173 research outputs found

    Complete Atrioventricular Heart Block From an Epilepsy Treatment

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    Atrioventricular (AV) heart block without adequate escape rhythm can result in sudden cardiac arrest and death. We report complete (third degree) AV block in a 16 year-old boy as a late effect of vagus nerve stimulation (VNS). He experienced brief, daily, complex partial seizures, treated with lamotrigine, levetiracetam, and the placement of Model 102 VNS at age 4. Electroencephalography (EEG) showed generalized slow spike-and-wave discharges consistent with Lennox-Gastaut syndrome. At age 12, his VNS was changed to Model 303 PereniaDURA/Model 103 Demipulse generator, set at an output current of 2.25 mA on a standard 30 seconds on, 5 minutes off paradigm. At age 16, he experienced episodes of sudden collapse followed by unconsciousness. Holter monitor showed 15 second symptomatic complete AV block without escape (Figure 1). The patient was taking psychotropic medication with potential cardiac side effects: methylphenidate (tachycardia), guanfacine (first degree AV block), and haloperidol (prolonged QT interval, Torsades de Pointes). Haloperidol, methylphenidate, and VNS were stopped without further symptoms. Off these medications, the VNS was resumed at reduced current (1.25 mA), with re-occurrence of symptomatic AV block. Again, the VNS was stopped and symptoms/heart block ceased. Psychotropic medication was resumed without any side effects

    Creating a National Coalition to Address Tractor Overturn Fatalities.

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    Tractor overturns continue to be the leading cause of death on U.S. farms. While rollover protective structures (ROPS) are effective in preventing these fatalities, they are underutilized due to a number of barriers. Past programs in the U.S. and abroad have targeted this area of agricultural safety; however, a national program is not yet in place for U.S. farmers. This study seeks to build a national partnership to address tractor overturn fatalities by increasing the number of tractors with ROPS. A diverse, multisector steering committee has been organized and is working together using Whole System in a Room methods. This method brings together partners from nine stakeholder groups to identify and commit to a collaborative solution to the issue

    Simple, Dark, and Deep: Photographic Theorizations of As-Yet Schools

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    Within the space of this collective image/text article, 18 photographic imagemakers and 4 respondents consider deeply and dialogically a quote from William Ayers’ 2016 book Teaching with Conscience in an Imperfect World: An Invitation. The resulting constellation of images and words (1) realizes a space within which works of art, specifically photographs, operate as centers of meaning to generate educational implications, and (2) theorizes a pedagogy that resists unilateral prescriptions and is instead anchored around openness, expansion, and individualization. The paper begins with a few short pieces from Sarah Pfohl, including an overview of Ayers’ book and ideas from writings on progressive education, object-based teaching and learning, and close/slow looking to position works of art as sites of rich meaning. While contemporary schooling often drives toward monolithic, numerical representations of the learners in its care, the article employs postdigital gestures to argue that learners have more in common with works of art than numbers, and thus, attention to artworks can open valuable implications for teaching and learning. The diverse group of images that follow offer an emerging portrait of teaching practice as a set of constantly shifting constellations moving across deep time and space from the intensely specific to the wide. Four texts think more about schools, education, and art. Finally, there is a postscript from Bill Ayers himself

    Dana Cole, Georgia Division of Public Health, Notifiable Disease Section, Department of Human Resources, 2 Peachtree Free-living Canada Geese and Antimicrobial Resistance

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    We describe antimicrobial resistance among Escherichia coli isolated from free-living Canada Geese in Georgia and North Carolina (USA). Resistance patterns are compared to those reported by the National Antimicrobial Resistance Monitoring System. Canada Geese may be vectors of antimicrobial resistance and resistance genes in agricultural environments

    Free-living Canada Geese and Antimicrobial Resistance

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    We describe antimicrobial resistance among Escherichia coli isolated from free-living Canada Geese in Georgia and North Carolina (USA). Resistance patterns are compared to those reported by the National Antimicrobial Resistance Monitoring System. Canada Geese may be vectors of antimicrobial resistance and resistance genes in agricultural environments

    Bodyweight Perceptions among Texas Women: The Effects of Religion, Race/Ethnicity, and Citizenship Status

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    Despite previous work exploring linkages between religious participation and health, little research has looked at the role of religion in affecting bodyweight perceptions. Using the theoretical model developed by Levin et al. (Sociol Q 36(1):157–173, 1995) on the multidimensionality of religious participation, we develop several hypotheses and test them by using data from the 2004 Survey of Texas Adults. We estimate multinomial logistic regression models to determine the relative risk of women perceiving themselves as overweight. Results indicate that religious attendance lowers risk of women perceiving themselves as very overweight. Citizenship status was an important factor for Latinas, with noncitizens being less likely to see themselves as overweight. We also test interaction effects between religion and race. Religious attendance and prayer have a moderating effect among Latina non-citizens so that among these women, attendance and prayer intensify perceptions of feeling less overweight when compared to their white counterparts. Among African American women, the effect of increased church attendance leads to perceptions of being overweight. Prayer is also a correlate of overweight perceptions but only among African American women. We close with a discussion that highlights key implications from our findings, note study limitations, and several promising avenues for future research

    Controls on Open‐Ocean North Atlantic ΔpCO2 at Seasonal and Interannual Time Scales Are Different

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    The North Atlantic is a substantial sink for anthropogenic CO2. Understanding the mechanisms driving the sink's variability is key to assessing its current state and predicting its potential response to global climate change. Here we apply a time series decomposition technique to satellite and in situ data to examine separately the factors (both biological and nonbiological) that affect the sea‐air CO2 difference (ΔpCO2) on seasonal and interannual time scales. We demonstrate that on seasonal time scales, the subpolar North Atlantic ΔpCO2 signal is predominantly correlated with biological processes, whereas seawater temperature dominates in the subtropics. However, the same factors do not necessarily control ΔpCO2 on interannual time scales. Our results imply that the mechanisms driving seasonal variability in ΔpCO2 cannot necessarily be extrapolated to predict how ΔpCO2, and thus the North Atlantic CO2 sink, may respond to increases in anthropogenic CO2 over longer time scales

    Genome-wide association study identifies loci on 12q24 and 13q32 associated with Tetralogy of Fallot

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    We conducted a genome-wide association study to search for risk alleles associated with Tetralogy of Fallot (TOF), using a northern European discovery set of 835 cases and 5159 controls. A region on chromosome 12q24 was associated (P = 1.4 × 10−7) and replicated convincingly (P = 3.9 × 10−5) in 798 cases and 2931 controls [per allele odds ratio (OR) = 1.27 in replication cohort, P = 7.7 × 10−11 in combined populations]. Single nucleotide polymorphisms in the glypican 5 gene on chromosome 13q32 were also associated (P = 1.7 × 10−7) and replicated convincingly (P = 1.2 × 10−5) in 789 cases and 2927 controls (per allele OR = 1.31 in replication cohort, P = 3.03 × 10−11 in combined populations). Four additional regions on chromosomes 10, 15 and 16 showed suggestive association accompanied by nominal replication. This study, the first genome-wide association study of a congenital heart malformation phenotype, provides evidence that common genetic variation influences the risk of TO
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