L’Escola Superior d’Art Dramàtic de les Illes Balears (ESADIB): passat, present i reptes de futur

Aquest treball vol estudiar la situació actual de l’Escola Superior d’Art Dramàtic de les Illes Balears (ESADIB) en el marc dels ensenyaments artístics superiors de la Comunitat Autònoma. Per dur a terme aquest propòsit, analitzarem el passat del centre, el eixos programàtics que desenvolupa en el present com a escola superior de formació i recerca en arts escèniques i presentarem els reptes de futur que l’ESADIB ha d’assolir per integrar-se plenament dins l’Espai Europeu de l’Educació Superior (EEES).Este trabajo pretende estudiar la situación actual de la Escuela Superior de Arte Dramático de las Islas Baleares (ESADIB) en el marco de las enseñanzas artísticas superiores de la Comunidad Autónoma. Para llevar a cabo este propósito, analizaremos el pasado del centro, los ejes programáticos que está desarrollando en el presente como escuela superior de formación e investigación en el campo de las artes escénicas y presentaremos los retos de futuro que la ESADIB tiene que conseguir para integrarse plenamente en el Espacio Europeo de la Educación Superior (EEES)

A possible mechanism of ultrafast amorphization in phase-change memory alloys: an ion slingshot from the crystalline to amorphous position

We propose that the driving force of an ultrafast crystalline-to-amorphous transition in phase-change memory alloys are strained bonds existing in the (metastable) crystalline phase. For the prototypical example of GST, we demonstrate that upon breaking of long Ge-Te bond by photoexcitation Ge ion shot from an octahedral crystalline to a tetrahedral amorphous position by the uncompensated force of strained short bonds. Subsequent lattice relaxation stabilizes the tetrahedral surroundings of the Ge atoms and ensures the long-term stability of the optically induced phase.Comment: 6 pages, 3 figure

Estudio de casos y controles entre anastomosis intra y extracorpórea en pacientes intervenidos de hemicolectomía derecha laparoscópica

Introduction: There is still insufficient scientific evidence on which is the best technique to perform the anastomosis -intracorporeal (IC) or extracorporeal (EC)- in right laparoscopic hemicolectomy. The objective of the present study is to determine whether there are differences to compare in both techniques. Material and methods: A study was performed on a prospective patient series subjected to right laparoscopic hemicolectomy in our Hospital. The preoperative and the postoperative variables associated with complications recorded depending on the type of anastomosis. Results: A total of 60 patients were intervened form June 2004 to June 2010 (35 IC; 25 EC). There were no significant differences between both groups as regards baseline preoperative characteristics or associated comorbidities. The median operation time was 212 minutes (142-305 min), with no significant difference between both techniques. The number of lymph nodes removed was higher in the IC group (21 versus 14; p = 0.03). The beginning of oral tolerance and the first bowel movement were significantly earlier in the IC group. The complications rate was similar for both groups (14% IC; 16% EC; p = 0.89). Three patients in the IC group had anastomosis dehiscence. The mortality rate was 2.8% (one patient in each group). Conclusion: Intracorporeal versus extracorporeal anastomosis in right laparoscopic hemicolectomy can obtain a higher number of resected lymph nodes and an earlier oral tolerance and intestinal transit

Metabolic engineering of astaxanthin biosynthesis in maize endosperm and characterization of a prototype high oil hybrid

Maize was genetically engineered for the biosynthesis of the high value carotenoid astaxanthin in the kernel endosperm. Introduction of a β-carotene hydroxylase and a β-carotene ketolase into a white maize genetic background extended the carotenoid pathway to astaxanthin. Simultaneously, phytoene synthase, the controlling enzyme of carotenogenesis, was over-expressed for enhanced carotenoid production and lycopene ε-cyclase was knocked-down to direct more precursors into the β-branch of the extended ketocarotenoid pathway which ends with astaxanthin. This astaxanthin-accumulating transgenic line was crossed into a high oil- maize genotype in order to increase the storage capacity for lipophilic astaxanthin. The high oil astaxanthin hybrid was compared to its astaxanthin producing parent. We report an in depth metabolomic and proteomic analysis which revealed major up- or down- regulation of genes involved in primary metabolism. Specifically, amino acid biosynthesis and the citric acid cycle which compete with the synthesis or utilization of pyruvate and glyceraldehyde 3-phosphate, the precursors for carotenogenesis, were down-regulated. Nevertheless, principal component analysis demonstrated that this compositional change is within the range of the two wild type parents used to generate the high oil producing astaxanthin hybrid

Routes for breaching and protecting genetic privacy

We are entering the era of ubiquitous genetic information for research, clinical care, and personal curiosity. Sharing these datasets is vital for rapid progress in understanding the genetic basis of human diseases. However, one growing concern is the ability to protect the genetic privacy of the data originators. Here, we technically map threats to genetic privacy and discuss potential mitigation strategies for privacy-preserving dissemination of genetic data.Comment: Draft for comment

Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis?

