Serum Cytokines Profiles and Some Salivary Parameters in Chronic Periodontitis Patients in Mosul - Iraq

The aim of study is to measure serum IL-1 ?, IL-6, IL-8, IFN-? and TNF-? levels, and some of salivary parameters like sIgA, total protein and peroxidase specific activity in patients with chronic periodontitis in Mosul and compared them with control group. The study population consisted of 91 patients suffering from chronic periodontitis, aging between ?18-73 years old and 18 control samples collected from healthy individuals ranged between 23-35 years old. Blood and saliva samples were collected from patients and control groups to measure serum IL-1?, IL-6, IL-8, IFN-? and TNF-? ,and salivary sIgA , total protein levels and peroxidase specific activity . In the present study most of patients were showed localized chronic periodontitis, ranging from severe 57% to moderate infection 43%.Salivary sIgA level showed significant increase in chronic periodontitis comparing with control group.Patients group showed significance correlation between serum TNF-? with serum IL-1?, IL-6 and IFN-? levels. Also serum IL-1? level showed significant correlation with salivary sIgA and total protein levels. Furthermore negative correlations were detected between salivary sIgA and serum IL-8, as well asbetween salivary total protein and peroxides specific activity. According to periodontal pocket depth, serum IL-1?, IFN-?, salivary sIgA levels and salivary peroxidase specific activity showed significance increase in patients with 7mm pocket depth. In the present study, most of patients showed localized chronic periodontitis. Salivary sIgA level showed significant increase in chronic periodontitis comparing with control group. Serum IL-1?, IFN-?, salivary sIgA levels and salivary peroxidase specific activitywere linked with 7mm periodontal pocket depth

Detection of Herpes Viruses in Aggressive Periodontitis Patients in Mosul

The aim of the study is to estimate the frequency of herpes viruses HCMV, EBV1 and HSV in periodontal pocket samples of aggressive periodontitis patients. This study was carried out on total number of 24 Aggressive Periodontitis patients, 14 (58%) males and 10 (42%) females, aging between 20-?40 years old). Periodontal pocket samples were collected from three deepest pocket sites and nested PCR technique was used to detect HCMV, EBV and HS

Comparison among four proposed direct blood culture microbial identification methods using MALDI-TOF MS

SummaryMatrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry facilitates rapid and accurate identification of pathogens, which is critical for sepsis patients.In this study, we assessed the accuracy in identification of both Gram-negative and Gram-positive bacteria, except for Streptococcus viridans, using four rapid blood culture methods with Vitek MALDI-TOF-MS. We compared our proposed lysis centrifugation followed by washing and 30% acetic acid treatment method (method 2) with two other lysis centrifugation methods (washing and 30% formic acid treatment (method 1); 100% ethanol treatment (method 3)), and picking colonies from 90 to 180min subculture plates (method 4). Methods 1 and 2 identified all organisms down to species level with 100% accuracy, except for Streptococcus viridans, Streptococcus pyogenes, Enterobacter cloacae and Proteus vulgaris. The latter two were identified to genus level with 100% accuracy. Each method exhibited excellent accuracy and precision in terms of identification to genus level with certain limitations

Serum and Salivary Markers in Aggressive Periodontitis Patients In Mosul

This study also showed direct correlation between serum IL-1? and Salivary peroxidase, also between (IgA, total protein and peroxidase Specific activity in saliva). Finally presence of direct correlation between peroxidase specific activity and total protein. The aims of the study is to assess and compare serum levels of cytokines (IL-8,IL-6,IL-1?,IFN-? and TNF-?) and salivary markers (sIgA, peroxidase, peroxidase specific activity and total protein) in aggressive periodontitis patients and periodontally healthy individuals in Mosul. This study was carried out on a total number of 49 subjects, 24 Aggressive Periodontitis patients,14 males and 10 females, aging between 20 - ?40 years, and 25 healthy subjects as control group which consisted of 14 males and 11 females aging between 20-45 years. All patients were systemically healthy. Five ml of venous blood and saliva were withdrawn from each patient and control subject, for assessments of serum cytokines (IL-8,IL-6,IL-1?,IFN-? and TNF-? ) and salivary markers (sIgA, total protein and peroxidase specific activity) usin

