1,375 research outputs found
Investigating plywood behaviour in outdoor conditions
Moisture behaviour of plywood is investigated in combination with detailed structural analysis. In the lab, neutron radiography and X-ray computed tomography (X-ray CT) were used to map the moisture distribution and internal structure of plywood respectively. In an outdoor natural weathering test, the average moisture content (MC) and moisture distribution of plywood were monitored using a continuous moisture measurement set-up and an adapted electrical method, respectively. The structural changes of the specimens during weathering were recorded by using X-ray CT. Based on the interrelationship of moisture behaviour and structure, suggestions are given for improving the water resistance of plywood by optimising structure
Molecular technologies in the marine environment: assessing the status of marine ecosystems with just four letters ACTG
Automated PGP9.5 immunofluorescence staining: a valuable tool in the assessment of small fiber neuropathy?
BACKGROUND: In this study we explored the possibility of automating the PGP9.5 immunofluorescence staining assay for the diagnosis of small fiber neuropathy using skin punch biopsies. The laboratory developed test (LDT) was subjected to a validation strategy as required by good laboratory practice guidelines and compared to the well-established gold standard method approved by the European Federation of Neurological Societies (EFNS). To facilitate automation, the use of thinner sections. (16 µm) was evaluated. Biopsies from previously published studies were used. The aim was to evaluate the diagnostic performance of the LDT compared to the gold standard. We focused on technical aspects to reach high-quality standardization of the PGP9.5 assay and finally evaluate its potential for use in large scale batch testing. RESULTS: We first studied linear nerve fiber densities in skin of healthy volunteers to establish reference ranges, and compared our LDT using the modifications to the EFNS counting rule to the gold standard in visualizing and quantifying the epidermal nerve fiber network. As the LDT requires the use of 16 µm tissue sections, a higher incidence of intra-epidermal nerve fiber fragments and a lower incidence of secondary branches were detected. Nevertheless, the LDT showed excellent concordance with the gold standard method. Next, the diagnostic performance and yield of the LDT were explored and challenged to the gold standard using skin punch biopsies of capsaicin treated subjects, and patients with diabetic polyneuropathy. The LDT reached good agreement with the gold standard in identifying small fiber neuropathy. The reduction of section thickness from 50 to 16 µm resulted in a significantly lower visualization of the three-dimensional epidermal nerve fiber network, as expected. However, the diagnostic performance of the LDT was adequate as characterized by a sensitivity and specificity of 80 and 64 %, respectively. CONCLUSIONS: This study, designed as a proof of principle, indicated that the LDT is an accurate, robust and automated assay, which adequately and reliably identifies patients presenting with small fiber neuropathy, and therefore has potential for use in large scale clinical studies
Angular diameters, fluxes and extinction of compact planetary nebulae: further evidence for steeper extinction towards the Bulge
We present values for angular diameter, flux and extinction for 70 Galactic
planetary nebulae observed using narrow band filters. Angular diameters are
derived using constant emissivity shell and photoionization line emission
models. The mean of the results from these two models are presented as our best
estimate. Contour plots of 36 fully resolved objects are included and the low
intensity contours often reveal an elliptical structure that is not always
apparent from FWHM measurements. Flux densities are determined, and for both
H-alpha and O[III] there is little evidence of any systematic differences
between observed and catalogued values. Observed H-alpha extinction values are
determined using observed H-alpha and catalogued radio fluxes. H-alpha
extinction values are also derived from catalogued H-alpha and H-beta flux
values by means of an Rv dependent extinction law. Rv is then calculated in
terms of observed extinction values and catalogued H-alpha and H-beta flux
values. Comparing observed and catalogue extinction values for a subset of
Bulge objects, observed values tend to be lower than catalogue values
calculated with Rv = 3.1. For the same subset we calculate = 2.0,
confirming that toward the Bulge interstellar extinction is steeper than Rv =
3.1. For the inner Galaxy a relation with the higher supernova rate is
suggested, and that the low-density warm ionized medium is the site of the
anomalous extinction. Lowvalues of extinction are also derived using dust
models with a turnover radius of 0.08 microns.Comment: Accepted by MNRAS. 17 pages, 9 figures (including 36 contour plots of
PNe), 5 Tables (including 2 large tables of angular diameters, fluxes and
extinction
Relationship between spatial proximity and travel-to-work distance : the effect of the compact city
In this paper, an assessment is made of the relationship between selected aspects of spatial proximity (density, diversity, minimum commuting distance, jobs-housing balance and job accessibility) and reported commuting distances in Flanders (Belgium). Results show that correlations may depend on the considered trip end. For example, a high residential density, a high degree of spatial diversity and a high level of job accessibility are all associated with a short commute by residents, while a high job density is associated with a long commute by employees. A jobs-housing balance close to one is associated with a short commute, both by residents and by employees. In general, it appears that the alleged sustainability benefits of the compact city model are still valid in a context of continuously expanding commuting trip lengths
Trigonometric Parallaxes of Central Stars of Planetary Nebulae
Trigonometric parallaxes of 16 nearby planetary nebulae are presented,
including reduced errors for seven objects with previous initial results and
results for six new objects. The median error in the parallax is 0.42 mas, and
twelve nebulae have parallax errors less than 20 percent. The parallax for
PHL932 is found here to be smaller than was measured by Hipparcos, and this
peculiar object is discussed. Comparisons are made with other distance
estimates. The distances determined from these parallaxes tend to be
intermediate between some short distance estimates and other long estimates;
they are somewhat smaller than estimated from spectra of the central stars.
Proper motions and tangential velocities are presented. No astrometric
perturbations from unresolved close companions are detected.Comment: 24 pages, includes 4 figures. Accepted for A
The active living gender's gap challenge: 2013-2017 Eurobarometers physical inactivity data show constant higher prevalence in women with no progress towards global reduction goals
BACKGROUND: The World Health Organization (WHO) considers physical inactivity (PIA) as a critical noncommunicable factor for disease and mortality, affecting more women than men. In 2013, the WHO set a 10% reduction of the PIA prevalence, with the goal to be reached by 2025. Changes in the 2013-2017 period of physical inactivity prevalence in the 28 European Union (EU) countries were evaluated to track the progress in achieving WHO 2025 target. METHODS: In 2013 and 2017 EU Special Eurobarometers, the physical activity levels reported by the International Physical Activity Questionnaire of 53,607 adults were analyzed. Data were considered as a whole sample and country-by-country. A χ2 test was used to analyze the physical inactivity prevalence (%) between countries, analyzing women and men together and separately. Additionally, PIA prevalence was analyzed between years (2013-2017) for the overall EU sample and within-country using a Z-Score for two population proportions. RESULTS: The PIA prevalence increased between 2013 and 2017 for the overall EU sample (p < 0.001), and for women (p = 0.04) and men (p < 0.001) separately. Data showed a higher PIA prevalence in women versus men during both years (p < 0.001). When separately considering changes in PIA by gender, only Belgium's women and Luxembourg's men showed a reduction in PIA prevalence. Increases in PIA prevalence over time were observed in women from Austria, Croatia, Germany, Lithuania, Malta, Portugal, Romania, and Slovakia and in men from Bulgaria, Croatia, Czechia, Germany, Italy, Lithuania, Portugal, Romania, Slovakia, and Spain. CONCLUSIONS: PIA prevalence showed an overall increase across the EU and for both women and men between 2013 and 2017, with higher rates of PIA reported for women versus men during both years. PIA prevalence was reduced in only Belgium's women and Luxembourg's men. Our data indicate a limited gender-sensible approach while tacking PIA prevalence with no progress reaching global voluntary reductions of PIA for 2025
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