75 research outputs found
Diversity and Global Distribution of Viruses of the Western Honey Bee, Apis mellifera
Funding: This research was permitted and funded by the COLOSS network (https://coloss.org/).Peer reviewedPublisher PD
Spin Caloritronics
This is a brief overview of the state of the art of spin caloritronics, the
science and technology of controlling heat currents by the electron spin degree
of freedom (and vice versa).Comment: To be published in "Spin Current", edited by S. Maekawa, E. Saitoh,
S. Valenzuela and Y. Kimura, Oxford University Pres
Beyond a phenomenological description of magnetostriction
We use ultrafast x-ray and electron diffraction to disentangle spin-lattice
coupling of granular FePt in the time domain. The reduced dimensionality of
single-crystalline FePt nanoparticles leads to strong coupling of magnetic
order and a highly anisotropic three-dimensional lattice motion characterized
by a- and b-axis expansion and c-axis contraction. The resulting increase of
the FePt lattice tetragonality, the key quantity determining the energy barrier
between opposite FePt magnetization orientations, persists for tens of
picoseconds. These results suggest a novel approach to laser-assisted magnetic
switching in future data storage applications.Comment: 12 pages, 4 figure
Modeling βpsychosisβ in vitro by inducing disordered neuronal network activity in cortical brain slices
# The Author(s) 2009. This article is published with open access at Springerlink.com Introduction Dysregulation of neuronal networks has been suggested to underlie the cognitive and perceptual abnor-malities observed schizophrenia. Discussions An in vitro model of psychosis is proposed based on the two different approaches to cause aberrant networ
The Functions of Mediator in Candida albicans Support a Role in Shaping Species-Specific Gene Expression
The Mediator complex is an essential co-regulator of RNA polymerase II that is conserved throughout eukaryotes. Here we present the first study of Mediator in the pathogenic fungus Candida albicans. We focused on the Middle domain subunit Med31, the Head domain subunit Med20, and Srb9/Med13 from the Kinase domain. The C. albicans Mediator shares some roles with model yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe, such as functions in the response to certain stresses and the role of Med31 in the expression of genes regulated by the activator Ace2. The C. albicans Mediator also has additional roles in the transcription of genes associated with virulence, for example genes related to morphogenesis and gene families enriched in pathogens, such as the ALS adhesins. Consistently, Med31, Med20, and Srb9/Med13 contribute to key virulence attributes of C. albicans, filamentation, and biofilm formation; and ALS1 is a biologically relevant target of Med31 for development of biofilms. Furthermore, Med31 affects virulence of C. albicans in the worm infection model. We present evidence that the roles of Med31 and Srb9/Med13 in the expression of the genes encoding cell wall adhesins are different between S. cerevisiae and C. albicans: they are repressors of the FLO genes in S. cerevisiae and are activators of the ALS genes in C. albicans. This suggests that Mediator subunits regulate adhesion in a distinct manner between these two distantly related fungal species
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