Refractory Shock Secondary to Denosumab-induced Severe Hypocalcaemia

Denosumab is one of the most commonly used antiresorptive drugs for osteoporosis treatment and the prevention of skeletal-related events in cancer patients. The purpose of this case report is to highlight potentially life-threatening severe hypocalcaemia as a side effect of denosumab complicated by refractory shock that failed to respond to medical management including intravenous calcium, vasopressors and inotropes in an elderly man with a history of prostatic cancer

مهارات إدارة الوقت وعلاقتها بقلق الاختبارات لدى طلبة كلية التربية الرياضية في جامعة اليرموك

هدف المقال التعرف إلى مستوى مهارات إدارة الوقت وعلاقتها بقلق الاختبارات لدى طلبة كلية التربية الرياضية في جامعة اليرموك تبعاً لمتغيرات (الجنس والسنة الدراسية).تم استخدام المنهج الوصفي والمنهج الارتباطي، وتكونت عينة الدراسة من (377) طالباً وطالبة ممن هم على مقاعد الدراسة للفصل الدراسي الثاني من العام الجامعي 2021/2022، تم اختيارهم بالطريقة الطبقية العشوائية، تم جمع البيانات باستخدام مقياس إدارة الوقت المصمم من قبل (Britton and Tesser, 1991) المكون من (35) موزعة على ثلاثة مجالات هي (التخطيط قصير المدى، والموقف من الوقت، والتخطيط طويل المدى)، ومقياس قلق الاختبار المعرفي المصمم من قبل (Núñez-Peña, 2016) المكون من (14) فقرة. أظهرت النتائج بأن مستوى مهارات إدارة الوقت لدى عينة الدراسة جاءت بدرجة متوسطة على المقياس ككل، ومستوى قلق الاختبار لدى عينة الدراسة جاء بدرجة متوسطة، وعدم جود فروق ذات دلالة إحصائية في مستوى مهارات إدارة الوقت وقلق الاختبارات لدى عينة الدراسة تبعا لمتغيري الجنس والسنة الدراسية، كما أظهرت النتائج وجود علاقة ارتباطية ذات دلالة احصائية سلبية بين مهارات إدارة الوقت وقلق الاختبار لدى طلبة كلية التربية الرياضية في جامعة اليرموك. أوصى الباحثون بعقد ورش تدريبية للطلبة لتطوير مهاراتهم في إدارة الوقت، وتخصيص جلسات ارشادية خلال الفصول الدراسية للطلبة الذين يتعرضون لقلق الاختبار المفرط كإجراءات وقائية للتعامل مع مواقف وقلق الاختبارات. The article aimed to identify the level of time management skills and its relationship with test anxiety among physical education students at Yarmouk University in light of various variable such as gender, university, and number of playing years. The study used the descriptive correlational method. The sample consisted of (377) male and female students who are studying for the second semester from the academic year 2021/2022. The time management scale which was adopted by B. Britton and A. Tesser included (35) items, distributed to three dimensions: short-range planning, time attitudes, long-range planning, and cognitive test anxiety scale which was adopted by M. Núñez-Peña, M. Suárez-Pellicioni and R. Bono included (14) items was as a tools for collection. The study showed that the level of time management skills of the study sample was moderate on the fields as a whole and the level of cognitive test anxiety of the study sample was moderate and that there were statistically significant negative between the levels of time management skills with anxiety among physical education students at Yarmouk University. The study recommend the necessity of necessity of enhancing time management skills through the use of sports management experts in holding training workshops on how to plan time management to develop students\u27 skills and modify their attitudes in dealing with time wastes

