311 research outputs found
Health-promoting places in the growing city : a design proposal for SĂ€vja churchâs outdoor environment with a focus on mental recovery and stress reduction
Dagens samhÀlle vÀxer konstant och urbaniseringen sker i allt högre grad. Exploatering och förtÀtning anses vara en naturlig del av samhÀllsutvecklingen och kan i teorin generera en god livsmiljö. DÀremot medför fenomenet Àven en ökad mental belastning och stress pÄ grund av det höga tempot inne i stÀderna i kombination med stora flöden av nya intryck samt brist pÄ tid för ÄterhÀmtning.
I linje med att stÀderna expanderar tas rekreationsomrÄden i ansprÄk för bebyggelse och avstÄndet till naturen ökar dÄ stadsgrÀnser vidgas. Detta ger upphov till att mÄnga invÄnare inte finner tid till att spendera tid i naturen vilken forskning anser Àr vÀsentligt för att sÀkerstÀlla en god folkhÀlsa i de vÀxande stÀderna.
Bristen pÄ bostadsnÀra grönytor i exploaterande stadsdelar Àr ytterst relevant för nutidens verksamma landskapsarkitekter. Dilemmat vÀcker funderingar kring hur det Àr möjligt att öka tillgÄngen pÄ grönytor för att sÀkerstÀlla en hÄllbar utveckling av framtidens stÀder.
SÀvja kyrka, i sydöstra Uppsala, omges av 0,6 hektar naturmark som i dagslÀget upplevs otillgÀnglig och outnyttjad. Sydöstra Uppsala stÄr inför en större exploatering vilket gör detta till ett fall dÀr kvaliteten pÄ de existerande grönomrÄdena bör vara en prioritering. Genom ett gestaltningsförslag för SÀvja kyrkas utomhusmiljö, som avser att frÀmja ÄterhÀmtning och stressreducering, kan en större mÄlgrupp ta del av naturen. Förslaget utgör uppsatsens resultat och Àmnar göra SÀvja kyrkas utomhusmiljö till en hÀlsofrÀmjande plats som riktar sig till kyrkans besökare och verksamhet men Àven boende i nÀromrÄdet.
Den övergripande metoden för detta projekt Àr evidensbaserad design. Gestaltningens stomme utgörs av en förstudie som syftar till att förklara sambandet mellan vistelse i naturen och pÄskyndad ÄterhÀmtning samt skapa förstÄelse för platsen, dess verksamheter, mÄlgrupper, möjligheter och utmaningar. Informationen frÄn förstudien har sedan översatts i en programplan som ligger till grund för gestaltningen som avser att frÀmja ÄterhÀmtning och stressreducering.
Gestaltningsförslaget, PĂ€rlor i det gröna, gör SĂ€vja kyrkas utomhusmiljö till en tillgĂ€nglig grönmiljö som erbjuder olika former av Ă„terhĂ€mtning anpassade efter olika behov, mĂ„ende och sinnestillstĂ„nd. Ăven kopplingen till omgivande natur har stĂ€rkts. Förslagets grundstomme utgörs av vegetation och planteringsytor som kompletteras av byggda strukturer i form av vistelseytor integrerade i det gröna. Detta gör det möjligt för besökare att spendera en lĂ€ngre tid pĂ„ platsen och ta del av miljöns Ă„terhĂ€mtande och stressreducerande kvaliteter.
Gestaltningen av SÀvja kyrkas utomhusmiljö visar hur det Àr möjligt att genom landskapsarkitektur bidra till att frÀmja folkhÀlsan genom att sÀkerstÀlla tillgÄngen pÄ högkvalitativa bostadsnÀra grönytor.Today's society is constantly growing, and urbanization is becoming an increasingly common phenomenon. Exploitation and densification are nowadays a natural part of community development and can theoretically generate a suitable living environment. However, it also causes increasing mental strain and stress due to the fast pace inside the city, lots of impressions daily, and lack of time to recover.
When cities expand, recreational areas are often used for development, and the distance to nature increases as city boundaries expand. Due to the growing distances, many residents do not find time to spend time in nature daily, which research believes is essential to ensure good public health in the growing cities.
