Developing nanotechnology for biofuel and plant science applications

This dissertation presents the research on the development of mesoporous silica based nanotechnology for applications in biofuels and plant science. Mesoporous silica nanoparticles (MSNs) have been the subject of great interest in the last two decades due to their unique properties of high surface area, tunable pore size and particle morphology. The robust nature of the silica framework is easily functionalized to make the MSNs a promising option for selective separations. Also, the independent channels that form the pores of MSN have been exploited in the use of particles as platforms for molecular delivery. Pore size and organic functionality are varied to identify the ideal adsorbent material for free fatty acids (FFAs). The resulting material is able to sequester FFAs with a high degree of selectivity from a simulated solution and microalgal oil. The recyclability and industrial implications are also explored. A continuation of the previous material, further tuning of MSN pore size was investigated. Particles with a smaller diameter selectively sequester polyunsaturated free fatty acids (PUFAs) over monounsaturated FFAs and saturated FFAs. The experimental results were verified with molecular modeling. Mesoporous silica nanoparticle materials with a pore diameter of 10 nm (MSN-10) were decorated with small gold nanoparticles. The resulting materials were shown to deliver proteins and DNA into plant cells using the biolistic method

A study of types and areas of casework treatment of mothers in a child guidance setting

Thesis (M.S.)--Boston Universit

Memory of Eric Stein

My memory of Eric Stein is of a teacher and mentor rather than a colleague. I will leave to others more qualified than I to describe his major contributions to the academic literature and teaching of European Community and public international law. When I entered Michigan Law School as a student in 1980, Eric had technically retired or at least transitioned to emeritus status. I say he had technically retired because his commitment to the law school community as a writer, teacher, and mentor to students never appeared to diminish. He still taught a number of classes and seminars, wrote extensively, and was more than generous with the time he spent with young law students like myself who professed an interest in international law

Biology of drives - A report of an NRP work session

Concepts and experimental data on biological mechanisms of drives, motivation, reinforcement, and learnin

Patient and Sample Identification. out of the Maze?

Background: Patient and sample misidentification may cause significant harm or discomfort to the patients, especially when incorrect data is used for performing specific healthcare activities. It is hence obvious that efficient and quality care can only start from accurate patient identification. There are many opportunities for misidentification in healthcare and laboratory medicine, including homonymy, incorrect patient registration, reliance on wrong patient data, mistakes in order entry, collection of biological specimens from wrong patients, inappropriate sample labeling and inaccurate entry or erroneous transmission of test results through the laboratory information system. Many ongoing efforts are made to prevent this important healthcare problem, entailing streamlined strategies for identifying patients throughout the healthcare industry by means of traditional and innovative identifiers, as well as using technologic tools that may enhance both the quality and efficiency of blood tubes labeling. The aim of this article is to provide an overview about the liability of identification errors in healthcare, thus providing a pragmatic approach for diverging the so-called patient identification crisis

Finding the Middle Path Between Dependence and Autonomy: Recent Trainee Experiences in Dialectical Behavior Therapy Supervision

Originally published in DBT Bulletin Volume 3, Issue 1 pages 28-32 (2020). The DBT Bulletin is published by DBT California

Age comparison of treatment adherence with antipsychotic medications among individuals with bipolar disorder

Background Few studies have evaluated medication adherence among older vs younger individuals with bipolar disorder (BPD). We compared adherence with antipsychotic medication among older (age 60 and older) and younger individuals using a large case registry ( n  = 73,964). Methods Adherence was evaluated using the medication possession ratio (MPR) for patients receiving antipsychotic medication. Results Twenty six thousand five hundred and thirty younger individuals (mean age 46.9) and 6,461 older individuals (mean age 69.2) were prescribed antipsychotic medication. Among older individuals, 61.0% ( n  = 3,350) were fully adherent, while 19.0% ( n  = 1,043) were partially adherent and 20.0% ( n  = 1,098) were non-adherent. Among younger individuals, 49.5% ( n  = 10,644) were fully adherent, while 21.8% ( n  = 4,680) were partially adherent, and 28.7% ( n  = 6,170) were non-adherent. As with younger patients, comorbid substance abuse and homelessness predicted non-adherence among older patients with BPD. Conclusion Older individuals with BPD were more adherent with antipsychotic medications compared to younger individuals. However, a substantial proportion (approximately 39%) of older patients with BPD still have difficulties with adherence. Copyright © 2007 John Wiley & Sons, Ltd.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/57370/1/1777_ftp.pd

Who Receives Outpatient Monitoring During High-Risk Depression Treatment Periods?

