118 research outputs found
Le potentiel touristique du RAVeL en Wallonie
* Mise en évidence des rôles touristiques et de loisirs des voies vertes, et
compréhension des attentes des utilisateurs quant à celles-ci.
* Mise en évidence de tronçons RAVeL pouvant être supports d’activités touristiques par
méthodes géomatiques.
* Analyse de corrélations entre les fréquentations des RAVeL et ses caractéristiques
environnementales : discussion.
* Implication : poursuivre la stratégie de développement et la récolte de données
statistiques
Comparison of analytical performances between clot waveform analysis and FibWave in edoxaban-treated patients and healthy controls
The activated partial thromboplastin time (aPTT) and the prothrombin time (PT) are widely available coagulation parameters which are however poor predictors of the anticoagulant effect of direct oral anticoagulants (DOACs). Some coagulometers use the clot waveform analysis (CWA) to assess the clotting time but mainly based on a unique parameter. The improvement of these methodologies and the evaluation of the other waveform parameters may increase the sensitivity to DOACs. To assess the performance of an improved clot waveform an method (i.e. FibWave) to detect the impact of edoxaban on the coagulation and the fibrinolytic systems. Seventy-one samples from patients treated with edoxaban collected at minimum concentration (C) and/or maximum concentration (C), and 45 control samples were included. The aPTT- and PT-based CWA as well as the FibIn, FibEx, and FibLysis methodologies of the FibWave were implemented and performed on an ACL-TOP 700. PT and FibEx clotting time were strongly correlated to edoxaban concentration (Pearson = 0.80 and 0.89, respectively). The FibEx clotting time allowed a better discrimination for samples with 30 and 50 ng/ml of edoxaban compared to PT (cutoffs of 96.5 and 114.2 s for the FibEx versus a unique cutoff of 13.1 s for the PT). The fibrinolytic process was impaired in the presence of edoxaban in a dose-dependent manner. FibEx is more sensitive than aPTT- and PT-based CWA for the detection of the clinically relevant anticoagulant level of edoxaban
Parietal fibrinous peritonitis in cattle: A literature review
peer reviewedBackground: Parietal fibrinous peritonitis (PFP) is a complication of laparotomy
in cattle, consisting of fluid and fibrin accumulation within a fibrous
capsule between the parietal peritoneum and the abdominal muscles. Since
scientific information on PFP is scarce, we aim to collect available information
to help practitioners in its diagnosis and treatment, and to formulate
research perspectives.
Methods: PubMed and GoogleScholar databases were scanned using “cattle”
or “bovine”, and one of the following keywords: “seroma”, “parietal fibrinous
peritonitis”, “retroperitoneal abscess”, or “wound infection”.
Results: Although scientific information is often anecdotal, two recent larger
studies shed more light on PFP symptoms, diagnosis and treatment. Symptoms
vary according to the cavity’s localisation and size, and include anorexia,
weight loss and an inflammatory status. Rectal palpation is strongly indicative,
but the definitive diagnosis is made by ultrasound. Trueperella pyogenes
and Escherichia coli are frequently isolated germs, although it remains
unclear whether they are primary or secondary agents. Good survival rates
were reported after surgical drainage.
Conclusion: Although the diagnosis and treatment seem clear, the exact
pathogenesis of PFP should be the focus of ongoing research. This can be
achieved by epidemiological data analysis focusing on risk factors like surgery
technique, housing and ration
How AGN feedback and metal cooling shape cluster entropy profiles
Observed clusters of galaxies essentially come in two flavors: non cool core
clusters characterized by an isothermal temperature profile and a central
entropy floor, and cool-core clusters where temperature and entropy in the
central region are increasing with radius. Using cosmological resimulations of
a galaxy cluster, we study the evolution of its intracluster medium (ICM) gas
properties, and through them we assess the effect of different (sub-grid)
modelling of the physical processes at play, namely gas cooling, star
formation, feedback from supernovae and active galactic nuclei (AGN). More
specifically we show that AGN feedback plays a major role in the pre-heating of
the proto-cluster as it prevents a high concentration of mass from collecting
in the center of the future galaxy cluster at early times. However, AGN
activity during the cluster's later evolution is also required to regulate the
mass flow into its core and prevent runaway star formation in the central
galaxy. Whereas the energy deposited by supernovae alone is insufficient to
prevent an overcooling catastrophe, supernovae are responsible for spreading a
large amount of metals at high redshift, enhancing the cooling efficiency of
the ICM gas. As the AGN energy release depends on the accretion rate of gas
onto its central black hole engine, the AGN responds to this supernova enhanced
gas accretion by injecting more energy into the surrounding gas, and as a
result increases the amount of early pre-heating. We demonstrate that the
interaction between an AGN jet and the ICM gas that regulates the growth of the
AGN's BH, can naturally produce cool core clusters if we neglect metals.
