Park, Aesoon

Sher, Kenneth J

Tragesser, Sarah L

Trull, Timothy J

Digital Commons@Becker

Washington University School of MedicineDigital Commons@BeckerPosters 2006: Alcohol and Tobacco Dependence: fromBench to Bedside2006Personality disorder symptoms and drinkingmotives as predictors of alcohol consumption andconsequences.Sarah L. TragesserUniversity of Missouri - ColumbiaAesoon ParkUniversity of Missouri - ColumbiaKenneth J. SherUniversity of Missouri - ColumbiaTimothy J. TrullUniversity of Missouri - ColumbiaFollow this and additional works at: http://digitalcommons.wustl.edu/guzeposter2006Part of the Medicine and Health Sciences CommonsThis Poster is brought to you for free and open access by the 2006: Alcohol and Tobacco Dependence: from Bench to Bedside at DigitalCommons@Becker. It has been accepted for inclusion in Posters by an authorized administrator of Digital Commons@Becker. For more information,please contact engeszer@wustl.edu.Recommended CitationTragesser, Sarah L.; Park, Aesoon; Sher, Kenneth J.; and Trull, Timothy J., "Personality disorder symptoms and drinking motives aspredictors of alcohol consumption and consequences." (2006). Posters. Paper 5 Samuel B. Guze Symposium on Alcoholism.http://digitalcommons.wustl.edu/guzeposter2006/5PERSONALITY DISORDER SYMPTOMS AND DRINKING MOTIVES AS PREDICTORS OF ALCOHOL CONSUMPTION AND CONSEQUENCES.Sarah L. Tragesser, Aesoon Park, Kenneth J. Sher, & Timothy J. TrullUniversity of Missouri-Columbia and the Midwest Alcoholism Research CenterIntroduction Research shows high comorbidity between certain Personality Disorders (PDs) and Alcohol Use Disorders (AUDs).There are three DSM-IV personality disorder clusters: Cluster A(odd-eccentric), Cluster B (dramatic-erratic-emotional), and Cluster C(anxious-fearful). Drinking to cope with negative emotions (coping motives) and drinking to enhance positive emotions (enhancement motives) are predicted to be most relevant for explaining the relationship between Cluster B PDs and alcohol problems. Drinking motives are thought to be the proximal mechanisms through which traits of affective instability and impulsivity operate. Cluster B PDs are believed to be characterized by high levels of affective instability and impulsivity. We tested whether coping and enhancement drinking motives mediated the relations between Personality Disorder (PD) symptoms assessed via the SIDP-IV and alcohol consumption and problems. MethodParticipantsParticipants included 155 male and 197 female participants in a longitudinal study of problems associated with alcohol and other substances at each of seven waves of assessment across 16 years, beginning in their freshman year of college (Wave 0). Only data from years 11 and 16 were used in the present study.Participants were 28.95 (SD = 1.02) years of age at Year 11 and 34 (SD = .83) at Year 16. 46% male, 90% Caucasian.Materials & ProcedureAUD Diagnoses. For our criterion measure of alcohol use diagnoses, we assessed past year DSM-IV AUD (abuse or dependence) and antisocial personality disorder at Years 11 and 16 using the Diagnostic Interview Schedule, Version IV (DIS-IV). Personality Disorder Symptoms. DSM-IV personality disorder symptoms were assessed in each participant by administering the Structured Interview for DSM-IV Personality (SIDP-IV) at Year 11. Drinking Motives. Coping included 5 items such as “drink to forget about your problems”. Enhancement included 5 items such as “drink because it’s exciting” Items were rated on a scale from 0 (“Strongly Agree”) to 3 (“Strongly Disagree”). Other Alcohol-Related Variables. Measures of quantity-frequency of alcohol use, heavy drinking, measures of types of negative consequences from alcohol, and a measure of alcohol dependence features were included in questionnaire format. Analyses Path analyses were conducted to test the hypothesis that the relation between Year 11 Cluster B symptoms and Year 16 alcohol-related variables was mediated by Year 11 drinking motives (see Figure).  Symptoms associated with other PD Clusters (A and C), were also modeled.  