Implementierung von Reglern und Steuerelementen für ein Android-basiertes E-Learning-Spiel für Smartphones

E-Learning spielt in der Bildung eine immer wichtigere Rolle und ermöglicht es Inhalte spielerisch und schnell zu erfassen. Aus diesem Grund wird in dieser Arbeit ein Spiel auf Basis des mobilen Betriebssystems Android konzipiert und implementiert, mit dem die Inhalte der Vorlesungen des Instituts für Systemtheorie und Regelungstechnik verdeutlicht werden sollen. Inhaltlich wurde das Thema in zwei Studienarbeiten aufgeteilt. Der Schwerpunkt dieser Arbeit liegt auf der Umsetzung der regelungstechnischen Modelle. Nach einer kurzen Einleitung wird in dieser Arbeit ein Überblick über die notwendigen Grundlagen der Regelungstechnik und dem Betriebssystem Android gegeben. Anschließend werden neben den verschiedenen Reglerentwurfsverfahren die genutzten Konzepte und Entwurfsverfahren der Softwaretechnik vorgestellt. Im anschließenden Implementierungskapitel wird vor allem auf die konkrete Implementierung der Regler und deren mathematischen Herleitungen im Detail eingegangen. Des Weiteren werden die Implementierungen der Sensorsteuerung, der Anwendungsstruktur und der Diagramme beschrieben

DEVELOPMENT OF PROGRAMMABLE PEPTIDE CONSTRUCTS FOR CONTROLLING THE ASSEMBLY ARCHITECTURE AND PROPERTIES OF GOLD NANOPARTICLE SUPERSTRUCTURES AND SOFT MATERIALS

This dissertation describes advances in the development of peptide-based methods for assembling nanomaterials. The aim of my work is four-fold: 1) develop methods to rationally tune the metrics of gold nanoparticle superstructures; 2) develop approaches to post-synthetically modify and stabilize gold nanoparticle superstructures; 3) develop an understanding of the underlying peptide assembly scaffold and how it dictates the final nanoparticle assembly architecture; and 4) develop new hybrid materials with peptide conjugate molecules having programmable R-groups. Specifically, in Chapter 2 I describe methods to tune the assembly of double-helical gold nanoparticle superstructures by modulating the sterics and hydrophobicity of a family of new peptide conjugate molecules. I show that I can tune the assembly metrics of doubles helices including pitch, nanoparticle size, and interhelical distance. Chapter 3 describes the construction of single-helical gold nanoparticle superstructures that exhibit intense chiroptical activity. I examine their underlying peptide assembly structure and arrive at a molecular-level understanding of their assembly and how it relates to the chiral nanoparticle superstructure. In Chapter 4, I demonstrate a straightforward approach to rationally tune the metrics of hollow spherical gold nanoparticle superstructures including nanoparticle coverage density and sphere diameters. I further demonstrate that their assembly can be stabilized post-synthetically via ligand exchange. Finally, in Chapter 5 I design new peptide conjugate building blocks composed of peptides and oligonucleotides interlinked by a hydrophobic organic core. I outline design rules that govern their assembly and show that their assembly morphology can be rationally predicted and altered

Locust bean gum hydrogels are bioadhesive and improve indole-3-carbinol cutaneous permeation: influence of the polysaccharide concentration

The locust bean gum (LBG) is a polysaccharide with thickening, stabilizing and gelling properties and it has been used in the preparation of pharmaceutical formulations. Hydrogels (HGs) are obtained from natural or synthetic materials that present interesting properties for skin application. This study aimed to develop HGs from LBG using indole-3-carbinol (I3C) as an asset model for cutaneous application. HGs were prepared by dispersing LBG (2%, 3% and 4% w/v) directly in cold water. The formulations showed content close to 0.5 mg/g (HPLC) and pH ranging from 7.25 to 7.41 (potentiometry). The spreadability factor (parallel plate method) was inversely proportional to LBG concentration. The rheological evaluation (rotational viscometer) demonstrated a non-Newtonian pseudoplastic flow behavior (Ostwald De Weale model), which is interesting for cutaneous application. The HET-CAM evaluation showed the non-irritating characteristic of the formulations. The bioadhesive potential demonstrated bioadhesion in a concentration-dependent manner. Permeation in human skin using Franz cells showed that the highest LBG concentration improved the skin distribution profile with greater I3C amounts in the viable skin layers. The present study demonstrated the feasibility of preparing HGs with LBG and the formulation with the highest polymer concentration was the most promising to transport active ingredients through the skin

Avaliação psicológica como fator protetor à interrupção de tratamento na psicoterapia psicanalítica de crianças: dados empíricos

