8 research outputs found
Educação médica em Portugal
- Publication venue
- 'Ordem dos Medicos'
- Publication date
- 01/01/2016
- Field of study
Copyright © Ordem dos Médicos 2016Medical education is an always evolving métier and mission. More than just emphasizing scientific knowledge, it is nowadays expected that it incorporates clinical reasoning, practical skills, and stimulates the development of character, compassion, and integrity. Most medical schools education results chiefly from tradition rather than evidence, and little has changed with regard to delivering top notch professionals in healthcare.info:eu-repo/semantics/publishedVersio
Bibliotecas e serviços de documentação de saúde em Portugal: situação actual
- Publication venue
- Actas do Congresso Nacional de Bibliotecários, Arquivistas e Documentalistas
- Publication date
- 23/05/2001
- Field of study
Em Portugal existe um número significativo de bibliotecas e serviços de informação directa ou indirectamente ligados às instituições de saúde.Em 1988, o então Grupo de Trabalho de Informação em saúde (GTIS) – embrião da actual APDIS – elaborou o Repertório das Bibliotecas e Serviços de Informação em Saúde [1] com o objectivo de definir o perfil das bibliotecas e serviços de documentação da saúde em Portugal.Tendo-se revelado um importante instrumento de trabalho, havia que actualizá-lo, o que levou a que, em 1992, se fizesse uma recolha de dados mais exaustiva, procurando obter informação sobre diferentes aspectos, tais como, fundo documental, técnicas de tratamento documental, informatização dos serviços, número de funcionários, tipologia dos utilizadores e serviços prestados, tendo sido publicado novo Repertório em 1993 [2]. Em 1996, estes resultados foram tratados, analisados e apresentados na 5ª Conferência da European Association of Medical and Health Libraries [3] .Tornava-se importante, uma vez mais, actualizar a informação disponível e introduzir novos elementos, tendo o Grupo de Trabalho do Repertório da APDIS iniciado em 1999 novo levantamento de informação através de um inquérito enviado a 217 organismos da saúde.Em resposta ao questionário lançado, obteve-se um conjunto de 114 resposta, ou seja, apenas 49% do universo inquirido. Seguindo a linha de orientação definida desde o primeiro Repertório, os diferentes serviços foram agrupados geograficamente por regiões, obtendo 31 respostas da região Norte, 26 do Centro, 41 de Lisboa e Vale do Tejo, 4 do Alentejo e 7 das Regiões Autónomas dos Açores e da Madeira.Para além dos elementos já contemplados no anterior Repertório, deu-se ênfase aos aspectos relacionados com as novas tecnologias da informação, como sejam, o tipo de suporte dos documentos, a assinatura de bases de dados bibliográficos e de texto integral, a existência de ligação à Internet e de serviços disponíveis em rede, etc.É o resultado deste inquérito — do seu tratamento e da sua interpretação — que os elementos do Grupo de Trabalho pretendem divulgar nesta apresentação
Fifth European Dirofilaria and Angiostrongylus Days (FiEDAD) 2016
- Author
- Acatrinei Dumitru
- Alho Ana Margarida
- Alho Ana Margarida
- Ambalov Yuri
- Angelou Athanasios
- Aranđelović Momčilo
- Arbune Mihaela
- Auer Herbert
- Auriemma Edoardo
- Barutzki Dieter
- Bastrikov Nikolay
- Bayrou Calixte
- Bedel Benjamin
- Bekvalac Rastko
- Belo Silvana
- Belo Silvana
- Benchekroun Ghita
- Beurlet Stéphanie
- Blaga Radu
- Blaga Radu
- Blot Stéphane
- Bowman Dwight D.
- Butter Julia
- Caceres Sara
- Capelli Gioia
- Cardoso Luís
- Cardoso Luís
- Carretón Elena
- Carretón Elena
- Chandrashekar Ramaswamy
- Chaparro Jenny
- Chetboul Valérie
- Chizh Nina
- Ciuca Lavinia
- Conboy Gary
- Conboy Gary
- Constantin Roman
- Cortes Helder C. E.
- Cuk Claudia
- Cvetković Milan
- Czopowicz Michał
- Dalemans Anne-Catherine
- Daniel-Lesnard Virginie
- de Carvalho Luís Madeira
- de Carvalho Luís Madeira
- Deak Georgiana
- Dennebaum Martin
- Di Cesare Angela
- Di Cesare Angela
- Di Palma Stefano
- Diakou Anastasia
- Diakou Anastasia
- Diosdado A.
- Diosdado Alicia
- Diosdado Alicia
- Dobrica Anca M.
- Dobrzyński Artur
- Dobrzyński Artur
- Dontsov Denis
- Dudko Paulina
- Duscher Georg G.
- Dyachenko Viktor
- Długosz Ewa
- Długosz Ewa
- Džamić Aleksandar M.
- D’Amico Gianluca
- Elsheikha Hany M.
- Ermakov Alexey
- Fenjac Ivan
- Florea Cristian-Ionut C. N.
- Fok Éva
- Forshell Ulrika
- Fritzenwanker Moritz
- Fuehrer Hans-Peter
- Fuehrer Hans-Peter
- Gallidis Eleftherios
- Garofani Cecilia
- Gherman Călin M.
- Gillis-Germitsch Nina
- González-Miguel J.
- González-Miguel Javier
- González-Miguel Javier
- González-Miguel Javier
- Gori Francesca
- Gouni Vassiliki
- Granada Sara
- Grandi Giulio
- Grillotti Eleonora
- Grzybek Maciej
- Guillot Jacques
- Guselle Nicole
- Gutiérrez Jesed
- Gärtner Uwe
- Gómez P. J.
- Gómez Paula Josefina
- Hansen Alice P.
- Hermosilla Carlos
- Hermosilla Carlos
- Hermosilla Carlos
- Hofmannová Lada
- Hofstede Tamara
- Holmes Sarah B.
- Hurjui Loredana
- Hurníková Zuzana
- Ibba Fabrizio
- Illera Juan Carlos
- Ilyasov Boris
- Ionică Angela M.
- Ionică Angela Monica
- Iwanicki Ryszard
- Joachim Anja
- Junkuszew Andrzej
- Juránková Jana
- Kalezić Tanja
- Kartashev V.
- Kartashev Vladimir
- Kartashov Sergey
- Klaudiusz Szczepaniak
- Klockiewicz Maciej
- Klockiewicz Maciej
- Korzan Alla
- Kosic Ljubica Spasojevic
- Koutinas Christos
- Kramer Laura
- Kramer Laura
- Kroidl Inge
- Krzysztof Tomczuk
- Krücken Jürgen
- Kucsera István
- Kuruca Ljiljana
- Lalosevic Vesna
- Lange Malin
- Lange Malin
- Lange Malin
- Lebl Karin
- Leitner Natascha
- Lempereur Laetitia
- Lendner Mathias
- Leschnik Michael
- Lopes Ana Patrícia
- Lopes Ana Patrícia
- Losson Bertrand
- Macchioni Fabio
- Maciek Grzybek
- Magdowski Gerd
- Magi Marta
- Manzocchi Simone
- Manzocchi Simone
- Martin Coralie
- Martinelle Ludovic
- Marzena Stefaniak
- Maréchal Françoise
- Mejer Helena
- Mejer Helena
- Migli Despina
- Mihalca Andrei D.
- Mihalca Andrei Daniel
- Milojković Nenad
- Miron Liviu
- Miterpáková Martina
- Mitková Barbora
- Mitrović Sanja
- Modrý David
- Modrý David
- Montarsi Fabrizio
- Montoya-Alonso José Alberto
- Morchón R.
- Morchón Rodrigo
- Morchón Rodrigo
- Morchón Rodrigo
- Morchón Rodrigo
- Moroti Ruxandra V.
- Murphy Nicole
- Muñoz-Caro Tamara
- Mylonakis Mathios
- Naglic Aleksandar
- Nawratil Michaela
- Nikola Pantchev
- Nikolaenko Svetlana
- Novotná Marcela
- Nowakowska Joanna
- Obwaller Adelheid
- Olaru Stefan P.
- Oliveira Ana Cristina
- Olsen Caroline S.
- Osterman-Lind Eva
- Otasevic Suzana
- Otranto Domenico
- Otranto Domenico
- Pampurini Fabrizio
- Panic Vladan
- Pantchev Nikola
- Pantchev Nikola
- Papadopoulos Elias
- Parzeniecka-Jaworska Marta
- Pavlikovska Tamara
- Peloso Martina
- Penagos Felipe
- Penagos Felipe
- Penagos Felipe
- Petric Dusan
- Peña Laura
- Piedrahita Diego
- Polack Bruno
- Polack Bruno
- Polizopoulou Zoe
- Poppert Sven
- Potkonjak Aleksandar
- Psalla Dimitra
- Pudar Dubravka
- Ramünke Sabrina
- Rašić Dejan
- Rinaldi Laura
- Rivera A.
- Ryszard Iwanicki
- Sagach Olga
- Salauyova Alena
- Savic Sara
- Savic Sara
- Schaper Roland
- Schaper Roland
- Schaper Roland
- Schaper Roland
- Schaper Roland
- Schaper Roland
- Schaper Roland
- Schnyder Manuela
- Schnyder Manuela
- Schnyder Manuela
- Schnyder Manuela
- Silaghi Cornelia
- Siles-Lucas M.
- Siles-Lucas Mar
- Silvan Gema
- Simin Stanislav
- Simon Fernando
- Simón F.
