57 research outputs found

    NÍVEIS DE ESTRESSE EM TAXISTAS

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    Este estudo teve como objetivo verificar os níveis de estresse em motoristas de táxi em Aracaju/SE, utilizando o Inventário de Sintomas de Estresse de Lipp (ISEL). Foram entrevistados 72 motoristas de táxi os quais 48,6% apresentaram estresse e 51,4% não apresentaram estresse. A idade média bem como o tempo de serviço na presença ou não do quadro de estresse foi semelhante (p>0,05). Sintomas físicos associados ao estresse são os problemas de memória e a tensão muscular. O ato de pensar constantemente em um só assunto mostrou associação significativa com os sinais de estresse (

    Diagnosis, management, and follow-up of extensive dermoid cyst of the submental region

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    Dermoid cyst (DC) is a cystic lesion of developmental origin and uncertain etiology that rarely affects the floor of the mouth. We report a case of a large lesion found in the submental and submandibular region in a 25-year-old male patient. Computed tomography revealed extensive hypodense lesion in the submental and submandibular space without peripheral enhancement. The microscopical analysis showed a cystic cavity lined by orthokeratinized stratified squamous epithelium. The cystic capsule was composed of dense fibrous connective tissue containing cutaneous attachments, such as sebaceous and sweat glands. The diagnosis of DC was made. The differential diagnosis of expansive sublingual lesions can be clinically challenging due to the similarity with several lesions frequently observed in this region. Herein, we describe a case of extensive DC arising in the floor of the mouth, presenting clinical, imaging, and microscopical features

    Plasma cell cheilitis: the diagnosis of a disorder mimicking lip cancer

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    Plasma cell cheilitis (PCC) is an inflammatory disorder of unknown etiology that affects the lip. It is characterized histologically by a dense infiltrate of plasma cells with a variety of clinical features. The response to different therapeutic modalities is controversial, especially regarding the effectiveness of corticosteroids. We present a case of a 56-year-old Caucasian man with a painful ulcerated and crusted area in the lower lip, resembling a squamous cell carcinoma or actinic cheilitis. Topical corticosteroid was used for one week, which resulted in partial regression and motivated a biopsy. The histological examination provided the diagnosis of PCC. The patient has been disease-free for six months. We also provide a discussion on the criteria of differential diagnosis and management of this rare condition. See ERRATUM&nbsp

    Generalized hereditary gingival fibromatosis in a child: clinical, histopathological and therapeutic aspects

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    Hereditary gingival fibromatosis (HGF) is a rare genetic condition characterized by slow and progressive gingival enlargement. The gingival overgrowth often delays teeth eruption and may cause serious functional and aesthetic problems. We reported a case of a 10-year-old female child presenting a generalized gingival enlargement covering almost all the maxillary and mandibular teeth and resulted in problems for swallowing, speaking, and poor aesthetics. An incisional biopsy was performed and revealed a hypocellular and hypovascular dense collagenous tissue covered by squamous epithelium exhibiting acanthosis and elongated rete ridges. The diagnosis was HGF. The treatment instituted was an association of gingivectomy with a rigorous program of oral hygiene and follow-up. Herein, we describe a rare non-syndromic case of generalized HGF, including clinical and microscopical features, as well as highlighting the importance of correct diagnosis of this genetic condition

    Trait anxiety affects the orofacial nociceptive response in rats

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    The aims of the present study were to assess the influence of: a) trait anxiety on orofacial pain; and b) orofacial pain on state anxiety. Forty-four rats were initially exposed to the free-exploratory paradigm for the evaluation of their anxiety profiles. In accordance to the parameter "Percentage of time in the novel side", the animals were considered as presenting high or low levels of trait anxiety when presenting values below the 1st quartile, or above the 3rd quartile, respectively. A week later, formalin-1.5% was injected into the upper lip of each animal. The behavioural nociceptive response, characterized by increased orofacial rubbing (OR), was quantified for 30 minutes, as follows: Total time OR (0-30 minutes: total pain), 1st phase OR (0-6 minutes: neurogenic pain), and 2nd phase OR (12-30 minutes: inflammatory pain). Immediately after this test, but still under the effect of formalin, the rats were submitted to the Elevated Plus-maze test (EPM). The results showed that the high trait anxiety individuals presented higher frequency of OR than the low trait anxiety ones, except during the neurogenic pain period. However, no correlation was found between OR frequency and levels of state anxiety presented on the EPM. In conclusion, the animals presenting higher anxiety profiles were the most susceptible to orofacial pain, nevertheless, orofacial pain did not influence state anxiety

    Salivary gland tumors : a 13-year clinicopathologic retrospective study in a Brazilian northeast population

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    The present study aimed to evaluate the clinicopathologic features of salivary gland tumors (SGTs) in a Brazillian northeast population. A retrospective descriptive cross-sectional study was performed (1995-2009). All cases of SGTs diagnosed in a priva

