Towards a Taxonomy of Information Systems: Or Does Anyone Need a Taxi?

Many academic and practical traditions have been brought to bear upon the field of business information systems in an attempt to understand a rapidly changing subject. The insights provided by traditional disciplines to an essentially multi-disciplinary subject is essential and very healthy. However, there is a danger of proliferating many different, overlapping frameworks of information systems. There is a need to review the frameworks and suggest a way of integrating several approaches. The future research effort depends upon a consistent set of data being available and discussed. This paper reviews previous frameworks used to promote the understanding and discussion of information systems. The one-dimensional approach is rejected in favour of a three-dimensional approach built around three basic questions characterized as the three Ts. What tasks does the information system have to perform? What technology can best deliver the systems? In what timeframe are we operating? The paper concludes by suggesting an integrated taxonomy, based on the three Ts as the basis for future research and discussion

The Role of Contextual Clues in the Creation of Information Overload

There has been an explosion of new forms of communications media for interpersonal communication. There is anecdotal evidence of people suffering from 'information overload' as a result of these developments. This paper presents the results from, and analysis of, a case study of a perceived problem of information overload from e-mail in a large international organization: Watson Wyatt Partners. The research took two approaches to exploring the problem. The first was a survey of 1500 members of staff in the UK and Europe. This was aimed at collecting factual information. The second approach was to conduct follow up interviews with 19 people at two sites in the UK to explore some of the issues raised by the survey in greater depth. In the paper, we argue that for CMCs (Computer Mediated Communications) to be effective there is a need to establish a 'context' in which the message can be interpreted. In doing so, we will demonstrate that ignoring the degree of 'context' a media provides can adversely affect the users perceptions of that media.Electronic mail, e-mail, CMC, communication technology, contextual clues, information overload

Local content in local voices

New technology is becoming more accessible to rural communities in the Cajamarca region of Peru in this podcasting experiment. Farmers can now get relevant information in a language they can understand

Protocols used to determine the influence of backpack load on physiological variables. Systematic review

[EN]Professional mountain rescue mountain groups use backpack equipment in their professional activities. The velocity of ambulation, gradient, load and the participant's physical characteristics have been described in the scientific literature as influential factors on response to exercise. The purpose of the present systematic review is to assess the protocols used to investigate the effects of backpacks and their influence on physiological responses at laboratory. A total of 14 articles were included in the review. Most research studies indicated participants were not experienced with backpack carriage. We observed a certain threshold on physiological changes in response to exercise was between 20 and 40 kg of backpack load. In conclusion, there is a heterogeneity of protocols used at the laboratory, hampering the comparison between different results. Future research should focus on the design of protocols that reproduce real scenarios of targeted populations. Relevane to industry: Rescue groups, firefighters and military personnel carry load with backpack in emergency interventions. This review analyzes different types of methodological protocols that investigate the influence of backpack load on physiological responses during exercise. The result will help manufacturer design backpacks considering the physiological burden of backpack carriage.This work was supported by The Basque Government to the author APJ with predoctoral grant [PRE_2019_2_0102]

Peptidoglycan synthesis drives a single population of septal cell wall synthases during division in Bacillus subtilis

Bacterial cell division requires septal peptidoglycan (sPG) synthesis by the divisome complex. Treadmilling of the essential tubulin homologue FtsZ has been implicated in septal constriction, though its precise role remains unclear. Here we used live-cell single-molecule imaging of the divisome transpeptidase PBP2B to investigate sPG synthesis dynamics in Bacillus subtilis. In contrast to previous models, we observed a single population of processively moving PBP2B molecules whose motion is driven by peptidoglycan synthesis and is not associated with FtsZ treadmilling. However, despite the asynchronous motions of PBP2B and FtsZ, a partial dependence of PBP2B processivity on FtsZ treadmilling was observed. Additionally, through single-molecule counting experiments we provide evidence that the divisome synthesis complex is multimeric. Our results support a model for B. subtilis division where a multimeric synthesis complex follows a single track dependent on sPG synthesis whose activity and dynamics are asynchronous with FtsZ treadmilling

Comparative Effectiveness Research: Challenges for Medical Journals

Editors from a number of medical journals lay out principles for journals considering publication of Comparative Effectiveness Research (CER). In order to encourage dissemination of this editorial, this article is freely available in PLoS Medicine and will be also published in Medical Decision Making, Croatian Medical Journal, The Cochrane Library, Trials, The American Journal of Managed Care, and Journal of Clinical Epidemiology

Representations of sport in the revolutionary socialist press in Britain, 1988–2012