- Simón Fernando
- Simón Fernando
- Skarbye Line K.
- Spanoudis Kyriakos
- Spasovic Aleksandar
- Szczepaniak Klaudiusz
- Szmidt Agnieszka
- Taubert Anja
- Taubert Anja
- Taubert Anja
- Tomczuk Krzysztof
- Traversa Donato
- Traversa Donato
- Tudor Poliana Gh
- Ulivieri Elisa
- Velez Juan D.
- Venco Luigi
- Verwaerde Patrick
- Vila-Viçosa Maria João
- Vilhena Hugo
- Vinther Lene M.
- von Samson-Himmelstjerna Georg
- Votýpka Jan
- Weiss Stefan
- Willesen Jakob L.
- Wimmer Victoria
- Wimmer Victoria
- Wongkamchai Sirichit
- Wysmołek Magdalena
- Wysmołek Magdalena
- Yilmaz Esra
- Youlatos Dionisios
- Zechmeister Thomas
- Zittra Carina
- Zittra Carina
- Übleis Sarah S.
- Ćurčin Ljubomir
- Čabanová Viktória
- Čalovski Ivana Čolović
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Peer reviewe
Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study
- Author
- \u160a\u161inkov\ue1 Pavla
- \u160enk\ue1rov\ue1 Zuzana
- \uc5man Jaana
- Aaserud Olaf
- Abbruzzese Giovanni
- Agarwal Veena
- Akhtar Shahbana
- Alarc\uf3n Moreau Mar\ueda Dolores
- Albanese Alberto
- Allain Philippe
- Almagro Carmen Ant\ufanez
- Almeida Manuel
- Alonso-Frech Fernando
- Alusi Sundus
- Anderson Mary
- Andersson Christian
- Andrade Carlos
- Andrew Alyson
- Andrews Thomasin
- Andrich J\ufcrgen
- Angeles Maria
- Aniola Jacek
- Anjum Uruj
- Annic Agn\ue8s
- Antczak Jakub
- Arbelo Jos\ue9 Mat\uedas
- Arkuszewski Michal
- Armstrong Richard
- Arntsen Vibeke
- Arques Penelope Navas
- Arran Natalie
- Artiga Mar\ueda Jos\ue9 Sainz
- Azulay Jean-Philippe
- B\ue1rcenas Antonio Herranz
- B\uf6ringer Regina
- Baake Verena
- Babiloni Blandine
- Bachmeier Michael
- Bachoud-L\ue9vi Anne-Catherine
- Badei Farideh
- Bailey Wendy
- Banaszkiewicz Krzysztof
- Bandmann Oliver
- Barbera Miquel Aguilar
- Barker Roger A.
- Barral Ver\uf3nica Ma\uf1anes
- Barrero Francisco
- Barth Katrin
- Barth\ue9l\ue9my Recka
- Bas Jordi
- Bechtel Natalie
- Beckmann Heike
- Bek Judith
- Bellonet Marcellin
- Benaich Sandra
- Benoit Alexandra
- Bentivoglio Anna Rita
- Berglund Maria
- Berglund Peter
- Bergmann Ulrike
- Berrisoul Hassan
- Bertini Elisabetta
- Bethwaite Pamela
- Betz Sabrina
- Beuth Markus
- Bioux Sandrine
- Biunno Ida
- Bj\uf6rnsson Elisabeth
- Bj\uf8rgo Kathrine
- Bj\uf8rnevoll Inga
- Blaszczyk Magdalena
- Bliaux Evangeline
- Blin St\ue9phanie
- Blinkenberg Ellen 8kland
- Blondeau Leily
- Bo\u107wi\u144ska Dorota
- Boczarska-Jedynak Magdalena
- Boelmans Kai
- Bohlen Stefan
- Boiss\ue9 Marie-Fran\ue7oise
- Bojakowska-Jaremek Kamila
- Bojarsky Jaime Kulisevsky
- Bonelli Raphael M.
- Bonneau Dominique
- Boogaerts Andrea
- Borge\uf8d Nancy
- Bos Reineke
- Bosca Maria
- Bosredon Cecile
- Bost Marie
- Boudali Lotfi
- Bove Francesco
- Bradbury Alyson
- Braunwarth Eva-Maria
- Brice Alexis
- Brockie Peter
- Bronzova Juliana
- Brugada Francisco Castera
- Brugger Florian
- Bruno Stefania
- Bryl Anna
- Buchanan Lindsay
- Buck Andrea
- Buongiorno Mar\ueda Teresa
- Buratti Lisa
- Burguera Juan Andres
- Burgunder Jean-Marc
- Burn John
- Burrows Liz
- Busquets N\ufaria
- Busse Monica
- Butcher Cynthia
- Cabaret Maryline
- Calado Ana
- Calandra-Buonaura Giovanna
- Caldentey Juan Garc\ueda
- Callaghan Jenny
- Calopa Matilde
- Calvas Fabienne
- Calzado Noemi
- Campolongo Antonia
- Cannella Milena
- Capellari Sabina
- Capetian Philipp
- Capodarca Selene
- Cardoso Helena
- Carette Anne-Sophie
- Carri\ue8re Nicolas
- Carrillo F\ue1tima
- Carruesco Gemma Tome
- Casado Roc\uedo Villagr\ue1n
- Cass Ginette
- Castagliuolo Simona
- Castaldo Anna
- Catalli Claudio
- Catena Judit L\uf3pez
- Chabot Christelle
- Charles Perrine
- Charpentier S\ue9bastien
- Cheriet Samia
- Chu Carol
- Chu Elvina
- Ciach-Wysocka Ewelina
- Ciesielska Anna
- Classen Serge Jaum\ue1
- Clayton Carole
- Clenaghan Catherine
- Coarelli Giulia
- Codella Valentina
- Coebergh Jan
- Coelho Miguel
- Coleman Caroline
- Come Adrien
- Connemann Julia
- Constant Eric
- Constantinescu Radu
- Cormio Claudia
- Corrales Koldo Berganzo
- Cortegana Eva Mar\ueda Pacheco
- Cortelli Pietro
- Costa Andreia
- Costa Cristina
- Coulthard Elizabeth
- Courtin Fran\ue7oise
- Couttier Julien
- Craufurd David
- Craven Janet
- Crooks Jenny
- Cubillo Patricia Trigo
- Cubo Esther
- Curtis Adrienne
- D\ucdaz-Zorita Juan Pablo Tartari
- Da Silva Wildson Vieira
- Das Purkayastha Debasish
- Davidson Lynn
- Davies Rhys
- Davison Jill
- De Bobadilla Ramon Fernandez
- De Bruycker Christelle
- De Gregorio Francesca
- De La Cerda Santa Mar\ueda Andr\ue9s
- De Langavant Laurent Cleret
- De Michele Giuseppe
- De Molina Roc\uedo Malo
- De Nicola Annunziata
- De Souza Keylock Jenny
- De Tommaso Marina
- De Weert A. Marit
- De Y\ue9benes Justo Garc\ueda
- Debilly B\ue9reng\ue8re
- Debruxelles Sabrina
- Dec Malgorzata
- Decorte Eric
- Dedich\ue1 Nadia Rodr\uedguez
- Defebvre Luc
- Deith Catherine
- Dekker Meike
- Del Mar Fenollar Mar\ueda
- Del Valle Loarte Mar\ueda
- Delabaere Hel\ue8ne
- Delaigue Christine
- Delfini Marie
- Delliaux Marie
- Delval Arnaud
- Demonet Jean-Fran\ue7ois
- Depelchin Aliz\ue9
- Destee Alain
- Dewulf-Pasz Nelly
- DI Bella Daniela
- DI Donato Stefano
- DI Giacopo Raffaella
- DI Maio Luigi
- DI Maria Emilio
- DI Pietro Anna Gerrtiz
- DI Poggio Monica Bandettini
- DI Renzo Martina
- DI\ue9guez Esther
- DIas Margarida
- DIercks Gabriele
- DIfruscolo Olimpia
- DIpple Heather
- Doherty Karen
- Dondaine Thibaut
- Donovan John O
- Dose Matthias
- Dougherty Andrew
- Downie Lorna
- Dramstad Elisabeth
- Dressler DIrk
- Duch\ue9 Charlotte
- Dugauquier Florence
- Duits Annelien
- Dujardin Kathy
- Dumas Eve M.
- Dunnett Stephen
- Dupuis Michel
- Durif Franck
- Durr Alexandra
- Duru C\ue9cile
- Dziadkiewicz Artur
- Ecker Daniel
- Eddy Charlotte
- Edwards Maureen
- Edwards Rachel
- Eklund Pia
- Ekwall Camilla
- Elifani Francesca
- Ellrichmann Gisa
- Esposito Federica
- Esteban Juan Carlos Gomez
- Eusebio Alexandre
- Evans Carole
- Ewenczyk Claire
- Fairtlough Helen
- Fannemel Madeleine
- Farewell Daniel
- Fasano Alfonso
- Fasquel V\ue9ronique
- Fernandez Cristina Melgar
- Ferraldeschi Michela
- Ferrandes Giovanna
- Ferreira Joaquim J
- Ferrer Pilar Quil\ue9z
- Figuerola Bego\uf1a Jeweinat
- Fillingham Kay
- Finisterra Ana Maria
- Fisher Kate
- Flament M\ue9lanie
- Fletcher Amy
- Fluchere Fr\ue9d\ue9rique
- Fortuna Lorenza
- Foster Jillian
- Foustanos Isabella
- Foy Kevin
- Frades Bel\ue9n
- Francis Flverly
- Francisque H\ue9l\ue8ne
- Franco Giovanni
- Frech Fernando Alonso
- Fredlund Gunnel
- Freire-Patino Dawn
- Frich Jan C.
