Age Dynamics of Changes in Thyroid Volume

Age dynamics of increase in thyroid volume (TV) was studied in healthy persons of both sex. TV was determined based on ultrasound measurements of three linear parameters : length (a), width (b) and thickness (c). TV was calculated with the formula : TV = 2×(0.524×a×b×c). There were 5291 males and 6153 females, whose ages ranged from 3-31 years. Following parameters were studied : absolute increase of TV, growth rate and increase rate of TV, relative growth rate of TV. TV growth was found to be irregular in different age periods. Differences in TV growth between men ane women as well as age periods of the most marked TV growth were ascertained. The obtained results allow to evaluate changes in TV in healthy persons most objectively

SiPM MEPhI Megagrant Developments in Nuclear Medicine

AbstractThree projects has been started in our laboratory as part of megagrant “High energy physics and nuclear medicine with silicon photomultiplier detectors” in NRNU MEPHI. The goal of these projects is development of devices for nuclear medicine in which replacement of photomultiplier tubes (PMT) with solid-state silicon photomultipliers promises various advantages. The first project is full-body SPECT, where replacement of PMT's could reduce size of the detector module and improve spatial resolution while keeping other parameters. The second project is development of a TOF-PET module. Replacement of PMTs with silicon photomultipliers makes it possible to use that detector not only in high magnetic fields but also for Time-of-Flight measurements (higher signal-to-noise ratio on final image) due to very high timing resolution of a SiPM. And the last project is the SiPM-based position-sensitive Gamma-spectrometer for dose monitoring in neutron-capture therapy based on SiPM's

Who wrote one of the first Belarusian plays «Mikhalka»?

В статье рассмотрена история создания одной из первых белорусских пьес «Міхалка». Выявлена степень участия в написании этой пьесы известного белорусского деятеля Вацлава Ивановского, а также Анны и Эд-варда Сущинских.The article is devoted to the history of writing one of the first Belarusian plays «Mikhalka». Vatslav Ivanovsky, outstanding Belarusian cultural figure, Hanna Suschynskaya and Edvard Sushchynski, Belarusian dramatists, played the main role in the creation of this play

Хто напісаў адну з першых беларускіх п'ес «Міхалка»?

В статье рассмотрена история создания одной из первых белорусских пьес «Міхалка». Выявлена степень участия в написании этой пьесы известного белорусского деятеля Вацлава Ивановского, а также Анны и Эдварда Сущинских

Stress-overcoming behaviour of women with minor cardiac abnormalities

The purpose of this research was to determine stress-overcoming behaviour of women with minor cardiac abnormalities considering abnormality intensity. With the help of Toronto Alexithymia Scale, E. Heim`s system and S. Subbotin`s test 122 young women with different manifestation rates of the heart connective tissue dysplasia (minimal – basic group and moderate - comparison group) were examined (average age –21,46 ± 2,12 years). Significant dominance of adaptive coping strategies in all spheres was revealed when studying of stress-overcoming behaviour of healthy women with minor cardiac abnormalities of minimal intensity. Women of the comparison group used maladaptive coping-strategies in emotional and behavioural spheres more often comparing with clinically healthy women of the basic group. Significantly lower level of the stress resistance and higher alexithymia level were determined in the observed group with minor cardiac abnormalities of moderate intensity which has chosen maladaptive emotional and behavioural coping-strategies. The results are appropriate to consider for personalized arrangements for prevention of cardiovascular complications in patients with heart connective tissue dysplasia syndrome

Mathematical results for some α\displaystyle{\alpha} models of turbulence with critical and subcritical regularizations

In this paper, we establish the existence of a unique "regular" weak solution to turbulent flows governed by a general family of $\alpha$ models with critical regularizations. In particular this family contains the simplified Bardina model and the modified Leray-$\alpha$ model. When the regularizations are subcritical, we prove the existence of weak solutions and we establish an upper bound on the Hausdorff dimension of the time singular set of those weak solutions. The result is an interpolation between the bound proved by Scheffer for the Navier-Stokes equations and the regularity result in the critical case

Measurements of the SUSY Higgs self-couplings and the reconstruction of the Higgs potential

We address the issue of the reconstruction of the scalar potential of a two-Higgs doublet model having in mind that of the MSSM. We first consider the general CP conserving dim-4 effective potential. To fully reconstruct this potential, we show that even if all the Higgs masses and their couplings to the standard model particles are measured one needs not only to measure certain trilinear Higgs self-couplings but some of the quartic couplings as well. We also advocate expressing the Higgs self couplings in the mass basis. We show explicitly, that in the so-called decoupling limit, the most easily accessible Higgs self-couplings are given in terms of the Higgs mass while all other dependencies on the parameters of the general effective potential are screened. This helps also easily explain how, in the MSSM, the largest radiative corrections which affect these self couplings are reabsorbed by using the corrected Higgs mass. We also extend our analysis to higher order operators in the effective Higgs potential. While the above screening properties do not hold, we argue that these effects must be small and may not be measured considering the foreseen poor experimental precision in the extraction of the SUSY Higgs self-couplings.Comment: 25 pages, 3 figure

The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a

CONCLUSIONS: In various differentiated Drosophila cell types, we discovered the existence of peripheral heterochromatin, similar to that observed in mammals. Our findings support the model that peripheral heterochromatin matures enhancing the repression of unwanted genes as cells terminally differentiate.BACKGROUND: In most mammalian cell lines, chromatin located at the nuclear periphery is represented by condensed heterochromatin, as evidenced by microscopy observations and DamID mapping of lamina-associated domains (LADs) enriched in dimethylated Lys9 of histone H3 (H3K9me2). However, in Kc167 cell culture, the only Drosophilla cell type where LADs have previously been mapped, they are neither H3K9me2-enriched nor overlapped with the domains of heterochromatin protein 1a (HP1a).RESULTS: Here, using cell type-specific DamID we mapped genome-wide LADs, HP1a and Polycomb (Pc) domains from the central brain, Repo-positive glia, Elav-positive neurons and the fat body of Drosophila third instar larvae. Strikingly, contrary to Kc167 cells of embryonic origin, in neurons and, to a lesser extent, in glia and the fat body, HP1a domains appear to overlap strongly with LADs in both the chromosome arms and pericentromeric regions. Accordingly, centromeres reside closer to the nuclear lamina in neurons than in Kc167 cells. As expected, active gene promoters are mostly not present in LADs, HP1a and Pc domains. These domains are occupied by silent or weakly expressed genes with genes residing in the HP1a-bound LADs expressed at the lowest level