Electrospinning: Avances y aplicaciones en el campo de la biomedicina: Electrospinning: Advances and applications in the field of biomedicine

Nanofiber production in scaffolds using electrospinning technology encompasses many physical and chemical parameters that have been studied and have not yet been fully elucidated. Both the use of natural polymers, which due to their characteristics have a higher affinity and a greater biocompatibility with cellular processes, as well as a biomimetization similar to the structure of the body's natural cellular matrix; however, the lack of control over some of its physical characteristics directly affects the biological characteristics of the cell. On the other hand, the use of synthetic polymers allows us to control physical characteristics, but this affects the development of cells. For this reason, this article presents a brief review of scientific articles about Electrospinning and the most used materials for obtaining scaffolds in the field of biomedicine.La producción de nanofibra en scaffolds utilizando la tecnología de electrospinning abarca muchos parámetros tanto físicos como químicos que han sido estudiados y que todavía no se han dilucidado completamente. Tanto la utilización de polímeros naturales, que por sus características tienen una mayor afinidad y una mayor biocompatibilidad con los procesos celulares, así mismo, una biomimetizacion similar a la estructura de la matriz celular natural del cuerpo; sin embargo, la falta de control sobre algunas sus características físicas repercuten directamente en características biológicas de la célula. Por otro lado, la utilización de polímeros sintéticos nos permite controlar características físicas, pero esto afecta el desarrollo de las células. Por ello, este artículo presenta una breve revisión de artículos científicos acerca del electrospinning y los biomateriales más utilizados para la obtención de scaffolds en el campo de la biomedicina.&nbsp

Enzootic transmission of yellow Fever virus, Venezuela

Phylogenetic analysis of yellow fever virus (YFV) strains isolated from Venezuela strongly supports YFV maintenance in situ in Venezuela, with evidence of regionally independent evolution within the country. However, there is considerable YFV movement from Brazil to Venezuela and between Trinidad and Venezuela.status: publishe

Evolutionary and Ecological Characterization of Mayaro Virus Strains Isolated during an Outbreak, Venezuela, 2010

In 2010, an outbreak of febrile illness with arthralgic manifestations was detected at La Estación village, Portuguesa State, Venezuela. The etiologic agent was determined to be Mayaro virus (MAYV), a reemerging South American alphavirus. A total of 77 cases was reported and 19 were confirmed as seropositive. MAYV was isolated from acute-phase serum samples from 6 symptomatic patients. We sequenced 27 complete genomes representing the full spectrum of MAYV genetic diversity, which facilitated detection of a new genotype, designated N. Phylogenetic analysis of genomic sequences indicated that etiologic strains from Venezuela belong to genotype D. Results indicate that MAYV is highly conserved genetically, showing ≈17% nucleotide divergence across all 3 genotypes and 4% among genotype D strains in the most variable genes. Coalescent analyses suggested genotypes D and L diverged ≈150 years ago and genotype diverged N ≈250 years ago. This virus commonly infects persons residing near enzootic transmission foci because of anthropogenic incursions. [ABSTRACT FROM AUTHOR] Copyright of Emerging Infectious Diseases is the property of Centers for Disease Control & Prevention (CDC) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder\u27s express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract