69 research outputs found
The Role of Horticultural Therapy in Promoting Physical and Mental Health
Horticultural therapy is a valuable method for promoting mental health as well as physical well-being by involving individuals in the process of planting, nurturing, and appreciating plants. This practice is particularly effective in mental health education. By reviewing recent literature, this paper focuses on the role of horticultural therapy in reducing stress, regulating emotions, enhancing self-knowledge, promoting social interaction, and facilitating physical rehabilitation. The paper describes the therapy’s implementation and methods for evaluating its effectiveness. The findings indicate that horticultural therapy can significantly reduce stress, improve emotional states, increase self-awareness. These results are significant for mental health education
The Popularization and Promotion Strategy of Horticultural Therapy in College Students’s Life Education
Horticultural therapy is a nature-oriented therapy that has great application value and practical significance in the life education of college students. This article first explains the significance of horticultural activities in life education from the perspective of physical and mental health, observation and thinking ability, and social interaction ability. Then, it explores the ways to popularize and promote the application of horticultural activities in the life education of college students through the establishment of relevant courses and horticultural societies, strengthening teacher training, carrying out practical activities, and strengthening publicity. These measures will help improve the physical and mental health level of college students, cultivate their observation and thinking ability, enhance their social interaction ability, and also contribute to improving the quality of college students' life education
Numerical investigation on the electrical transmission ability of a shearing powder layer
International audienceRecent developments in powder technology gave birth to a new lubricant – powder lubricant. Compared to liquid lubricant, powder lubricant like graphite powder has several advantages, such as good electrical conductivity and good thermal resistance. Such advantages are especially appreciated in sliding electrical contacts. Thus, the study of the electrical transmission ability of a shearing powder layer under different dy-namical constraints appears to have a great interest. Recent works allowed to model the coupling of mechanical and electrical effects in a discrete medium. This algorithm was extended to study the electrical properties of a shearing powder layer with Discrete Element Method. The mechanical and electrical behaviors of the sample were studied in different dynamical regimes, characterized by the inertial number I. The results exhibit an interesting relationship between the average contact resistance and the inertial number I. An exponential increase of the sample's electrical resistance as well as the induced electrical noise are observed closed to the dense flow limit. Such observations underline the fact that to ensure the electrical transmission ability of the powder layer, one must keep the particle size and shear rate small, and a sufficiently large pressure
Boosting Adversarial Attacks by Leveraging Decision Boundary Information
Due to the gap between a substitute model and a victim model, the
gradient-based noise generated from a substitute model may have low
transferability for a victim model since their gradients are different.
Inspired by the fact that the decision boundaries of different models do not
differ much, we conduct experiments and discover that the gradients of
different models are more similar on the decision boundary than in the original
position. Moreover, since the decision boundary in the vicinity of an input
image is flat along most directions, we conjecture that the boundary gradients
can help find an effective direction to cross the decision boundary of the
victim models. Based on it, we propose a Boundary Fitting Attack to improve
transferability. Specifically, we introduce a method to obtain a set of
boundary points and leverage the gradient information of these points to update
the adversarial examples. Notably, our method can be combined with existing
gradient-based methods. Extensive experiments prove the effectiveness of our
method, i.e., improving the success rate by 5.6% against normally trained CNNs
and 14.9% against defense CNNs on average compared to state-of-the-art
transfer-based attacks. Further we compare transformers with CNNs, the results
indicate that transformers are more robust than CNNs. However, our method still
outperforms existing methods when attacking transformers. Specifically, when
using CNNs as substitute models, our method obtains an average attack success
rate of 58.2%, which is 10.8% higher than other state-of-the-art transfer-based
attacks
PE-SERF: A sensitivity-improved experiment to measure JHH in crowded spectra.