- Frontali Marina
- Frost Julie
- Fullam Ruth
- Fuller Kathleen
- G\uf6ller Marie-Lousie
- G\uf6pfert Nicole
- G\uf8rvell Per F.
- Gago Miguel
- Gallassi Roberto
- Gallentree Deena
- Ganos Christos
- Garc\ueda Ana
- Garc\ueda Roc\uedo Garc\ueda-Ramos
- Garcia-Amigot Fermin
- Garde M\uf3nica Bascu\uf1ana
- Garrett Carolina
- Gaston Itziar
- Gayde-Stephan Sabine
- Geitner Carolin
- Gelderblom Harald
- Gellera Cinzia
- Genitrini Silvia
- Genoves Camille
- Gerrans Emily
- Ghelli Elena
- Gil Acera
- Gill Paul
- Gillardin Anne-Fran\ue7oise
- Gilling Mette
- Ginestroni Andrea
- Girard Carole
- Giuliano Joe
- Godefroy Olivier
- Goerendt Ines
- Gogol Anna
- Gohier B\ue9n\ue9dicte
- Goizet Cyril
- Golding Charlotte
- Gonz\ue1lez Amaia
- Gonz\ue1lez Laura Vargas
- Gonz\ue1lez Sonia
- Good Jean-Marc
- Goodman Anna
- Gorzkowska Agnieszka
- Gorzolla Heike
- Goudie David
- Gowers Lesley
- Grabska Natalia
- Grosjean H\ue9l\ue8ne
- Gu\ue9rid Marie-Anne
- Guedes Leonor Correia
- Guia Dolors Badenes
- Guidubaldi Arianna
- Guimar\ue3es Joana
- Guisasola Luis Men\ue9ndez
- Gunner Kerry
- Guyant-Mar\ue9chal Lucie
- Guzman Natalie Valle
- H\uf6lzner Eva
- H\uf8sterey-Ugander Ulrika
- Haider Salman
- Haig-Brown DIane
- Hallam Caroline
- Hamer Stephanie
- Hametner Eva-Maria
- Handley Olivia J.
- Hannequin DIdier
- Hannier V\ue9ronique
- Harding Alison
- Hare Marianne
- Harris Kayla
- Harrison David
- Harrower Timothy
- Hart't Ellen P.
- Hartikainen Paivi
- Haug Marte Gj\uf8l
- Hauge Erik
- Hayward Beverley
- Hayward Elaine
- Hecht Karen
- Heiberg Arvid
- Heinicke Walburgis
- Held Christine
- Hensman Davina
- Hepperger Caroline
- Hermoso F\ue1tima Damas
- Hernanz Laura Casas
- Herranhof Brigitte
- Herrera Carmen Dur\ue1n
- Herrmann Lennard
- Heywood Melanie
- Hidding Ute
- Hiivola Heli
- Hill Susan
- Hjermind Lena
- Ho Carrie
- Hobson Emma
- Hoffmann Rainer
- Hofstetter Nina
- Holas Christiane
- Holl Anna
- Holmans Peter
- Hopes Lucie
- Hotter Anna
- Howard Liz
- Hughes Alis
- Hughes Max
- Hunger Ulrike
- Hunt Sarah
- Huson Susan
- Hussl Anna
- Hvalstedt Carina
- Hypp\uf6nen Hannele
- Ialongo Tamara
- Idiago Jes\ufas Miguel Ruiz
- Ignatius Jaakko
- Illarioshkin Sergey
- Illmann Torsten
- Ireland Jane
- Irvine Sarah
- J\ue4\ue4skalainen Outi
- J\ufalio Filipa
- Jachinska Katarzyna
- Jack Roisin
- Jacobsen Oda
- Jacopini Gioia
- Jameau Laetitia
- Jamieson Stuart
- Jamrozik Zygmunt
- Janik Piotr
- Janu\ue1rio Cristina
- Jasi\u144ska-Myga Barbara
- Jauffret C\ue9line
- Johns Nicola
- Johnson Liz
- Jones Lesley
- Jones Mary
- Jones Una
- Jourdain S\ue9verine
- Jung Hans H.
- Justo Damian
- K\ue4rpp\ue4 Mikko
- Kaczmarczyk Aleksandra
- Kaelin Alain
- Kaiserova Michaela
- Kajula Outi
- Kaminska Anna
- Kaminski Barbara
- Kammel Gerit
- Kampstra Anne
- Kapfhammer Hans-Peter
- Kassar Abdulrahman
- Kavalier Fred
- Kazoka Mbombe
- Kesse Andrea
- Keys Liane
- Khalil Hanan
- Kipps Christopher
- Klebe Stephan
- Klemp\ued\u159 Ji\u159\ued
- Klimberg Aneta
- Klodowska-Duda Gabriela
- Klooster Jesper
- Knight Caroline
- Kohl Zacharias
- Koivisto Susana Pro
- Komati Suresh
- Koppers Kerstin
- Koppitz Michael
- Kosinski Christoph Michael
- Kozay Christina
- Kramer Bianca
- Kraus Alison
- Kraus Peter
- Krawczyk Malgorzata
- Kremer Berry
- Krishnamoorthy Ashok
- Krysa Wioletta
- Krystkowiak Pierre
- Kubowicz Ewelina
- Kwiecinski Hubert
- L\ue9onard Marie-Claude
- L\uf3pez Rosa Guerrero
- L\uf6hle Matthias
- L\ufcsebrink Antje
- Ladurner Gunther
- Lafoucri\ue8re Danielle
- Lagha-Boukbiza Ouhaid
- Lahiri Nayana
- Laing Hana
- Lamanna Claudia
- Lambeck Johann
- Landwehrmeyer Bernhard
- Lange Herwig
- Larcher Barbara
- Large Sandra
- Larsen Ida Unmack
- Lashwood Alison
- Laur\ue1 Matilde
- Laver Fiona
- Leenders Nico
- Legendre Perrine
- Lemaire Marie-H\ue9l\ue8ne
- Lemoine Laurie
- Lemos Mar\ueda Dolores Romero
- Lesne Fabien
- Levey Jamie
- Lewerenz Jan
- Lewis Monica
- Leypold Christine
- Lezius Franziska
- Ligon-Auer Maria
- Lilek Sabine
- Lilek Stefan
- Lindquist Suzanne
- Linnsand Petra
- Loiseau Sylvie
- Lolk Annette
- Longato Nadine
- Longinus Bernhard
- Longthorpe Mandy
- Lopera Monica Rodriguez
- Loria Giovanna
- Loutfi Ghada
- Lovo Francesca
- Lozano Pablo S\ue1nchez
- Lucena Carolina Mendez
- Lundsgaard Marianne
- M\ue4chtel Miriam
- M\uf8ller Anette Torvin
- M\ufchlau Mark
- M\ufchlb\ue4ck Alzbeta
- M\ufcller Christoph
- M\ufcller Nicole
- M\ufcnchau Alexander
- M\ufcnkel Kristina
- M\ufctze Lisanne
- Maass Antonia
- MacKinnon Lesley
- Madsen Louise Hasselstr\uf8m
- Magnet Markus
- Mahlknecht Philipp
- Maiwald Robert
- Majeed Tahir
- Majerov\ue1 Veronika
- Malec-Litwinowicz Michalina
- Malt\ueate David
- Mandich Paola
- Mandich Paola
- Manouvrier Sylvie
- Mantaux B\ue9atrice
- Manzanares Salvadora
- Marcel Christophe
- Marchese Roberta
- Marcinkowski Jerzy
- Mariotti Caterina
- Mariscal Natividad
- Markova Ivana
- Marquard Ralf
- Mart\uedn Idaira
- Mart\uednez Noelia Rodr\uedguez
- Mart\uednez-Descals Asunci\uf3n
- Martikainen Kirsti
- Martin Veronica Puertas
- Martinez-Horta Saul
- Martinez-Jaurrieta Maria Dolores
- Martino Tiziana
- Mason Sarah
- Massano Jo\ue3o
- Massarelli Marco
- Mata Maite Paredes
- Matheson Kirsty
- Mazzante Irene
- McDonnell Sharon
- McEntagart Meriel
- McFadyen Paula
- McGill Marie
- McKenzie Sue
- McLean Tim
- McNulty Paul
- Mechi Claudia
- Meier Simone
- Meireles Joana
- Mendes Tiago
- Merino Beatriz Tijero
- Mestre Tiago
- Middleton Julia
- Miedzybrodzka Zosia
- Mihaylova Violeta
- Milani Paolo
- Milkereit Eva
- Minet C\ue9cile
- Minschke Rebecca
- Minster Sara
- Mir Pablo
- Modoni Anna
- Mohammed Zeid
- Moilanen Jukka
- Monin Marie-Lorraine
- Monteiro Ana
- Monza Daniela
- Morales Blas
- Moreno Jos\ue9 Luis L\uf3pez-Send\uf3n
- Moreno Jose Manuel Garc\ueda
- Moreno Patrocinio Garcia
- Morgado Graca
- Morgado Joana
- Morgan Karen
- Mu\uf1oz Esteban
- Mu\uf1oz Juan Mar\uedn
- Mundler Laura
- Murphy Helen
- Musacchio Thomas
- Musgrave Hannah
- Mustonen Aki
- Mutez Eug\ue9nie
- N\uf6th Kerstin
- Nanetti Lorenzo
- Necuiniate Renata
- Neleborn-Lingefj\ue4rd Liselotte
- Nemeth Andrea H
- Nepper Solveig
- Nevitt Louise
- Nielsen J\uf8rgen
- Niess Anke
- Noad Rupert
- Novak Marianne
- Nowak Malgorzata
- Nowak Marielle
- Nyberg Clara
- O'Donovan Kirsty
- O'Keefe Deidre
- O'Neill Mari
- Oehmen Martin
- Olivier Audrey
- Ollokainen Mari
- Olofsson Carina
- Oosterloo Mayke
- Opala Grzegorz
- Orth Michael
- Ossig Christiana
- Otti Daniela
- Oughton Emma
- Owen Michael
- P\ue4iv\ue4rinta Markku
- P\ue5lhagen Sven
- Padieu Helene
- Paganini Marco
- Pagonabarraga Javier
- Painold Annamaria
- Palanca Paloma Millan
- Palmer Amy
- Panzeri Marta
- Pardo Sonia Arribas
- Paridi Dominga
- Pariente J\ue9r\ue9mie
- Parkinson Andrew
- Partington-Jones Lucy
- Pastor Barbara Vives
- Pate Louise
- Patel Aakta
- Paterski Laurent
- Patton Michael
- Paucar Martin
- Paus Karin
- Pe\uf1a Jos\ue9 Chac\uf3n
- Peacy Caroline
- Pearson Pauline
- Peinemann Alexander
- Peippo Maarit
- Peluso Silvio
- Peppa Nadia
- Perea Fuensanta Noguera
- Perez Jesus Perez
- Peria\uf1ez Juan Manuel
- Peter Mireille
- Petersen Jens A.