The lack of green spaces close to residential areas on account of exploitation is highly relevant to today's landscape architects. The dilemma raises questions about how it is possible to increase the availability of green spaces to ensure the sustainable development of future cities.
SĂ€vja church, in southeast Uppsala, is surrounded by 0.6 hectares of natural land, which is currently perceived as inaccessible and untapped. Southeastern Uppsala is facing significant development, which makes this a case where the quality of the existing green areas should be a priority. A larger target group can appreciate nature through a design proposal for SĂ€vja church's outdoor environment, which intends to promote recovery and stress reduction. The proposal is the result of the essay and intends to make SĂ€vja church's outdoor environment a health-promoting place for the church's visitors and residents in the immediate area.
The methodology for this project is evidence-based design. The design framework consists of a preliminary study that aims to explain the connection between staying in nature and accelerated recovery and to create an understanding of the place, its activities, target groups, opportunities, and challenges. The information from the preliminary study has then been translated into a program plan that forms the basis of the design, which aims to promote recovery and stress reduction.
The design proposal, Pearls in the green, makes SĂ€vja church's outdoor environment into an accessible green environment that offers different forms of recovery adapted to different needs, moods, and states of mind. The connection to the surrounding nature has also been strengthened. The basic structure of the proposal consists of vegetation and planting areas which are complemented by built structures in the form of sojourn areas integrated into the green. This enables visitors to spend a longer time at the site and participate in the environment's recovering and stress-reducing qualities.
The design of SĂ€vja church's outdoor environment shows how it is possible to promote public health through landscape architecture by ensuring the availability of high-quality green areas close to residential areas
A healthy dose of Lynch : a study of how health-enhancing environmental qualities can be included in analysis methods based on Kevin Lynchâs theory
Omfattande trender av urbanisering och förtĂ€tning har medfört hĂ€lsorelaterade utmaningar, dĂ„ urbana grönomrĂ„den ofta tas i ansprĂ„k för exploatering. Medan mĂ„nga studier har undersökt grönomrĂ„dens olika hĂ€lsorelaterade fördelar, har desto fĂ€rre behandlat en inkludering av hĂ€lsoaspekter i vĂ€lanvĂ€nda stadsplaneringsteorier. Denna uppsats har till syfte att undersöka möjligheten att inkludera hĂ€lsofrĂ€mjande miljökvaliteter i Kevin Lynchs teori om stadens fem element, som anvĂ€nds vid analys och utformning av stĂ€der. Detta för att utveckla en analysmetod baserad pĂ„ Lynchs teori som möjliggör att hĂ€lsofrĂ€mjande aspekter tas i hĂ€nsyn. HĂ€lsoaspekter representeras teoretiskt av perceived sensory dimensions (PSDs), vilka uttrycker Ă„tta generella mĂ€nskliga behov i relation till urbana grönomrĂ„den. Relationen mellan PSDs och Lynchs teori undersöks genom att tillĂ€mpa teorierna i analyser av Eriksberg, Uppsala, och sedan jĂ€mföra resultatet av de bĂ„da analyserna med varandra. Resultatet visar att det finns samband mellan PSDs och Lynchs teori, dĂ€r PSDs kan anvĂ€ndas för att utveckla en analysmetod baserad pĂ„ Lynchs teori. I analysmetoden tillför PSDs beskrivningar om vilka hĂ€lsofrĂ€mjande kvaliteter elementen innehar eller bidrar med. Indelningen av PSDs i motsatspar kan ocksĂ„ vara ett verktyg i analysmetoden, för att bĂ€ttre förstĂ„ olika platsers förutsĂ€ttningar och behov. Utvecklingen av analysmetoden Ă€r ett första steg i framtagandet av ett verktyg som kan försĂ€kra att hĂ€lsofrĂ€mjande aspekter tas i hĂ€nsyn vid analys och utformning av stĂ€der.Comprehensive trends of urbanisation and densification have brought challenges regarding health aspects, as urban green spaces often frequently become the site of for new buildings. While many studies have examined different health benefits of green spaces, fewer have concerned the inclusion of health aspects in well-used urban planning theories. This thesis aims to review the possibilities of including health-enhancing environmental qualities in Kevin Lynchâs theory of the five elements of the city, which is used in urban analysis and design. This in order to develop an analysis method based on Lynchâs theory that enables health-enhancing aspects to be taken into consideration. The health aspects are theoretically