Optimizing grinding mill performance using extremum seeking control

A semi-autogenous grinding mill is simulated with an extremum seeking controller to maximize the performance of the mill using grind curves. Grind curves map the essential performance measures of a grinding mill to the manipulable variables. The curves vary with the changes in the feed ore characteristic but show generic parabolic features with extremums. The extremum seeking controller searches along the unknown input-output map using periodic perturbations to steer the process towards an unknown optimum. In this study the controller searches along the grind curves to either optimize the mill throughput or grind by means of the mill feed or rotational speed. The proposed controller will reduce the need for a plant operator to select the optimal operating region. Since the controller is agnostic to the process model, it will also eliminate the tedious process of developing an accurate plant model for model-based control.The National Research Foundation of South Africahttps://www.journals.elsevier.com/ifac-papersonlineam2022Electrical, Electronic and Computer Engineerin

Extremum seeking control for optimization of an open-loop grinding mill using grind curves

A semi-autogenous grinding mill is simulated with gradient and non-gradient based extremum seeking controllers to maximize the mill performance using grind curves. Grind curves map the essential performance measures of a grinding mill to the mill load and rotational speed. The curves vary with the changes in the feed ore characteristic but show generic parabolic features with extremums. The extremum seeking controllers search along the unknown input–output map to steer the process towards an unknown optimum. In this study, a classical perturbation-based method, a time-varying parameter estimation-based method and the Nelder–Mead simplex method are employed as extremum seeking control (ESC) methods to search along the grind curves to either optimize the mill throughput or grind by means of manipulating the mill feed or rotational speed. The proposed extremum seeking controller could reduce the need for a plant operator to manually select the optimal operating conditions that maximize the performance measures of a grinding mill. Since the controller is agnostic to the process model, the grinding mill can be optimized without the need for a detailed process model. The simulated results show that the extremum seeking controllers steer the mill operating conditions toward the steady-state optimum and can be used to satisfy operational objectives. However, the slow grinding mill dynamics result in a long convergence rate when the initial conditions are far from the optimal operating conditions.The National Research Foundation of South Africa.http://www.elsevier.com/locate/jproconthj2022Electrical, Electronic and Computer Engineerin

Remote sensing of vegetation fires and its contribution to a fire management information system

In the last decade, research has proven that remote sensing can provide very useful support to fire managers. This chapter provides an overview of the type of information remote sensing can provide to the fire community. It considers first fire management information needs in the context of fire management information system. An introduction to remote sensing then precedes the description of fire information obtainable from remote sensing data (such as vegetation status, active fire detection and burned areas assessment). Finally, operational examples in five African countries illustrate how the information can be used in practice

8. Remote Sensing Of Vegetation Fires And Its Contribution To A Fire Management Information System

In the last decade, research has proven that remote sensing can provide very useful support to fire managers. This chapter provides an overview of the types of information remote sensing can provide to the fire community. First, it considers fire management information needs in the context of a fire management information system. An introduction to remote sensing then precedes a description of fire information obtainable from remote sensing data (such as vegetation status, active fire detection and burned areas assessment). Finally, operational examples in five African countries illustrate the practical use of remotely sensed fire information. As indicated in previous chapters, fire management usually comprises activities designed to control the frequency, area, intensity or impact of fire. These activities are undertaken in different institutional, economic, social, environmental and geographical contexts, as well as at different scales, from local to national. The range of fire management activities also varies considerably according to the management issues at stake, as well as the available means and capacity to act. Whatever the level, effective fire management requires reliable information upon which to base appropriate decisions and actions. Information will be required at many different stages of this fire management system. To illustrate this, we consider a typical and generic description of a fire management loop , as provided in Figure 8.1. Fire management objectives result from fire related knowledge . For example, they may relate to sound ecological reasons for prescribed burning in a particular land management context, or to frequent, uncontrolled fires threatening valuable natural or human resources. Whatever the issues, appropriate objectives require scientific knowledge (such as fire impact on ecosystems components, such as soil and vegetation), as well as up-to date monitoring information (such as vegetation status, fire locations, land use, socioeconomic context, etc.). Policies, generally at a national and governmental level, provide the official or legal long term framework (e.g. five to ten years) to undertake actions. A proper documentation of different fire issues, and their evolution, will allow their integration into appropriate policies, whether specific to fire management, or complementary to other policies in areas such as forestry, rangeland, biodiversity, land tenure, etc. Strategies are found at all levels of fire management. They provide a shorter-term framework (e.g. one to five years) to prioritise fire management activities. They involve the development of a clear set of objectives and a clear set of activities to achieve these objectives. They may also include research and training inputs required, in order to build capacity and to answer specific questions needed to improve fire management. The chosen strategy will result from a trade-off between priority fire management objectives and the available capacity to act (e.g. institutional framework, budget, staff, etc.), and will lead towards a better allocation of resources for fire management operations to achieve specific objectives. One example in achieving an objective of conserving biotic diversity may be the implementation of a patch-mosaic burning system (Brockett et al., 200 1 ) instead of a prescribed block burning system, based on an assumption that the former should better promote biodiversity in the long-term than the latter (Parr & Brockett, 1999). This strategy requires the implementation of early season fires to reduce the size of later season fires. The knowledge of population movements, new settlements or a coming El Nino season, should help focus the resources usage, as these factors might influence the proportion as well as the locations of area burned. Another strategy may be to prioritise the grading of fire lines earlier than usual based on information on high biomass accumulation. However, whatever the strategies, they need to be based on reliable information