This paper considers how sport presents a dualism to those on the far left of the political spectrum. A long-standing, passionate debate has existed on the contradictory role played by sport, polarised between those who reject it as a bourgeois capitalist plague and those who argue for its reclamation and reformation. A case study is offered of a political party that has consistently used revolutionary Marxism as the basis for its activity and how this party, the largest in Britain, addresses sport in its publications. The study draws on empirical data to illustrate this debate by reporting findings from three socialist publications. When sport did feature it was often in relation to high profile sporting events with a critical tone adopted and typically focused on issues of commodification, exploitation and alienation of athletes and supporters. However, readers’ letters, printed in the same publications, revealed how this interpretation was not universally accepted, thus illustrating the contradictory nature of sport for those on the far left

Top health research funders' guidance on selecting journals for funded research [version 2; peer review]

Background: Funded health research is being published in journals that many regard as "predatory", deceptive, and non-credible. We do not currently know whether funders provide guidance on how to select a journal in which to publish funded health research. Methods: We identified the largest 46 philanthropic, public, development assistance, public-private partnership, and multilateral funders of health research by expenditure, globally as well as four public funders from lower-middle income countries, from the list at https://healthresearchfunders.org. One of us identified guidance on disseminating funded research from each funders' website (August/September 2017), then extracted information about selecting journals, which was verified by another assessor. Discrepancies were resolved by discussion. Results were summarized descriptively. This research used publicly available information; we did not seek verification with funding bodies. Results: The majority (44/50) of sampled funders indicated funding health research. 38 (of 44, 86%) had publicly available information about disseminating funded research, typically called "policies" (29, 76%). Of these 38, 36 (95%) mentioned journal publication for dissemination of which 13 (36.11%) offer variable guidance on selecting a journal, all of which relate to the funder's open access mandate. Six funders (17%) outlined publisher requirements or features by which to select a journal. One funder linked to a document providing features of journals to look for (e.g. listed in the Directory of Open Access Journals) and to be wary of (e.g., no journal scope statement, uses direct and unsolicited marketing). Conclusions: Few funders provided guidance on how to select a journal in which to publish funded research. Funders have a duty to ensure that the research they fund is discoverable by others. This research is a benchmark for funder guidance on journal selection prior to the January 2021 implementation of Plan S (a global, funder-led initiative to ensure immediate, open access to funded, published research)

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and public health practice. The number of studies assessing the predictive ability is steadily increasing, but they vary widely in completeness of reporting and apparent quality. Transparent reporting of the strengths and weaknesses of these studies is important to facilitate the accumulation of evidence on genetic risk prediction. A multidisciplinary workshop sponsored by the Human Genome Epidemiology Network developed a checklist of 25 items recommended for strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS), building on the principles established by prior reporting guidelines. These recommendations aim to enhance the transparency, quality and completeness of study reporting, and thereby to improve the synthesis and application of information from multiple studies that might differ in design, conduct or analysis

A pragmatic cluster randomised controlled trial of a Diabetes REcall And Management system: the DREAM trial

BACKGROUND: Following the introduction of a computerised diabetes register in part of the northeast of England, care initially improved but then plateaued. We therefore enhanced the existing diabetes register to address these problems. The aim of the trial was to evaluate the effectiveness and efficiency of an area wide 'extended,' computerised diabetes register incorporating a full structured recall and management system, including individualised patient management prompts to primary care clinicians based on locally-adapted, evidence-based guidelines. METHODS: The study design was a pragmatic, cluster randomised controlled trial, with the general practice as the unit of randomisation. Set in 58 general practices in three Primary Care Trusts in the northeast of England, the study outcomes were the clinical process and outcome variables held on the diabetes register, patient-reported outcomes, and service and patient costs. The effect of the intervention was estimated using generalised linear models with an appropriate error structure. To allow for the clustering of patients within practices, population averaged models were estimated using generalized estimating equations. RESULTS: Patients in intervention practices were more likely to have at least one diabetes appointment recorded (OR 2.00, 95% CI 1.02, 3.91), to have a recording of a foot check (OR 1.87, 95% CI 1.09, 3.21), have a recording of receiving dietary advice (OR 2.77, 95% CI 1.22, 6.29), and have a recording of blood pressure (BP) (OR 2.14, 95% CI 1.06, 4.36). There was no difference in mean HbA1c or BP levels, but the mean cholesterol level in patients from intervention practices was significantly lower (-0.15 mmol/l, 95% CI -0.25, -0.06). There were no differences in patient-reported outcomes or in patient-reported use of drugs, or uptake of health services. The average cost per patient was not significantly different between the intervention and control groups. Costs incurred in administering the system at the register and in general practice were in addition to these. CONCLUSION: This study has shown benefits from an area-wide, computerised diabetes register incorporating a full structured recall and individualised patient management system. However, these benefits were achieved at a cost. In future, these costs may fall as electronic data exchange becomes a reliable reality. Trial registration: International Standard Randomised Controlled Trial Number (ISRCTN) Register, ISRCTN32042030