- Peterson Maria
- Petracca Martina
- Petrollini Martina
- Phillipps Cl\ue9lie
- Phillips Michelle
- Piacentini Silvia
- Piano Carla
- Piccininni Chiara
- Pierre Mich\ue8le
- Pilcher Richard
- Pinter Bernadette
- Playe Alicia
- Plomhause Lucie
- Poda Roberto
- Poewe Werner
- Polo Cecilia Gil
- Porteous Mary
- Pouliquen Doroth\ue9e
- Powell Kingsley
- Pr\ufc f Harald
- Pradella Silvia
- Price Kathleen
- Prieto Marta Para
- Priller Josef
- Probst Daniela
- Prouzet Julie
- Prundean Adriana
- Pueyo Angel Mart\uednez
- Quaranta Davide
- Quarrell Oliver
- R\uf8ren Niini
- R\uf8sby Oddveig
- Rae Daniela
- Rakowicz Maryla
- Raman Ashok
- Ramesh Raviram
- Ramirez In\ue9s Legarda
- Ramos-Arroyo Maria Antonia
- Raseta Rolland
- Redondo Luis
- Redondo Mar\ueda Teresa C\ue1ceres
- Reetz Kathrin
- Regeur Lisbeth
- Reilmann Ralf
- Reisinger Karin
- Reiter Eva-Magdalena
- Retterst\uf8l Lars
- Riba\uef Pascale
- Ribacoba Ren\ue9
- Ribas Guillermo Garc\ueda
- Ribbat Michael
- Ribosa Roser
- Richter Przemyslaw
- Rickards Hugh
- Rijntjes Michel
- Rinaldi Carlo
- Rindal Beate
- Ristori Giovanni
- Ritchie Stuart
- Robert Misericordia Floriach
- Robertson Dene
- Robertson Nicola
- Robowski Piotr
- Roca Alessandro
- Roca Elvira
- Rogers Dawn
- Rohm Stefanie
- Rola Rafal
- Rolland Sandrine
- Romano Silvia
- Romero Irene
- Romero Sandra Gutierrez
- Romoli Anna Maria
- Roos Raymund A. C.
- Rose Sarah
- Rosser Anne
- Rosser Elisabeth
- Roth Jan
- Rothery Jean
- Roussel Martine
- Rowett Liz
- Roze Emmanuel
- Ru\uedz Pedro Jos\ue9 Garc\ueda
- Ruddy Deborah
- Rudolf Gabrielle
- Rudzi\u144ska Monika
- Rumpf Silke
- Russo Cinzia Valeria
- Ryglewicz Danuta
- S\ue1nchez Vicenta
- S\ue1nchez Violeta S\ue1nchez
- S\ufcssmuth Sigurd
- Sablonni\ue8re Bernard
- Saft Carsten
- Salvador Carlos
- Salvatore Elena
- Samara Husam
- Sando Sigrid Botne
- Santacruz Pilar
- Santala Maire
- Santhouse Alastair
- Sass Christian
- Savage Lois
- Scaglione Cesa
- Sch\uf6ggl Helmut
- Sch\ufcler B\ue9atrice
- Sch\ufcpbach Michael
- Scheibl Monika
- Schepers Sigrun
- Scherer-Gagou Clarisse
- Schiefer Johannes
- Schlangen Christiane
- Schmalfeld Jenny
- Schmidt Simone
- Schneider Ariane
- Schoonderbeek Anne
- Schrader Christoph
- Schwenk Daniela
- Sciruicchio Vittorio
- Sebasti\ue1n Ana Rojo
- Seliverstov Yury
- Semedo Cristina
- Sempolowicz Justyna
- Seppi Klaus
- Serpino Claudia
- Sevilla Maria Ascension Zea
- Sienkiewicz-Jarosz Halina
- Sieradzan Kasia
- Sikiric Alma
- Silva Mark
- Simonelli Maria
- Simonin Cl\ue9mence
- Simpson Sheila A
- Simpson Steve
- Sinadinosa Daniela
- Singh Baldev
- Sipponen Marjett
- Sitek Emilia
- Siuda Gill
- Slawek Jaroslaw
- Smalley Sarah
- Snowden Julie
- Sol\ueds Pilar
- Soleti Francesco
- Solito Marcella
- Soliveri Paola
- Sollom Andrea
- Soltan Witold
- Soltysiak Beverley
- Sorbi Sandro
- Sorrentino Pierpaolo
- Spadaro Maria
- Spagnolo Francesca
- Spampinato Umberto
- Sprenger Fabienne
- Spruth Eike
- Squitieri Ferdinando
- St 9pniak Iwona
- St\ue4dtler Michael
- St\uf8rseth Hanna Haugan
- Staffen Wolfgang
- Stamm Christiane
- Stattin Eva-Lena
- Stebler Yanik
- Steinmetz Gis\ue9le
- Stenwak Agata
- Stockholm Jette
- Stokke Bodil
- Stompel Daniel
- Stopford Cheryl
- Storch Alexander
- Stubbe Lars
- Sulek Anna
- Summers Fiona
- Sundblom Jimmy
- Svenningsson Per
- Swain Rachel
- Szczudlik Andrzej
- Szczygiel Elzbieta
- Szinwelski Michal
- Tabrizi Sarah
- Tacik Pawel
- Tard C\ue9line
- Taroni Franco
- Tataru Alina
- Taylor Anne-Marie
- Taylor Cat
- Taylor Rachel
- Tchikviladz\ue9 Maya
- Thibault-Tanchou St\ue9phanie
- Thiel Silvia
- Thomas Gareth
- Thompson Jennifer
- Thomson Aileen
- Tidswell Katherine
- Timewell Erika
- Timings Leanne
- Tir M\ue9lissa
- Tomasello Chiara
- Tonner Alison
- Torlizzi Flavia
- Torres Mar\ueda Martirio Antequera
- Toscano Jean
- Townhill Jenny
- Tranchant Christine
- Trautmann Sonja
- Trender-Gerhard Iris
- Tucci Tecla
- Tuuha Katri
- Tyvoll Hilde
- Udaeta Beatriz
- Uhrova Tereza
- Ulla Miguel
- Ullah Jasmin
- Ure Alexandra
- Valadas Anabela
- Valentine Ruth
- Van De Wyngaerde Fran\ue7oise
- Van Den Bogaard Simon J. A.
- Van Hout Monique S. E.
- Van Oostrom Joost
- Van Paemel Dominique
- Van Reijen Dimphna
- Van Vugt Jeroen P. P.
- Van Walsem Marleen
- Vandenberghe Wim
- Vangsted-Hansen Christina
- Vaughan Vivien
- Ventura Marta Fat\ue1s
- Verellen-Dumoulin Christine
- Verhoeven Marloes
- Vernon Nathan
- Verny Christophe
- Verstappen Carla
- Verstraelen Nicola
- Vezza Maurizio
- Vidal Tiphaine
- Viladrich C\ue8lia Mareca
- Vilaplana Carmen Peir\uf3
- Villa Riballo Antonio
- Villa Carolina
- Villanueva Clara
- Villanueva Marina \uc1vila
- Vingerhoets Francois
- Vinther-Jensen Tua
- Vivancos Laura
- Vogel Melanie
- Vuillaume Isabelle
- W\uf3jcik Magdalena
- Waber Mirella
- Wagner Caroline
- Wahlstr\uf6m Jan
- Wallden Tina
- Walleczek Anna Maria
- Wannepain Sandrine
- Warner Thomas
- Wasielewska Anna
- Weber Nathalia
- Weekes Rebecca
- Wehus Ragnhild
- Weindl Adolf
- Wenning Gregor
- Wermuth Lene
- Werner Cornelius J.
