Can Virialization Shocks be Detected Around Galaxy Clusters Through the Sunyaev-Zel'dovich Effect?

In cosmological structure formation models, massive non-linear objects in the process of formation, such as galaxy clusters, are surrounded by large-scale shocks at or around the expected virial radius. Direct observational evidence for such virial shocks is currently lacking, but we show here that their presence can be inferred from future, high resolution, high-sensitivity observations of the Sunyaev-Zel'dovich (SZ) effect in galaxy clusters. We study the detectability of virial shocks in mock SZ maps, using simple models of cluster structure (gas density and temperature distributions) and noise (background and foreground galaxy clusters projected along the line of sight, as well as the cosmic microwave background anisotropies). We find that at an angular resolution of 2'' and sensitivity of 10 micro K, expected to be reached at ~ 100 GHz frequencies in a ~ 20 hr integration with the forthcoming ALMA instrument, virial shocks associated with massive M ~ 10^15 M_Sun clusters will stand out from the noise, and can be detected at high significance. More generally, our results imply that the projected SZ surface brightness profile in future, high-resolution experiments will provide sensitive constraints on the density profile of cluster gas.Comment: 15 pages, submitted to Ap

Finding the Electromagnetic Counterparts of Cosmological Standard Sirens

The gravitational waves (GW) emitted during the coalescence of supermassive black holes (SMBHs) in the mass range 10^4-10^7 M_sun will be detectable out to high redshifts with LISA. We calculate the size and orientation of the three-dimensional error ellipse in solid angle and redshift within which the LISA event could be localized using the GW signatures alone. We take into account uncertainties in LISA's measurements of the luminosity distance and direction to the source, in the background cosmology, in weak gravitational lensing magnification due to inhomogeneities along the line of sight, and potential source peculiar velocities. We find that weak lensing errors exceed other sources of uncertainties by nearly an order of magnitude. Under the plausible assumption that BH mergers are accompanied by gas accretion leading to Eddington-limited quasar activity, we then compute the number of quasars that would be found in a typical LISA error volume, as a function of BH mass and redshift. We find that low redshifts offer the best opportunities to identify quasar counterparts to cosmological standard sirens, and that the LISA error volume will typically contain a single near-Eddington quasar at z=1. This will allow a straightforward test of the hypothesis that BH mergers are accompanied by bright quasar activity and, if the hypothesis proves correct, will guarantee the identification of a unique quasar counterpart. This would yield unprecedented tests of the physics of SMBH accretion, and offer an alternative method to precisely constrain cosmological parameters [abridged].Comment: 11 pages, 4 figures, version accepted for publication in Ap

Fast Measurements of the Electron Beam Transverse Size and Position on SOLEIL Storage Ring

On SOLEIL storage ring, three beamlines are dedicated to electron beam diagnostics: two in the X-ray range and one in the visible range. The visible range beamline uses the synchrotron radiation which is emitted in one of the ring dipoles and further extracted by a slotted mirror operated in surf-mode (surfing on the upper part of the synchrotron layer). The radiation in the visible range is then transported towards a diagnostic hutch in the experimental hall, allowing electron beam imaging at the source point onto a standard CCD camera. In the perspective of prototyping works for the eventually forthcoming upgrade of SOLEIL, and for the on-going commissioning of a new Multipole Injection Kicker (MIK), we recently installed in this hutch two new branches ended by two new cameras (a KALYPSO system and a standard CMOS camera). We report in this paper the optimization we performed on the mirror mode of operation, as well as on spectral filtering, polarization selection, image plane location, fast acquisition tools, to improve the resolution and increase the speed of our initial transverse beam size measurement at source point

Turbulence driven by outflow-blown cavities in the molecular cloud of NGC 1333

Outflows from young stellar objects have been identified as a possible source of turbulence in molecular clouds. To investigate the relationship between outflows, cloud dynamics and turbulence, we compare the kinematics of the molecular gas associated with NGC 1333, traced in 13CO(1-0), with the distribution of young stellar objects (YSOs) within. We find a velocity dispersion of ~ 1-1.6 km/s in 13CO that does not significantly vary across the cloud, and is uncorrelated with the number of nearby young stellar outflows identified from optical and submillimeter observations. However, from velocity channel maps we identify about 20 cavities or depressions in the 13CO intensity of scales > 0.1-0.2 pc and velocity widths 1-3 km/s. The cavities exhibit limb brightened rims in both individual velocity channel maps and position velocity diagrams, suggesting that they are slowly expanding. We interpret these cavities to be remnants of past YSO outflow activity: If these cavities are presently empty, they would fill in on time scales of a million years. This can exceed the lifetime of a YSO outflow phase, or the transit time of the central star through the cavity, explaining the the absence of any clear correlation between the cavities and YSO outflows. We find that the momentum and energy deposition associated with the expansion of the cavities is sufficient to power the turbulence in the cloud. In this way we conclude that the cavities are an important intermediary step between the conversion of YSO outflow energy and momentum into cloud turbulent motions.Comment: Accepted for publication in ApJ. Check out http://astro.pas.rochester.edu/~aquillen/coolpics.html for channel map and PosVel movies of N133

