Toward a Phenomenology of Perception

Paper by Robert S. Tragesse

Following the Money: The Responses of Political Actors to Betting Market Conditions and Other Measures of Campaign Competitiveness

This paper sets out to quantify whether actors who contribute independent expenditures in support of U.S. House candidates do so in a strategic way. Specifically, whether more money is spent on candidates that are perceived to be in more competitive elections. It also discusses different sources of information from which spenders can discover whether a candidate is competitive. Data from political betting markets are utilized in a novel setting to support the conclusions. I expected that political expenditures will be significantly related to measures of competitiveness, and that betting markets would be a significant source of that information. I used a generalized additive model to isolate the relationship between the implied competitiveness of a candidate based on betting market data and the amount of independent expenditure supporting them that they received, controlling for various individual candidate effects and other sources of information regarding competitiveness. I found the expected relationship, but that betting markets were not a significant source of information when making spending decisions.No embargoAcademic Major: EconomicsAcademic Major: Political Scienc

Modeling of tethered satellite formations using graph theory

Tethered satellite formations have recently gained increasing attention due to future mission proposals. Several different formations have been investigated for their dynamic properties and control schemes have been suggested. Formulating the equations of motion and investigation which geometries could form stable formations in space are cumbersome when done at a case to case basis, and a common framework providing a basic model of the dynamics of tethered satellite formations can therefore be advantageous. This paper suggests the use of graph theoretical quantities to describe a tethered satellite formation and proposes a method to deduce the equations of motion for the attitude dynamics of the formation in a compact form. The use of graph theory and Lagrange mechanics together allows a broad class of formations to be described using the same framework. A method is stated for finding stationary configurations and an upper limit of their number is determined. The method is shown to be valid for general tethered satellite formations that form a tree structure.ISSN:0094-576

How Position of Reading Questions Affects the Reading Comprehension of High and Low Ability Readers

This study investigates the optimum placement of reading questions in textbooks. Is it better to have reading questions embedded in chapters or placed at the end of chapters? One independent variable is reading question placement (embedded vs. end). Another independent variable is reading comprehension ability (higher vs. lower). Participants read a chapter from a statistics book, listened to stories as a distractor task, and then answered three types of questions about the statistics chapter. The dependent variable is the percent correct for each question type. Target questions tested the same content as a previous reading question. Related questions tested similar content. Non-target questions tested unrelated content. We will analyze our data with three 2 x 2 factorial ANOVAs. We expect embedded questions will help lower-ability readers on target and related questions. Further, embedded questions will hurt the performance of higher-ability readers on non-target questions. Higher and lower comprehenders differ in their ability to suppress irrelevant information. Embedded questions facilitate suppression processes by highlighting specific content in the reading. However, for high comprehenders who already suppress irrelevant information effectively, embedded questions may lead to “over suppression,” causing non-target information to be processed less well

Survivors of Congenital Diaphragmatic Hernia Repair Face Barriers to Long-Term Follow-Up Care

BACKGROUND: Congenital diaphragmatic hernia (CDH) carries high morbidity and mortality, and survivors commonly have neurodevelopmental, gastrointestinal, and pulmonary sequela requiring multidisciplinary care well beyond repair. We predict that following hospitalization for repair, CDH survivors face many barriers to receiving future medical care. METHODS: A retrospective review was conducted of all living CDH patients between ages 0 to 12 years who underwent repair at Riley Hospital for Children (RHC) from 2010 through 2019. Follow-up status with specialty providers was reviewed, and all eligible families were contacted to complete a survey regarding various aspects of their child's care, including functional status, quality of life, and barriers to care. Bivariate analysis was applied to patient data (P < 0.05 was significant) and survey responses were analyzed qualitatively. RESULTS: After exclusions, 70 survivors were contacted. Thirty-three (47%) were deemed lost to follow up to specialist providers, and were similar to those who maintained follow-up with respect to defect severity type (A-D, P = 0.57), ECMO use (P = 0.35), number of affected organ systems (P = 0.36), and number of providers following after discharge (P = 0.33). Seventeen (24%) families completed the survey, of whom eight (47%) were deemed lost to follow up to specialist providers. Families reported distance and time constraints, access to CDH-specific information and care, access to CDH-specific resources, and access to healthcare as significant barriers to care. All respondents were interested in a multidisciplinary CDH clinic. CONCLUSIONS: CDH survivors require multidisciplinary care beyond initial repair, but attrition to follow-up after discharge is high. A multidisciplinary CDH clinic may address caregivers' perceived barriers

