261 research outputs found
Meeting your match: How attractiveness similarity affects approach behavior in mixed-sex dyads
Item does not contain fulltextThis experimental study investigated approach behavior toward opposite-sex others of similar versus dissimilar physical attractiveness. Furthermore, it tested the moderating effects of sex. Single participants interacted with confederates of high and low attractiveness. Observers rated their behavior in terms of relational investment (i.e., behavioral efforts related to the improvement of interaction fluency, communication of positive interpersonal affect, and positive self-presentation). As expected, men displayed more relational investment behavior if their own physical attractiveness was similar to that of the confederate. For women, no effects of attractiveness similarity on relational investment behavior were found. Results are discussed in the light of positive assortative mating, preferences for physically attractive mates, and sex differences in attraction-related interpersonal behaviors.13 p
PENYALAHGUNAAN ASET NEGARA DALAM BENTUK JARINGAN SATELIT UNTUK KEPENTINGAN KORPORASI DIHUBUNGKAN DENGAN UNDANGUNDANG NOMOR 36 TAHUN 1999 TENTANG TELEKOMUNIKASI JO UNDANGUNDANG NOMOR 20 TAHUN 2001 TENTANG TINDAK PIDANA KORUPSI
telekomunikasi sebagaimana dilakukan oleh IM2. IM2 telah menyalahgunakan pita
frekuensi 2.1 Ghz, dan secara melawan hukum beroperasi pada jaringan tersebut sehingga
menimbulkan kerugian negara. Berdasarkan hal tersebut maka penulis tertarik meneliti,
bagaimana Undang-Undang Telekomunikasi jo Peraturan Menteri Komunikasi dan
Informatika dan Undang-Undang Tindak Pidana Korupsi mengatur mekanisme pemanfaatan
aset negara berupa jaringan satelit, mengapa aset negara berupa jaringan satelit kerap kali
disalahgunakan didalam pemanfaatannya oleh korporasi, serta bagaimana upaya yang dapat
dilakukan untuk melindungi aset negara dalam bentuk jaringan satelit terhadap
penyalahgunaan yang dilakukan oleh korporasi.
Penelitian ini menggunakan spesifikasi penelitian yang bersifat deskriftif analitis
dengan pendekatan yuridis normatif dibantu yuridis empiris, data yang diperlukan dalam
penelitian ini dikumpulkan melalui studi kepustakaan dan studi lapangan, kemudian
dianalisis menggunakan teknik analisis data berupa yuridis kualitatif.
Pemanfaatan aset negara berupa jaringan satelit melalui pita frekuensi merupakan
salah satu hak yang dalam pemanfaatannya diatur oleh peraturan perundang-undangan agar
tercipta keadilan, kepastian dan ketertiban, keamanan, keseimbangan, perlindungan dan
pemeliharaan dalam pemanfataannya. Jaringan satelit yang merupakan jaringan satelit aset
negara pemanfaatannya mensyaratkan izin dan pembayaran tarif tertentu, sehingga
konsekuensinya ketika terjadi penyalahgunaan pemanfaatan jaringan satelit, negara akan
mengalami kerugian. Aset negara berupa jaringan satelit kerap kali disalahgunakan didalam
pemanfaatannya oleh korporasi disebabkan beberapa faktor diantaranya faktor hukum itu
sendiri dalam hal ini peraturan perundang-undangannya, faktor penegak hukum, faktor sarana
atau fasilitas yang mendukung pengawasan dan penegakan hukum itu sendiri, faktor
masyarakat, yakni lingkungan dimana hukum tersebut berlaku atau diterapkan, dalam hal ini
yaitu lingkungan korporasi, faktor kebudayaan yakni kurangnya kesadaran hukum korporasi
dalam upaya pemanfaatan aset negara secara berkeadilan dan tertib sesuai peraturan
perundang-undangan yang berlaku, dimana pemanfaatan yang tidak secara berkeadilan akan
membawa negara menuju kepada kehancuran. Upaya yang dapat dilakukan untuk melindungi
aset negara dalam bentuk jaringan satelit terhadap penyalahgunaan yang dilakukan oleh
korporasi harus berangkat dari beberapa faktor yang menjadi penyebab penyalahgunaan
pemanfaatan jaringan satelit diantaranya yaitu melalui upaya preventif berupa revisi
perunang-undangan, pengawasan, sosialisasi sert upaya represif berupa penegakan hukum.
