesenchymal Transition

    Get PDF
    PMCID: PMC3577706This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

    The mode 3 crack problem in bonded materials with a nonhomogeneous interfacial zone

    Get PDF
    The mode 3 crack problem for two bonded homogeneous half planes was considered. The interfacial zone was modelled by a nonhomogeneous strip in such a way that the shear modulus is a continuous function throughout the composite medium and has discontinuous derivatives along the boundaries of the interfacial zone. The problem was formulated for cracks perpendicular to the nominal interface and was solved for various crack locations in and around the interfacial region. The asymptotic stress field near the tip of a crack terminating at an interface was examined and it was shown that, unlike the corresponding stress field in piecewise homogeneous materials, in this case the stresses have the standard square root singularity and their angular variation was identical to that of a crack in a homogeneous medium. With application to the subcritical crack growth process in mind, the results given include mostly the stress intensity factors for some typical crack geometries and various material combinations

    Determination of the Heat Distribution in the Raw Cotton Packed in the Coil

    Get PDF
    As a result of experimental studies, a special mathematical model of raw cotton is developed. The effect of density change on the thermal conductivity coefficient is determined. A nonlinear differential equation of heat propagation in coils is obtained. The dependence of the density of raw cotton on the coil height is determined experimentally. The heat flux is intense propagating from denser layers of raw cotton to less dense ones. In a saturated form, the effect of density changes on the propagation of heat is less than in the coils. Pocket spontaneous heating occurs locally with sharp boundaries.An expression is found, which is the general solution of the mathematical model of heat propagation in raw cotton in coils, on the basis of which a number of physical real models can be constructed.The model allows to preliminarily give an estimation of the likely picture of the temperature field in the given microvolumes of raw cotton

    The crack problem in bonded nonhomogeneous materials

    Get PDF
    The plane elasticity problem for two bonded half planes containing a crack perpendicular to the interface was considered. The effect of very steep variations in the material properties near the diffusion plane on the singular behavior of the stresses and stress intensity factors were studied. The two materials were thus, assumed to have the shear moduli mu(o) and mu(o) exp (Beta x), x=0 being the diffusion plane. Of particular interest was the examination of the nature of stress singularity near a crack tip terminating at the interface where the shear modulus has a discontinuous derivative. The results show that, unlike the crack problem in piecewise homogeneous materials for which the singularity is of the form r/alpha, 0 less than alpha less than 1, in this problem the stresses have a standard square-root singularity regardless of the location of the crack tip. The nonhomogeneity constant Beta has, however, considerable influence on the stress intensity factors

    AGGREGATE STABILITY AND WATER RETENTION NEAR SATURATION CHARACTERISTICS AS AFFECTED BY SOIL TEXTURE, AGGREGATE SIZE AND POLYACRYLAMIDE APPLICATION

    Get PDF
    Understanding the effects of soil intrinsic properties and extrinsic conditions on aggregate stability is essential for the development of effective soil and water conservation practices. Our objective was to evaluate the combined role of soil texture, aggregate size and application of a stabilizing agent on aggregate and structure stability indices (composite structure index [SI], the and n parameters of the VG model and the S-index) by employing the high energy (0-5.0 J kg(-1)) moisture characteristic (HEMC) method. We used aggregates of three sizes (0.25-0.5, 0.5-1.0 and 1.0-2.0 mm) from four semi-arid soils treated with polyacrylamide (PAM). An increase in SI was associated with the increase in clay content, aggregate size and PAM application. The value of increased with the increase in aggregate size and with PAM application but was not affected by soil texture. For each aggregate size, a unique exponential type relationship existed between SI and . The value of n and the S-index tended, generally, to decrease with the increase in PAM application; however, an increase in aggregate size had an inconsistent effect on these two indices. The relationship between SI and n or the S-index could not be generalized. Our results suggest that (i) the effects of PAM on aggregate stability are not trivial, and its application as a soil conservation tool should consider field soil condition, and (ii), n and S-index cannot replace the SI as a solid measure for aggregate stability and soil structure firmness when assessing soil conservation practices

    Cracking of a layered medium on an elastic foundation under thermal shock

    Get PDF
    The cladded pressure vessel under thermal shock conditions which is simulated by using two simpler models was studied. The first model (Model 1) assumes that, if the crack size is very small compared to the vessel thickness, the problem can be treated as a semi-infinite elastic medium bonded to a very thin layer of different material. However, if the crack size is of the same order as the vessel thickness, the curvature effects may not be negligible. In this case it is assumed that the relatively thin walled hollow cylinder with cladding can be treated as a composite beam on an elastic foundation (Model 2). In both models, the effect of surface cooling rate is studied by assuming the temperature boundary condition to be a ramp function. The calculated results include the transient temperature, thermal stresses in the uncracked medium and stress intensity factors which are presented as a function of time, and the duration of cooling ramp. The stress intensity factors are also presented as a function of the size and the location of the crack. The problem is solved for two bonded materials of different thermal and mechanical properties. The mathematical formulation results in two singular integral equations which are solved numerically. The results are given for two material pairs, namely an austenitic steel layer welded on a ferritic steel substrate, and a ceramic coating on ferritic steel. In the case of the yielded clad, the stress intensity factors for a crack under the clad are determined by using a plastic strip model and are compared with elastic clad results

    Critical review of interventions against Salmonella in the farm-to-processing pork production continuum

    Get PDF
    The purpose of this study was to identify, evaluate and summarize the available scientific literature on the effectiveness of interventions against Salmonella, in the farm-to-processing pork production continuum, following the principles of systematic review methodology

    An Agent-based Simulator for the Gastrointestinal Pathway of Listeria monocytogenes

    Get PDF
    We developed an agent-based gastric simulator for a human host to illustrate the within host survival mechanisms of Listeria monocytogenes. The simulator incorporates the gastric physiology and digestion processes that are critical for pathogen survival in the stomach. Mathematical formulations for the pH dynamics, stomach emptying time, and survival probability in the presence of gastric acid are integrated in the simulator to evaluate the portion of ingested bacteria that survives in the stomach and reaches the small intestine. The parameters are estimated using in vitro data relevant to the human stomach and L. monocytogenes. The simulator predicts that 5%–29% of ingested bacteria can survive a human stomach and reach the small intestine. In the absence of extensive scientific experiments, which are not feasible on the grounds of ethical and safety concerns, this simulator may provide a supplementary tool to evaluate pathogen survival and subsequent infection, especially with regards to the ingestion of small doses

    Modeling Cross-Contamination During Poultry Processing: Dynamics in The Chiller Tank

    Get PDF
    Understanding mechanisms of cross-contamination during poultry processing is vital for effective pathogen control. As an initial step toward this goal, we develop a mathematical model of the chilling process in a typical high speed Canadian processing plant. An important attribute of our model is that it provides quantifiable links between processing control parameters and microbial levels, simplifying the complexity of these relationships for implementation into risk assessment models. We apply our model to generic, non-pathogenic Escherichia coli contamination on broiler carcasses, connecting microbial control with chlorine sanitization, organic load in the water, and pre-chiller E. coli levels on broiler carcasses. In particular, our results suggest that while chlorine control is important for reducing E. coli levels during chilling, it plays a less significant role in the management of cross-contamination issues
    • …
    corecore