Aportaciones empresariales para un debate en torno al empleo

SEGUNDO PANEL: La Europa social en Euskad

La cuestión del sujeto en el pensamiento de Martin Heidegger.

Sin resume

UN FORUM SERIES – measuring progress through national action plans and sustainability reports

This blog was contributed by Verónica Aranzazu Zubía Pinto, Adviser of the Human Rights Division of the Chilean Ministry of Foreign Affairs. Strong political support The United Nations Guiding Principles on Business and Human Rights (UNGPs) arrived in 2011 to stay. They established an agenda that is constantly moving forward and will not pull back

Anticancer Activities of Meroterpenoids Isolated from the Brown Alga Cystoseira usneoides against the Human Colon Cancer Cells HT-29

Colorectal cancer (CRC) is one of the most common types of cancers and a leading cause of cancer death worldwide. The current treatment for CRC mainly involves surgery, radiotherapy, and chemotherapy. However, due to the side effects and the emergence of drug resistance, the search for new anticancer agents, pharmacologically safe and effective, is needed. In the present study, we have investigated the anticancer effects of eight algal meroterpenoids (AMTs, 1-8) isolated from the brown seaweed Cystoseira usneoides and their underlying mechanisms of action using HT-29, a highly metastatic human colon cancer cell line. All the tested meroterpenoids inhibited the growth of HT-29 malignant cells and were less toxic towards non-cancer colon cells, with the AMTs 1 and 5 exhibiting selectivity indexes of 5.26 and 5.23, respectively. Treatment of HT-29 cells with the AMTs 1, 2, 3, 4, 5, and 7 induced cell cycle arrest in G2/M phase and, in some instances, apoptosis (compounds 2, 3, and 5). Compounds 1-8 also exhibited significant inhibitory effects on the migration and/or invasion of colon cancer cells. Mechanistic analysis demonstrated that the AMTs 1, 2, 5, 6, 7, and 8 reduced phosphorylation levels of extracellular signal-regulated kinase (ERK) and the AMTs 2, 3, 4, 5, 7, and 8 decreased phosphorylation of c-JUN N-terminal kinase (JNK). Moreover, the AMTs 1, 2, 3, 4, 7, and 8 inhibited phosphorylation levels of protein kinase B (AKT) in colon carcinoma cells. These results provide new insights into the mechanisms and functions of the meroterpenoids of C. usneoides, which exhibit an anticancer effect on HT-29 colon cancer cells by inducing cell cycle arrest and apoptosis via the downregulation of ERK/JNK/AKT signaling pathways

Optical Fiber Sensor boosts aircraft engine monitoring

A reflective, intensity-modulated optical fiber sensor enables monitoring of tip clearance and tip timing in aircraft engines at low cost and high resolution.This work has been sponsored by the institutions Ministerio de Economía y Competitividad under project TEC2012-37983-C03; Gobierno Vasco/Eusko Jaurlaritza under projects IT664-13, S-PE13CA004, SPE13UN151, and S-PE12CA001; and by the University of the Basque Country (UPV/EHU) through program UFI11/16.Publicatio

Proyecto constructivo de acondicionamiento y mejora del dique norte de Castro Urdiales.

Grado en Ingeniería Civi

Plastic fiber-optic probes for characterizing fluidized beds in bubbling regime

Bubble measurements on a fluidized bed in bubbling regime using optical fibre probes (OFP) are reported. Comparisons between commercial pressure transducers (PT) measurements and OFP have also been carried out. OFP are able to detect smaller bubbles than the PT and reflect more localized phenomena in the bed.Publicad

La silenciosa política de retorno: la repatriación como fin último de las valoraciones psicológicas y las políticas migratorias

El artículo aborda la aplicación de la política migratoria desde una institución de protección a las infancias en Aguascalientes, México, centrándose en la elaboración de valoraciones psicológicas para determinar el destino de niñas, niños y adolescentes migrantes no acompañados, realizadas por funcionarios del Sistema Nacional para el Desarrollo Integral de la Familia. A través de la experiencia de las y los psicólogos se busca visibilizar la manera en que los procesos burocráticos perpetúan la violencia estructural e institucional, afectando el principio del interés superior de la niñez proveniente de Honduras, El Salvador y Guatemala. El estudio reveló que la forma en que se desarrollan los procesos de atención respalda una política no escrita que tiene como finalidad la repatriación.ITESO, A.C

Diseño hidráulico de alternativas para acondicionamiento y mejora del dique norte de Castro Urdiales

Grado en Ingeniería Civi