24,737 research outputs found
Is New Hampshire\u27s climate warming?
This Carsey brief looks at temperature anomalies across New Hampshire and shows that not only is the state warmer than it has been in the past, but it is also warming faster than much of the planet. Sociologist Lawrence Hamilton, research associate professor Cameron Wake, and former NH state climatologist Barry Keim analyzed over 100 years of temperatures across the state to produce this data for the Carsey Institute in August 2010
Thanks, but no thanks: women's avoidance of help-seeking in the context of a dependency-related stereotype
The stereotype that women are dependent on men is a commonly verbalized, potentially damaging aspect of benevolent sexism. We investigated how women may use behavioral disconfirmation of the personal applicability of the stereotype to negotiate such sexism. In an experiment (N = 86), we manipulated female college studentsâ awareness that women may be stereotyped by men as dependent. We then placed participants in a situation where they needed help. Women made aware of the dependency stereotype (compared to controls who were not) were less willing to seek help. They also displayed a stronger negative correlation between help-seeking and post help-seeking affect - such that the more help they sought, the worse they felt. We discuss the relevance of these findings for research concerning womenâs help-seeking and their management of sexist stereotyping in everyday interaction. We also consider the implications of our results for those working in domains such as healthcare, teaching and counseling, where interaction with individuals in need and requiring help is common
Measurement of the Nodal Precession of WASP-33 b via Doppler Tomography
We have analyzed new and archival time series spectra taken six years apart
during transits of the hot Jupiter WASP-33 b, and spectroscopically resolved
the line profile perturbation caused by the Rossiter-McLaughlin effect. The
motion of this line profile perturbation is determined by the path of the
planet across the stellar disk, which we show to have changed between the two
epochs due to nodal precession of the planetary orbit. We measured rates of
change of the impact parameter and the sky-projected spin-orbit misalignment of
yr and
~ yr, respectively,
corresponding to a rate of nodal precession of
~ yr. This is only the
second measurement of nodal precession for a confirmed exoplanet transiting a
single star. Finally, we used the rate of precession to set limits on the
stellar gravitational quadrupole moment of
.Comment: Published in ApJL. 5 pages, 3 figures. Corrected error in the
calculation of J_
Planets and Stellar Activity: Hide and Seek in the CoRoT-7 system
Since the discovery of the transiting super-Earth CoRoT-7b, several
investigations have yielded different results for the number and masses of
planets present in the system, mainly owing to the star's high level of
activity. We re-observed CoRoT-7 in January 2012 with both HARPS and CoRoT, so
that we now have the benefit of simultaneous radial-velocity and photometric
data. This allows us to use the off-transit variations in the star's light
curve to estimate the radial-velocity variations induced by the suppression of
convective blueshift and the flux blocked by starspots. To account for
activity-related effects in the radial-velocities which do not have a
photometric signature, we also include an additional activity term in the
radial-velocity model, which we treat as a Gaussian process with the same
covariance properties (and hence the same frequency structure) as the light
curve. Our model was incorporated into a Monte Carlo Markov Chain in order to
make a precise determination of the orbits of CoRoT-7b and CoRoT-7c. We measure
the masses of planets b and c to be 4.73 +/- 0.95 Mearth and 13.56 +/- 1.08
Mearth, respectively. The density of CoRoT-7b is (6.61 +/- 1.72)(Rp/1.58
Rearth)^(-3) g.cm^(-3), which is compatible with a rocky composition. We search
for evidence of an additional planet d, identified by previous authors with a
period close to 9 days. We are not able to confirm the existence of a planet
with this orbital period, which is close to the second harmonic of the stellar
rotation at around 7.9 days. Using Bayesian model selection we find that a
model with two planets plus activity-induced variations is most favoured.Comment: Accepted 2014 July 2. Received 2014 June 30; in original form 2013
May 30 (17 pages, 9 figures
Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients
<b>Purpose</b>: The expression and activation of the Ras/Raf-1/mitogen-activated protein kinase (MAPK) pathway plays an important role in the development and progression of cancer, and may influence response to treatments such as tamoxifen and chemotherapy. In this study we investigated whether the expression and activation of the key components of this pathway influenced clinical outcome, to test the hypothesis that activation of the MAPK pathway drives resistance to tamoxifen and chemotherapy in women with breast cancer.