Aiming at facilitating the analysis of molecular structure, the gradient-encoded selective refocusing methods (G-SERF) and a great number of its variants for measuring proton-proton coupling constants have been proposed. However, the sensitivity is an issue in the 2D gradient-encoded experiments, because the signal intensity is determined by the slice thickness of the sample that depends on encoding gradient and the bandwidth of selective pulses which is limited by the smallest chemical shift difference of any two coupled protons. Here, we present a method dubbed PE-SERF (perfect echo selective refocusing) which can determine all JHH values involving a selected proton with improved sensitivity compared to original G-SERF experiment. The modules of perfect echo involving selective pulses and gradient-encoded selective refocusing are combined in the method, so that the unwanted J couplings arising from coupled spin pairs in the same sample slice would be nullified. In this way, instead of single proton, a pair of coupled protons is allowed to share a sample slice, and thus the slice thickness can be increased and the spectral sensitivity can be improved. The performance of the method is demonstrated by experiments on quinine and strychnine
PE-SERF: A sensitivity-improved experiment to measure J HH in crowded spectra
Abstract(#br)Aiming at facilitating the analysis of molecular structure, the gradient-encoded selective refocusing methods (G-SERF) and a great number of its variants for measuring proton-proton coupling constants have been proposed. However, the sensitivity is an issue in the 2D gradient-encoded experiments, because the signal intensity is determined by the slice thickness of the sample that depends on encoding gradient and the bandwidth of selective pulses which is limited by the smallest chemical shift difference of any two coupled protons. Here, we present a method dubbed PE-SERF (perfect echo selective refocusing) which can determine all J HH values involving a selected proton with improved sensitivity compared to original G-SERF experiment. The modules of perfect echo involving selective pulses and gradient-encoded selective refocusing are combined in the method, so that the unwanted J couplings arising from coupled spin pairs in the same sample slice would be nullified. In this way, instead of single proton, a pair of coupled protons is allowed to share a sample slice, and thus the slice thickness can be increased and the spectral sensitivity can be improved. The performance of the method is demonstrated by experiments on quinine and strychnine
Overview of the Large-Scale Biosphere–Atmosphere Experiment in Amazonia Data Model Intercomparison Project (LBA-DMIP)
A fundamental question connecting terrestrial ecology and global climate change is the sensitivity of key terrestrial biomes to climatic variability and change. The Amazon region is such a key biome: it contains unparalleled biological diversity, a globally significant store of organic carbon, and it is a potent engine driving global cycles of water and energy. The importance of understanding how land surface dynamics of the Amazon region respond to climatic variability and change is widely appreciated, but despite significant recent advances, large gaps in our understanding remain. Understanding of energy and carbon exchange between terrestrial ecosystems and the atmosphere can be improved through direct observations and experiments, as well as through modeling activities. Land surface/ecosystem models have become important tools for extrapolating local observations and understanding to much larger terrestrial regions. They are also valuable tools to test hypothesis on ecosystem functioning. Funded by NASA under the auspices of the LBA (the Large-Scale Biosphere–Atmosphere Experiment in Amazonia), the LBA Data Model Intercomparison Project (LBA-DMIP) uses a comprehensive data set from an observational network of flux towers across the Amazon, and an ecosystem modeling community engaged in ongoing studies using a suite of different land surface and terrestrial ecosystem models to understand Amazon forest function. Here an overview of this project is presented accompanied by a description of the measurement sites, data, models and protocol
miR-27b inhibits fibroblast activation via targeting TGFB signaling pathway
Background: MicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regulates pulmonary fibroblast activation.Results: We found that miR-27b was down-regulated in fibrotic lungs and fibroblasts from an experimental mouse model of pulmonary fibrosis. The overexpression of miR-27b with a lentiviral vector inhibited TGFB1-stimulated mRNA expression of collagens (COL1A1, COL3A1, and COL4A1) and alpha-smooth muscle actin, and protein expression of Col3A1 and alpha-smooth muscle actin in LL29 human pulmonary fibroblasts. miR-27b also reduced contractile activity of LL29. TGFB receptor 1 and SMAD2 were identified as the targets of miR-27b by 3'-untranslated region luciferase reporter and western blotting assays.Conclusions: Our results suggest that miR-27b is an anti-fibrotic microRNA that inhibits fibroblast activation by targeting TGFB receptor 1 and SMAD2. This discovery may provide new targets for therapeutic interventions of idiopathic pulmonary fibrosis.Peer reviewedPhysiological SciencesOklahoma Center for Respiratory and Infectious Disease
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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