142 research outputs found
Coordinate Representation of the Two-Spinon wavefunction and Spinon Interaction
By deriving and studying the coordinate representation for the two-spinon
wavefunction, we show that spinon excitations in the Haldane-Shastry model
interact. The interaction is given by a short-range attraction and causes a
resonant enhancement in the two-spinon wavefunction at short separations
between the spinons. We express the spin susceptibility for a finite lattice in
terms of the resonant enhancement, given by the two-spinon wavefunction at zero
separation. In the thermodynamic limit, the spinon attraction turns into the
square-root divergence in the dynamical spin susceptibility.Comment: 19 pages, 5 .eps figure
Separation of Variables in the Classical Integrable SL(3) Magnetic Chain
There are two fundamental problems studied by the theory of hamiltonian
integrable systems: integration of equations of motion, and construction of
action-angle variables. The third problem, however, should be added to the
list: separation of variables. Though much simpler than two others, it has
important relations to the quantum integrability. Separation of variables is
constructed for the magnetic chain --- an example of integrable model
associated to a nonhyperelliptic algebraic curve.Comment: 13 page
Gemini Observations of Disks and Jets in Young Stellar Objects and in Active Galaxies
We present first results from the Near-infrared Integral Field Spectrograph
(NIFS) located at Gemini North. For the active galaxies Cygnus A and Perseus A
we observe rotationally-supported accretion disks and adduce the existence of
massive central black holes and estimate their masses. In Cygnus A we also see
remarkable high-excitation ionization cones dominated by photoionization from
the central engine. In the T-Tauri stars HV Tau C and DG Tau we see
highly-collimated bipolar outflows in the [Fe II] 1.644 micron line, surrounded
by a slower molecular bipolar outflow seen in the H_2 lines, in accordance with
the model advocated by Pyo et al. (2002).Comment: Invited paper presented at the 5th Stromlo Symposium. 9 pages, 7
figures. Accepted for publication in Astrophysics & Space Scienc
A critical role for astrocytes in hypercapnic vasodilation in brain
Cerebral blood flow (CBF) is controlled by arterial blood pressure, arterial CO2, arterial O2, and brain activity and is largely constant in the awake state. Although small changes in arterial CO2 are particularly potent to change CBF (1 mmHg variation in arterial CO2 changes CBF by 3-4%), the coupling mechanism is incompletely understood. We tested the hypothesis that astrocytic prostaglandin E2 (PgE2) plays a key role for cerebrovascular CO2 reactivity and that preserved synthesis of glutathione is essential for the full development of this response.
We combined two-photon imaging microscopy in brain slices with in vivo work in rats and C57Bl/6J mice to examine the hemodynamic responses to CO2 and somatosensory stimulation before and after inhibition of astrocytic glutathione and PgE2 synthesis. We demonstrate that hypercapnia (increased CO2) evokes an increase in astrocyte [Ca2+]i and stimulates COX-1 activity. The enzyme downstream of COX-1 that synthesizes PgE2 (microsomal prostaglandin E synthase-1) depends critically for its vasodilator activity on the level of glutathione in the brain. We show that when glutathione levels are reduced, astrocyte calcium-evoked release of PgE2 is decreased and vasodilation triggered by astrocyte [Ca2+]i in vitro and by hypercapnia in vivo is inhibited.
Astrocyte synthetic pathways, dependent on glutathione, are involved in cerebrovascular reactivity to CO2. Reductions in glutathione levels in ageing, stroke or schizophrenia could lead to dysfunctional regulation of CBF and subsequent neuronal damage
Mechanisms of Post-Stroke Fatigue: A Follow-Up From the Third Stroke Recovery and Rehabilitation Roundtable
Background
Post-stroke fatigue (PSF) is a significant and highly prevalent symptom, whose mechanisms are poorly understood. The third Stroke Recovery and Rehabilitation Roundtable paper on PSF focussed primarily on defining and measuring PSF while mechanisms were briefly discussed. This companion paper to the main paper is aimed at elaborating possible mechanisms of PSF.
Methods
This paper reviews the available evidence that potentially explains the pathophysiology of PSF and draws parallels from fatigue literature in other conditions. We start by proposing a case for phenotyping PSF based on structural, functional, and behavioral characteristics of PSF. This is followed by discussion of a potentially significant role of early inflammation in the development of fatigue, specifically the impact of low-grade inflammation and its long-term systemic effects resulting in PSF. Of the many neurotransmitter systems in the brain, the dopaminergic systems have the most evidence for a role in PSF, along with a role in sensorimotor processing. Sensorimotor neural network dynamics are compromised as highlighted by evidence from both neurostimulation and neuromodulation studies. The double-edged sword effect of exercise on PSF provides further insight into how PSF might emerge and the importance of carefully titrating interventional paradigms.
