The Importance of Nutrition in Hypertension

Arterial hypertension (AH) is considered to be one of the most relevant cardiovascular risk factors, and its wide prevalence in all age ranges makes it necessary to analyse all the possible causes and treatments. In this special issue, nutritional interventions are examined either as causes or as treatments of AH. [...]

O CAMPO DE MOBILIZAÇÃO DO DIREITO CONTRA OS TRANSGÊNICOS: repertórios, atores e enquadramentos

Nesta dissertação, buscamos compor o campo de mobilização do direito contra os transgênicos (CMDT) através dos atores, arenas e estratégias que influem e se relacionam com o IDEC (Instituto Brasileiro de Defesa do Consumidor) e a AS-PTA (Assessoria e Serviços a Projetos em Agricultura Alternativa). As duas associações mostram como nem toda aliança se dá entre atores com os mesmos objetivos específicos e estratégias iguais. Pelo contrário, denotam como entidades diferentes podem se juntar com estratégias que se complementam a depender do contexto social, político e econômico. Além disso, ambas possuem repertórios e formas de atuação diversificadas, inclusive com movimentos de especialização em temas e estratégias. Adotamos a utilização de múltiplas técnicas de pesquisa pelo fato da discussão política que queremos estabelecer em torno da transgenia atravessar múltiplos campos disciplinares ciências sociais, direito e ambiente natural. Dentre os autores usados, tomamos como partida pesquisadores que se utilizam de uma visão histórica, tendo em vista o processo político, como Tilly (2010) e Tarrow (2009) e algumas abordagens do mobilization of law. Além disso, adotamos a visão relacional, principalmente de Rucht (2004), e interpretativa, especialmente a de McCann (2006, 2010). Por fim, concluímos que temos no caso dos transgênicos uma accountability muito baixa, revelando um sistema político democrático deficiente em tratar sobre questões de técnica e de política. Ainda assim, o judiciário se mostrou um poder aberto a muitas demandas da sociedade civil. Este trabalho vai contra a ideia de generalizar os movimentos sociais como hipossuficientes, e revela a importância da atuação de organizações neste conflito específico

Integrated stratigraphy and astrochronology of the Messinian GSSP at Oued Akrech (Atlantic Morocco)

A much improved high-resolution integrated stratigraphy (calcareous plankton biostratigraphy, magnetostratigraphy, cyclostratigraphy) is presented for the classic section of Oued Akrech (Atlantic Morocco) straddling the Tortonian^Messinian boundary. Magnetobiostratigraphic correlations with time-equivalent and astronomically dated sections in the Mediterranean indicate that cyclic alternations of indurated light beige coloured marls and softer, more clayey and reddish coloured marls are dominantly precession-controlled. Characteristic sedimentary cycle patterns, in particular those reflecting precession^obliquity interference, allow for one possible tuning, thus providing accurate astronomical ages for cycles, calcareous plankton events and magnetic reversals. The tuning further indicates that the reddish layers are the equivalent of sapropels in the Mediterranean. The Messinian Global boundary Stratotype Section and Point (GSSP) has recently been formally defined at the base of the reddish layer of cycle No. 15 in section Oued Akrech. This level coincides closely with the first regular occurrence of the Globorotalia miotumida group and is astronomically dated at 7.251 Ma. The global correlation potential is guaranteed by the straightforward calibration of the Oued Akrech magnetostratigraphy to the geomagnetic polarity time scale, locating the GSSP within C3Br.1r. In the marine realm the calcareous nannofossil genus Amaurolithus provides a series of extremely useful events to delimit the boundary on a global scale. The astronomical tuning guarantees a direct first-order calibration of the Messinian GSSP to the standard geological time scale once, as anticipated, the late Miocene part of the astronomical time scale has been incorporated

Diet of juveniles of the venomous frog Aparasphenodon brunoi (Amphibia: Hylidae) in southeastern Brazil

