A daydreaming consumer: Evaluating the impact of social media advertising content on ‘insta’ purchasing

As brands today are adapting to the growing popularity of social media sites, consumers are becoming more and more absorbed in the content they are exposed to. For brands, it is important to understand how the content they share influences consumer buying patterns and how they contribute to consumers’ daydreaming states. This study investigates daydreaming with new conceptualisation within a digital context. It explores the relationships between social media content and its ability to transmit consumers into a daydreaming state, whilst investigating the impact this has on impulsive purchasing. This as a result presents original findings which can help brands understand new relationships between social media content and consumer behaviour. Existing literature has been found to explore daydreaming on a conceptual level and there has been vast investigation into impulsive purchasing; however, there is no literature that directly measures daydreaming in a social media context, nor is there contribution that combines the two. Thus, this research aims to close this gap in research, where academic literature is lacking. This research adopted a deductive approach, using an online quasi-experimental survey. Analysis confirmed the conceptualisation of daydreaming to be valid and concluded that social media content type does not play a role in transmitting consumers into a daydreaming state. Daydreaming was found to be the mediator between social media content and impulsive purchasing, with the relationship between daydreaming and impulsive purchasing found to be significant. Noticeable differences were established in the daydreaming simulation of impulsive purchasing, with escapism being more significant for the male sample and imagination holding more weight for the female sample. The findings have been able to produce valuable insight into daydreaming within the social media context, which should be addressed by brands to engage a suitable social media strategy

A sub-product construction of Poincare-Einstein metrics

Given any two Einstein (pseudo-)metrics, with scalar curvatures suitably related, we give an explicit construction of a Poincar\'e-Einstein (pseudo-)metric with conformal infinity the conformal class of the product of the initial metrics. We show that these metrics are equivalent to ambient metrics for the given conformal structure. The ambient metrics have holonomy that agrees with the conformal holonomy. In the generic case the ambient metric arises directly as a product of the metric cones over the original Einstein spaces. In general the conformal infinity of the Poincare metrics we construct is not Einstein, and so this describes a class of non-conformally Einstein metrics for which the (Fefferman-Graham) obstruction tensor vanishes.Comment: 23 pages Minor correction to section 5. References update

Prevalence of asthma-triggering drug use in adults and its impact on asthma control

BackgroundThe use of asthma-triggering drugs (ATDs) is a major factor in poor asthma control (PAC), which can be either uncontrolled or partially controlled. ATDs include angiotensin-converting enzyme (ACE) inhibitors, β-blockers, aspirin, and nonsteroidal anti-inflammatory drugs (NSAIDs).AimsTo measure the prevalence of ATD use in adult asthmatics and their control levels.MethodsThis is a one-year cross-sectional study (starting March 2016). A sample of 173 adult asthmatics (mean age: 44±16 years) was enrolled from five primary care centres in Jeddah city (Saudi Arabia). Asthmatics were clinically diagnosed according to the British Thoracic Society’s asthma guidelines. Chronic obstructive pulmonary disease was excluded by reversibility (i.e., symptom improvement after using asthma drugs). The four questions about asthma control from the Global Initiative for Asthma’s 2016 guidelines were translated to Arabic, photos and names of ATDs available in local pharmacies were collected, and a questionnaire was drafted. The questionnaire was presented to adult asthmatics by medical students during a personal interview. Data were statistically analysed using SPSS.ResultsFifty percent of the adult asthmatics who used ATDs had badly controlled asthma: 31 per cent uncontrolled and 19 per cent partially controlled. Of the patients who took ATDs, 97 per cent had used several ATDs for extended periods of time without any warnings from health professionals. In order of prevalence, aspirin, ACE inhibitors, other NSAIDs, and β-blockers were the most common ATDs used.ConclusionATDs are a major cause of PAC. ATD use is extensive and often goes unnoticed. The present findings highlight the low awareness of health professionals about the undesirable effects of ATDs on asthma control. This problem needs to be resolved by regular and continuous asthma health educational courses. During clinic visits, health professionals should inquire about ATD use, discontinue them, and offer an alternative. This simple action could markedly improve asthma control

Tryptophan and Non-Tryptophan Fluorescence of the Eye Lens Proteins Provides Diagnostics of Cataract at the Molecular Level

The chemical nature of the non-tryptophan (non-Trp) fluorescence of porcine and human eye lens proteins was identified by Mass Spectrometry (MS) and Fluorescence Steady-State and Lifetime spectroscopy as post-translational modifications (PTM) of Trp and Arg amino acid residues. Fluorescence intensity profiles measured along the optical axis of human eye lenses with age-related nuclear cataract showed increasing concentration of fluorescent PTM towards the lens centre in accord with the increased optical density in the lens nucleolus. Significant differences between fluorescence lifetimes of “free” Trp derivatives hydroxytryptophan (OH-Trp), N-formylkynurenine (NFK), kynurenine (Kyn), hydroxykynurenine (OH-Kyn) and their residues were observed. Notably, the lifetime constants of these residues in a model peptide were considerably greater than those of their “free” counterparts. Fluorescence of Trp, its derivatives and argpyrimidine (ArgP) can be excited at the red edge of the Trp absorption band which allows normalisation of the emission spectra of these PTMs to the fluorescence intensity of Trp, to determine semi-quantitatively their concentration. We show that the cumulative fraction of OH-Trp, NFK and ArgP emission dominates the total fluorescence spectrum in both emulsified post-surgical human cataract protein samples, as well as in whole lenses and that this correlates strongly with cataract grade and age