Viral Double-Strand RNA-Binding Proteins Can Enhance Innate Immune Signaling by Toll-Like Receptor 3

Toll-like Receptor 3 (TLR3) detects double-stranded (ds) RNAs to activate innate immune responses. While poly(I:C) is an excellent agonist for TLR3 in several cell lines and in human peripheral blood mononuclear cells, viral dsRNAs tend to be poor agonists, leading to the hypothesis that additional factor(s) are likely required to allow TLR3 to respond to viral dsRNAs. TLR3 signaling was examined in a lung epithelial cell line by quantifying cytokine production and in human embryonic kidney cells by quantifying luciferase reporter levels. Recombinant 1b hepatitis C virus polymerase was found to enhance TLR3 signaling in the lung epithelial BEAS-2B cells when added to the media along with either poly(I:C) or viral dsRNAs. The polymerase from the genotype 2a JFH-1 HCV was a poor enhancer of TLR3 signaling until it was mutated to favor a conformation that could bind better to a partially duplexed RNA. The 1b polymerase also co-localizes with TLR3 in endosomes. RNA-binding capsid proteins (CPs) from two positive-strand RNA viruses and the hepadenavirus hepatitis B virus (HBV) were also potent enhancers of TLR3 signaling by poly(I:C) or viral dsRNAs. A truncated version of the HBV CP that lacked an arginine-rich RNA-binding domain was unable to enhance TLR3 signaling. These results demonstrate that several viral RNA-binding proteins can enhance the dsRNA-dependent innate immune response initiated by TLR3

Two Decades Using Stentless Porcine Aortic Root in Right Ventricular Outflow Tract Reconstruction

Background The stentless porcine aortic root prosthesis (SPAR) has been described as a suitable valve for right ventricular outflow tract reconstruction (RVOTR). Indiana University Methodist Hospital in Indianapolis, Indiana began using this valve for RVOTR in 1998. This study reports medium-term to late- term outcomes of the valve in the pulmonary position. Methods A retrospective chart review was conducted of patients older than 18 years of age who underwent RVOTR with a SPAR between April 2000 and October 2019. Primary outcomes included survival and freedom from any valvular reintervention. Secondary outcomes included endocarditis and conduit dysfunction detected by routine echocardiography or cardiac magnetic resonance imaging. Results A total of 135 patients underwent RVOTR with a SPAR at a median age of 32.4 years (range, 18 to 71 years). Of these patients, 129 had previous surgery. Indications included pulmonary insufficiency (90.4%), stenosis (34.8%), endocarditis (7.4%), and carcinoid (4.4%). Median follow-up was 2.97 years (interquartile range, 0.6 to 8.0 years). Overall survival was 93.3%, with 3 perioperative death and 6 late deaths. Endocarditis developed in 4 patients (2.9%), 2 of whom required reoperation. Progressive conduit degradation was evident at 10 years, with 22.2% and 7.7% having moderate stenosis and insufficiency, respectively. Eight (5.9%) reinterventions included 2 surgical replacements, 3 percutaneous replacements, and 3 balloon valvuloplasties at means of 8.5, 7.4, and 2.2 years, respectively. Overall freedom from reintervention at 1, 5, and 10 years was 99.1%, 94.7% and 90.7%, respectively. Conclusions In this large, single-institution experience with a long follow-up period, use of the SPAR demonstrated excellent midterm to long-term durability, low rates of endocarditis, and high freedom from reintervention