    Effect of green propolis on oral epithelial dysplasia in rats

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    Estudos têm demonstrado que componentes hidrossolúveis da própolis verde, flavonóides, apresentam atividade antitumoral. Forma de Estudo: Estudo experimental. Objetivo: Avaliar o efeito do extrato hidroalcoólico de própolis verde (EPV) sobre displasias epiteliais linguais quimicamente induzidas em ratos. Materiais e Métodos: Neste estudo, foi pincelado DMBA (9,10-dimetil-1,2-benzatraceno) no dorso lingual de ratos 3x/semana, em dias alternados, administrado 100 (PROP1), 200 (PROP2) e 300 mg/kg (PROP3) de EPV (v.o.), durante 20 semanas. A substituição do EPV ou DMBA pelos seus veículos foi usada nos controles positivos (TUM1 e TUM2), negativos (CTR1 e CTR2), respectivamente. O epitélio lingual foi analisado histologicamente, graduado pelo Sistema Binário e classificação OMS, e os dados comparados por análise de variância (ANOVA) (p<0,05). Resultados: O rendimento do EPV foi 41,43% e o teor de flavonóides 0,95±0,44%. Segundo o Sistema Binário, TUM1, TUM2 e PROP1 foram considerados lesões de alto risco, apresentando índices de alterações morfológicas significativamente mais elevados (p<0,05), e os demais de baixo risco. Segundo a classificação OMS, observou-se displasia moderada em TUM e TUM2, leve em PROP1, PROP2 e PROP3, e ausente em CTR1 e CTR2. Conclusão: Sugere-se que o EPV possa desempenhar um papel protetor importante durante a carcinogênese lingual quimicamente induzida em ratos. _________________________________________________________________________________________ ABSTRACT: Studies have demonstrated that flavonoid compounds of green propolis have antitumoral activity. Study Design: Experimental study. Aims: To evaluate the effect of a hydroalcoholic extract of green propolis (EPV) on chemically induced epithelial dysplasias in rat tongues. Methods and Materials: DMBA was brushed on the lingual dorsum of rats 3x/week on alternate days - 100 (PROP1), 200(PROP2) and 300 mg/kg (PROP3) EPV was administered orally for 20 weeks. EPV or DMBA were replaced by their vehicles and applied as positive (TUM1 and TUM2) and negative controls (CTR1 and CTR2), respectively. The lingual epithelium was histologically analyzed and graded according a binary system and the WHO classification; the data were compared using ANOVA (*p<0.05). Results: The EPV yield was 41% and the flavonoid yield was 0.95±0.44%. According to the Binary System, TUM1, TUM2 and PROP1 were considered high risk lesions, with significantly higher morphological alteration rates compared to the other groups (p<0.05), which were considered low risk lesions. Based on the WHO classification, moderate dysplasia was TUM1 and TUM2, mild dysplasia was PROP1, PROP2 and PROP3, and non-dysplastic epithelium was CTR1 and CTR2. Conclusion: EPV seems to play an important protective role against chemically-induced lingual carcinogenesis in rats

    Clinicopathologic features of nasopalatine duct cysts:a retrospective study in two Brazilian oral and maxillofacial pathology referral centers

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    Nasopalatine duct cyst (NDC) is the most common non-odontogenic cyst in the oral cavity. Clinically it is not difficult to suspect these lesions based on clinical and radiographic appearance. However, the histopathological diagnosis may be difficult due to the broad morphological diversity of these lesions. The objective was to analyze the clinicopathological features of NDCs diagnosed in two oral and maxillofacial pathology services in the Brazilian northeast. A retrospective clinicopathologic study was performed. A total of 18,121 clinical records of oral lesions from two oral and maxillofacial pathology services in Brazil were analyzed (2000-2020). All NDCs cases were revised and demographic, clinical, radiographic, and histopathological data were collected. Among 18,121 diagnoses in the oral pathology services, 45 (0.2%) were NDCs. The series comprises 24 males (53.3%) and 21 females (46.7%), with a mean age of 43.2 years-old. Most lesions were asymptomatic (n = 27, 60%) with an mean size of 2.1 cm. Microscopically, the non-keratinized stratified squamous epithelium was the most common (66.7%). However, in 88.9% of cases, the epithelial lining was varied and composed of two or more types of epithelium. There was no significant association between the type of epithelium and the size of the cysts (p = 0.389). Nerve, blood vessels, hemorrhage, and chronic inflammatory infiltrate were commonly observed. In contrast, there was a low frequency of mucous glands, sebaceous glands, cholesterol clefts, and multinucleated giant cells. The clinical, radiographic, and microscopic findings observed in this study are similar to those reported in the literature. Due to the morphological diversity of NDC, it is needed to correlate its histopathological features with the clinical and radiographic findings to establish a correct diagnosis
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