Separate models were estimated for each dependent alcohol-related variable.ResultsCross-sectional Mediation (Year 11 only) Enhancement motives partially mediated the relation between Cluster B symptoms and alcohol quantity/frequency, heavy drinking, total consequences, mild consequences, and dependence features (see Table).  Coping motives partially mediated the relation between Year Cluster B symptoms and moderate consequences, social consequences, and dependence features. With the exception of AUDs, these effects carried over to Year 16, operating through Year 11 alcohol variables. Prospective Mediation (to Year 16) Enhancement motives partially mediated the relationship between Year 11 Cluster B symptoms and Year 16 alcohol consequences, dependence features, and AUD diagnosis above and beyond prior levels of alcohol consequences, dependence, or presence of a diagnosis.. The present research was supported by NIH grants T32 AA13526 and AA13987 to Kenneth J. Sher and the NIMH grant MH52695 awarded to Timothy J. Trull. Time 1 Variables Time 2Cluster AsymptomsCluster BsymptomsCluster CsymptomsEnhancementMotivesCoping MotivesAlcohol-Related VariableYear 11Alcohol-RelatedVariableYear 16Conclusions As predicted, coping and enhancement motives partially mediate the relation between Cluster B symptoms and alcohol-related variables. Consistent with previous research, coping motives were relevant to consequences and dependence features. Enhancement motives predicted subsequent AUD diagnosis. Impulsivity may be the underlying trait in the relation between Cluster B PDs and alcohol problems.________________________________________________________________________Variable Cross-sectional Prospective EffectEffect (Year 11) (Year 16)_____________________________________ ___________________________________Quant/Freq DrinkingSex -.20*** -.04Enhancement .27*** -.09Coping .03 .01Cluster A -.12* -.07**Cluster B .21** .00Cluster C -.05 .03Q/F Year 11 -- .65**________________________________________________________________________Heavy DrinkingSex -.19*** -.06Enhancement .30*** .11Coping -.03 .04Cluster A -.11** -.08**Cluster B .26*** .06Cluster C -.09* -.00HD Year 11 -- .48***_____________________________________ ___________________________________Total ConsequencesSex .02 -.05Enhancement .18*** .18***Coping .16** .01Cluster A -.12** -.04Cluster B .30*** .07Cluster C -.05 -.06T Con Year 11 -- .35***________________________________________________________________________Mild ConsequencesSex -.09* .03Enhancement .39*** .14**Coping .10 .05Cluster A -.11* -.05Cluster B .34*** .04Cluster C -.04 -.02Mld Con Year 11 -- .70***________________________________________________________________________Moderate ConsequencesSex .00 .04Enhancement -.09 .10**Coping .27*** .02Cluster A .01 .09Cluster B .39*** .18*Cluster C -.05 -.06Mod Con Year 11 -- .49***_____________________________________ ___________________________________Social ConsequencesSex -.09 -.01Enhancement .02 -.05Coping .16** .03Cluster A .17 -.05Cluster B .15* .19*Cluster C -.12** -.05Soc Con Year 11 -- .52***________________________________________________________________________Dependence FeaturesSex .04 .08Enhancement .16** .13**Coping .22** .07Cluster A .00 -.05Cluster B .35*** .09Cluster C -.05 -.09Depen Year 11 -- .44**________________________________________________________________________AUDSex -.11 -.01Enhancement .37*** .29**Coping .10 .06Cluster A -.03 -.10Cluster B .32*** .25**Cluster C -.03 -.10AUD Year 11 -- .22________________________________________________________________________ Note. N = 352. * p < .05, ** p < .01, *** p < .001. Direct Paths From Sex, Drinking Motives, and Personality Disorder Symptom Counts to Alcohol-Related Variables at Years 11 & 16, Controlling for Indirect Paths

Personality disorder symptoms and drinking motives as predictors of alcohol consumption and consequences.

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Personality disorder symptoms and drinking motives as predictors of alcohol consumption and consequences.

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