represented by perceived sensory dimensions (PSDs), which express eight general human needs in relation to urban green spaces. The relationship between PSDs and Lynchâs theory is examined by applying the theories in analyses of Eriksberg, Uppsala, then comparing the results of both analyses with each other. The result shows that there are connections between the PSDs and Lynchâs theory, where the PSDs can function as a tool for further developing an analysis method based on Lynchâs theory. In the analysis method, the PSDs add descriptions of which health-enhancing qualities the elements have or contribute to. The division of PSDs in opposing pairs can also be a tool in the analysis method, to better understand the conditions and needs of different places. The development of the analysis method is a first step in creating a tool that can ensure that health-enhancing qualities are considered in urban analysis and design
Preservation and alteration at Ăstra kyrkogĂ„rden in Malmö : a design proposal for the memory grove and surrounding area
I dagens urbaniserade samhĂ€lle avtar intresset för den traditionella begravningsplatsen samtidigt som trycket pĂ„ stadsnĂ€ra grönytor ökar. Detta har lett till att begravningsplatser i allt större utstrĂ€ckning anvĂ€nds likt parker vilket har gett upphov till konflikt. Begravningsplatser skyddas i mĂ„nga fall av lagar som strĂ€var efter att bevara dess befintliga karaktĂ€r och funktion. I linje med detta Ă€r förĂ€ndring av begravningsplatser utmanande samtidigt som det Ă€r nödvĂ€ndigt för att tillgodose samhĂ€llets nya behov. Behovet av anpassning har bland annat uppmĂ€rksammats i Malmö dĂ€r Ăstra kyrkogĂ„rden, gestaltad av Lewerentz, stĂ„r inför förĂ€ndring. Begravningsplatsens minneslund och omgivande yta behöver utvecklas för att följa med i tiden medan dess ursprungliga karaktĂ€r inte fĂ„r gĂ„ förlorad. Uppsatsen Ă€mnar undersöka möjligheten till utveckling av begravnings-platser, med hĂ€nsyn till kraven för bevarande, samt den nutida synen pĂ„ begravningsplatsers funktion i samhĂ€llet. En litteraturstudie och ett platsbesök, pĂ„ Ăstra kyrkogĂ„rden, ligger till grund för en analys som redogör för slutsatser gĂ€llande vilka aktiviteter som bör prioriteras. Dessa sammanstĂ€lls sedan i en gestaltning, av minneslunden och omgivande yta, dĂ€r balansen mellan bevarande och förĂ€ndring behandlas. Gestaltningen landade i förslaget âCirklar av livâ och stora delar av platsens befintliga karaktĂ€r har bevarats med hĂ€nsyn till dess kulturhistoriska arv. TillĂ€ggen avser frĂ€mst att gynna platsens Ă„terhĂ€mtande kvalitĂ©er och men Ă€ven tillĂ„ta rekreativ aktivitet.Interest in the traditional cemetery decreases while the need for green spaces close to the city escalates in todayâs urbanized society. This has led to an increasing use of cemeteries as recreational parks, which has given rise to conflict. Cemeteries are most often protected by laws that strive to preserve their existing character and function. Accordingly, reshaping cemeteries is challenging and at the same time a necessity to meet the needs of society. The need for adaptation has been noticed in Malmö, among other places, where Ăstra kyrkogĂ„rden, designed by Lewerentz, is facing change. The memorial grove and surrounding area need to be restored and developed, to adapt to todayâs society, while its original character must be preserved. This essay intends to investigate the possibility of developing cemeteries, with regard to the requirements for preservation, as well as the current view of the function of cemeteries in modern society. A literature study and a visit at the Ăstra kyrkogĂ„rden, form a basis for the analysis that presents conclusions considering which activities should be prioritized. The memorial grove and surrounding area are then complied and interpretated in a landscape plan, and the balance between preservation and alteration is taken under consideration. The design landed in the proposal âCircles of Lifeâ where large parts of the existing character of the place have been preserved with consideration to its cultural heritage. The additions made are primarily intended to promote the restorative qualities of the site but also allow recreational activity
It doesnât work on its own! : a case study of the project âAlsike klosterbyâ
