2,932 research outputs found

    Three Errors in the Substance View's Defense

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    According to the theory of intrinsic value and moral standing known as the ā€œsubstance view,ā€ all human beings have intrinsic value, full moral standing and, with these, a right to life. The substance view has been defended by numerous contemporary philosophers who use the theory to argue that the standard human fetus has a right to life and, ultimately, that abortion is prima facie seriously wrong. In this paper, I identify three important errors committed by some of these philosophers in their defense of the theory---what I refer to as the ā€œextratheoretical-proposition error,ā€ ā€œquantitative-differences error,ā€ and ā€œnon-normative-answer errorā€---and conclude that these errors render their defense inadequate

    A Defense of Abortion

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    This is a review of David Boonin's A Defense of Abortion (Cambridge University Press, 2002)

    Prostitution & Instrumentalization

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    Is prostitution immoral? Various philosophers have put forward arguments for thinking so, one of the most notable being that, by engaging in sexual activity with someone for payment, the prostitute instrumentalizes himself or herself. In this paper, I identify two meanings of "instrumentalize" and, with them, two versions of the instrumentalization argument for the immorality of prostitution. I then critique each version of the argument

    An Argument for the Prima Facie Wrongness of Having Propositional Faith

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    W. K. Clifford famously argued that it is ā€œwrong always, everywhere and for anyone, to believe anything upon insufficient evidence.ā€ Though the spirit of this claim resonates with me, the letter does not. To wit, I am inclined to think that it is not morally wrong for, say, an elderly woman on her death bed to believe privately that she is going to heaven even if she does so on insufficient evidenceā€”indeed, and lest there be any confusion, even if the woman herself deems the evidence for her so believing to be insufficient. After all, her believing so does not appear to endanger, harm, or violate the rights of anyone, nor does it make the world a worse place in a significant, if any, way. That Clifford might have put too fine a point on the matter, however, does not entail that there are no conditions under which it is wrong to believe something upon insufficient evidence. In this paper, I argue that, in cases where believing a proposition (read: believing a proposition to be true) will affect others, it is prima facie wrong to have propositional faithā€”for present purposes, to believe the proposition despite deeming the evidence for oneā€™s believing to be insufficientā€”before one has attempted to believe the proposition by proportioning oneā€™s belief to the evidence

    What Will We Do? Well, What Have We Done?

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    This is a review of Anita Guerrini's Experimenting with Humans and Animals: From Galen to Animal Rights (Johns Hopkins University Press, 2003)

    Anthology and Absence: The Post-9/11 Anthologizing Impulse

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    The decade after the attacks of 9/11 and the fall of the World Trade Center saw a proliferation of New York-themed literary anthologies from a wide range of publishers. With titles like Poetry After 9/11, Manhattan Sonnet, Poems of New York, Writing New York, and I Speak of the City, these texts variously reflect upon their own post-9/11 plurivocality as preservative, regenerative, and reconstructive. However, the work of such anthologies is more complex than filling with plurivocality the physical and emotional hole of Ground Zero. These regional collections operate on the dilemma of all anthologies: that between collecting and editing. Every anthology, and every anthologist, negotiates the relationship between what is present and what is missing. In light of some of the emerging and established scholarship on the history of the English-language anthology, this article reads closely the declarative paratexts and the silent but equally powerful canonical choices of several different post-9/11 poetry anthologies. In so doing, the article comes to suggest the ways the anthologyā€™s necessary formal incorporation of absence and presence, rather than its plurivocality alone, connects collections of New Yorkā€™s literature to the fraught discourse of memorialization and rebuilding at the site of the World Trade Center

    Fractionation of fluorine, chlorine and other trace elements during differentiation of a tholeiitic magma

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    Trace element variation during magmetic differentiation of tholeiitic rock sample from Tasmania - chlorine and fluorine in hydroxyl lattice site

    Computational analysis of the LRRK2 interactome.

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    LRRK2 was identified in 2004 as the causative protein product of the Parkinson's disease locus designated PARK8. In the decade since then, genetic studies have revealed at least 6 dominant mutations in LRRK2 linked to Parkinson's disease, alongside one associated with cancer. It is now well established that coding changes in LRRK2 are one of the most common causes of Parkinson's. Genome-wide association studies (GWAs) have, more recently, reported single nucleotide polymorphisms (SNPs) around the LRRK2 locus to be associated with risk of developing sporadic Parkinson's disease and inflammatory bowel disorder. The functional research that has followed these genetic breakthroughs has generated an extensive literature regarding LRRK2 pathophysiology; however, there is still no consensus as to the biological function of LRRK2. To provide insight into the aspects of cell biology that are consistently related to LRRK2 activity, we analysed the plethora of candidate LRRK2 interactors available through the BioGRID and IntAct data repositories. We then performed GO terms enrichment for the LRRK2 interactome. We found that, in two different enrichment portals, the LRRK2 interactome was associated with terms referring to transport, cellular organization, vesicles and the cytoskeleton. We also verified that 21 of the LRRK2 interactors are genetically linked to risk for Parkinson's disease or inflammatory bowel disorder. The implications of these findings are discussed, with particular regard to potential novel areas of investigation

    An Interpretation of Argentine Economic and Political History: Dutch Disease on the Pampas

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    An interpretation of Argentine history using the economic condition "the Dutch Disease." As argued here, Argentina's current economic situation is the result of previous governments' poor handling of the Dutch Disease, which was caused by a booming agricultural export sector
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