<b>Experimental Design</b>: Breast tumors from patients at the Glasgow Royal Infirmary and others treated within the BR9601 trial were analyzed for expression of the three Ras isoforms, total Raf-1, active and inactive forms of Raf-1 [pRaf(ser338) and pRaf(ser259), respectively], MAPK, and phospho-MAPK using an immunohistochemical approach. Analyses were done with respect to disease free-survival and overall survival.
<b>Results</b>: Expression and activation of the Ras pathway was associated with loss of benefit from treatment with tamoxifen but not chemotherapy. Overexpression of pRaf(ser338) was associated with shortened disease-free and overall survival time in univariate analyses. Multivariate analysis suggested pRaf(ser338) was independent of known prognostic markers in predicting outcome following tamoxifen treatment (<i>P</i>=0.03).
<b>Conclusion</b>: This study suggests that activation of the Ras pathway predicts for poor outcome on tamoxifen but not chemotherapy, and identifies pRaf(ser338) as a potential marker of resistance to estrogen receptorâtargeted therapy. In addition, it suggests that expression of pRaf(ser338) could identify patients for whom tamoxifen alone is insufficient adjuvant systemic therapy, but for whom the addition of chemotherapy may be of benefit
A search for starlight reflected from HD 75289 b
We have used a doppler tomographic analysis to conduct a deep search for the
starlight reflected from the planetary companion to HD 75289. In 4 nights on
VLT2/UVES in January 2003, we obtained 684 high resolution echelle spectra with
a total integration time of 26 hours. We establish an upper limit on the
planet's geometric albedo p < 0.12 (to the 99.9% significance level) at the
most probable orbital inclination i ~ 60 degrees, assuming a grey albedo, a
Venus-like phase function and a planetary radius R_p = 1.6 R_Jup. We are able
to rule out some combinations of the predicted planetary radius and atmospheric
albedo models with high, reflective cloud decks.Comment: 5 pages, 5 figures, MNRAS accepted 12 Oct 200
Stoichiometry control of sputtered CuCl thin films: Influence on ultraviolet emission properties
We demonstrate that the chemical composition of the sputtered CuCl thin films could be finely controlled by adjusting the bias to the substrate. The films deposited without any intentional bias were Cl rich (CuCl1+x), a bias of â22 V yielded stoichiometric CuCl, and a further increase in the negative bias resulted in Cl deficient films (CuCl1âx). The crystalline and optical properties were found to be associated with the chemical composition. Cl rich films showed a deep level green emission at around 515 nm in addition to ultraviolet (UV) excitonic emission. The stoichiometric films have higher optical quality, exhibiting a sharp UV emission at around 385 nm at room temperature, compared to nonstoichiometric samples. Visible luminescence related to deep level defects was not observed in the stoichiometric films. Changes in energy of the flux from the target and the subsequent ion bombardment on the substrate surface are correlated with the variations in chemical composition and their impact on the film microstructure and UV emission
Contextual Network Navigation to provide Situational Awareness for Network Administrators
â© 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.One of the goals of network administrators is to identify and block sources of attacks from a network steam. Various tools have been developed to help the administrator identify the IP or subnet to be blocked, however these tend to be non-visual. Having a good perception of the wider network can aid the administrator identify their origin, but while network maps of the Internet can be useful for such endeavors, they are difficult to construct, comprehend and even utilize in an attack, and are often referred to as being âhairballsâ. We present a visualization technique that displays pathways back to the attacker; we include all potential routing paths with a best-efforts identification of the commercial relationships involved. These two techniques can potentially highlight common pathways and/or networks to allow faster, more complete resolution to the incident, as well as fragile or incomplete routing pathways to/from a network. They can help administrators re-profile their choice of IP transit suppliers to better serve a target audience
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