- Westman Laila
- Westmoreland Leann
- Weydt Patrick
- Whaite Anna
- Wi\u15bniewski Bartlomiej
- Wider Christian
- Wikstr\uf6m Birgitta
- Wild Edward
- Wild Sue
- Williams Josh
- Winkelmann Juliane
- Winkler J\ufcrgen
- Witjes-An\ue9 Marie-Noelle
- Witkowski Grzegorz
- Wolz Annett
- Wolz Martin
- Wood Josh
- Wright Abigail
- Wright Jan
- Yardumian Pam
- Yates Shona
- Youssov Katia
- Yudina Elizaveta
- Zaremba Jacek
- Zaugg Sabine Weber
- Zdzienicka Elzbieta
- Ziegler Cornelia
- Zielonka Daniel
- Zielonka Eugeniusz
- Zimmermann Marie-Agathe
- Zinzi Paola
- Ziora-Jakutowicz Karolina
- Zittel Simone
- Zucker Birgit
- Publication venue
- 'IOS Press'
- Publication date
- 01/01/2018
- Field of study
Background: People with Huntington's disease (HD) have been observed to have lower rates of cancers. Objective: To investigate the relationship between age of onset of HD, CAG repeat length, and cancer diagnosis. Methods: Data were obtained from the European Huntington's disease network REGISTRY study for 6540 subjects. Population cancer incidence was ascertained from the GLOBOCAN database to obtain standardised incidence ratios of cancers in the REGISTRY subjects. Results: 173/6528 HD REGISTRY subjects had had a cancer diagnosis. The age-standardised incidence rate of all cancers in the REGISTRY HD population was 0.26 (CI 0.22-0.30). Individual cancers showed a lower age-standardised incidence rate compared with the control population with prostate and colorectal cancers showing the lowest rates. There was no effect of CAG length on the likelihood of cancer, but a cancer diagnosis within the last year was associated with a greatly increased rate of HD onset (Hazard Ratio 18.94, p < 0.001). Conclusions: Cancer is less common than expected in the HD population, confirming previous reports. However, this does not appear to be related to CAG length in HTT. A recent diagnosis of cancer increases the risk of HD onset at any age, likely due to increased investigation following a cancer diagnosis
Clinical and genetic characteristics of late-onset Huntington's disease
- Author
- Aanonsen Nils Olaf
- Aaserud Olaf
- Abbruzzese Giovanni
- Acera Gil Maria Angeles
- Ackermann Oda
- Adarmes Astrid
- Agarwal Veena
- Agosti Chiara
- Akhtar Shahbana
- Alaerts Nick
- Alarcón María Dolores
- Albanese Alberto (ORCID:0000-0002-5864-0006)
- Allain Philippe
- Almagro Carmen Antúnez
- Almeida Manuel
- Alonso-Frech Fernando
- Alusi Sundus
- Anderson Mary
- Andersson Christian
- Andrade Carlos
- Andrew Alyson
- Andrews Thomasin
- Andrews Thomasin
- Andrich Jürgen
- Anheim Mathieu
- Anjum Uruj
- Anna Bryl Jacek Anioła
- Annic Agnès
- Antczak Jakub
- Antequera Torres María Martirio
- Antonova Victoria
- Arbelo José Matías
- Arkuszewski Michał
- Armstrong Richard
- Armstrong Richard
- Arntsen Vibeke
- Arques Penelope Navas
- Arran Natalie
- Azulay Jean-Philippe
- Baake Verena
- Babiloni Blandine
- Bachmeier Michael
- Bachoud-Lévi Anne-Catherine
- Bachoud-Lévi Anne-Catherine
- Badei Farideh
- Bailey Wendy
- Banaszkiewicz Krzysztof
- Bandettini di Poggio Monica
- Bandmann Oliver
- Barbera Miquel Aguilar
- Barker Roger A.
- Barlati Sergio
- Barral Verónica Mañanes
- Barrero Francisco
- Barrett Wendy
- Barth Katrin
- Barth Katrin
- Barthélémy Recka
- Bartoli Caterina
- Barun Nadia
- Bas Jordi
- Bascuñana Mónica
- Becanovic Kristina
- Bechtel Natalie
- Beckmann Heike
- Bek Judith
- Bellonet Marcellin
- Benaich Sandra
- Benaminov Stanislav
- Benito Dolors Moragues
- Bentivoglio Anna Rita (ORCID:0000-0002-9663-095X)
- Bentivoglio Anna-Rita
- Berglund Maria
- Berglund Måns
- Berglund Peter
- Bergmann Ulrike
- Bernal-Escudero Maravilla
- Bernard Tomáš
- Bertini Elisabetta
- Bethwaite Pamela
- Betz Sabrina
- Beuth Markus
- Bezdíček Ondřej
- Bijlsma Emilia K.
- Bioux Sandrine
- Biunno Ida
- Björnsson Elisabeth
- Bjørgo Kathrine
- Bjørnevoll Inga
- Bled Déborah
- Bliaux Evangeline
- Blin Stéphanie
- Blinkenberg Ellen Økland
- Blondeau Leily
- Boczarska-Jedynak Magdalena
- Boelmans Kai
- Bohlen Stefan
- Boissé Marie-Françoise
- Bojakowska-Jaremek Kamila
- Bojarsky Jaime Kulisevsky
- Bonelli Raphael M.
- Bonelli Raphael M.
- Bonelli Raphael M.
- Bonneau Dominique
- Boogaerts Andrea
- Boogaerts Andrea
- Borgerød Nancy
- Bos Reineke
- Bos Reineke
- Bosca Maria
- Bosredon Cecile
- Bost Marie
- Boster Sarah
- Boudali Lotfi
- Bove Francesco
- Boćwińska Dorota
- Bradbury Alyson
- Braunwarth Eva-Maria
- Brice Alexis
- Brockie Peter
- Bronzova Juliana
- Brown Pauline
- Brugada Francisco Castera
- Brugger Florian
- Bruno Stefania
- Bruun Anu
- Buchanan Lindsay
- Buck Andrea
- Buongiorno María Teresa
- Buratti Lisa
- Burguera Juan Andres
- Burgunder Jean-Marc
- Burgunder Jean-Marc
- Burgunder Jean-Marc
- Burn John
- Burrows Liz
- Busquets Núria
- Busse Monica
- Butcher Cynthia
- Bárcenas Antonio Herranz
- Böringer Regina
- Bürk Katrin
- Błaszczyk Magdalena
- Cabaret Maryline
- Calado Ana
- Calandra-Buonaura Giovanna
- Caldentey Juan García
- Caldentey Juan García
- Caldentey Juan García
- Callaghan Jenny
- Callaghan Jenny
- Callaghan Jenny
- Calmeyn Godelinde
- Calopa Matilde
- Calvas Fabienne
- Calzado Noemi
- Campolongo Antonia
- Cannella Milena
- Capellari Sabina
- Capetian Philipp
- Capodarca Selene
- Cardoso Helena
- Carette Anne-Sophie
- Carrillo Fátima
- Carrière Nicolas
- Carruesco Gemma Tome
- Casado Rocío Villagrán
- Cass Ginette
- Castagliuolo Simona
- Castaldo Anna
- Catalli Claudio
- Catena Judit López
- Cavaco Sara
- Cação Gonçalo
- Charles Perrine
- Charpentier Sébastien
- Chen Simone
- Cheriet Samia
- Chiara Piccininni
- Chu Carol
- Chu Elvina
- Chu Elvina
- Ciach-Wysocka Ewelina
- Ciesielska Anna
- Classen Serge Jaumà
- Clayton Carole
- Clenaghan Catherine
- Cleret de Langavant Laurent
- Coarelli Giulia
- Codella Valentina
- Coebergh Jan
- Coelho Miguel
- Coleman Caroline
- Come Adrien
- Compostella Silvia
- Connemann Julia
- Constant Eric
- Constantinescu Radu
- Cormio Claudia
- Corrales Koldo Berganzo
- Cortelli Pietro
- Cosgrove Jeremy
- Costa Andreia
- Costa Cristina
- Coulthard Elizabeth
- Couttier Julien
- Craufurd David
- Craven Janet
- Craven Janet
- Crooks Jenny
- Cubillo Patricia Trigo
- Cubillo Patricia Trigo
- Cubo Esther
- Curtis Adrienne
- D'Alessio Barbara
- Damásio Joana
- Davidson Lynn
- Davies Rhys
- Davison Jill
- De Bruycker Christelle
- de Die-Smulders Christine EM.
- De Gregorio Francesca
- De Michele Giuseppe
- De Nicola Annunziata
- de Raedt Sylvie
- de Souza (Keylock) Jenny
- de Tommaso Marina
- Debilly Bérengère
- Debruxelles Sabrina
- Dec Małgorzata
- Decorte Eric
- Dedichá Nadia Rodríguez
- Defebvre Luc
- Deith Catherine
- Dekker Meike
- Delabaere Helène
- Delaigue Christine
- Delfini Marie
- Delliaux Marie
- Delval Arnaud
- Delvaux Isabelle
- Demonet Jean-François
- Depelchin Alizé
- Derost Philippe
- Descals Asunción Martínez
- Destee Alain
- Dewulf-Pasz Nelly
- Di Bella Daniela
- Di Donato Stefano
- Di Giacopo Raffaella
- Di Maio Luigi
- Di Maria Emilio
- Di Renzo Martina
- Diago Elena Bellosta
- Dias Margarida
- Diercks Gabriele
- Difruscolo Olimpia
- Dipple Heather
- Dixon Kathryn
- Dixon Kathryn
- Diéguez Esther
- Doherty Karen
- Dondaine Thibaut
- Donovan John O.