Diabesity in the Arabian Gulf: Challenges and Opportunities

Diabesity (diabetes associated with obesity) is a major global and local public health concern, which has almost reached an epidemic order of magnitude in the countries of the Arabian Gulf and worldwide. We sought to review the lifestyle trends in this region and to highlight the challenges and opportunities that health care professionals face and attempt to address and correct them. In this regard, we aimed to review the regional data and widely held expert opinions in the Arabian Gulf and provide a thematic review of the size of the problem of diabesity and its risk factors, challenges, and opportunities. We also wished to delineate the barriers to health promotion, disease prevention, and identify social customs contributing to these challenges. Lastly, we wished to address specific problems with particular relevance to the region such as minimal exercise and unhealthy nutrition, concerns during pregnancy, the subject of childhood obesity, the impact of Ramadan fasting, and the expanding role of bariatric surgery. Finally, general recommendations for prevention, evidence-based, and culturally competent management strategies are presented to be considered at the levels of the individual, community, and policymakers

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Gestion hospitalière à l'ère de l'Anthropocène : une analyse internationale des systèmes de contrôle de gestion basés sur le Lean et de l’aliénation des infirmières dans les blocs opératoires.

In the Anthropocene, healthcare systems face unprecedented challenges from increases in the aging population and expanding needs for acute and aged care services. To cope, hospitals are applying Lean-based management control systems (MCSs) to improve their efficiency and reliability by streamlining their existing processes. While literature shows the adoption of Lean-based MCSs in hospitals may lead to some significant productivity enhancements, the consequences of this new performance management approach for healthcare professionals is understudied. This thesis examines the impact of Lean-based MCSs on operating theatre nurses. Fieldwork was conducted between October 2016 and January 2019 in two countries, France, and Australia. It comprised 230 hours of non-participant observations and 47 semi-structured interviews. Findings revealed differences in how the MCSs were experienced—positively or negatively—between staff working at the two sites and the factors influencing such experiences.This research is the first to present an in-depth qualitative analysis of the ways Lean-based MCSs are implemented in operating theatres and how they are experienced by nursing staff. It is also the first international comparative study covering this subject and the first to provide a conceptual foundation for understanding the impacts of Lean-based MCSs in high acuity settings. This research not only contributes to the body of literature on the future of healthcare in the Anthropocene, it provides a theoretical foundation for future investigations of Lean and its consequences on healthcare staff.Les hôpitaux, et plus généralement les systèmes de soins, font face à des défis sans précédent dans notre ère moderne, l’ère de l’anthropocène : population croissante et vieillissante, augmentation de l’espérance de vie, prévalence des maladies chroniques et modifications des besoins de soins. Pour y faire face, ils se tournent de plus en plus vers l’adoption de nouveaux Systèmes de Contrôle de Gestion (SCG) basés sur la philosophie japonaise du Lean Management. Bien que la littérature scientifique montre que l’adoption de pratiques inspirées du Lean peut en effet conduire à des améliorations significatives de la productivité et de l’efficience, les conséquences organisationnelles de ces nouvelles approches pour les professionnels de santé restent encore peu étudiées. Cette thèse examine l’impact des SCG-Lean sur les infirmières des blocs opératoires. Les travaux empiriques ont été menés entre 2016 et 2019 en France et en Australie. Les résultats de la recherche révèlent comment et pourquoi les SCG-Lean peuvent être vécus comme aliénants ou non-aliénants. Cette recherche est la première à présenter une analyse qualitative approfondie de la mise en œuvre des SCG-Lean dans les blocs opératoires et de leurs effets sur le personnel infirmier. La thèse est la première étude comparative internationale sur ce sujet et la première à fournir une base conceptuelle pour comprendre les impacts des SCG-Lean dans des environnements de haute fiabilité comme les blocs opératoires. Cette recherche contribue à la littérature sur l’avenir des hôpitaux à l’ère de l’Anthropocène et fournit un fondement théorique pour les futures études examinant les SCG et leurs conséquences sur les employés