Penegakan hukum harus dilaksanakan tanpa pandang bulu, sebagai bentuk keyakinan atas
doktrin hukum, bahwa setiap orang mempunyai kedudukan yang sama di depan hukum.
Kata Kunci: Penyalahgunaan Aset Negara, Jaringan Sateli
Quality of life of children with hearing loss in special and mainstream education: a longitudinal study
Objectives: To compare the quality of life (QoL) of children with hearing loss (HL) and children with normal hearing (NH) and to examine how the QoL of children with HL changes over time, considering language skills, type of hearing device, degree of HL, and type of education.Methods and materials: This longitudinal study included 62 children with HL and their parents. Developmental outcome data were collected at two time points, when the mean ages of the children were 4 and 11 years. The Pediatric Quality of Life (PedsQL (TM)) questionnaire, which includes assessments of Physical, Emotional, Social, and School functioning, was completed by parents at both time points and by the children with HL at the second time point. Receptive and expressive language skills at 4 years were assessed by the Reynell Developmental Language Scale. Results were compared with a Dutch normative sample.Results: The QoL of children with HL was similar to that of children with NH at both time points on two of the four QoL scales, Emotional and Physical functioning. On the other two scales, Social and School functioning, children with HL who attended special education and children who switched to mainstream education showed lower scores than children with HL who were consistently in mainstream education and lower scores than children with NH. The School QoL of children with HL decreased over time, as did the School QoL of children with NH. Social QoL of children with cochlear implants decreased over time, but this was not the case in children with hearing aids. Language skills and the degree of HL did not clinically improve the QoL over time of preschool children with HL.Conclusions: The QoL of children with HL in mainstream education and the Physical and Emotional QoL of all children with HL were satisfactory. It is essential to develop specific guidance regarding school activities for children with HL in special education and for children with HL who switch to mainstream education in order to increase their social QoL.Pathways through Adolescenc
Sorting Based on Urban Heritage and Income: Evidence from the Amsterdam Metropolitan Area
Feasibility of pharmacy-initiated pharmacogenetic screening for CYP2D6 and CYP2C19
PURPOSE: Our purpose was to investigate the feasibility of pharmacy-initiated pharmacogenetic (PGt) screening in primary care with respect to patient willingness to participate, quality of DNA collection with saliva kits, genotyping, and dispensing data retrieved from the pharmacy. METHODS: Polypharmacy patients aged >60 years who used at least one drug with Anatomical Therapeutic Chemical (ATC) code N06AA01-N06AX19 (antidepressants), A02BC01-A02BC05 (proton-pump inhibitors), N05AA01-N05AH04 (antipsychotics), or C07AB02 (metoprolol) in the preceding 2 years were randomly selected. DNA was collected with saliva kits and genotyped for CYP2D6 and CYP2C19 with the AmpliChip. Pharmacy dispensing records were retrieved and screened for drugs interacting with the patient's CYP2D6 and CYP2C19 genotype by using the evidence-based PGt guidelines from the Dutch Pharmacogenetics Working Group. RESULTS: Out of the 93 invited patients, 54 (58.1%) provided informed consent. Nine saliva samples (16.7%) contained too little DNA. Call rates for CYP2D6 and CYP2C19 were 93.3% and 100%, respectively. Frequencies of genotype-predicted phenotype were 2.4%, 38.1%, 54.8%, and 4.8% for CYP2D6 poor metabolizers (PM), intermediate metabolizers (IM), extensive metabolizers (EM), and ultrarapid metabolizers (UM) respectively. For CYP2C19 genotype-predicted phenotype, frequencies were 2.2%, 15.6%, and 82.2% for PM, IM, and EM, respectively. CONCLUSIONS: This study shows that pharmacy-initiated PGt screening is feasible for a primary care setting
Structure of the stationary phase survival protein YuiC from B.subtilis
- Background: Stationary phase survival proteins (Sps) were found in Firmicutes as having
analogous domain compositions, and in some cases genome context, as the resuscitation
promoting factors of Actinobacteria, but with a different putative peptidoglycan cleaving
domain.