- Dose Matthias
- Dougherty Andrew
- Downie Lorna
- Dramstad Elisabeth
- Dressler Dirk
- Duché Charlotte
- Duffell Allison
- Dugauquier Florence
- Duits Annelien
- Dujardin Kathy
- Dumas Eve M.
- Dunnett Stephen
- Dunnett Stephen B.
- Duport Sophie
- Dupuis Michel
- Durif Franck
- Durr Alexandra
- Dziadkiewicz Artur
- Ecker Daniel
- Ecker Daniel
- Eddy Charlotte
- Edwards Maureen
- Edwards Rachel
- Eklund Pia
- Ekwall Camilla
- El-Nimr George
- Elifani Francesca
- Ellrichmann Gisa
- Esmaeilzadeh Mouna
- Esposito Chiara
- Esposito Federica
- Eusebio Alexandre
- Evans Carole
- Ewenczyk Claire
- Fairtlough Helen
- Fannemel Madeleine
- Fasano Alfonso
- Feliz Cici
- Fenollar María del Mar
- Fernandes Joana
- Fernandez de Bobadilla Ramon
- Fernandez Cristina Melgar
- Ferraldeschi Michela
- Ferrandes Giovanna
- Ferreira Joaquim J.
- Ferreira Joaquim J.
- Ferrer Pilar Quiléz
- Figorilli Michela
- Figuerola Begoña Jeweinat
- Fillingham Kay
- Finisterra Ana Maria
- Fisher Kate
- Flamez Anja
- Fletcher Amy
- Fluchere Frédérique
- Fortuna Lorenza
- Fortunato Fernanda
- Foster Jillian
- Foustanos Isabella
- Foy Kevin
- Frades Belén
- Fraisse Sonia
- Francis Flverly
- Francisque Hélène
- Franco Giovanni
- Fredlund Gunnel
- Freire-Patino Dawn
- Frich Jan
- Frich Jan C.
- Frontali Marina
- Frontali Marina
- Frost Julie
- Fullam Ruth
- Fullam Ruth
- Fullam Ruth
- Fuller Kathleen
- Fullerton Neil
- Gago Miguel
- Gallantree Deena
- Gallassi Roberto
- Gallentree Deena
- Ganos Christos
- Ganos Christos
- Garcia-Amigot Fermin
- García de Yébenes Justo
- García Moreno José Manuel
- García Ruíz Pedro José
- García Ana
- García-Ramos García Rocío
- Garde Monica Bascuñana
- Garrett Carolina
- Gaston Itziar
- Gayde-Stephan Sabine
- Geitner Carolin
- Gelderblom Harald
- Gellera Cinzia
- Genitrini Silvia
- Genoves Camille
- Germain Véronique
- Gerrans Emily
- Gerrtiz (nee Di Pietro) Anna
- Gethin Louise
- Ghelli Elena
- Gill Paul
- Gillardin Anne-Françoise
- Gilling Mette
- Ginestroni Andrea
- Girard Carole
- Giuliano Joe
- Goerendt Ines
- Gogol (formerly Kalbarczyk) Anna
- Gohier Bénédicte
- Goizet Cyril
- Golding Charlotte
- Golding Charlotte
- Gomez Esteban Juan Carlos
- González Amaia
- González Sonia
- Gonçalves Alexandra
- Good Jean-Marc
- Goodman Anna
- Gorzkowska Agnieszka
- Gorzolla Heike
- Gosling (nee Brown) Stefanie
- Goudie David
- Gowers Lesley
- Grabska Natalia
- Guedes Leonor Correia
- Guedes Leonor Correia
- Guenam Aicha
- Guia Dolors Badenes
- Guidubaldi Arianna
- Guimarães Joana
- Guisasola Luis Menéndez
- Gunner Kerry
- Guyant-Maréchal Lucie
- Guzman Natalie Valle
- Guérid Marie-Anne
- Göller Marie-Lousie
- Göpfert Nicole
- Gørvell Per F.
- Haggag Kathrine
- Haider Salman
- Haig-Brown Diane
- Haig-Brown Diane
- Hallam Caroline
- Hamer Stephanie
- Hamer Stephanie
- Hametner Eva-Maria
- Handley Olivia J.
- Handley Olivia J.
- Hannequin Didier
- Hannier Véronique
- Harding Alison
- Hare Marianne
- Hare Marianne
- Harris Kayla
- Harrison David
- Harrison Kaye
- Harrower Timothy
- Harrower Timothy
- Hartikainen Paivi
- Haug Marte Gjøl
- Hauge Erik
- Hayward Beverley
- Hayward Elaine
- Hecht Karen
- Heiberg Arvid
- Heiberg Arvid
- Heinicke Walburgis
- Held Christine
- Held Christine
- Hensman Davina
- Hepperger Caroline
- Hermoso Fátima Damas
- Hernanz Laura Casas
- Herranhof Brigitte
- Herrera Carmen Durán
- Herrmann Lennard
- Heywood Melanie
- Hidding Ute
- Hiivola Heli
- Hill Susan
- Hjermind Lena
- Ho Aileen
- Ho Carrie
- Hobson Emma
- Hoffmann Rainer
- Hofstetter Nina
- Hogenboom Marye
- Holas Christiane
- Holl (formerly Hödl) Anna
- Holmes Katrina
- Hopes Lucie
- Horta Andrea
- Horta Andrea
- Hotter Anna
- Howard Liz
- Hughes Max
- Hunger Ulrike
- Hunt Sarah
- Huson Susan
- Hussain Hasina
- Hussl Anna
- Hvalstedt Carina
- Hyppönen Hannele
- Hölzner Eva
- Høsterey-Ugander Ulrika
- Ialongo Tamara
- Ignatius Jaakko
- Illarioshkin Sergey
- Illarioshkin Sergey
- Illmann Torsten
- Ireland Jane
- Irvine Sarah
- Jacek (formerly Rödig
- Jachinska Katarzyna
- Jack Roisin
- Jacobs Milou
- Jacobsen Oda
- Jacopini Gioia
- Jacopini Gioia
- Jameau Laetitia
- Jamieson Stuart
- Jamrozik Zygmunt
- Janik Piotr
- Januário Cristina
- Jaramillo Javier Abril
- Jasińska-Myga Barbara
- Jauffret Céline
- Jesús Silvia
- Johannessen Cecilie Haggag
- Johansson Anders
- Johns Nicola
- Johnson Liz
- Jones Lesley
- Jones Mary
- Jones Una
- Jourdain Séverine
- Jung Hans H.
- Jurgens Caroline
- Justo Damian
- Jääskeläinen Outi
- Júlio Filipa
- Kaczmarczyk Aleksandra
- Kaelin Alain
- Kaiserova Michaela
- Kajula Outi
- Kaminska Anna
- Kaminski Barbara
- Kammel Gerit
- Kampstra Anne
- Kapfhammer Hans-Peter
- Kassar Abdulrahman
- Kavalier Fred
- Kazoka Mbombe
- Kennedy (nee Smith) Karen
- Kesse Andrea
- Keys Liane
- Khalil Hanan
- Khasanova Diana
- Kipps Christopher
- Klebe Stephan
- Klebe Stephan
- Klempir Jiri
- Klempíř Jiří
- Klempířová Olga
- Klimberg Aneta
- Klooster Jesper
- Klyushnikov Sergey
- Knight Caroline
- Koehli Jessica
- Kohl Zacharias
- Koivisto Susana Pro
- Koivisto Susana Pro
- Komati Suresh
- Konkel Agnieszka
- Kopishinskaya Svetlana
- Koppers Kerstin
- Koppitz Michael
- Korotysh Maria
- Kosinski Christoph Michael
- Kozay Christina
- Kramer Bianca
- Kraus Alison
- Kraus Alison
- Kraus Peter
- Krawczyk Malgorzata
- Kremer Berry
- Kremer Berry
- Krishnamoorthy Ashok
- Krysa Wioletta
- Krystkowiak Pierre
- Krystkowiak Pierre
- Kubowicz Ewelina
- Kurbatov Sergey
- Kwiecinski+ Hubert
- Kärppä Mikko
- Kłodowska – Duda Gabriela
- Ladurner Gunther
- Lafoucrière Danielle
- Lagha-Boukbiza Ouhaid
- Lahiri Nayana
- Lahiri Nayana
- Laing Hana
- Lamanna Claudia
- Lambeck Johann
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- van de Wyngaerde Françoise
- van den Bogaard Simon J. A.
- van Hout Monique S. E.
- van Kuijk Sander MJ.
- van Oostrom Joost
- Van Paemel Dominique
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- van Vugt Jeroen P. P.
- van Walsem Marleen
- van Walsem Marleen R.
