Co-operative accounting; Part I. Store records and accounts; Part II. Co-operative book keeping

It is evident that to be able to have complete information and analysis of the business condition of your Co-operative, in all its phases at almost a moment\u27s notice, is more advantageous than getting such information at the end of a period. With the employment of the system hereinafter described, it is possible for the manager of the store and the Control Committee to keep their fingers on the business pulse of their society at all times. It is worthy of note that by this system an efficient Control Committee can know as much or more about the business than the manager. By checking the records, certifying to the invoices, recording changes in prices, making up the Weekly Statement for the Board of Directors, taking stock, etc., they become thoroughly acquainted with the business procedure of the Co-operative. As the personnel of the committee changes from time to time, it happens that many members of the society develop this very valuable experience. A society with such a Control Committee is never at a loss when a change of manager occurs. While the explanation of this system is given at length, the actual operation of keeping the records is simple, involving on the average about thirty minutes daily of the manager\u27s time, and about two hours weekly by the Control Committee in checking the records once or twice a week

Organic food and health - status and perspectives

In a recent study it was investigated, through a well-controlled animal feeding experiment, whether conventional and organic food products showed differences in animal physiology of a type and magnitude that could indicate that organic products would affect humans differently. The primary, but still tentative conclusion from this study was that the most significant effects on rats was observed on health aspects that have rarely been assessed in prior studies: Immune status, sleep/activity pattern, accumulation of adipose tissue, liver function, and vitamin E status, while a large numbers of markers of “traditional” nutritional value showed no differences. Although the results of the present study could not directly be applied to organic and conventional production systems the observed differences were all in favour of the organic treatment, and thus pointed in the direction of potential health benefits when eating organically grown rather than conventionally grown food. However, this study like other studies related to the issue suffers from the fact that only one replication per food produce was used in the animal studies. Therefore the size of the effects could not be evaluated with respect to replication variation, which could have been determined by establishment of field trials. In addition, it was not possible to correlate the responses of the animals to the analysed diet composition due to the limited number of replicates, whereby the explanations of the effects were limited. Thus, it is of outmost concern that future investigations on the effect of organic food in relation to human health and well-being should be based on well-defined and controlled food produce system with replications

Vibrational Instability of Metal-Poor Low-Mass Main-Sequence Stars

We find that low-degree low-order g-modes become unstable in metal-poor low-mass stars due to the $\varepsilon$-mechanism of the pp-chain. Since the outer convection zone of these stars is limited only to the very outer layers, the uncertainty in the treatment of convection does not affect the result significantly. The decrease in metallicity leads to decrease in opacity and hence increase in luminosity of a star. This makes the star compact and results in decrease in the density contrast, which is favorable to the $\varepsilon$-mechanism instability. We find also instability for high order g-modes of metal-poor low-mass stars by the convective blocking mechanism. Since the effective temperature and the luminosity of metal-poor stars are significantly higher than those of Pop I stars, the stars showing $\gamma$ Dor-type pulsation are substantially less massive than in the case of Pop I stars. We demonstrate that those modes are unstable for about $1\,M_\odot$ stars in the metal-poor case.Comment: 4 pages, 4 figures, To be published in Astrophysics and Space Science Proceedings series (ASSP). Proceedings of the "20th Stellar Pulsation Conference Series: Impact of new instrumentation and new insights in stellar pulsations", 5-9 September 2011, Granada, Spai

SMEI observations of previously unseen pulsation frequencies in γ Doradus

Aims. As g-mode pulsators, gamma-Doradus-class stars may naïvely be expected to show a large number of modes. Taking advantage of the long photometric time-series generated by the solar mass ejection imager (SMEI) instrument, we have studied the star gamma Doradus to determine whether any other modes than the three already known are present at observable amplitude. Methods. High-precision photometric data from SMEI taken between April 2003 and March 2006 were subjected to periodogram analysis with the PERIOD04 package. Results. We confidently determine three additional frequencies at 1.39, 1.87, and 2.743 d−1. These are above and beyond the known frequencies of 1.320, 1.364, and 1.47 d−1. Conclusions. Two of the new frequencies, at 1.39 and 1.87 d−1, are speculated to be additional modes of oscillation, with the third frequency at 2.743−1 a possible combination frequency

Tidal interactions of close-in extrasolar planets: the OGLE cases

Close-in extrasolar planets experience extreme tidal interactions with their host stars. This may lead to a reduction of the planetary orbit and a spin-up of stellar rotation. Tidal interactions have been computed for a number of extrasolar planets in circular orbits within 0.06 AU, namely for OGLE-TR-56 b. We compare our range of the tidal dissipation value with two dissipation models from Sasselov (2003) and conclude that our choices are equivalent to these models. However, applied to the planet OGLE-TR-56 b, we find in contrast to Sasselov (2003) that this planet will spiral-in toward the host star in a few billion years. We show that the average and maximum value of our range of dissipation are equivalent to the linear and quadratic dissipation models of Sasselov (2003). Due to limitations in the observational techniques, we do not see a possibility to distinguish between the two dissipation models as outlined by Sasselov (2003). OGLE-TR-56 b may therefore not serve as a test case for dissipation models. The probable existence of OGLE-TR-3 b at 0.02 AU and the discovery of OGLE-TR-113 b at 0.023 AU and OGLE-TR-132 b at 0.03 AU may also counter Sasselovs (2003) assumption of a pile-up stopping boundary at 0.04 AU.Comment: 7 pages, 4 figure