Conclusion
The paper concludes by synthesizing the presented evidence into a unifying model of fatigue which distinguishes between factors that pre-dispose, precipitate, and perpetuate PSF. This framework will help guide new research into the biological mechanisms of PSF which is a necessary prerequisite for developing treatments to mitigate the debilitating effects of post-stroke fatigue
A CsI(Tl) Scintillating Crystal Detector for the Studies of Low Energy Neutrino Interactions
Scintillating crystal detector may offer some potential advantages in the
low-energy, low-background experiments. A 500 kg CsI(Tl) detector to be placed
near the core of Nuclear Power Station II in Taiwan is being constructed for
the studies of electron-neutrino scatterings and other keV-MeV range neutrino
interactions. The motivations of this detector approach, the physics to be
addressed, the basic experimental design, and the characteristic performance of
prototype modules are described. The expected background channels and their
experimental handles are discussed.Comment: 34 pages, 11 figures, submitted to Nucl. Instrum. Method
A Binary Lensing Event Toward the LMC: Observations and Dark Matter Implications
The MACHO collaboration has recently analyzed 2.1 years of photometric data
for about 8.5 million stars in the Large Magellanic Cloud (LMC). This analysis
has revealed 8 candidate microlensing events and a total microlensing optical
depth of . This significantly
exceeds the number of events (1.1) and the microlensing optical depth predicted
from known stellar populations: , but it is
consistent with models in which about half of the standard dark halo mass is
composed of Machos of mass \sim 0.5 \msun. One of these 8 events appears to
be a binary lensing event with a caustic crossing that is partially resolved
which allows us to estimate the distance to the lenses. If the source star is
not a short period binary star, then we show that the lens system is very
likely to reside in the LMC. However, if we assume that the optical depth for
LMC-LMC lensing is large enough to account for our entire lensing signal, then
the binary event does not appear to be consistent with lensing of a single LMC
source star by a binary residing in the LMC. Thus, while the binary lens may
indeed reside in the LMC, there is no indication that most of the lenses reside
in the LMC.Comment: 5 pages, 3 postscript figures included; To appear in the Proceedings
of the Dark Matter '96 Conference held in Santa Monica, CA, Feb., 199
The 2dF Galaxy Redshift Survey: the dependence of galaxy clustering on luminosity and spectral type
We investigate the dependence of galaxy clustering on luminosity and spectral type using the 2dF Galaxy Redshift Survey (2dFGRS). Spectral types are assigned using the principal-component analysis of Madgwick et al. We divide the sample into two broad spectral classes: galaxies with strong emission lines ('late types') and more quiescent galaxies ('early types'). We measure the clustering in real space, free from any distortion of the clustering pattern owing to peculiar velocities, for a series of volume-limited samples. The projected correlation functions of both spectral types are well described by a power law for transverse separations in the range 2<(σ/h-1 Mpc)<15, with a marginally steeper slope for early types than late types. Both early and late types have approximately the same dependence of clustering strength on luminosity, with the clustering amplitude increasing by a factor of 2.5 between L* and 4L*. At all luminosities, however, the correlation function amplitude for the early types is 50 per cent higher than that of the late types. These results support the view that luminosity, and not type, is the dominant factor in determining how the clustering strength of the whole galaxy population varies with luminosity
The MACHO Project 2nd Year LMC Microlensing Results and Dark Matter Implications
The MACHO Project is searching for galactic dark matter in the form of
massive compact halo objects (Machos). Millions of stars in the Large
Magellanic Cloud (LMC), Small Magellanic Cloud (SMC), and Galactic bulge are
photometrically monitored in an attempt to detect rare gravitational
microlensing events caused by otherwise invisible Machos. Analysis of two years
of photometry on 8.5 million stars in the LMC reveals 8 candidate microlensing
events, far more than the event expected from lensing by low-mass stars
in known galactic populations. From these eight events we estimate the optical
depth towards the LMC from events with 2 < \that < 200 days to be
\tau_2^{200} \approx 2.9 ^{+1.4}_{-0.9} \ten{-7}. This exceeds the optical
depth of 0.5\ten{-7} expected from known stars and is to be compared with an
optical depth of 4.7\ten{-7} predicted for a ``standard'' halo composed
entirely of Machos. The total mass in this lensing population is \approx
2^{+1.2}_{-0.7} \ten{11} \msun (within 50 kpc from the Galactic center). Event
timescales yield a most probable Macho mass of 0.5^{+0.3}_{-0.2}\msun,
although this value is quite model dependent.Comment: 10 pages, 6 epsf figures and style file included, 451k, also at
http://wwwmacho.mcmaster.ca/Pubs/Pubs.html; To appear in the Proceedings of
"Sources and Detection of Dark Matter in the Universe", Santa Monica, CA,
Feb., 199
A comparison of conventional and 137 Cs-based estimates of soil erosion rates on arable and grassland across lowland England and Wales
Soils deliver a range of ecosystem services and underpin conventional global food production which must increase to feed the projected growth in human population. Although soil erosion by water and subsequent sediment delivery to rivers are natural processes, anthropogenic pressures, including modern farming practices and management, have accelerated soil erosion rates on both arable and grassland. A range of approaches can be used to assess and document soil erosion rates and, in the case of the UK, these mainly comprise the 137Cs-based approach, conventional surveys using volumetric measurements, integration of information on suspended sediment flux, fine sediment source apportionment and landscape sediment retention and traditional bounded hydrological monitoring at edge-of-field using experimental platforms. We compare the erosion rates for arable and grassland in lowland England assessed by these different techniques. Rates assessed by volumetric measurements are similar to those generated by integrating information on suspended sediment flux, sources and landscape retention, but are much less than those estimated by the 137Cs-based approach; of the order of one magnitude less for arable land. The 137Cs approach assumes an initial distribution of 137Cs uniformly spread across the landscape and relates the sampled distribution to erosion, but other (transport) processes are also involved and their representation in the calibration procedures remains problematic. We suggest that the 137Cs technique needs to be validated more rigorously and conversion models re-calibrated. As things stand, rates of erosion based on the distribution of 137Cs may well overstate the severity of the problem in lowland Britain and, therefore, are not a reliable indicator of water erosion rates
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