Amadis : tragédie en musique / les paroles son de Quinault. Et la musique de Lully

Teil von: Recueil des opéra : Tome troisième ;

Interpreting the Outsider Tradition in British European Policy Speeches from Thatcher to Cameron

The article investigates how British European policy thinking has been informed by what it identifies as an ‘outsider’ tradition of thinking about ‘Europe’ in British foreign policy dating from imperial times to the presen. The article begins by delineating five phases in the evolution of the outsider tradition through a survey of the relevant historiography back to 1815. The article then examines how prime ministers from Margaret Thatcher to David Cameron have looked to various inflections of the outsider tradition to inform their European discourses. The focus in the speech data sections is on British identity, history and the realist appreciation of international politics that informed the leaders’ suggestions for EEC/EU reform. The central argument is that historically informed narratives such as those making up the outsider tradition do not determine opinion-formers’ outlooks, but that they can be deeply impervious to rapid change

Gladstone and Scott: Family, identity, and nation

In the 175 years since his death, Walter Scott has regularly been hailed as an influence by politicians. Amongst the poet-novelist's nineteenth-century political admirers, William Ewart Gladstone was possibly the most ardent, genuine, and significant. Scott's poems and novels were amongst the earliest texts Gladstone read; he read no works (in English), except the Bible, so consistently or completely over such a length of time. They offered him a plethora of inspirations, ideas, and language, which he imbibed and appropriated into his public and private lives. His concept of self, his understanding of family, and his sense of home, were all forged and conducted within a Scottian frame of reference. Scott's life and works also crucially influenced Gladstone's political understanding of the Scottish nation and its people, and his conception of how he could best serve their political interests. This article casts new light on an important and influential relationship in Gladstone's life, establishing that it was neither the superficial and recreational association some have described, nor simply a ploy of an astute politician. The article falls into three parts. The first elucidates how Gladstone's consumption of Scott's writings was seminal in the formation of his private identity, both individual and familial. The second explains how Gladstone's readings of Scott fitted into the specific and serious character of his other reading and knowledge-gathering, and the third shows how the details of Gladstone's response to Scott related to the broader intellectual and cultural context of his public life. By placing Gladstone within his Scottish context, this article shows how frequently and significantly his private and public worlds intersected

Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing

OBJECTIVE: Hypothalamic glucose sensing (HGS) initiates insulin secretion (IS) via a vagal control, participating in energy homeostasis. This requires mitochondrial reactive oxygen species (mROS) signaling, dependent on mitochondrial fission, as shown by invalidation of the hypothalamic DRP1 protein. Here, our objectives were to determine whether a model with a HGS defect induced by a short, high fat-high sucrose (HFHS) diet in rats affected the fission machinery and mROS signaling within the mediobasal hypothalamus (MBH). METHODS: Rats fed a HFHS diet for 3 weeks were compared with animals fed a normal chow. Both in vitro (calcium imaging) and in vivo (vagal nerve activity recordings) experiments to measure the electrical activity of isolated MBH gluco-sensitive neurons in response to increased glucose level were performed. In parallel, insulin secretion to a direct glucose stimulus in isolated islets vs. insulin secretion resulting from brain glucose stimulation was evaluated. Intra-carotid glucose load-induced hypothalamic DRP1 translocation to mitochondria and mROS (H2O2) production were assessed in both groups. Finally, compound C was intracerebroventricularly injected to block the proposed AMPK-inhibited DRP1 translocation in the MBH to reverse the phenotype of HFHS fed animals. RESULTS: Rats fed a HFHS diet displayed a decreased HGS-induced IS. Responses of MBH neurons to glucose exhibited an alteration of their electrical activity, whereas glucose-induced insulin secretion in isolated islets was not affected. These MBH defects correlated with a decreased ROS signaling and glucose-induced translocation of the fission protein DRP1, as the vagal activity was altered. AMPK-induced inhibition of DRP1 translocation increased in this model, but its reversal through the injection of the compound C, an AMPK inhibitor, failed to restore HGS-induced IS. CONCLUSIONS: A hypothalamic alteration of DRP1-induced fission and mROS signaling in response to glucose was observed in HGS-induced IS of rats exposed to a 3 week HFHS diet. Early hypothalamic modifications of the neuronal activity could participate in a primary defect of the control of IS and ultimately, the development of diabetes.Rôle des connexines astrocytaires dans le mécanisme de détection hypothalamique du glucose : implication sur le contrôle nerveux du métabolisme énergétiqu

Winston Churchill and the Aristocracy

Historical interest in Winston Churchill–which shows no signs of abating–has focused on what he was, as well as on what he did. Was Churchill the “last lion” of a dying English social order, or a new classless trans-Atlantic man? His official biographer, Martin Gilbert, has avoided this issue, but others have proffered contrasting opinions. In 1962 Anthony Sampson wrote: “Churchill has never taken very kindly to the aristocracy from which he sprung and even in his old age he has preferred the..

“So Shall She Now the Softest Coulours Chuse/To Paint thy Fate & Shadow out thy Woes”

This article will explore the ways in which literary forms empower emotional response to public events, using as a case study the wide range of literary texts – published and circulated in manuscript – inspired by the notorious Abergavenny scandal of 1729. Lady Abergavenny’s beauty, adultery and death, followed by a trial in which her husband was awarded a staggering £10,000 in compensation, stimulated poetry, drama and opera, giving voice to desire, remorse, pity, despair and contempt. Drama and poetry intersect in their treatment of the scandal, and while poetry offers its writers and readers an opportunity to explore a single viewpoint, and to circulate it privately, drama re-imagines the causes and conversations, and exposes them to public judgment. The alternating prose and verse of opera thus offer us a self-contained sample of the uses of different literary genres in expressing emotion and presenting the social and moral debates provoked by the affair

Armida

monografi

Die verbuhlte Mutter oder die veruneinigte Liebhaber : ein Lust-Spiel in Fünf Handlungen

aus dem Französischen des Monsieur Quinault ins Teutsche übersetzet von Benignus PfeufferAutopsie nach Ex. der ULB Sachsen-AnhaltVorlageform des Erscheinungsvermerks: Wetzlar, gedruckt bey George Ernst Winckler. - Erscheinungsjahr ermittel in: WBI, DbA I 952,118-12