However, as soon as metals are allowed to contribute to the radiative cooling,
only the non cool core solution is produced.Comment: 19 pages, 13 figures, accepted for publication in MNRA
Antimicrobial Susceptibility Profile of Several Bacteria Species Identified in the Peritoneal Exudate of Cows Affected by Parietal Fibrinous Peritonitis after Caesarean Section
peer reviewedAbstract: The aim of this study was to identify the species and antimicrobial susceptibility of
bacteria involved in parietal fibrinous peritonitis (PFP).We studied 156 peritoneal fluid samples from
cows presenting PFP after caesarean section. Bacteria were cultured in selective media and their
antimicrobial susceptibility was tested by disk diffusion assay. Bacteria were isolated in the majority
(129/156; 83%) of samples. The majority (82/129; 63%) of positive samples contained one dominant
species, while two or more species were cultured in 47/129 (36%) samples. Trueperella pyogenes (T.
Pyogenes) (107 strains) was the most identified species, followed by Escherichia coli (E. coli) (38 strains),
Proteus mirabilis (P. mirabilis) (6 strains), and Clostridium perfringens (C. perfringens) (6 strains). Several
other species were sporadically identified. Antimicrobial susceptibility was tested in 59/185 strains,
predominantly E. coli (38 strains) and P. mirabilis (6 strains). Antibiotic resistance, including resistance
to molecules of critical importance, was commonly observed; strains were classified as weakly drug
resistant (22/59; 37%), multidrug resistant (24/59; 41%), extensively drug resistant (12/59; 20%), or
pan-drug resistant (1/59; 2%). In conclusion, extensive antibiotic resistance in the isolated germs
might contribute to treatment failure. Ideally, antimicrobial therapy of PFP should be based upon
bacterial culture and susceptibility testing
MoMaF : The Mock Map Facility
We present the Mock Map Facility, a powerful tool to generate mock catalogues
or images from semi-analytically post-processed snapshots of cosmological
N-body simulations. The paper describes in detail an efficient technique to
create such mocks from the GALICS semi-analytic model, providing the reader
with an accurate quantification of the artifacts it introduces at every step.
We show that replication effects introduce a negative bias on the clustering
signal -- typically peaking at less than 10 percent around the correlation
length. We also thoroughly discuss how the clustering signal is affected by
finite volume effects, and show that it vanishes at scales larger than about a
tenth of the simulation box size. For the purpose of analysing our method, we
show that number counts and redshift distributions obtained with GALICS and
MOMAF compare well to K-band observations and to the 2dFGRS. Given finite
volume effects, we also show that the model can reproduce the APM angular
correlation function. The MOMAF results discussed here are made publicly
available to the astronomical community through a public database. Moreover, a
user-friendly Web interface (http://galics.iap.fr) allows any user to recover
her/his own favourite galaxy samples through simple SQL queries. The
flexibility of this tool should permit a variety of uses ranging from extensive
comparisons between real observations and those predicted by hierarchical
models of galaxy formation, to the preparation of observing strategies for deep
surveys and tests of data processing pipelines.Comment: 19 pages, 15 Figs, significantly modified version now accepted for
publication in MNRAS. High-resolution version available at
http://galics.cosmologie.fr/papers/momaf.ps.g
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