Multistatic micro‐Doppler radar feature extraction for classification of unloaded/loaded micro‐drones

This paper presents the use of micro-Doppler signatures collected by a multistatic radar to detect and discriminate between micro-drones hovering and flying while carrying different payloads, which may be an indication of unusual or potentially hostile activities. Different features have been extracted and tested, namely features related to the Radar Cross Section of the micro-drones, as well as the Singular Value Decomposition (SVD) and centroid of the micro-Doppler signatures. In particular, the added benefit of using multistatic information in comparison with conventional radar is quantified. Classification performance when identifying the weight of the payload that the drone was carrying while hovering was found to be consistently above 96% using the centroid-based features and multistatic information. For the non-hovering scenarios classification results with accuracy above 95% were also demonstrated in preliminary tests in discriminating between three different payload weights

The Maunder minimum (1645-1715) was indeed a grand minimum: a reassessment of multiple datasets

Aims. Although the time of the Maunder minimum (1645–1715) is widely known as a period of extremely low solar activity, it is still being debated whether solar activity during that period might have been moderate or even higher than the current solar cycle (number 24). We have revisited all existing evidence and datasets, both direct and indirect, to assess the level of solar activity during the Maunder minimum. Methods. We discuss the East Asian naked-eye sunspot observations, the telescopic solar observations, the fraction of sunspot active days, the latitudinal extent of sunspot positions, auroral sightings at high latitudes, cosmogenic radionuclide data as well as solar eclipse observations for that period. We also consider peculiar features of the Sun (very strong hemispheric asymmetry of the sunspot location, unusual differential rotation and the lack of the K-corona) that imply a special mode of solar activity during the Maunder minimum. Results. The level of solar activity during the Maunder minimum is reassessed on the basis of all available datasets. Conclusions. We conclude that solar activity was indeed at an exceptionally low level during the Maunder minimum. Although the exact level is still unclear, it was definitely lower than during the Dalton minimum of around 1800 and significantly below that of the current solar cycle #24. Claims of a moderate-to-high level of solar activity during the Maunder minimum are rejected with a high confidence level

Hydroimidazolone Modification of the Conserved Arg12 in Small Heat Shock Proteins: Studies on the Structure and Chaperone Function Using Mutant Mimics

Methylglyoxal (MGO) is an α-dicarbonyl compound present ubiquitously in the human body. MGO reacts with arginine residues in proteins and forms adducts such as hydroimidazolone and argpyrimidine in vivo. Previously, we showed that MGO-mediated modification of αA-crystallin increased its chaperone function. We identified MGO-modified arginine residues in αA-crystallin and found that replacing such arginine residues with alanine residues mimicked the effects of MGO on the chaperone function. Arginine 12 (R12) is a conserved amino acid residue in Hsp27 as well as αA- and αB-crystallin. When treated with MGO at or near physiological concentrations (2–10 µM), R12 was modified to hydroimidazolone in all three small heat shock proteins. In this study, we determined the effect of arginine substitution with alanine at position 12 (R12A to mimic MGO modification) on the structure and chaperone function of these proteins. Among the three proteins, the R12A mutation improved the chaperone function of only αA-crystallin. This enhancement in the chaperone function was accompanied by subtle changes in the tertiary structure, which increased the thermodynamic stability of αA-crystallin. This mutation induced the exposure of additional client protein binding sites on αA-crystallin. Altogether, our data suggest that MGO-modification of the conserved R12 in αA-crystallin to hydroimidazolone may play an important role in reducing protein aggregation in the lens during aging and cataract formation

Guiding principles for rewilding

There has been much recent interest in the concept of rewilding as a tool for nature conservation, but also confusion over the idea, which has limited its utility. We developed a unifying definition and 10 guiding principles for rewilding through a survey of 59 rewilding experts, a summary of key organizations’ rewilding visions, and workshops involving over 100 participants from around the world. The guiding principles convey that rewilding exits on a continuum of scale, connectivity, and level of human influence and aims to restore ecosystem structure and functions to achieve a self-sustaining autonomous nature. These principles clarify the concept of rewilding and improve its effectiveness as a tool to achieve global conservation targets, including those of the UN Decade on Ecosystem Restoration and post-2020 Global Biodiversity Framework. Finally, we suggest differences in rewilding perspectives lie largely in the extent to which it is seen as achievable and in specific interventions. An understanding of the context of rewilding projects is the key to success, and careful site-specific interpretations will help achieve the aims of rewilding