657 research outputs found
How to optimize nonlinear force-free coronal magnetic field extrapolations from SDO/HMI vector magnetograms?
The SDO/HMI instruments provide photospheric vector magnetograms with a high
spatial and temporal resolution. Our intention is to model the coronal magnetic
field above active regions with the help of a nonlinear force-free
extrapolation code. Our code is based on an optimization principle and has been
tested extensively with semi-analytic and numeric equilibria and been applied
before to vector magnetograms from Hinode and ground based observations.
Recently we implemented a new version which takes measurement errors in
photospheric vector magnetograms into account. Photospheric field measurements
are often due to measurement errors and finite nonmagnetic forces inconsistent
as a boundary for a force-free field in the corona. In order to deal with these
uncertainties, we developed two improvements: 1.) Preprocessing of the surface
measurements in order to make them compatible with a force-free field 2.) The
new code keeps a balance between the force-free constraint and deviation from
the photospheric field measurements. Both methods contain free parameters,
which have to be optimized for use with data from SDO/HMI. Within this work we
describe the corresponding analysis method and evaluate the force-free
equilibria by means of how well force-freeness and solenoidal conditions are
fulfilled, the angle between magnetic field and electric current and by
comparing projections of magnetic field lines with coronal images from SDO/AIA.
We also compute the available free magnetic energy and discuss the potential
influence of control parameters.Comment: 17 Pages, 6 Figures, Sol. Phys., accepte
Regulation of BALB/c 3T3 fibroblast proliferation by B-myb is accompanied by selective activation of cdc2 and cyclin D1 expression.
AMI observations of Lynds Dark Nebulae: further evidence for anomalous cm-wave emission
Observations at 14.2 to 17.9 GHz made with the AMI Small Array towards
fourteen Lynds Dark Nebulae with a resolution of 2' are reported. These sources
are selected from the SCUBA observations of Visser et al. (2001) as small
angular diameter clouds well matched to the synthesized beam of the AMI Small
Array. Comparison of the AMI observations with radio observations at lower
frequencies with matched uv-plane coverage is made, in order to search for any
anomalous excess emission which can be attributed to spinning dust. Possible
emission from spinning dust is identified as a source within a 2' radius of the
Scuba position of the Lynds dark nebula, exhibiting an excess with respect to
lower frequency radio emission. We find five sources which show a possible
spinning dust component in their spectra. These sources have rising spectral
indices in the frequency range 14.2--17.9 GHz. Of these five one has already
been reported, L1111, we report one new definite detection, L675, and three new
probable detections (L944, L1103 and L1246). The relative certainty of these
detections is assessed on the basis of three criteria: the extent of the
emission, the coincidence of the emission with the Scuba position and the
likelihood of alternative explanations for the excess. Extended microwave
emission makes the likelihood of the anomalous emission arising as a
consequence of a radio counterpart to a protostar or a proto-planetary disk
unlikely. We use a 2' radius in order to be consistent with the IRAS
identifications of dark nebulae (Parker 1988), and our third criterion is used
in the case of L1103 where a high flux density at 850 microns relative to the
FIR data suggests a more complicated emission spectrum.Comment: submitted MNRA
First AGILE Catalog of High Confidence Gamma-Ray Sources
We present the first catalog of high-confidence gamma-ray sources detected by
the AGILE satellite during observations performed from July 9, 2007 to June 30,
2008. Catalogued sources are detected by merging all the available data over
the entire time period. AGILE, launched in April 2007, is an ASI mission
devoted to gamma-ray observations in the 30 MeV - 50 GeV energy range, with
simultaneous X-ray imaging capability in the 18-60 keV band. This catalog is
based on Gamma-Ray Imaging Detector (GRID) data for energies greater than 100
MeV. For the first AGILE catalog we adopted a conservative analysis, with a
high-quality event filter optimized to select gamma-ray events within the
central zone of the instrument Field of View (radius of 40 degrees). This is a
significance-limited (4 sigma) catalog, and it is not a complete flux-limited
sample due to the non-uniform first year AGILE sky coverage. The catalog
includes 47 sources, 21 of which are associated with confirmed or candidate
pulsars, 13 with Blazars (7 FSRQ, 4 BL Lacs, 2 unknown type), 2 with HMXRBs, 2
with SNRs, 1 with a colliding-wind binary system, 8 with unidentified sources.Comment: Revised version, 15 pages, 3 figures, 3 tables. To be published in
Astronomy and Astrophysics. Text improved and clarified. Refined analysis of
complex regions of the Galactic plane yields a new list of high-confidence
sources including 47 sources (compared with the 40 sources appearing in the
first version
A Large Scale, Low Frequency Murchison Widefield Array Survey of Galactic HII regions between 260\340
Publications of the Astronomical Society of Australia (PASA), Vol. 33, e020, 17 pages (2016). © Astronomical Society of Australia 2016; published by Cambridge University Press. The online version of this article is published within an Open Access environment subject to the conditions of the Creative Commons Attribution-NonCommercial-ShareAlike license http://creativecommons.org/licenses/ by-nc-sa/3.0/. The written permission of Cambridge University Press must be obtained for commercial re-use. doi:10.1017/pasa.2016.19We have compiled a catalogue of HII regions detected with the Murchison Widefield Array (MWA) between 72 and 231MHz. The multiple frequency bands provided by the MWA allow us identify the characteristic spectrum generated by the thermal Bremsstrahlung process in HII regions. We detect 302 HII regions between 260Peer reviewe
Direct Transactivation of the Anti-apoptotic Gene Apolipoprotein J (Clusterin) by B-MYB
B-MYB is a ubiquitously expressed transcription factor involved in the regulation of cell survival, proliferation, and differentiation. In an attempt to isolate B-MYB-regulated genes that may explain the role of B-MYB in cellular processes, representational difference analysis was performed in neuroblastoma cell lines with different levels of B-MYB expression. One of the genes, the mRNA levels of which were enhanced in B-MYB expressing cells, was ApoJ/Clusterin(SGP-2/TRMP-2) (ApoJ/Clusterin), previously implicated in regulation of apoptosis and tumor progression. Here we show that the human ApoJ/Clusterin gene contains a Myb binding site in its 5\' flanking region, which interacts with bacterially synthesized B-MYB protein and mediates B-MYB-dependent transactivation of the ApoJ/Clusterin promoter in transient transfection assays. Endogenous ApoJ/Clusterin expression is induced in mammalian cell lines following transient transfection of a B-MYB cDNA. Blockage of secreted clusterin by a monoclonal antibody results in increased apoptosis of neuroblastoma cells exposed to the chemotherapeutic drug doxorubicin. Thus, activation of ApoJ/Clusterin by B-MYB may be an important step in the regulation of apoptosis in normal and diseased cell
De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells.
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