91 research outputs found

    Refined Topological Vertex, Cylindric Partitions and the U(1) Adjoint Theory

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    We study the partition function of the compactified 5D U(1) gauge theory (in the Omega-background) with a single adjoint hypermultiplet, calculated using the refined topological vertex. We show that this partition function is an example a periodic Schur process and is a refinement of the generating function of cylindric plane partitions. The size of the cylinder is given by the mass of adjoint hypermultiplet and the parameters of the Omega-background. We also show that this partition function can be written as a trace of operators which are generalizations of vertex operators studied by Carlsson and Okounkov. In the last part of the paper we describe a way to obtain (q,t) identities using the refined topological vertex.Comment: 40 Page

    Attention deficit hyperactivity disorder, some considerations about treatment and diagnosis

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    Introducción: el trastorno por déficit de atención afecta a más del 5% de la población infantil a nivel mundial. Objetivo: destacar algunos elementos de su diagnóstico y su tratamiento fue el propósito de la revisión. Métodos: se abarcaron los años comprendidos entre 1999 y 2017. Más del 75% de la bibliografía corresponden a artículos de internet, a revistas digitales disponibles en bases de datos regionales y a guías terapéuticas de asociaciones vinculadas al estudio, el diagnóstico, el tratamiento y la rehabilitación de los pacientes con trastorno por déficit de atención. Desarrollo: para el diagnóstico del trastorno por déficit de atención es importante el uso de la evaluación clínica, la anamnesis, el examen físico y los antecedentes familiares, entre otros, así como el cumplimiento de los criterios del Manual diagnóstico y estadístico de enfermedades mentales (5) y de la Clasificación Internacional de enfermedades (10), todo apoyado por las pruebas psicológicas y neurobiológicas. Conclusiones: en su estudio se emplean disímiles instrumentos, escalas, entrevistas psicológicas y pruebas biológicas que proporcionan su diagnóstico. El tratamiento se ha basado, principalmente, en el uso de estimulantes del sistema nervioso central, aunque se ponen en práctica otras alternativas. El tratamiento multimodal e individualizado garantiza una evolución favorable y evita las complicaciones.Introduction: assistance deficit disorder affects today more than 5% of the child population worldwide. Objective: to highlight some elements of its diagnosis and treatment was the purpose of the review. Methods: the years comprised between 1999 even 2017 were included. More than 75% of the bibliographies correspond to internet articles, digital journals available in regional data bases and therapeutic guidelines of associations linked to the study, diagnose, treatment and rehabilitation of patients with attention deficit disorder. Development: to the diagnosis of attention deficit disorder, it is important the use of clinical evaluation, anamneses, physical examination, family antecedents, among others, as well as correctness with diagnosis and statistics of mental illness (5) Manual criteria and the International Classification of diseases (10), all supported by the psychological and neurobiological tests. Conclusions: in its study, dissimilar instruments, scales, psychological interviews and biological tests are used, which together provide their diagnosis. The treatment has been based, mainly, on the use of the central nervous system stimulants, although other alternatives are put into practice today. The multimodal and individualized treatment in all its aspects guarantees a favorable evolution and avoids complications

    Predicting the Impact of Long-Term Temperature Changes on the Epidemiology and Control of Schistosomiasis: A Mechanistic Model

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    , the causative agent of schistosomiasis in humans.The model showed that the impact of temperature on disease prevalence and abundance is not straightforward; the mean infection burden in humans increases up to 30°C, but then crashes at 35°C, primarily due to increased mortalities of the snail intermediate host. In addition, increased temperatures changed the dynamics of disease from stable, endemic infection to unstable, epidemic cycles at 35°C. However, the prevalence of infection was largely unchanged by increasing temperatures. Temperature increases also affected the response of the model to changes in each parameter, indicating certain control strategies may become less effective with local temperature changes. At lower temperatures, the most effective single control strategy is to target the adult parasites through chemotherapy. However, as temperatures increase, targeting the snail intermediate hosts, for example through molluscicide use, becomes more effective. will not respond to increased temperatures in a linear fashion, and the optimal control strategy is likely to change as temperatures change. It is only through a mechanistic approach, incorporating the combined effects of temperature on all stages of the life-cycle, that we can begin to predict the consequences of climate change on the incidence and severity of such diseases