To examine the intensity of monitoring received by important patient subgroups during high-risk periods (the 12 weeks after psychiatric hospitalization and after new antidepressant starts).Retrospective secondary analysis of data from the Veterans Affairs (VA) National Registry for Depression using patients aged 65 and older receiving depression treatment from 1999 to 2004.VA healthcare system.VA patients in depression treatment between April 1, 1999, and September 30, 2004, who had psychiatric inpatient stays (n=73,137) or new antidepressant starts (n=421,536).The relationship between the number of outpatient visits for each group and patient characteristics in the 12-week period after psychiatric hospitalizations and antidepressant starts.The characteristic associated with significantly lower rates of monitoring for both high-risk treatment periods was aged 65 and older. White race and living in the south or northeast were also associated with significantly lower rates of monitoring after new antidepressant starts and inpatient stays, respectively. Substance abuse disorders were associated with greater monitoring after both types of depression events but did not seem to interact with other patient characteristics in determining levels of monitoring.VA patients who are older, white, and living in the south or northeast receive less-intensive monitoring during high-risk treatment periods for suicide. This is of concern, given that older patients appear to be at higher risk for suicide, particularly after inpatient stays, and may need particular attention during this time frame. Adapted interventions and proactive outreach may be needed that target this patient group.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79052/1/j.1532-5415.2010.02810.x.pd

Strong Military Families Intervention Enhances Parenting Reflectivity And Representations In Families With Young Children