Hallazgos clínico-patológicos compatibles con intoxicación con ionóforos en búfalas: primer reporte en Argentina

Se describe un presunto caso de intoxicación con ionóforos en búfalas de un tambo de la Provincia de Buenos Aires, Argentina, las cuales habían consumido pasturas y ración comercial formulada para bovinos en ordeñe, conteniendo monensina. Murieron 5 de las 50 búfalas en ordeñe, manifestando taquipnea, disnea, sialorrea, decúbito y muerte. Durante la necropsia se observó hidrotórax, ascitis, hígado con puntillado hemorrágico, edema en vesícula biliar, duodeno y diafragma, así como coloración blanquecina en miocardio. Microscópicamente se evidenciaron miocarditis y miositis necrotizante no supurativa, hepatitis centrolobulillar necrotizante y edema pulmonar severo. La actividad de las enzimas creatinfosfoquinasa y aspartato amino transferasa estaba elevada en animales muestreados al azar. Los datos anamnésicos y clínico-patológicos fueron suficientes para determinar a la intoxicación por ionóforos como el diagnóstico presuntivo de esta mortandad, siendo éste el primer reporte en búfalos de Argentin

Evaluating consumptive and nonconsumptive predator effects on prey density using field time‐series data

Determining the degree to which predation affects prey abundance in natural communities constitutes a key goal of ecological research. Predators can affect prey through both consumptive effects (CEs) and nonconsumptive effects (NCEs), although the contributions of each mechanism to the density of prey populations remain largely hypothetical in most systems. Common statistical methods applied to time‐series data cannot elucidate the mechanisms responsible for hypothesized predator effects on prey density (e.g., differentiate CEs from NCEs), nor can they provide parameters for predictive models. State‐space models (SSMs) applied to time‐series data offer a way to meet these goals. Here, we employ SSMs to assess effects of an invasive predatory zooplankter, Bythotrephes longimanus, on an important prey species, Daphnia mendotae, in Lake Michigan. We fit mechanistic models in an SSM framework to seasonal time series (1994–2012) using a recently developed, maximum‐likelihood–based optimization method, iterated filtering, which can overcome challenges in ecological data (e.g., nonlinearities, measurement error, and irregular sampling intervals). Our results indicate that B. longimanus strongly influences D. mendotae dynamics, with mean annual peak densities of B. longimanus observed in Lake Michigan estimated to cause a 61% reduction in D. mendotae population growth rate and a 59% reduction in peak biomass density. Further, the observed B. longimanus effect is most consistent with an NCE via reduced birth rates. The SSM approach also provided estimates for key biological parameters (e.g., demographic rates) and the contribution of dynamic stochasticity and measurement error. Our study therefore provides evidence derived directly from survey data that the invasive zooplankter B. longimanus is affecting zooplankton demographics and offer parameter estimates needed to inform predictive models that explore the effect of B. longimanus under different scenarios, such as climate change.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/148243/1/ecy2583-sup-0001-AppendixS1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/148243/2/ecy2583_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/148243/3/ecy2583.pd

Probing the last scattering surface through the recent and future CMB observations

We have constrained the extended (delayed and accelerated) models of hydrogen recombination, by investigating associated changes of the position and the width of the last scattering surface. Using the recent CMB and SDSS data, we find that the recent data constraints favor the accelerated recombination model, though the other models (standard, delayed recombination) are not ruled out at 1-$\sigma$ confidence level. If the accelerated recombination had actually occurred in our early Universe, baryonic clustering on small-scales is likely to be the cause of it. By comparing the ionization history of baryonic cloud models with that of the best-fit accelerated recombination model, we find that some portion of our early Universe has baryonic underdensity. We have made the forecast on the PLANCK data constraint, which shows that we will be able to rule out the standard or delayed recombination models, if the recombination in our early Universe had proceeded with $\epsilon_\alpha\sim-0.01$ or lower, and residual foregrounds and systematic effects are negligible.Comment: v2: matched with the accepted version (conclusions unchanged

Association of combined PD- L1 expression and tumour- infiltrating lymphocyte features with survival and treatment outcomes in patients with metastatic melanoma