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- Zaremba
- Zaremba Jacek
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- Zdzienicka Elzbieta
- Zea Sevilla Maria Ascension
- Ziegler Cornelia
- Zielonka Daniel
- Zielonka Daniel
- Zielonka Eugeniusz
- Zimmermann Marie-Agathe
- Zinzi Paola
- Zinzi Paola
- Zinzi Paola
- Ziora-Jakutowicz Karolina
- Zittel Simone
- Zouitina Yassine
- Zucker Birgit
- Åman Jaana
- Østern Rune
- Šašinková Pavla
- Šenkárová Zuzana
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: The frequency of late-onset Huntington's disease (>59 years) is assumed to be low and the clinical course milder. However, previous literature on late-onset disease is scarce and inconclusive. Objective: Our aim is to study clinical characteristics of late-onset compared to common-onset HD patients in a large cohort of HD patients from the Registry database. Methods: Participants with late- and common-onset (30–50 years)were compared for first clinical symptoms, disease progression, CAG repeat size and family history. Participants with a missing CAG repeat size, a repeat size of ≤35 or a UHDRS motor score of ≤5 were excluded. Results: Of 6007 eligible participants, 687 had late-onset (11.4%) and 3216 (53.5%) common-onset HD. Late-onset (n = 577) had significantly more gait and balance problems as first symptom compared to common-onset (n = 2408) (P <.001). Overall motor and cognitive performance (P <.001) were worse, however only disease motor progression was slower (coefficient, −0.58; SE 0.16; P <.001) compared to the common-onset group. Repeat size was significantly lower in the late-onset (n = 40.8; SD 1.6) compared to common-onset (n = 44.4; SD 2.8) (P <.001). Fewer late-onset patients (n = 451) had a positive family history compared to common-onset (n = 2940) (P <.001). Conclusions: Late-onset patients present more frequently with gait and balance problems as first symptom, and disease progression is not milder compared to common-onset HD patients apart from motor progression. The family history is likely to be negative, which might make diagnosing HD more difficult in this population. However, the balance and gait problems might be helpful in diagnosing HD in elderly patients
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
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- Winter Des
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- Wondoh Paul M.
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- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
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- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
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- Yang P Zichu
- Yanikoglu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
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- Yenli Edwin
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- Zabiyaka Mikhail
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- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdağ Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
- Ayyad Rawan
- Azevedo José
- Azodo Ijeoma
- Azzubia Joma
- B L Ashika
- Ba Mouhamadou Bachir
- Babaa Basheer
- Babirye Lilian
- Bacic Ivan
- Badr Esraa Tarek
- Badr Helmy
- Badran Abdul
- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
- Bajilan Mohammad
- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
- Bakoleas Panagiotis
- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
- Bamaca Ixcajoc Elvis Benjamin
- Banaz Tuba
- Banda Bitiel
- Banglani Muntaha
- Bani Hani Farah
- Bani hani Mohammad
- Bani hani Zeina
- Baniowda Muath
- Banks Alexander
- Bannister Sharon
- Baranyai Zsolt
- Barati Nastaran
- Barbosa Camacho Francisco José
- Barbosa José
- Bardos David
- Barendegere Venerand
- Barghuthi Lutfi
- Barhoush Ola
- Barnes Nicole
- Baronio Gianluca
- Barreda Zelaya Lilian Elizabeth
- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
- Bartosiak Katarzyna
- Basarab Maksym
- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
- Bath Michael
- Beattie Miriam
- Bedada Alemayehu Ginbo
- Belais Fanny
- Belal qadomi Asef
- Belev Nikolay
- Belli Andrea
- Beltrán de Heredia Juan
- Belvedere Angela
- Ben Dallah Najah
- Ben Saoud Abdulsalam Ali
- Bengur Fuat Baris
- Benkabbou Amine
- Benke Marton
- Benyaiche Chaymae
- Bergeat Damien
- Bernstein Mitchell
- Beshtawi Doha
- Besli Sevval
- Beuran Mircea
- Bhandare Manish
- Bhangu Aneel
- Bhatti Muhammad Iqbal
- Bianchini Stefania
- Bianco Francesco
- Bibas Fatma
- Biccard Bruce M
- Bielosludtsev Oleksii
- Bienfait Mumbere
- Billy Matthew
- Bin Mohamad Sithik Muhammad Navid
- Binetti Margherita
- Bingham Janne
- Bird Jonathan
- Birindelli Arianna
- Birks Sarah
- Birutis Justas
- Björklund Ida
- Blackman Brighid
- Blackwell James
- Blanco-Colino Ruth
- Blok Robin
- Blomme Nina
- Blomqvist Malin
- Blunnie Eimear
- Bnhameida Sondos
- Boddy Alex
- Bodur Muhammed Selim
- Boereboom Catherine
- Bogusevicius Algirdas
- Bolzonaro Elisa
- Bonavina Luigi
- Bondurri Andrea
- Bonghaseh Divine Tim
- Bono Lorenzo
- Borda-Luque Giuliano
- Borg Elaine
- Borghi Felice
- Borham Hala
- Borowski David W
- Bortolasi Luca
- Bosch Marina
- Bosire Fridah
- Bossi Daniela
- Botes Azel
- Bouaziz Hanen
- Bougard Heather
- Boutall Adam
- Boutros Marylise
- Bouzaiene Hatem
- Boyce Stephen
- Boyd-Carson Hannah
- Boyle Connor
- Braccio Bartolomeo
- Bradulskis Saulius
- Brata Santi Yuanita
- Bratu Matei Razvan
- Brito Diana
- Brocklehurst Peter
- Brooker Ethan
- Brooks Savannah
- Brown James
- Bruce Eilidh
- Bsisu Isam
- Bua Emmanuel
- Bucci Luigi
- Budd Gabrielle
- Budzyński Andrzej
- Budzyński Piotr
- Bujda Michele
- Bulaya Anadi
- Bullock Cameron
- Burger Sule
- Burgu Gökçen
- Burke Daniel
- Burman Shivang
- Bury Pawel
- Busuttil Zachary
- Butt Eman
- Buxant Frederic
- Buzaite Kristina
- C S Archana
- Caballero Díaz Yurena
- Cabrera Rivera Paulo Andrés
- Cagigas Fernandez Carmen
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- Tutino Roberta
- Tuynman Jurriaan
- Tyselskiy Volodimir
- Tzovaras George
- Tüfek Ozan yavuz
- Türkyilmaz Serdar
- Ubartas Nerijus
- Ubiali Paolo
- Ugoletti Lara
- Ugolini Giampaolo
- Uluşahin Mehmet
- Umenze Franklin
- Umoke Ifeanyi
- Underwood Charlotte
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- Urbieta Aitor
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- Uribe Valencia Andres
- Usai Antonella
- Usta Arif
- Utrilla Fornals Alejandra
- Uwakunda Carine
- Uy Gemma Leonora
- Uysal Muhammed
- V Sushmita
- Valente da Costa Ana
- Valle Aranda Yener Cristyell
- van Berge Henegouwen Mark
- van Berge Henegouwen Mark I.