- Results: The first structure of a Firmicute Sps protein YuiC from B. subtilis, is found to be a
stripped down version of the cell-wall peptidoglycan hydrolase MltA. The YuiC structures are of
a domain swapped dimer, although some monomer is also found in solution. The protein
crystallised in the presence of pentasaccharide shows a 1,6-anhydrodisaccharide sugar product,
indicating that YuiC cleaves the sugar backbone to form an anhydro product at least on lengthy
incubation during crystallisation.
- Conclusions:
The structural simplification of MltA in Sps proteins is analogous to that of the resuscitation
promoting factor domains of Actinobacteria, which are stripped down versions of lysozyme and
soluble lytic transglycosylase proteins
Can current moisture responses predict soil CO2 efflux under altered precipitation regimes? A synthesis of manipulation experiments.
As a key component of the carbon cycle, soil CO2 efflux (SCE) is being increasingly studied to improve our mechanistic understanding of this important carbon flux. Predicting ecosystem responses to climate change often depends on extrapolation of current relationships between ecosystem processes and their climatic drivers to conditions not yet experienced by the ecosystem. This raises the question of to what extent these relationships remain unaltered beyond the current climatic window for which observations are available to constrain the relationships. Here, we evaluate whether current responses of SCE to fluctuations in soil temperature and soil water content can be used to predict SCE under altered rainfall patterns. Of the 58 experiments for which we gathered SCE data, 20 were discarded because either too few data were available or inconsistencies precluded their incorporation in the analyses. The 38 remaining experiments were used to test the hypothesis that a model parameterized with data from the control plots (using soil temperature and water content as predictor variables) could adequately predict SCE measured in the manipulated treatment. Only for 7 of these 38 experiments was this hypothesis rejected. Importantly, these were the experiments with the most reliable data sets, i.e., those providing high-frequency measurements of SCE. Regression tree analysis demonstrated that our hypothesis could be rejected only for experiments with measurement intervals of less than 11 days, and was not rejected for any of the 24 experiments with larger measurement intervals. This highlights the importance of high-frequency measurements when studying effects of altered precipitation on SCE, probably because infrequent measurement schemes have insufficient capacity to detect shifts in the climate dependencies of SCE. Hence, the most justified answer to the question of whether current moisture responses of SCE can be extrapolated to predict SCE under altered precipitation regimes is ?no? ? as based on the most reliable data sets available. We strongly recommend that future experiments focus more strongly on establishing response functions across a broader range of precipitation regimes and soil moisture conditions. Such experiments should make accurate measurements of water availability, should conduct high-frequency SCE measurements, and should consider both instantaneous responses and the potential legacy effects of climate extremes. This is important, because with the novel approach presented here, we demonstrated that, at least for some ecosystems, current moisture responses could not be extrapolated to predict SCE under altered rainfall conditions
Sex differences in short-term mate preferences and behavioral mimicry: A semi-naturalistic experiment
Item does not contain fulltextStudies on short-term mating (STM) yield sex differences regarding preferences for attractiveness (important towomen, very important to men) and social status (very important to women, not to men) in potential mates. Additionally, men generally report a greater desire to engage in STM than women. So far, this evidence is primarily based on studies using vignettes or surveys. The current study extended the findings on sex differences in STM by examining actual behavior and STM-desires towards real people of the opposite sex. It investigated whether (1) sex differences exist in STM-desire, (2) whether this desire was affected by a confederate's attractiveness and status, and (3) if these sex differences were also reflected in interpersonal behavior (mimicry). In a pub-like laboratory, single heterosexual participants performed a task alongside a confederate of the