Modulatory cytokines such as IL-4 and IL-10 looked promising biologicals, but suffered from poor exposure at the inflamed joints when administered via the patient-friendly subcutaneous route. Immunocytokines have now been engineered with tissue targeting potential and are a possible solution to this problem, although challenges still exist. Local inflammatory processes cause destruction of extracellular matrix (ECM) components, leading to neo-eptitopes, and/or elicit the synthesis of new ECM components. This makes ECM elements interesting targets for antibody-mediated recognition and retention, to achieve higher levels of immunocytokines at the site of therapeutic interference. The study presented by Schwager and colleagues shows that targeted delivery of IL-10 is more efficacious in experimental arthritis. Clinical studies are warranted to show whether this strategy works for all rheumatoid arthritis patients or is better for subgroups with a defined ECM phenotype. In principle, the scFv-targeting system is plastic enough to allow for personalized strategies

Enhanced Long-Path Electrical Conduction in ZnO Nanowire Array Devices Grown via Defect-Driven Nucleation

Vertical arrays of nanostructures have been widely used as major components in some of the most ground-breaking modern research-based devices, and ZnO nanowires have received particular attention because of their favorable electronic properties. Using a local multiprobe technique to measure the properties of individual ZnO nanowires in vertical arrays, we show for the first time that for metal-catalyzed ZnO nanowire growth the electrical contribution of individual wires to a device is highly dependent on the fate of the catalyst nanoparticle during growth. To overcome the limitations of metal-catalyzed growth, nanowires grown from a defect-driven nucleation process are shown to provide high-quality device structures with excellent long-path electrical conduction

ANÁLISIS DE LA CREACIÓN ACTORAL DESDE LA PERSPECTIVA SEMIÓTICA. UN ESTADO DE LA CUESTIÓN: ANALYSIS OF ACTING CREATION FROM A SEMIOTIC PERSPECTIVE: A STATE OF THE QUESTION

This article focuses on the study of acting, the process of acting creation, from a semiotic perspective. The aim is to discuss and analyse the contributions that this scientific perspective has developed for the understanding of the artistic work carried out by the actor as a communicative and expressive being. The analysis ranges from the first research carried out by the scholars of the Linguistic Circle of Prague, where the structuralist understanding of the actor's creation is of great interest, to the later theatrical theory that posits acting as a partial text within the performance text created from a body in action made up of verbal and non-verbal expressive signs that the receiver-audience must decode. All of this will lead us to reflect on a possible theory of acting from the semiotic perspective from its communicative and significant level.El presente artículo se centra en el estudio de la actuación, del proceso de creación actoral, desde la perspectiva semiótica. Se pretende discutir y analizar las aportaciones que ha desarrollado esta perspectiva científica para la compresión del trabajo artístico que lleva a cabo el actor como ser comunicativo y expresivo. El análisis abarca desde las primeras investigaciones llevadas a cabo por los estudiosos del Círculo Lingüístico de Praga, donde la comprensión estructuralista de la creación actoral es de gran interés, hasta la teoría teatral posterior que plantea la actuación como un texto parcial dentro del texto espectacular creado a partir de un cuerpo en acción conformado por signos expresivos verbales y no verbales que el receptor-público debe descodificar. Palabras clave: Actuación. Semiótica. Texto espectacular. Artes escénicas. Creatividad. Abstract: This article focuses on the study of acting, the process of acting creation, from a semiotic perspective. The aim is to discuss and analyse the contributions that this scientific perspective has developed for the understanding of the artistic work carried out by the actor as a communicative and expressive being. The analysis ranges from the first research carried out by the scholars of the Linguistic Circle of Prague, where the structuralist understanding of the actor’s creation is of great interest, to the later theatrical theory that posits acting as a partial text within the performance text created from a body in action made up of verbal and non-verbal expressive signs that the receiver-audience must decode.   Keywords: Acting. Semiotic. Performance text. Performing arts. Creativity

El actor como imitador/simulador: performance y neurociencia cognitiva.

Este artículo pretende mostrar como los avances actuales en el campo de la cognición motora afectan de manera significativa a las artes escénicas en general y a la comprensión del proceso creativo del actor en particular. El estudio se centra en el estudio del trabajo actoral como imitador y simulador de las acciones físicas que representa en escena. Las aportaciones neurocientíficas dan una nueva orientación al entrenamiento y la técnica actoral, abriendo nuevos horizontes para el estudio de su creatividad a partir de la acción de su cuerpo-mente en un espacio y un tiempo determinados