Military families face many challenges due to deployment and parental separation, and this can be especially difficult for families with young children. The Strong Military Families (SMF) intervention is for military families with young children, and consists of two versions: the Multifamily Group, and a Home‐based psychoeducational written materials program. The Multifamily Group was designed to enhance positive parenting through both educational components and in vivo feedback and support during separations and reunions between parents and children (n = 78 parents). In the present study, we examine parenting reflectivity and mental representations in mothers versus fathers in military families, service members versus civilian spouses/parenting partners, and before versus after participation in the SMF Multifamily Group and Home‐based interventions. Parenting reflectivity and mental representations were coded from the Working Model of the Child Interview (WMCI; C.H. Zeanah & D. Benoit, 1995). Results suggest that neither parenting reflectivity nor WMCI typology differs between mothers and fathers in military families, or between service members and civilian parenting partners. Furthermore, there was substantial stability in parenting reflectivity and WMCI typology from baseline to posttest, but participation in the Multifamily Group, relative to Home‐based, was associated with improvements in both parenting reflectivity and WMCI ratings from baseline to postintervention.RESUMENLas familias militares enfrentan muchos retos debido a las distantes asignaciones de servicio y la separación de los padres, lo cual puede ser específicamente difícil para familias con niños pequeños. La intervención Familias Militares Fuertes (SMF) es para familias militares con niños pequeños y consta de dos versiones: un Grupo Múltiple de Familias y un programa sicoeducativo de materiales escritos con base en casa. El Grupo Múltiple de Familias se diseñó para mejorar la crianza positiva tanto a través de componentes educativos como de reacciones y apoyo en vivo durante las separaciones y reuniones entre padres y niños (n = 78 padres). En el presente estudio, examinamos el poder de reflexión sobre la crianza y las representaciones mentales en mamás vs. papás en familias militares, miembros del servicio militar vs. cónyuges civiles/parejas conyugales en la crianza, y antes vs. después de la participación en el Grupo Múltiple de Familias SMF y en las intervenciones con base en casa. El poder de reflexión sobre la crianza y las representaciones mentales se codificaron usando el Modelo de Trabajo de la Entrevista del Niño –WMCI‐ (Zeanah y Benoit, 1995). Los resultados sugieren que ni el poder de reflexión ni la tipología del WMCI difieren entre mamás y papás en familias militares, o entre miembros del servicio militar y sus parejas conyugales civiles en la crianza. Es más, se dio una estabilidad de importancia en el poder de reflexión y la tipología WMCI entre el punto de referencia y la examinación posterior, pero la participación en el Grupo Múltiple de Familias, en relación con la intervención en casa, se asoció con mejoras tanto en el poder de reflexión como en los puntajes WMCI entre el punto de referencia y la intervención posterior.RÉSUMÉLes familles de militaires font face à de nombreux défis du fait des déploiements et de la séparation parentale, et cela peut s’avérer particulièrement difficile pour les familles avec de jeunes enfants. L’intervention Familles Militaires fortes (ici abrégé en français FMF, SMF en anglais, pour Strong Military Families) est destinée aux familles de militaires avec de jeunes enfants et consiste en deux versions: un Groupe Multifamilial, et une intervention à domicile avec programme de matériel psychoéducatif écrit. Le Groupe Multifamilial a été conçu afin de mettre en valeur le parentage positif à travers des composantes éducatives et du feedback in vivo et du soutien durant les séparations et les réunions entre les parents et les enfants (n = 78 parents). Dans cette étude nous examinons la réflectivité de parentage et les représentations mentales chez les mères et les pères de familles de militaires, les membres du service comparés aux épouses civiles et aux partenaires de parentage civils, et avant par rapport à après la participation au Groupe Multifamilial FMF et les interventions à domicile. La réflectivité de parentage et les représentations mentales ont été codées à partir du Modèle de Travail de l’Entretien de l’Enfant (Zeanah & Benoit, 1995). Les résultats suggèrent que ni la réflectivité de parentage ni le Modèle de Travail de l’Entretien de l’Enfant ne diffèrent entre les mères et les pères dans les familles militaires ou entre les membres du service et les partenaires de parentage civils. De plus il y avait une stabilité importante dans la