opposite sex, who differed in attractiveness and social status. Mimicry was observed and explicit STM-desire was assessed. Results showed that men only desired STM more than women in the case of an attractive partner. Women's STMdesire did not vary as a function of status or ttractiveness of the potential partner. Men’s, but not women's, mimicry paralleled these differential STM-desires. These results underline the conditionality of sex differences in STM-desire and provide a useful paradigm to further investigate STM.10 p
Can current moisture responses predict soil CO2 efflux under altered precipitation regimes? A synthesis of manipulation experiments
As a key component of the carbon cycle, soil CO2 efflux (SCE) is being increasingly studied to improve our mechanistic understanding of this important carbon flux. Predicting ecosystem responses to climate change often depends on extrapolation of current relationships between ecosystem processes and their climatic drivers to conditions not yet experienced by the ecosystem. This raises the question of to what extent these relationships remain unaltered beyond the current climatic window for which observations are available to constrain the relationships. Here, we evaluate whether current responses of SCE to fluctuations in soil temperature and soil water content can be used to predict SCE under altered rainfall patterns. Of the 58 experiments for which we gathered SCE data, 20 were discarded because either too few data were available or inconsistencies precluded their incorporation in the analyses. The 38 remaining experiments were used to test the hypothesis that a model parameterized with data from the control plots (using soil temperature and water content as predictor variables) could adequately predict SCE measured in the manipulated treatment. Only for 7 of these 38 experiments was this hypothesis rejected. Importantly, these were the experiments with the most reliable data sets, i.e., those providing high-frequency measurements of SCE. Regression tree analysis demonstrated that our hypothesis could be rejected only for experiments with measurement intervals of less than 11 days, and was not rejected for any of the 24 experiments with larger measurement intervals. This highlights the importance of high-frequency measurements when studying effects of altered precipitation on SCE, probably because infrequent measurement schemes have insufficient capacity to detect shifts in the climate dependencies of SCE. Hence, the most justified answer to the question of whether current moisture responses of SCE can be extrapolated to predict SCE under altered precipitation regimes is 'no' - as based on the most reliable data sets available. We strongly recommend that future experiments focus more strongly on establishing response functions across a broader range of precipitation regimes and soil moisture conditions. Such experiments should make accurate measurements of water availability, should conduct high-frequency SCE measurements, and should consider both instantaneous responses and the potential legacy effects of climate extremes. This is important, because with the novel approach presented here, we demonstrated that, at least for some ecosystems, current moisture responses could not be extrapolated to predict SCE under altered rainfall conditions
High-fidelity operation and algorithmic initialisation of spin qubits above one kelvin
The encoding of qubits in semiconductor spin carriers has been recognised as
a promising approach to a commercial quantum computer that can be
lithographically produced and integrated at scale. However, the operation of
the large number of qubits required for advantageous quantum applications will
produce a thermal load exceeding the available cooling power of cryostats at
millikelvin temperatures. As the scale-up accelerates, it becomes imperative to
establish fault-tolerant operation above 1 kelvin, where the cooling power is
orders of magnitude higher. Here, we tune up and operate spin qubits in silicon
above 1 kelvin, with fidelities in the range required for fault-tolerant
operation at such temperatures. We design an algorithmic initialisation
protocol to prepare a pure two-qubit state even when the thermal energy is
substantially above the qubit energies, and incorporate high-fidelity
radio-frequency readout to achieve an initialisation fidelity of 99.34 per
cent. Importantly, we demonstrate a single-qubit Clifford gate fidelity of
99.85 per cent, and a two-qubit gate fidelity of 98.92 per cent. These advances
overcome the fundamental limitation that the thermal energy must be well below
the qubit energies for high-fidelity operation to be possible, surmounting a
major obstacle in the pathway to scalable and fault-tolerant quantum
computation
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