- van Dalen Anne Sophie
- Van Der Merwe Lisa Hannah
- van Geloven Aaw
- Van hentenryck Marie
- van Praag Elise Maria
- van Schilt Kaz
- Van Straten Stephanie
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- Varol Ecenur
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- Vaughan-Shaw Peter G
- Vaysse Charlotte
- Vazquez Fernandez Andrea
- Veale Kelly
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- Venskutonis Donatas
- Venturelli Paolina
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- Verdaguer Tremolosa Mireia
- Vergara María
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- Vieira Barros Aldo
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- Warwicker Sean
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- Watts Daniel
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- Wierdak Mateusz
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- Wilguens Lartigue Jean
- Willemin Melissa
- Williams Christopher Yee Khang
- Wills Vanessa
- Wilson Karim
- Wilson Michael
- Wimmer Kerstin
- Windsor John
- Wineberg Devorah
- Winiarski Marek
- Winoto Hadi
- Winter Beatty Jasmine
- Winter Des
- Wisal Maham
- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
- Wong Lai Fen
- Wong Michael Pak-Kai
- Wong Sui-Weng
- Wong Tsz Lun Ernest
- Wood Lauren
- Woon-Shoo-Tong Xiao-Ming Sarah
- Wren Sherry
- Wuraola Funmilola
- Xanthopoulou Georgia
- Yabut Kenneth
- Yacoub Aseel
- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
- Yalçinkaya Ali
- Yang P Zichu
- Yanikoğlu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürşat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
- Yepez Raul
- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
- Ylatoma Díaz Edgar Alcides
- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
- Younes Eman
- Younes Maha
- Yousry Basant
- Yozgatli Tahir Koray
- Yu Kristin
- Yue Sum Yu Pansy
- Yunes Asmaa
- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- Abellán Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Özlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia González
- Aleem Muhammad
- Alegre Inês
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz Amorós
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-Díez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado Fabíola
- Amador Cristina García
- Amanullah Nazli
- Amaral Hélida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- Andrés Beatriz Díaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- Aşkar Ahmet
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia Fernández
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
- Bains Lovenish
- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
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- Balfour James
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- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
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- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
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- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel Sánchez
- Bayhan Zülfü
- Bayo José Manuel Muros
- Bayón Raquel Álvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
- Belay Million
- Belev Nikolay
- Bellato Vittoria
- Beltrán de Heredia Juan
- Belvedere Angela
- Benetti Emilio
- Benetti Sara
- Bengueddach Aicha
- Benjelloun El Bachir
- Benkabbou Amine
- Bennett James
- Bensafir Salim
- Bergamini Carlo
- Bernotaite Vlada
- Beron Reinaldo Isaacs
- Bethune Robert
- Bezede Cosmin
- Beznosenko Andriy
- Bhangu Aneel
- Bhargava Aman
- Bhat Rama Rani Krishna
- Bianchi Romina
- Bianco Francesco
- Bigoni Irene
- Binetti Margherita
- Bintintan Vasile
- Biondi Alberto
- Biondo Santino Antonio
- Bisgin Tayfun
- Bisheet George
- Bissett Ian
- Biswas Jyotirmoy
- Blackwell Sue
- Blanco Pablo
- Blanco Raquel Ríos
- Blanco-Colino Ruth
- Blasco Laura Fraile
- Blazquez-Martin Alma
- Bobadilla Billy Jimenez
- Bocancia Raluca
- Boccia Giuseppe
- Bogatikov Alexander
- Bolanle Olajide Edward
- Bomfa-Barbosa Alysson
- Bompou Effrosyni
- Bonardello Michela
- Bonci Eduard-Alexandru
- Bordom Daniel Osei
- Borges Filipe
- Borghi Felice
- Boschiero Matheus Negri
- Bose Bodhisattva
- Bouchagier Konstantinos
- Boudjenan-Serradj Nabil
- Boudoux Sabrina
- Bourazani Maria
- Boyce Stephen
- Bozbiyik Osman
- Bracale Umberto
- Brachini Gioia
- Bradulskis Saulius
- Brainsa Eneida
- Brandström Gustav
- Braumille Markus
- Bravo Ana Minaya
- Bravo Raquel
- Bredikhin Mikhail
- Brito Noelia
- Bruni Andrea
- Buccianti Piero
- Buchs Nicolas
- Buchwald Pamela
- Budnikova Ina
- Budrikienė Rima
- Buey Lourdes
- Buijs Louis
- Buleje Jorge Alejandro Benavides
- Burlov Nikita
- Butt Anam
- Byshetty Rajendar
- Bywater Edward
- Bzikha Ilham
- Bánky Balázs
- Bælum Jens Kristian
- Caballero-Delgado Javier
- Cabrera Claudia
- Cafranga Estíbaliz Gutiérrez
- Cagnazzo Federica
- Calabria Mariangela
- Calabro' Marcello
- Caliendo Domenico
- Calin Camelia
- Caliskan Cemil
- Callan Rory
- Callari Cosimo
- Caltea Mihaela
- Calvo Almudena Castro
- Camacho Amparo
- Cammarata Francesco
- Campanati Renato
- Campanelli Michela
- Campbell Marion
- Canals Lucía Otazu
- Canda Aras Emre
- Cano-Matias Auxiliadora
- Cao Victor Hugo Bruno
- Capolupo Gabriella Teresa
- Cappiello Antonio
- Capuano Marianna
- Capusan Alina
- Carannante Filippo
- Carbone Ludovico
- Cardelli Stefano
- Carden Claire
- Cardoso Diogo
- Caricato Marco
- Carlin Patricia Saez
- Carlini Massimo
- Carlos Sandra
- Carneros Virginia Jimenez
- Carosso Fabio
- Caroço Teresa Vieira
- Carpelan Anu
- Carpenter Holly
- Carrascosa-Morales Irene
- Carrie Augusto
- Carrizo Claudia
- Carta Giuseppina
- Carvalho Alexandre
- Carvello Michele
- Casanova Daniel
- Cascais Raquel
- Cassia Gabriela
- Castaldi Antonio
- Castaño Renata
- Castiglioni Simone
- Castillo Enrique Roca
- Castro Marta Cuartero
- Catalano Pablo
- Cato Liam
- Caz Esra
- Cebolla Elena Sagarra
- Cecchini Ilaria
- Celdrán Rebeca González
- Celik Hale Kefeli
- Ceretti Andrea Pisani
- Ceron Silvia Ferrer
- Cervellera Maurizio
- Cervone Carmela
- Chacko Anil
- Chandrasinghe Pramodh
- Charakopoulou Alexandra
- Chardalias Leonidas
- Chaturvedi Arun
- Chatzikomnitsa Paraskevi
- Chaudhari Abhishek
- Chaudhry Sanjay
- Chawla Tabish
- Chee Corissa
- Chen Nevin
- Cheng Kuang I
- Chiarugi Massimo
- Chisthi Meer
- Chitnis Abhishek
- Chitul Andrei
- Chmielewski Gaspard
- Cholewa Hanna
- Chornet Marta Roselló
- Chowdhary Manish
- Chowdhury Sharfuddin
- Chowdhury Sharfuddin M
- Chowdri Nisar
- Christensen Peter
- Christodoulidis Grigorios
- Chrysos Emmanuel
- Chua Lorna
- Chubukova Natlia
- Chung Jun Seong
- Church Robert
- Chwat Carina
- Ciabattari Paula
- Cianchi Fabio
- Cianci Pasquale
- Ciccarese Angelo Antonio
- Ciftci Ahmet Burak
- Cigagna Luca
- Cini Charles
- Ciotarla Danut Constantin
- Cirocchi Nicholas
- Ciubotaru Cezar
- Ciulli Cristina
- Ck Harikumar
- Clark Thomas
- Clarke Nicola
- Coccolini Federico
- Codes Lina
- Coelho Ana Margarida
- Cois Alessandro
- Coladonato Massimiliano
- Colak Elif
- Coldwell Chris
- Collins Jen
- Colombo Francesco
- Colás-Ruiz Enrique
- Conceição Luis
- Conde Juan Guillermo Ais
- Connolly Lewis
- Conversano Ivana
- Convertini Ornella
- Cook Esther
- Cooke Fiachra
- Coppolino Francesco
- Coratti Francesco
- Cordeiro Lisbete
- Correia Angela
- Correia Débora
- Cortes Bruno Giusti Werneck
- Cortés Guillermo Felipe Valderas
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- Costa Sílvia
- Cour Kenn La
- Crabtree Nicholas
- Creavin Ben
- Cremonini Camilla
- Crescentini Giacomo
- Cricrì Michele
- Crisan Dana
- Cristian Daniel
- Croce Gianni Di
- Cruz Isabela
- Cucinotta Eugenio
- Cuichan Marco Vinicio Yugsi
- Cullinane Carolyn
- Cuneo Davide
- Cunha Miguel
- Curbelo Jacqueline
- Curcio Silvia
- Curro Giuseppe
- Currà Maria Cristina
- Currás Rosana Pérez
- Custódio Pedro
- Cutellè Clelia
- Czarnecki Roman
- D'Angelo Salvatore
- D'Ugo Stefano
- da Luz Magda
- da Silveira Sete Alexandre
- Dainius Edvinas
- Dalton Richard
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- Danassi Despoina
- Danelli Piergiorgio
- Danial Aghyad Kudra
- Daniels Ian R
- Daniyan Muhammad
- Danna Riccardo
- Danys Donatas
- Dardanov Dragomir
- Daryanani Deepu
- Dassanayake Vihara
- Daugėla Edvardas
- Dauri Mario
- Davidovskaja Larisa
- Davies Emma
- Davis Cian
- Dawson Brett E
- Dawson Carmel
- de Andrés-Asenjo Beatriz
- de Deken Julie
- de Franciscis Silvia
- de Kort Chantal
- de La Plaza Llamas Roberto
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- de León Rendón Jorge Luis
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- de Miranda Silvestre Simone Chaves
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- de Oliveira Flávia Gomes
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- de Souza Pires Bruno Lucena
- de Stefano Mauro
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- Dedeu-Bastardas Imma
- Degiuli Maurizio
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- Del Olmo Maria Inmaculada Ureña
- Del Pueblo Cristina Sanchez
- Del-Rio-Lafuente Francisco-Javier
- Delgado Eduardo
- Delgado Marina
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- Diez-Alonso Manuel
- Dijan Emilio
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- Dimitriou Nikoletta
- Dimitrov Dobromir
- Dimitrova Slavina
- Dimofte Mihail-Gabriel
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- Dominioni Tommaso
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- Doniquian Alejandro Marcelo
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- Dos Santos Marco Antônio Miranda
- Dos Santos Maria Beatriz Alves
- Douba Zain
- Drissi Farouk
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- Earley Helen
- Ebdewi Hamdi
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- Egwuonwu Ochonma Amobi
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- El Ahmadi Brahim
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- Eldakroury Israa
- Eldin Sami Jalal
- Elena Fanti
- Elfallal Ahmed
- Elfeki Hossam
- Elhadi Muhammed
- Elisiario Luisa
- Ellebæk Mark Bremholm
- Elmore Ugo
- Elrefai Mohamad
- Elshami Mohamedraed
- Emar Mohammed
- Emegoakor Chiemelu
- Emhareb Abdalla
- Emile Sameh
- en Siew Bei
- Ene-Cocis Mihaela-Valentina
- Eng Stanley Chee Ren
- Eraslan Huseyin
- Erdmann Thomas Rolf
- Erginöz Ergin
- Ergün Sefa
- Eriksen Niels Damgaard
- Erturk Candeniz
- Espin-Basany Eloy
- Espinha Daniela Roncoletta
- Espino Julieta
- Espino Pablo Calvo
- Esposito Giuseppe
- Esposito Rosario
- Espí-Macías Alejandro
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- Yoldas Tayfun
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- Yoshino Kenji
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- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
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- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Álvarez-Llano Laura
- Ângelo Miguel Duarte
- ÓSullivan Sara Nuñez
- Özçelik Mehmet Faik
- Ćoza Ivo
- Şanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)