Transitions of cardio-metabolic risk factors in the Americas between 1980 and 2014

Describing the prevalence and trends of cardiometabolic risk factors that are associated with non-communicable diseases (NCDs) is crucial for monitoring progress, planning prevention, and providing evidence to support policy efforts. We aimed to analyse the transition in body-mass index (BMI), obesity, blood pressure, raised blood pressure, and diabetes in the Americas, between 1980 and 2014

Deficiências minerais em plantas de bertalha ( Basella alba, L.)

Basella alba is used as a major food on the Amazon region, north Brazil for its high mineral and vitamins content. The purpose of the present work was: a) obtain a clear picture of the macronutrient deficiency; b) growth of the plants in function of (1); c) analyptical levels found in the leaves. Young Basella alba plants (bertalha in Portuguese) were cultivated in pots containing fine pure quartz and irrigated by percolation with different nutrient solutions lacking one of the element at the time. Clear cut symptoms were obtained for all macronutrients. Only the omission of nitrogen and potassium affect the dry matter production of plants. The range in dry matter for unhealthy and healthy leaves were: N% = 1.25--3-55; P% = 0.17-0.36; K% = 0.46-3.55; Ca% = 0,62-1.78; Mg% = 0.37-0.80; S% = 0.19-0.13.Plantas de bertalha (Basella alba, L.) INPA-1 foram cultivadas em casa de vegetação em quartzo moído, irrigadas com soluções nutritivas conforme SARRUGE (1975) e submetidas aos seguintes tratamentos: completo, omissão de N, omissão de P, omissão de K, omissão de Ca, omissão de Mg e omissão de S, com o objetivo de: (a) obter sintomas de deficiência dos ma cronutrientes; (b) analisar o crescimento das plantas através da produção de matéria seca; (c) determinar a concentração dos macronutrientes nas folhas e caules das plantas cultivadas nos diversos tratamentos. Os sintomas visuais de deficiência foram identificados e descritos. As plantas foram coletadas e separadas em raiz, caule, folhas e determinaram-se os teores dos macronutrientes minerais neste material. Os resultados obtidos mostram: - os sintomas visuais de deficiência são bem definidos e de fácil caracterização para todos os nutrientes; - só foi possível detectar efeito na produção de matéria seca das folhas e caules para omissão de nitrogênio e para omissão de potássio nos caules; - os níveis de deficiência e adequação obtidos nas folhas foram respectivamente: N% = 1,25 e 2,63; P% = 0,17 e 0,36; K% = 0,46 e 3,55; Ca% = 0,62e 1,78; Mg% = 0,37 e 0,80; s%= 0,19 e 0,23. - os níveis de deficiência e adequação obtidos nos caules foram respectivamente: N% = 0,67 e 0,98; P% = 0,13 e 0,31; K% = 0,73 e 2,67; Ca% = 0,11 e 0,64; Mg% = 0,08 e 0,20; S% = 0,15 e 0,20

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.</p

A century of trends in adult human height

Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5-22.7) and 16.5 cm (13.3-19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8-144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol�which is a marker of cardiovascular risk�changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95 credible interval 3.7 million�4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world. © 2020, The Author(s), under exclusive licence to Springer Nature Limited

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3�6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55 of the global rise in mean BMI from 1985 to 2017�and more than 80 in some low- and middle-income regions�was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing�and in some countries reversal�of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories. © 2019, The Author(s)

Quality assessment of speckle patterns for digital image correlation

Digital image correlation (DIC) is an optical–numerical full-field displacement measuring technique, which is nowadays widely used in the domain of experimental mechanics. The technique is based on a comparison between pictures taken during loading of an object. For an optimal use of the method, the object of interest has to be covered with painted speckles. In the present paper, a comparison is made between three different speckle patterns originated by the same reference speckle pattern. A method is presented for the determination of the speckle size distribution of the speckle patterns, using image morphology. The images of the speckle patterns are numerically deformed based on a finite element simulation. Subsequently, the displacements are measured with DIC-software and compared to the imposed ones. It is shown that the size of the speckles combined with the size of the used pixel subset clearly influences the accuracy of the measured displacements

ANATOMICAL STUDIES OF IN VITRO ORGANOGENESIS INDUCED IN LEAF-DERIVED EXPLANTS OF PASSIONFRUIT ESTUDOS ANATÔMICOS DA ORGANOGÊNESE IN VITRO INDUZIDA EM EXPLANTES DE FOLHA DE MARACUJÁ

With the aim of studying the organogenesis in vitro in Passiflora edulis Sims f. flavicarpa Deg., the passionfruit, leaf-derived explants were cultured on media containing NAA or BAP and incubated either in continuous darkness or in light. The histological events leading to de novo organ formation were evaluated. Darkness induces rhizogenesis in the presence of NAA, whereas direct shoot regeneration is stimulated by light and BAP. This latter condition is recommended for passionfruit micropropagation as several adventitious shoot buds were formed from meristemoids of parenchymal origin.<br>Com o objetivo de estudar a organogênese in vitro em Passiflora edulis Sims f. flavicarpa Deg., o maracujá-amarelo, explantes derivados de folha foram cultivados em meio contendo NAA ou BAP, no escuro e na presença de luz. Foram descritos os eventos histológicos que levam à formação de novo de órgãos. Concluiu-se que o escuro induz a rizogênese, na presença de NAA, enquanto a regeneração de brotos é estimulada pela luz e BAP. Esta condição é recomendada para micropropagar o maracujá uma vez que vários brotos adventícios são formados a partir de meristemóides de origem parenquimática