931 research outputs found
The SiRi Particle-Telescope System
A silicon particle-telescope system for light-ion nuclear reactions is
described. In particular, the system is designed to be optimized for level
density and gamma-ray strength function measurements with the so-called Oslo
method. Eight trapezoidal modules are mounted at 5 cm distance from the target,
covering 8 forward angles between theta = 40 and 54 degrees. The thin front dE
detectors (130 micrometer) are segmented into eight pads, determining the
reaction angle for the outgoing charged ejectile. Guard rings on the thick back
E detectors (1550 micrometer) guarantee low leakage current at high depletion
voltage.Comment: 6 pages, 8 figure
Transport in ZnCoO thin films with stable bound magnetic polarons
Diluted magnetic ZnCoO films with 5 at.% Co have been fabricated by pulsed laser deposition on c-plane sapphire substrates and Schottky and Ohmic contacts have been prepared in top-top configuration. The diode current is significantly reduced after the diode has been subjected to an external magnetic field. In the reverse bias range the corresponding positive magnetoresistance is persistent and amounts to more than 1800% (50 K), 240% (30 K), and 50% (5 K). This huge magnetoresistance can be attributed to the large internal magnetic field in depleted ZnCoO with ferromagnetic exchange between stable bound magnetic polarons
Observation of large scissors resonance strength in actinides
The orbital M1-scissors resonance (SR) has been measured for the first time
in the quasi-continuum of actinides. Particle-gamma coincidences are recorded
with deuteron and 3He induced reactions on 232Th. The residual nuclei
231,232,233Th and 232,233Pa show an unexpectedly strong integrated strength of
in the Egamma=1.0 - 3.5 MeV region. The increased
gamma-decay probability in actinides due to the SR is important for
cross-section calculations for future fuel cycles of fast nuclear reactors and
may also have impact on stellar nucleosynthesis.Comment: 5 pages and 4 figure
Extraction of thermal and electromagnetic properties in 45Ti
The level density and gamma-ray strength function of 45Ti have been
determined by use of the Oslo method. The particle-gamma coincidences from the
46Ti(p,d gamma)45Ti pick-up reaction with 32 MeV protons are utilized to obtain
gamma-ray spectra as function of excitation energy. The extracted level density
and strength function are compared with models, which are found to describe
these quantities satisfactorily. The data do not reveal any single-particle
energy gaps of the underlying doubly magic 40Ca core, probably due to the
strong quadruple deformation
Cryo-EM structures reveal intricate Fe-S cluster arrangement and charging in Rhodobacter capsulatus formate dehydrogenase
Metal-containing formate dehydrogenases (FDH) catalyse the reversible oxidation of formate to carbon dioxide at their molybdenum or tungsten active site. They display a diverse subunit and cofactor composition, but structural information on these enzymes is limited. Here we report the cryo-electron microscopic structures of the soluble Rhodobacter capsulatus FDH (RcFDH) as isolated and in the presence of reduced nicotinamide adenine dinucleotide (NADH). RcFDH assembles into a 360âkDa dimer of heterotetramers revealing a putative interconnection of electron pathway chains. In the presence of NADH, the RcFDH structure shows charging of cofactors, indicative of an increased electron load
Maximum principle and mutation thresholds for four-letter sequence evolution
A four-state mutation-selection model for the evolution of populations of
DNA-sequences is investigated with particular interest in the phenomenon of
error thresholds. The mutation model considered is the Kimura 3ST mutation
scheme, fitness functions, which determine the selection process, come from the
permutation-invariant class. Error thresholds can be found for various fitness
functions, the phase diagrams are more interesting than for equivalent
two-state models. Results for (small) finite sequence lengths are compared with
those for infinite sequence length, obtained via a maximum principle that is
equivalent to the principle of minimal free energy in physics.Comment: 25 pages, 16 figure
Survival-extinction phase transition in a bit-string population with mutation
A bit-string model for the evolution of a population of haploid organisms,
subject to competition, reproduction with mutation and selection is studied,
using mean field theory and Monte Carlo simulations. We show that, depending on
environmental flexibility and genetic variability, the model exhibits a phase
transtion between extinction and survival. The mean-field theory describes the
infinite-size limit, while simulations are used to study quasi-stationary
properties.Comment: 11 pages, 5 figure
Stochastic slowdown in evolutionary processes
We examine birth--death processes with state dependent transition
probabilities and at least one absorbing boundary. In evolution, this describes
selection acting on two different types in a finite population where
reproductive events occur successively. If the two types have equal fitness the
system performs a random walk. If one type has a fitness advantage it is
favored by selection, which introduces a bias (asymmetry) in the transition
probabilities. How long does it take until advantageous mutants have invaded
and taken over? Surprisingly, we find that the average time of such a process
can increase, even if the mutant type always has a fitness advantage. We
discuss this finding for the Moran process and develop a simplified model which
allows a more intuitive understanding. We show that this effect can occur for
weak but non--vanishing bias (selection) in the state dependent transition
rates and infer the scaling with system size. We also address the Wright-Fisher
model commonly used in population genetics, which shows that this stochastic
slowdown is not restricted to birth-death processes.Comment: 8 pages, 3 figures, accepted for publicatio
Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon
The elongation of eukaryotic selenoproteins relies on a poorly understood process of interpreting in-frame UGA stop codons as selenocysteine (Sec). We used cryo-electron microscopy to visualize Sec UGA recoding in mammals. A complex between the noncoding Sec-insertion sequence (SECIS), SECIS-binding protein 2 (SBP2), and 40S ribosomal subunit enables Sec-specific elongation factor eEFSec to deliver Sec. eEFSec and SBP2 do not interact directly but rather deploy their carboxyl-terminal domains to engage with the opposite ends of the SECIS. By using its Lys-rich and carboxyl-terminal segments, the ribosomal protein eS31 simultaneously interacts with Sec-specific transfer RNA (tRNASec) and SBP2, which further stabilizes the assembly. eEFSec is indiscriminate toward l-serine and facilitates its misincorporation at Sec UGA codons. Our results support a fundamentally distinct mechanism of Sec UGA recoding in eukaryotes from that in bacteria
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