réflectivité de parentage et la typologie du Modèle de Travail de l’Entretien de l’Enfant du niveau de référence jusqu’après le test, mais la participation au Groupe Multifamilial, par rapport à la participation à domicile, était liée à des améliorations dans à la fois la réflectivité de parentage et les scores du Modèle de Travail de l’Entretien de l’Enfant du niveau de référence à après l’intervention.ZUSAMMENFASSUNGMilitärische Familien stehen durch den Einsatz und die Trennung der Eltern vor vielen Herausforderungen, was besonders für Familien mit Kleinkindern schwierig sein kann. Die Intervention „Strong Military Families“ (SMF) richtet sich an Militärfamilien mit Kleinkindern und besteht aus zwei Versionen: Aus einer Mehrfamiliengruppe und einem psychoedukativen schriftlichen Materialprogramm für Zuhause. Die Mehrfamiliengruppe wurde entwickelt, um die positive Elternschaft sowohl durch pädagogische Komponenten als auch durch in vivo Feedback und Unterstützung bei Trennungen und Wiedervereinigungen zwischen Eltern und Kindern (n = 78 Eltern) zu fördern. In der vorliegenden Studie untersuchen wir die Reflektivität und mentalen Repräsentationen von Eltern bei Müttern vs. Vätern in militärischen Familien, Dienstmitgliedern vs. zivilen Ehepartnern/Erziehungspartnern und vor vs. nach der Teilnahme an der SMF Mehrfamiliengruppe und psychoedukativen Intervention Zuhause. Die elterliche Reflektivität und mentalen Repräsentationen wurden aus dem “Working Model of the Child Interview” (WMCI; Zeanah & Benoit, 1995) kodiert. Die Ergebnisse deuten darauf hin, dass sich weder die elterliche Reflektivität noch die Typologie der WMCI zwischen Müttern und Vätern in Militärfamilien oder zwischen Dienstmitgliedern und zivilen Ehepartnern unterscheiden. Außerdem gab es eine beträchtliche Stabilität in der elterlichen Reflektivität und WMCI‐Typologie vom Beginn der Untersuchungen bis zum Post‐Test, aber die Teilnahme an der Mehrfamiliengruppe, im Vergleich zur psychoedukativen Intervention Zuhause, war mit Verbesserungen sowohl in der elterlichen Reflektivität als auch in der WMCI‐Bewertung vom Untersuchungsbeginn zur Post‐Intervention verbunden.抄録強い軍人家族介入 The Strong Military Families が、 幼い子どものいる家族における育児の内省性 Reflectivity と表象を増強する軍人家族は配属や親との分離のために多くの困難に直面する。そしてこれは幼い子どものいる家族には特に困難になり得る。強い軍人家族The Strong Military Families (SMF)介入は、幼い子どものいる軍人家族のためのもので、2つの型がある。それらは、複数家族グループと資料を用いて家庭で行う心理教育的プログラムである。複数家族グループは、教育的な要素および親子の分離と再会のその場でのフィードバックと支援の両者を通して、ポジティブな育児を増強するようにデザインされた(n = 78人の親)。この研究では、私たちは、軍人家族の母親対父親、軍人対民間人の配偶者/養育パートナー、そしてSMF複数家族グループと家庭での介入に参加前対参加後において、育児の内省性と心的表象を調査した。育児の内省性と心的表象は、the Working Model of the Child Interview (Zeanah & Benoit, 1995) によってコード化された。結果から、軍人家族の母親と父親、あるいは軍人と民間人の養育パートナーの間に、育児の内省性あるいはWMCIタイプについて違いは示されなかった。さらに、基準線からテスト後にかけて、育児の内省性およびWMCIタイプにかなりの安定性があったが、家庭におけるプログラムに比べて、複数家族グループに参加することは、育児の内省性およびWMCI評価の両者の基準線から介入後への改善と関連していた。摘要強大軍人家庭干預增強在有子女家庭中的育兒反思能力和表現由於軍事部署和父母在不同地方居住, 軍人家庭面臨許多挑戰, 這些挑戰對於有小孩的家庭尤其嚴重。強大軍人家庭干預 (SMF) 是為有小孩的軍人家庭進行的干預, 包括兩個版本: 一個多家庭小組和一個家庭式的心理教育書面材料計劃。多家庭小組旨在通過教育丶反饋和支持, 在父母與子女 (78名父母) 的分離和團聚期間, 加強積極的父母教養。在本研究中, 我們考察在軍人家庭丶服務人員與平民配偶/養育夥伴的父母, 以及參與 SMF 多家庭小組和家庭式干預前後的父母反思和心理表徵。我們以兒童訪談的工作模式 (Zeanah&Benoit, 1995), 編碼父母反思能力和心理表徵。結果表明, 在軍人家庭父母之間, 或服務人員和平民養育夥伴之間, 父母反思能力和WMCI類型學並無不同。此外, 從基線到測試後, 父母反思能力和WMCI類型相當穩定, 但和家庭式干預相比, 多家庭小組的參與, 與從基線到干預後的父母反思能力和WMCI評分之改善相關。ملخصالتدخل القوى عند العائلات العسكرية يعزز الأداء التأملي الوالدي والتمثيلات الذهنية في الرعاية الوالدية للعائلات تجاه أطفالهم الصغارالعائلات العسكرية تواجه كثيرا من التحديات بسبب حركات التنقل العسكري والانفصال بين الوالدين وهذا يكون أشد صعوبة بالنسبة للعائلات ذوي الأطفال الصغار. التدخل القوي للعائلات العسكرية (SMF) هو برنامج يتكون من جانبين: مجموعة متعددة الأسر وبرنامج منزلي للمواد التعليمية النفسية المكتوبة. تم تشكيل المجموعة متعددة الأسر لتعزيز الرعاية الوالدية الإيجابية من خلال مكونات تعليمية وتغذية مرتدة ودعم أثناء فترات انفصال الأسر ولم الشمل بين الوالدين والأطفال (n = 78). في الدراسة الحالية نستخدم الأداء التأملي الوالدي والتمثيلات الذهنية عند الأمهات مقابل الآباء في الأسر العسكرية وأفراد الخدمة بالمقارنة مع الأزواج والوالدين المدنيين وكذلك المقارنة بين قبل وبعد المشاركة في برنامج (SMF). تم ترميز الأداء التأملي الوالدي والتمثيلات الذهنية من خلال النموذج العامل للمقابلة الشخصية مع الطفل (زينة وبينوا 1995). تشير النتائج إلى عدم اختلاف الأداء التأملي الوالدي ونمط النموذج العامل لمقابلة الطفل (WMCI) بين الآباء والأمهات في الأسر العسكرية أو بين أفراد الخدمة والأزواج والآباء المدنيين. بالإضافة إلى ذلك كان هناك استقرار جوهري في الأداء التأملي الوالدي ونمط النموذج العامل بين خط البداية والاختبار البعدي ولكن المشاركة في مجموعة متعددة الأسر بالمقارنة مع البرنامج المنزلي كانت مقترنة بتحسن في كل من الأداء التأملي الوالدي وتقييمات (WMCI) بين خط البداية وتدخل الاختبار البعدي.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141683/1/imhj21690_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141683/2/imhj21690.pd