Seventy juvenile individuals of Aparasphenodon brunoi were collected on the low parts of tree trunks in an Atlantic Forest remnant. Arthropods were the dominant prey found in their stomachs. Coleoptera (adult and larvae) was the most important prey regarding prey frequency, number, weight, and index of relative importance. Secondary preys included Hymenoptera that was important regarding number of prey and Hemiptera that was important regarding prey weight. Trophic ontogeny was detected. The diversity of prey suggests A. brunoi is an opportunistic sit-and-wait predator

Diet of juveniles of the venomous frog Aparasphenodon brunoi (Amphibia: Hylidae) in southeastern Brazil

Seventy juvenile individuals of Aparasphenodon brunoi were collected on the low parts of tree trunks in an Atlantic Forest remnant. Arthropods were the dominant prey found in their stomachs. Coleoptera (adult and larvae) was the most important prey regarding prey frequency, number, weight, and index of relative importance. Secondary preys included Hymenoptera that was important regarding number of prey and Hemiptera that was important regarding prey weight. Trophic ontogeny was detected. The diversity of prey suggests A. brunoi is an opportunistic sit-and-wait predator

P73 Preliminary results of the Study of Acute Liver Transplant (SALT): NSAID exposure and risk of acute liver failure leading to transplantation in 7 European countries

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Waiting times for diagnosis of attention-deficit hyperactivity disorder in children and adolescents referred to Italian ADHD centers must be reduced

BACKGROUND: To investigate timely access to and the time needed to complete the diagnostic path of children and adolescents with suspected attention deficit hyperactivity disorder (ADHD) in the 18 Italian Lombardy Region ADHD reference centers. METHODS: Data of children and adolescents enrolled in the Regional ADHD disease-oriented Registry for suspected ADHD who requested their first visit in 2013-2017 were analyzed. RESULTS: The sample comprised 2262 children and adolescents aged 5-17\u2009years who accessed the ADHD centers for diagnostic classification and management. The median waiting time was of 177\u2009days (range 66-375) from the request for the initial appointment to the completion of the diagnostic path, with a three - fold difference between centers. In addition to the center, the strongest significant predictors of long waiting times were age comorbidities, the severity of the disorder, and having already completed some diagnostic procedures provided by the common standard path. CONCLUSIONS: To guarantee an equal standard of care in ADHD centers for all children and adolescents there is a pressing need to reduce the times to complete the diagnostic path. It is the task of both policymakers and each center to optimize the quality of the service and of the care delivered

Hypotensive effect and endothelium-dependent vascular action of leaves of Alpinia purpurata (Vieill) K. Schum

The aims of this study were to evaluate the chemical profile, vascular reactivity, and acute hypotensive effect (AHE) of the ethanolic extract of leaves of Alpinia purpurata (Vieill) K. Schum (EEAP). Its chemical profile was evaluated using HPLC-UV, ICP-OES, and colorimetric quantification of total flavonoids and polyphenols. The vascular reactivity of the extract was determined using the mesenteric bed isolated from WKY. AHE dose-response curves were obtained for both EEAP and inorganic material isolated from AP (IAP) in WKY and SHR animals. Cytotoxic and mutagenic safety levels were determined by the micronucleus test. Rutin-like flavonoids were quantified in the EEAP (1.8 ± 0.03%), and the total flavonoid and polyphenol ratios were 4.1 ± 1.8% and 5.1 ± 0.3%, respectively. We observed that the vasodilation action of EEAP was partially mediated by nitric oxide (·NO). The IAP showed the presence of calcium (137.76 ± 4.08 μg mg-1). The EEAP and IAP showed an AHE in WKY and SHR animals. EEAP did not have cytotoxic effects or cause chromosomic alterations. The AHE shown by EEAP could result from its endothelium-dependent vascular action. Rutin-like flavonoids, among other polyphenols, could contribute to these biological activities, and the calcium present in EEAP could act in a synergistic way