BackgroundRecent advances obtained with immune checkpoint inhibitors (ICIs) targeting the programmed cell death- 1 (PD- 1) protein have significantly improved the outcome of patients with metastatic melanoma. The PD- L1 expression in tumour cells as detected by immunohistochemistry is a predictive biomarker in some solid tumours, but appears insufficient as prognostic or predictive factor of response to ICIs in metastatic melanomas.ObjectivesWe investigated whether the presence and the features of pretreatment CD8+tumour- infiltrating T lymphocytes (TILs) could be a complementary prognostic or predictive biomarker in patients with metastatic melanoma.MethodsIn this retrospective study, we evaluated the association of PD- L1 expression - ¥5% of tumour cells combined with TIL features (CD8, CD28, Ki67) with the overall survival (OS) among 51 patients treated with ICIs and 54 patients treated with other treatment options (non- ICIs).ResultsPD- L1 positivity was observed in 33% and 39% of primary melanomas and matched metastases, respectively, with, however, poor concordance between the primary and the matched metastatic site (κ = 0.283). No significant association was noted between PD- L1 expression and CD8+TIL profile analysed as single markers and OS or response to immunotherapy. Instead, their combined analysis in primary melanoma samples showed that the PD- L1- /CD8+status was significantly associated with prolonged OS in the whole population (P = 0.04) and in the subgroup treated with non- ICIs (P = 0.009). Conversely, the PD- L1+/CD8+ status was a good prognostic factor in patients treated with ICIs (P = 0.022), whereas was significantly associated with poor prognosis in patients treated with non- ICIs (P = 0.014). While the expression of CD28 was not related to outcome, the Ki67 expression was significantly associated with poor OS in the subgroup CD8+TIL+/PD- L1- (P = 0.02).ConclusionsThe pretreatment combination of PD- L1 expression with the level of CD8+TILs could better assess OS and predict therapeutic response of patients with metastatic melanoma treated by either immunotherapy or other treatment regimens.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/155478/1/jdv16016_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155478/2/jdv16016.pd

HAT-P-50b, HAT-P-51b, HAT-P-52b, and HAT-P-53b: Three Transiting Hot Jupiters and a Transiting Hot Saturn From the HATNet Survey

We report the discovery and characterization of four transiting exoplanets by the HATNet survey. The planet HAT-P-50b has a mass of 1.35 M_J and a radius of 1.29 R_J, and orbits a bright (V = 11.8 mag) M = 1.27 M_sun, R = 1.70 R_sun star every P = 3.1220 days. The planet HAT-P-51b has a mass of 0.31 M_J and a radius of 1.29 R_J, and orbits a V = 13.4 mag, M = 0.98 M_sun, R = 1.04 R_sun star with a period of P = 4.2180 days. The planet HAT-P-52b has a mass of 0.82 M_J and a radius of 1.01 R_J, and orbits a V = 14.1 mag, M = 0.89 M_sun, R = 0.89 R_sun star with a period of P = 2.7536 days. The planet HAT-P-53b has a mass of 1.48 M_J and a radius of 1.32 R_J, and orbits a V = 13.7 mag, M = 1.09 M_sun, R = 1.21 R_sun star with a period of P = 1.9616 days. All four planets are consistent with having circular orbits and have masses and radii measured to better than 10% precision. The low stellar jitter and favorable R_P/R_star ratio for HAT-P-51 make it a promising target for measuring the Rossiter-McLaughlin effect for a Saturn-mass planet.Comment: Submitted to AJ. 20 pages, 9 figures, 5 tables. Data available at http://hatnet.org

The deceleration of Giant Herbig-Haro Flows

It has been recently discovered that spatially separated Herbig-Haro objects, once considered unrelated, are linked within a chain that may extend for parsecs in either direction of the embedded protostar forming a "giant Herbig-Haro jet". Presently, several dozen of these giant flows have been detected and the best documented example, the HH~34 system, shows a systematic velocity decrease with distance on either side of the source. In this paper, we have modeled giant jets by performing fully three-dimensional simulations of overdense, radiatively cooling jets modulated with long-period (P $\sim$ several hundred years) and large amplitude sinusoidal velocity variability at injection ($\Delta v \sim$ mean jet flow velocity). Allowing them to travel over a distance well beyond the source, we have found that multiple travelling pulses develop and their velocity indeed falls off smoothly and systematically with distance. This deceleration is fastest if the jet is pressure-confined, in which case the falloff in velocity is roughly consistent with the observations. The deceleration occurs as momentum is transferred by gas expelled sideways from the traveling pulses. The simulation of a pressure-confined, steady-state jet with similar initial conditions to those of the pulsed jet shows that the flow in this case experiences $acceleration$. This result is thus an additional indication that the primary source of deceleration in the giant flows $cannot$ be attributed to braking of the jet head against the external medium.Comment: 25 pages, 10 figures (see higher resolution figures in: http://www.iagusp.usp.br/~dalpino/giants/apj00.tar.gz); ApJ in pres