    NCAM (CD56) Expression in keratin-producing odontogenic cysts: aberrant expression in KCOT

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    Background: Keratin-producing odontogenic cysts (KPOCs) are a group of cystic lesions that are often aggressive, with high rates of recurrence and multifocality. KPOCs included orthokeratinised odontogenic cyst (OOC) and parakeratotic odontogenic cysts, which are now considered true tumours denominated keratocystic odontogenic tumours (KCOTs). GLUT1 is a protein transporter that is involved in the active uptake of glucose across cell membranes and that is overexpressed in tumours in close correlation with the proliferation rate and positron emission tomography (PET) imaging results. Methods: A series of 58 keratin-producing odontogenic cysts was evaluated histologically and immunohistochemically in terms of GLUT1 expression. Different data were correlated using the beta regression model in relation to histological type and immunohistochemical expression of GLUT1, which was quantified using two different morphological methods. Results: KPOC cases comprised 12 OOCs and 46 KCOTs, the latter corresponding to 6 syndromic and 40 sporadic KCOTs. GLUT1 expression was very low in OOC cases compared with KCOT cases, with statistical significant differences when quantification was considered. Different GLUT1 localisation patterns were revealed by immunostaining, with the parabasal cells showing higher reactivity in KCOTs. However, among KCOTs cases, GLUT1 expression was unable to establish differences between syndromic and sporadic cases. Conclusions: GLUT1 expression differentiated between OOC and KCOT cases, with significantly higher expression in KCOTs, but did not differentiate between syndromic and sporadic KCOT cases. However, given the structural characteristics of KCOTs, we hypothesised that PET imaging methodology is probably not a useful diagnostic tool for KCOTs. Further studies of GLUT1 expression and PET examination in KCOT series are needed to confirm this last hypothesis. Keywords: Glucose transporter protein, Immunohistochemistry, Keratin-producing odontogenic cyst, Keratocystic odontogenic tumour, Orthokeratinised odontogenic cyst, Positron emission tomograph

    Variability in childhood allergy and asthma across ethnicity, language, and residency duration in El Paso, Texas: a cross-sectional study

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    <p>Abstract</p> <p>Background</p> <p>We evaluated the impact of migration to the USA-Mexico border city of El Paso, Texas (USA), parental language preference, and Hispanic ethnicity on childhood asthma to differentiate between its social and environmental determinants.</p> <p>Methods</p> <p>Allergy and asthma prevalence was surveyed among 9797 fourth and fifth grade children enrolled in the El Paso Independent School District. Parents completed a respiratory health questionnaire, in either English or Spanish, and a sub-sample of children received spirometry testing at their school. Here we report asthma and allergy outcomes across ethnicity and El Paso residency duration.</p> <p>Results</p> <p>Asthma and allergy prevalence increased with longer duration of El Paso residency independent of ethnicity and preferred language. Compared with immigrants who arrived in El Paso after entering first grade (18%), lifelong El Paso residents (68%) had more prevalent allergy (OR, 1.72; 95% CI, 1.32 - 2.24), prevalent asthma (OR, 1.75; 95% CI, 1.24 - 2.46), and current asthma (OR, 2.01; 95% CI, 1.37 - 2.95). Spirometric measurements (FEV<sub>1</sub>/FVC and FEF<sub>25-75</sub>) also declined with increasing duration of El Paso residency (0.16% and 0.35% annual reduction, respectively).</p> <p>Conclusion</p> <p>These findings suggest that a community-wide environmental exposure in El Paso, delayed pulmonary development, or increased health of immigrants may be associated with allergy and asthma development in children raised there.</p

    The princess and the goblin

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