Syftet med detta kandidatarbete inom Ă€mnet landsbygdsutveckling, Ă€r att undersöka och beskriva hur ideellt engagemang rörande flyktingintegration- och miljöfrĂ„gor kan organiseras pĂ„ lokal nivĂ„. Jag har studerat ett projekt som i dagslĂ€get drivs pĂ„ Alsike kloster som ligger strax utanför Knivsta, i Uppland. Projektet syftar till att etablera en ekologisk klosterby vars mĂ„l Ă€r integrera flyktingarbete med ett hĂ„llbart ekologiskt levnadssĂ€tt. Föreliggande studie bygger pĂ„ intervjuer med projektdeltagare samt observationer frĂ„n planeringsmöten med projektet. Med hjĂ€lp av begreppen sociala nĂ€tverk, ideell organisation och komplexa system försöker jag beskriva och förstĂ„ hur detta specifika projekt organiseras, vilka drivkrafter som ligger bakom engagemanget hos projektdeltagarna samt vad som upplevs som möjligheter och svĂ„righeter i projektets arbetsprocess. Studien visar att projektet omfattar flera sociala nĂ€tverk som via sociala relationer kopplas sam-man och bidrar till projektarbetets framgĂ„ng. DĂ€rtill visar studien att projektet prĂ€glas av flexibilitet dĂ„ de ofta prövar sig fram, snarare Ă€n följer en alltför given plan. Studien av projektet âAlsike klosterbyâ kan bidra till förstĂ„elsen av sociala nĂ€tverks betydelse för organisering av projekt.The aim of this bachelor thesis in rural development is to describe how engagement concerning issues of integration of refugees- and environmental can be organized at a local level. I have studied a project that is run by Alsike Monastery which is located in a smaller society outside Knivsta, Uppland County. The aim of the project is to combine work with integration of refugees with ecological farming. The study is based on several interviews with project participants and observations from the projectâs planning meetings. I have with help from theories about social networks, non-profit organizations and complex systems, tried to describe and understand how this specific project is organized, what driving forces the participants have as well as the perceived possibilities and challenges in the working process. This study shows that the project encompasses several social networks that are connected through social relations contributing to the success of the project. Moreover, the study depicts the uniqueness of the project as well as its flexibility. The project often tries different routes, evaluating along the way, rather than following a pre-made plan. The study of âAlsike Monastry Villageâ can contribute to the understanding of the importance of social networks in the organization of projects
Broad-Spectrum Antibiotic Treatment and Subsequent Childhood Type 1 Diabetes: A Nationwide Danish Cohort Study
International audienceBackground: Treatment with antibiotics in early childhood is effective for bacterial infections but may have long-term side effects. We evaluated the effect of broad-spectrum antibiotics treatment during the first two years of life in association with mode of delivery on subsequent onset of childhood type 1 diabetes.Methods: A Danish Nationwide cohort study included all singletons born during 1997-2010. Five national registers provided information on antibiotic redemption, outcome and confounders. The risk of type 1 diabetes with onset before the age of 15 years was assessed by Cox regression. A total of 858,201 singletons contributed 5,906,069 person- years, during which 1,503 children were diagnosed with type 1 diabetes.Results: Redemption of broad-spectrum antibiotics during the first two years of life was associated with an increased rate of type 1 diabetes during the following 13 years of life (HR 1.13; 95% CI 1.02 to 1.25), however, the rate was modified by mode of delivery. Broad- spectrum antibiotics were associated with an increased rate of type 1 diabetes in children delivered by either intrapartum cesarean section (HR 1.70; 95% CI 1.15 to 2.51) or prelabor cesarean section (HR 1.63; 95% CI 1.11 to 2.39), but not in vaginally delivered children. Number needed to harm was 433 and 562, respectively. The association with broad-spectrum antibiotics was not modified by parity, genetic predisposition or maternal redemption of antibiotics during pregnancy or lactation.Conclusions: Redemption of broad-spectrum antibiotics during infancy is associated with an increased risk of childhood type 1 diabetes in children delivered by cesarean section
Inventory study of an early pandemic COVID- 19 cohort in South-Eastern Sweden, focusing on neurological manifestations
Background Neurological manifestations in patients with COVID-19 have been reported previously as outcomes of the infection. The purpose of current study was to investigate the occurrence of neurological signs and symptoms in COVID-19 patients, in the county of