A avaliação psicológica pode fornecer informações importantes sobre sintomas, personalidade, diagnóstico e prognóstico do paciente, auxiliando no desenvolvimento de estratégias terapêuticas. Esta coorte retrospectiva objetivou determinar se há associação entre a realização de avaliação psicológica antes da psicoterapia e a permanência dos pacientes em tratamento. Foram analisados prontuários de 2.106 crianças atendidas em dois ambulatórios de saúde mental em Porto Alegre. Crianças que haviam realizado avaliação psicológica antes de iniciar a psicoterapia apresentavam 65% mais chance de aderir ao tratamento e 44% menos chance de abandoná-lo do que crianças que não haviam realizado avaliação psicológica. A avaliação psicológica auxilia os pais a se engajarem no tratamento de suas crianças, tornando-o menos coercitivo, além de fornecer uma fundamentação mais concreta para o subjetivo processo psicoterapêutico

Hubungan Faktor Predisposisi Dengan Perilaku Aman Pada Tenaga Kerja Di Pt Aneka Adhilogam Karya Desa Batur Kecamatan Ceper Kabupaten Klaten

The number of work accidents in Indonesia reaches 337 million work accidents occur each year resulting in approximately 2.3 million workers lost their lives. Then the application of occupational safety and health must be in accordance with the standards and legislation. It must be applied by all types of companies both formal and informal. The purpose of this study was to determine the relationship between predisposing factors and safe behavior in the workforce at PT Aneka Adhilogam Karya in Batur Village, Ceper District, Klaten Regency. This research method uses quantitative research with cross sectional approach involving 79 respondents taken in total sampling. Predisposing variables in this study are knowledge, age, attitude, education and years of service, as measured by a research questionnaire. Analysis of the data used is univariate and bivariate analysis. The results showed that there was a significant influence between knowledge, age, attitude, education and years of work with safe behavior at PT Aneka Adhilogam Karya in Batur Village, Ceper District, Klaten Regenc

Humor i reklame - Er du overbevist?

Denne bacheloroppgaven ser nærmere på hvilke faktorer som spiller inn på forholdet mellom humor og vareprat. Den går dypere inn på effekter som kommer av humor, da spesielt distraksjonseffekten som en hovedfaktor. Vi ønsket å undersøke om distraksjon, opphisselse (arousal), holdning til reklame og holdning til merkevare fungerer som medierende variabler på forholdet mellom humor og vareprat. Vi kom dermed frem til følgende problemstilling: «I hvilken grad kan humor i reklame, gjennom distraksjonseffekten, bidra til å genere mer positiv vareprat til merkevaren?» Bakgrunnen for oppgaven var å se på hvordan humor påvirker holdning til merkevare gjennom holdning til reklame. Vi fant dette interessant å se i lys av vareprat og i tillegg avdekke om distraksjonseffekten har spilt en rolle. Det teoretiske utgangspunktet for denne oppgaven fokuserer på fem hovedtemaer: holdning, følelser (arousal), vareprat, humor og distraksjonseffekten. For å gjennomføre undersøkelsen har vi valgt å benytte oss av kvantitativ metode i form av et enkelt «post» eksperiment. Dette designet ble valgt for å kunne sammenligne effekter. Det ble gjort under kontrollerte omstendigheter for å sikre at eksperimentet hadde god intern validitet. Vi gjorde også tiltak for å forsterke den eksterne validiteten. Utvalget bestod hovedsakelig av studenter ved Høyskolen Kristiania i Oslo. Vi fikk ikke støtte for noen av våre hypoteser, men fant andre interessante funn. En ting vi ble gjort oppmerksomme på var at humor i vårt eksperiment genererte mer motargumentasjon, som er motsatt av hva vi forventet. Vi fant også at noen av de medierende variablene hadde en sammenheng seg imellom, men at de ikke var generert av humor eller ledet til vareprat. Vi konkluderte med at det kreves mer forskning på fenomenet for å enten avkrefte eller bekrefte tilstedeværelse av mediatorene i forholdet mellom humor og vareprat

Anisotropic behaviour of human gallbladder walls

Inverse estimation of biomechanical parameters of soft tissues from non-invasive measurements has clinical significance in patient-specific modelling and disease diagnosis. In this paper, we propose a fully nonlinear approach to estimate the mechanical properties of the human gallbladder wall muscles from in vivo ultrasound images. The iteration method consists of a forward approach, in which the constitutive equation is based on a modified Hozapfel–Gasser–Ogden law initially developed for arteries. Five constitutive parameters describing the two orthogonal families of fibres and the matrix material are determined by comparing the computed displacements with medical images. The optimisation process is carried out using the MATLAB toolbox, a Python code, and the ABAQUS solver. The proposed method is validated with published artery data and subsequently applied to ten human gallbladder samples. Results show that the human gallbladder wall is anisotropic during the passive refilling phase, and that the peak stress is 1.6 times greater than that calculated using linear mechanics. This discrepancy arises because the wall thickness reduces by 1.6 times during the deformation, which is not predicted by conventional linear elasticity. If the change of wall thickness is accounted for, then the linear model can used to predict the gallbladder stress and its correlation with pain. This work provides further understanding of the nonlinear characteristics of human gallbladder