Aspects de la culture d’un vêtu, l’épeautre

1. Une céréale oubliée L’épeautre (Triticum spelta) est une céréale biologiquement très voisine du froment (Triticum aestivum), le blé tendre moderne qui domine largement aujourd’hui dans l’alimentation humaine des pays tempérés. L’épeautre est né par hybridation spontanée entre un blé cultivé, l’amidonnier (Triticum dicoccum) et une adventice commune des champs de blé de Transcaucasie et du Moyen Orient Aegilops squarrosa.  L’épeautre comme le blé tendre sont donc nés au sein de champs culti..

Sediment source fingerprinting: benchmarking recent outputs, remaining challenges and emerging themes

Abstract: Purpose: This review of sediment source fingerprinting assesses the current state-of-the-art, remaining challenges and emerging themes. It combines inputs from international scientists either with track records in the approach or with expertise relevant to progressing the science. Methods: Web of Science and Google Scholar were used to review published papers spanning the period 2013–2019, inclusive, to confirm publication trends in quantities of papers by study area country and the types of tracers used. The most recent (2018–2019, inclusive) papers were also benchmarked using a methodological decision-tree published in 2017. Scope: Areas requiring further research and international consensus on methodological detail are reviewed, and these comprise spatial variability in tracers and corresponding sampling implications for end-members, temporal variability in tracers and sampling implications for end-members and target sediment, tracer conservation and knowledge-based pre-selection, the physico-chemical basis for source discrimination and dissemination of fingerprinting results to stakeholders. Emerging themes are also discussed: novel tracers, concentration-dependence for biomarkers, combining sediment fingerprinting and age-dating, applications to sediment-bound pollutants, incorporation of supportive spatial information to augment discrimination and modelling, aeolian sediment source fingerprinting, integration with process-based models and development of open-access software tools for data processing. Conclusions: The popularity of sediment source fingerprinting continues on an upward trend globally, but with this growth comes issues surrounding lack of standardisation and procedural diversity. Nonetheless, the last 2 years have also evidenced growing uptake of critical requirements for robust applications and this review is intended to signpost investigators, both old and new, towards these benchmarks and remaining research challenges for, and emerging options for different applications of, the fingerprinting approach

Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. Protective HLA-DRB1*04 subtypes strongly bound the aggregation-prone tau PHF6 sequence, however only when acetylated at a lysine (K311), a common posttranslational modification central to tau aggregation. An HLA-DRB1*04-mediated adaptive immune response decreases PD and AD risks, potentially by acting against tau, offering the possibility of therapeutic avenues

Etude morphologique et phylogénétique du ganglion cérébroïde des gastéropodes pulmonés (mollusques)

Doctorat en Sciencesinfo:eu-repo/semantics/nonPublishe

Etude morphologique et phylogénétique du ganglion cérébroïde des gastéropodes pulmonés (mollusques)

Doctorat en Sciencesinfo:eu-repo/semantics/nonPublishe

Le Contexte de l'après-guerre: Le monde rural face au changement

info:eu-repo/semantics/publishe

Note au sujet de Conus magellanicus Hwass in Brugui\ue8re

Volume: 467Start Page: 725End Page: 72

Les Fonderies du Lion (EFEL), les dernières fonderies du Couvinois

info:eu-repo/semantics/publishe

Fonderies de fer & Poêleries

info:eu-repo/semantics/publishe

Innovations techniques en agriculture en Belgique aux XIXe et XXe siècles: Alfred Mélotte, inventeur de charrues, fondateur d’industrie

info:eu-repo/semantics/publishe