Asteroseismology of the Transiting Exoplanet Host HD 17156 with HST FGS

Observations conducted with the Fine Guidance Sensor on Hubble Space Telescope (HST) providing high cadence and precision time-series photometry were obtained over 10 consecutive days in December 2008 on the host star of the transiting exoplanet HD 17156b. During this time 10^12 photons (corrected for detector deadtime) were collected in which a noise level of 163 parts per million per 30 second sum resulted, thus providing excellent sensitivity to detection of the analog of the solar 5-minute p-mode oscillations. For HD 17156 robust detection of p-modes supports determination of the stellar mean density of 0.5301 +/- 0.0044 g/cm^3 from a detailed fit to the observed frequencies of modes of degree l = 0, 1, and 2. This is the first star for which direct determination of the mean stellar density has been possible using both asteroseismology and detailed analysis of a transiting planet light curve. Using the density constraint from asteroseismology, and stellar evolution modeling results in M_star = 1.285 +/- 0.026 solar, R_star = 1.507 +/- 0.012 solar, and a stellar age of 3.2 +/- 0.3 Gyr.Comment: Accepted by ApJ; 16 pages, 18 figure

The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed

The well-known antiparasitic compound licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes in parallel with the inhibition of growth of Plasmodium falciparum cultures, the in vitro antiplasmodial effect apparently being an indirect effect on the host cell. In vitro experiments with synchronous cultures demonstrate that inhibition of invasion is the principal mechanism of growth inhibition. The erythrocyte membrane-modifying effect was also transiently observed in vivo in mice after intravenous administration

Near-Infrared Thermal Emission from the Hot Jupiter TrES-2b: Ground-Based Detection of the Secondary Eclipse

We present near-infrared Ks-band photometry bracketing the secondary eclipse of the hot Jupiter TrES-2b using the Wide-field Infrared Camera on the Canada-France-Hawaii Telescope. We detect its thermal emission with an eclipse depth of 0.062 +/- 0.012% (5-sigma). Our best-fit secondary eclipse is consistent with a circular orbit (a 3-sigma upper limit on the eccentricity, e, and argument or periastron, omega, of |ecos(omega)| < 0.0090), in agreement with mid-infrared detections of the secondary eclipse of this planet. A secondary eclipse of this depth corresponds to a day-side Ks-band brightness temperature of TB = 1636 +/- 88 K. Our thermal emission measurement when combined with the thermal emission measurements using Spitzer/IRAC from O'Donovan and collaborators suggest that this planet exhibits relatively efficient day to night-side redistribution of heat and a near isothermal dayside atmospheric temperature structure, with a spectrum that is well approximated by a blackbody. It is unclear if the atmosphere of TrES-2b requires a temperature inversion; if it does it is likely due to chemical species other than TiO/VO as the atmosphere of TrES-2b is too cool to allow TiO/VO to remain in gaseous form. Our secondary eclipse has the smallest depth of any detected from the ground at around 2 micron to date.Comment: ApJ accepted, 8 pages, 9 figures, in emulateapj format

Cancer risk in persons with new-onset anaemia:a population-based cohort study in Denmark

Abstract Background The time interval from first symptom and sign until a cancer diagnosis significantly affects the prognosis. Therefore, recognising and acting on signs of cancer, such as anaemia, is essential. Evidence is sparse on the overall risk of cancer and the risk of specific cancer types in persons with new-onset anaemia detected in an unselected general practice population. We aimed to assess the risk of cancer in persons with new-onset anaemia detected in general practice, both overall and for selected cancer types. Methods This observational population-based cohort study used individually linked electronic data from laboratory information systems and nationwide healthcare registries in Denmark. We included persons aged 40–90 years without a prior history of cancer and with new-onset anaemia (no anaemia during the previous 15 months) detected in general practice in 2014–2018. We measured the incidence proportion and standardised incidence ratios of a new cancer diagnosis (all cancers except for non-melanoma skin cancers) during 12 months follow-up. Results A total of 48,925 persons (median [interquartile interval] age, 69 [55–78] years; 55.5% men) were included in the study. In total, 7.9% (95% confidence interval (CI): 7.6 to 8.2) of men and 5.2% (CI: 4.9 to 5.5) of women were diagnosed with cancer during 12 months. Across selected anaemia types, the highest cancer incidence proportion was seen in women with ‘anaemia of inflammation’ (15.3%, CI: 13.1 to 17.5) (ferritin > 100 ng/mL and increased C-reactive protein (CRP)) and in men with ‘combined inflammatory iron deficiency anaemia’ (19.3%, CI: 14.5 to 24.1) (ferritin < 100 ng/mL and increased CRP). For these two anaemia types, the cancer incidence across cancer types was 10- to 30-fold higher compared to the general population. Conclusions Persons with new-onset anaemia detected in general practice have a high cancer risk; and markedly high for ‘combined inflammatory iron deficiency anaemia’ and ‘anaemia of inflammation’. Anaemia is a sign of cancer that calls for increased awareness and action. There is a need for research on how to improve the initial pathway for new-onset anaemia in general practice