8. Remote Sensing Of Vegetation Fires And Its Contribution To A Fire Management Information System

In the last decade, research has proven that remote sensing can provide very useful support to fire managers. This chapter provides an overview of the types of information remote sensing can provide to the fire community. First, it considers fire management information needs in the context of a fire management information system. An introduction to remote sensing then precedes a description of fire information obtainable from remote sensing data (such as vegetation status, active fire detection and burned areas assessment). Finally, operational examples in five African countries illustrate the practical use of remotely sensed fire information. As indicated in previous chapters, fire management usually comprises activities designed to control the frequency, area, intensity or impact of fire. These activities are undertaken in different institutional, economic, social, environmental and geographical contexts, as well as at different scales, from local to national. The range of fire management activities also varies considerably according to the management issues at stake, as well as the available means and capacity to act. Whatever the level, effective fire management requires reliable information upon which to base appropriate decisions and actions. Information will be required at many different stages of this fire management system. To illustrate this, we consider a typical and generic description of a fire management loop , as provided in Figure 8.1. Fire management objectives result from fire related knowledge . For example, they may relate to sound ecological reasons for prescribed burning in a particular land management context, or to frequent, uncontrolled fires threatening valuable natural or human resources. Whatever the issues, appropriate objectives require scientific knowledge (such as fire impact on ecosystems components, such as soil and vegetation), as well as up-to date monitoring information (such as vegetation status, fire locations, land use, socioeconomic context, etc.). Policies, generally at a national and governmental level, provide the official or legal long term framework (e.g. five to ten years) to undertake actions. A proper documentation of different fire issues, and their evolution, will allow their integration into appropriate policies, whether specific to fire management, or complementary to other policies in areas such as forestry, rangeland, biodiversity, land tenure, etc. Strategies are found at all levels of fire management. They provide a shorter-term framework (e.g. one to five years) to prioritise fire management activities. They involve the development of a clear set of objectives and a clear set of activities to achieve these objectives. They may also include research and training inputs required, in order to build capacity and to answer specific questions needed to improve fire management. The chosen strategy will result from a trade-off between priority fire management objectives and the available capacity to act (e.g. institutional framework, budget, staff, etc.), and will lead towards a better allocation of resources for fire management operations to achieve specific objectives. One example in achieving an objective of conserving biotic diversity may be the implementation of a patch-mosaic burning system (Brockett et al., 200 1 ) instead of a prescribed block burning system, based on an assumption that the former should better promote biodiversity in the long-term than the latter (Parr & Brockett, 1999). This strategy requires the implementation of early season fires to reduce the size of later season fires. The knowledge of population movements, new settlements or a coming El Nino season, should help focus the resources usage, as these factors might influence the proportion as well as the locations of area burned. Another strategy may be to prioritise the grading of fire lines earlier than usual based on information on high biomass accumulation. However, whatever the strategies, they need to be based on reliable information

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

The bii4africa dataset of faunal and floral population intactness estimates across Africa’s major land uses

Sub-Saharan Africa is under-represented in global biodiversity datasets, particularly regarding the impact of land use on species’ population abundances. Drawing on recent advances in expert elicitation to ensure data consistency, 200 experts were convened using a modified-Delphi process to estimate ‘intactness scores’: the remaining proportion of an ‘intact’ reference population of a species group in a particular land use, on a scale from 0 (no remaining individuals) to 1 (same abundance as the reference) and, in rare cases, to 2 (populations that thrive in human-modified landscapes). The resulting bii4africa dataset contains intactness scores representing terrestrial vertebrates (tetrapods: ±5,400 amphibians, reptiles, birds, mammals) and vascular plants (±45,000 forbs, graminoids, trees, shrubs) in sub-Saharan Africa across the region’s major land uses (urban, cropland, rangeland, plantation, protected, etc.) and intensities (e.g., large-scale vs smallholder cropland). This dataset was co-produced as part of the Biodiversity Intactness Index for Africa Project. Additional uses include assessing ecosystem condition; rectifying geographic/ taxonomic biases in global biodiversity indicators and maps; and informing the Red List of Ecosystems

The bii4africa dataset of faunal and floral population intactness estimates across Africa’s major land uses

Sub-Saharan Africa is under-represented in global biodiversity datasets, particularly regarding the impact of land use on species’ population abundances. Drawing on recent advances in expert elicitation to ensure data consistency, 200 experts were convened using a modified-Delphi process to estimate ‘intactness scores’: the remaining proportion of an ‘intact’ reference population of a species group in a particular land use, on a scale from 0 (no remaining individuals) to 1 (same abundance as the reference) and, in rare cases, to 2 (populations that thrive in human-modified landscapes). The resulting bii4africa dataset contains intactness scores representing terrestrial vertebrates (tetrapods: ±5,400 amphibians, reptiles, birds, mammals) and vascular plants (±45,000 forbs, graminoids, trees, shrubs) in sub-Saharan Africa across the region’s major land uses (urban, cropland, rangeland, plantation, protected, etc.) and intensities (e.g., large-scale vs smallholder cropland). This dataset was co-produced as part of the Biodiversity Intactness Index for Africa Project. Additional uses include assessing ecosystem condition; rectifying geographic/taxonomic biases in global biodiversity indicators and maps; and informing the Red List of Ecosystems