6sterg\uf6tland in southeastern Sweden. Methods This is a retrospective, observational cohort study. Data were collected between March 2020 and June 2020. Information was extracted from medical records by a trained research assistant and physician and all data were validated by a senior neurologist. Results Seventy-four percent of patients developed at least one neurological symptom during the acute phase of the infection. Headache (43%) was the most common neurological symptom, followed by anosmia and/or ageusia (33%), confusion (28%), hallucinations (17%), dizziness (16%), sleep disorders in terms of insomnia and OSAS (Obstructive Sleep Apnea) (9%), myopathy and neuropathy (8%) and numbness and tingling (5%). Patients treated in the ICU had a higher male presentation (73%). Several risk factors in terms of co-morbidities, were identified. Hypertension (54.5%), depression and anxiety (51%), sleep disorders in terms of insomnia and OSAS (30%), cardiovascular morbidity (28%), autoimmune diseases (25%), chronic lung diseases (24%) and diabetes mellitus type 2 (23%) founded as possible risk factors. Conclusion Neurological symptoms were found in the vast majority (74%) of the patients. Accordingly, attention to neurological, mental and sleep disturbances is warranted with involvement of neurological expertise, in order to avoid further complications and long-term neurological effect of COVID-19. Furthermore, risk factors for more severe COVID-19, in terms of possible co-morbidities that identified in this study should get appropriate attention to optimizing treatment strategies in COVID-19 patients
Rosette-Disrupting Effect of an Anti-Plasmodial Compound for the Potential Treatment of Plasmodium falciparum Malaria Complications
The spread of artemisinin-resistant parasites could lead to
higher incidence of patients with malaria complications.
However, there are no current treatments that directly dislodge
sequestered parasites from the microvasculature. We show that
four common antiplasmodial drugs do not disperse rosettes
(erythrocyte clusters formed by malaria parasites) and therefore
develop a cell-based high-throughput assay to identify potential
rosette-disrupting compounds. A pilot screen of 2693 compounds
identified Malaria Box compound MMV006764 as a potential
candidate. Although it reduced rosetting by a modest 20%,
MMV006764 was validated to be similarly effective against both
blood group O and A rosettes of three laboratory parasite lines.
Coupled with its antiplasmodial activity and drug-likeness,
MMV006764 represents the first small-molecule compound that
disrupts rosetting and could potentially be used in a
resource-limited setting to treat patients deteriorating rapidly
from malaria complications. Such dual-action drugs that
simultaneously restore microcirculation and reduce parasite load
could significantly reduce malaria morbidity and mortality
The interactive role of predation, competition and habitat conditions in structuring an intertidal bivalve population
Habitat characteristics, predation and competition are known to interactively drive population dynamics. Highly complex habitats, for example, may reduce predation and competition, allowing more individuals living together in a certain area. However, the strength and direction of such interactions can differ strongly and are context dependent. Furthermore, as habitat characteristics are rapidly changing due to anthropogenic impacts, it becomes increasingly important to understand such interactions. Here, we studied the interactive effects of predation and competition on common cockle (Cerastoderma edule) recruitment, growth and survival under different habitat characteristics in the Wadden Sea, one of the world's largest intertidal ecosystems. In a predator-exclosure experiment, we manipulated cockle densities (100 vs. 1000 individuals m-2) and shorebird predation at two sites differing in habitat characteristics, namely at the wake of a blue mussel bed (Mytilus edulis) and at an adjacent sandy site. We found that recruitment was higher in the mussel-modified habitat, most likely due to reduction of hydrodynamic stress. Although bird predation strongly reduced recruit density, the combined effects still yielded more recruitment at the vicinity of the mussel bed compared to the sandy area. Furthermore, we found that high cockle densities combined with high densities of other potential prey (i.e. mussels) at the mussel-modified site, mitigated predation effects for adult cockles. Apart from these positive effects on adults, mussel-modified habitat reduced cockle growth, most likely by reducing hydrodynamics in the wake of the mussel bed and by increasing inter-specific competition for food. Our study experimentally underpins the importance of habitat characteristics, competition and predation in interactively structuring intertidal communities
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