22 research outputs found
Synchronization of Josephson oscillations in mesa array of BSCCO single crystal through the Josephson plasma waves in base crystal
Using mesa array of single crystal was
demonstrated recently as a promising route to enhance the radiation power
generated by Josephson oscillations in mesas. We study the synchronization in
such an array via the plasma waves in the base crystal. First, we analyze
plasma oscillations inside the base crystal generated by the synchronized mesa
array and the associated dissipation. We then solve the dynamic equation for
superconducting phase numerically to find conditions for synchronization and to
check the stability of synchronized state. We find that mesas are synchronized
when the cavity resonance of mesas matches with that of the base crystal. An
optimal configuration of mesa arrays is also obtained.Comment: 6.3 pages, 7 figure
HPLC Determination and Pharmacokinetic Study of Homoeriodictyol-7-O-â- D- glucopyranoside in Rat Plasma and Tissues
Homoeriodictyol-7-O-β-D-glucopyranoside (HEDT-Glu) was isolated from Viscum coloratum and identified by MS, 1H- and 13C-NMR. A HPLC method was developed for determination of HEDT-Glu in rat plasma and tissues. All biological samples were pretreated by protein precipitation with acetone. Vanillin was selected as internal standard. The mobile phase consisted of methanol–water–glacial acetic acid (45 : 55 : 0.5, v/v/v). Good linearity were observed over the concentration ranges of 0.1—200.0 μg·ml−1 in rat plasma and 0.05—5.0 μg·ml−1 in tissues. Both intra- and inter-day precisions of HEDT-Glu, expressed as the relative standard deviation, were less than 13.1%. Accuracy, expressed as the relative error, ranged from −0.8 to 5.4% in plasma and from −5.6 to 9.4% in tissues. The mean extraction recovery of HEDT-Glu was above 73.17% in biological samples. The described assay method was successfully applied to the pre-clinical pharmacokinetic study of HEDT-Glu. After intravenous administration of HEDT-Glu to rat, AUC and CLtot were 16.04±3.19 μg·h·ml−1 and 0.85±0.17 l·kg−1·h−1, respectively. T1/2,α and t1/2,β were 0.06±0.01 h and 1.27±0.31 h, respectively. HEDT-Glu was cleared from the blood and mainly distributed to the liver and small intestine