Making sense of mistakes in managerial careers

Purpose: The paper provides initial findings on the causes and consequences of problematic mid‐career work‐role transitions – self‐reported career mistakes described by individuals in terms of a mismatch between expectations and reality. Design/methodology/approach: This exploratory study uses in‐depth interviews based on critical incident technique (CIT) to elicit accounts of problematic work‐role transitions. Findings: Participants reported mismatches arose because their expectations were based on their prior experience, rather than upon information provided by the organisation during the course of the recruitment process. These mismatches stimulated very active sense making on the part of participants, largely focused on finding ways to make their continuation in the role tolerable. Research limitations/implications: The present study, which is exploratory in nature, involved a small sample size, and the use of retrospective accounts. The findings are therefore preliminary and may not be representative of mid‐career managers' experience with problematic work role transitions. However, they confirm the relevance of career mistakes to organisations and individuals and indicate a need for further research on the subject. Practical implications: The study suggested managers moving post in mid‐career bring to their new role a range of expectations based upon prior experience, rather than the recruitment process. Further study is needed, but these findings have significant implications for organisations, in that they suggest recruitment processes must provide information in a manner which might overcome or correct these prior assumptions. Originality/value: The subject of career mistakes has received little treatment in the organisational side of the careers literature, and yet is of everyday concern to organisations and individuals

The salience of boundaries :strategies of distinction, boundary reification and knowledge sharing in a nascent field of practice

PhD ThesisThe practice of knowledge sharing across socio-epistemic boundaries is one of the key areas of inquiry in Practice-Based Studies of knowledge and learning. A considerable body of work dedicated to issues of boundary transcendence has been developed by scholars working in this tradition. The main themes of this literature focus on the idea of bridging boundaries and include boundary-spanning practices, boundary spanners and brokers, and boundary objects. Due to its disproportionate reliance on a consensual and harmonious view of the practice of knowledge sharing, this approach has resulted in (implicitly) treating boundaries as structural givens. Such a conceptualization runs contrary to the predominant view of social and symbolic boundaries in social science, where they are commonly acknowledged to be enacted and relational phenomena. This thesis seeks to contribute to the considerably less developed strand of Practice-Based Studies of knowledge and learning that draws upon these insights and explores the themes of boundary salience, distinction, and reification. The empirical foundation for the thesis is a case study of a Regional Innovation Strategy (RIS) project, funded by the European Commission as part of the Lisbon Strategy for Europe and based in one of the New Member States that acceded to the European Union in 2004. The project was a partnership between three European regions and eight organisations. The key premise of the project was the idea of knowledge transfer from regions with experience of developing regional innovation strategies under the EC aegis to the focal New Member State region. As such, the project represented a heterogeneous knowledge-sharing context, where multiple boundaries could be expected to come into play. The main findings of the thesis reveal a far from harmonious nature of the practice of knowledge sharing associated with the project. The most salient boundary was found to be a pragmatic knowledge boundary, which polarised the nascent field of regional innovation development in the focal region. ‘Knowledge sharing’ took the form of a struggle over the definition of competence within the field, and thus over field dominance. The study identifies first-order and second-order strategies of distinction ii deployed by each of the opposing parties: the former included perspective-pushing, exploitation, and opportunity hoarding; the latter were knowledge transfer, consensus building, and collaboration. The study also identifies a set of six paired practices which constituted both the boundary work and the practice work between the two opposing groups. These practices were found to fall into two categories associated with the relative position of power of those practicing them, i.e. strong and weak practices. Eventually, the struggle for field dominance ended in the concession of defeat by one of the parties, which was immediately followed by the euphemization of the relations across the pragmatic boundary

The effect of incremental inclusion of whole grain wheat in the diet of growing turkeys on growth performance, feed conversion ratio, cecal health, and digesta characteristics

This study was conducted to determine the effects of adding incremental amounts of whole grain wheat (0, 100, and 200 g per kilogram of feed) to the diet of growing turkey poults on growth performance, feed efficiency, digesta pH, and the incidence of cecal distension. Seventy two, 6-wk-old commercial line turkeys were blocked by live weight and randomly allocated to 1 of 3 dietary treatment (n = 4 pens/treatment). Turkeys were offered their respective treatments for the duration of the study. Feed offered and refused and body weights were determined weekly. At 63 d of age 12 turkeys from each treatment were euthanized and crop contents were collected and weighed, pH of gizzard and cecal digesta measured, and ceca and cecal contents visually scored. At 84 d of age, all remaining turkeys were euthanized and the same sampling procedure repeated. Feed conversion ratio was poorer in those turkeys offered diets containing whole grain wheat (P < 0.05), declining quadratically (P < 0.005) as the proportion of whole grain wheat (WGW) in the diet increased. The proportion of WGW found in the crop post-mortem reflected whole wheat inclusion rates of the diets. The pH of gizzard contents at 63 d was lower in turkeys receiving diets supplemented with WGW, declining quadratically (P = 0.005) as the proportion of WGW in the diet increased. However, this difference in gizzard pH was not apparent at 84 d of age. Cecal content pH, cecal visual appearance scores, and cecal content visual appearance scores were not affected by the inclusion of WGW to the diet. The inclusion of WGW to the diets of growing turkeys reduces growth performance and feed efficiency suggesting that the addition of whole wheat may have reduced the nutritional quality of the diet as a whole

Reduction in wound healing complications and infection rate by lumbar CSF drainage after decompressive hemicraniectomy

Objective: Wound healing disorders and surgical site infections are the most frequently encountered complications after decompressive hemicraniectomy (DHC). Subgaleal CSF accumulation causes additional tension of the scalp flap and increases the risk of wound dehiscence, CSF fistula, and infection. Lumbar CSF drainage might relieve subgaleal CSF accumulation and is often used when a CSF fistula through the surgical wound appears. The aim of this study was to investigate if early prophylactic lumbar drainage might reduce the rate of postoperative wound revisions and infections after DHC. Methods: The authors retrospectively analyzed 104 consecutive patients who underwent DHC from January 2019 to May 2021. Before January 2020, patients did not receive lumbar drainage, whereas after January 2020, patients received lumbar drainage within 3 days after DHC for a median total of 4 (IQR 2-5) days if the first postoperative CT scan confirmed open basal cisterns. The primary endpoint was the rate of severe wound healing complications requiring surgical revision. Secondary endpoints were the rate of subgaleal CSF accumulations and hygromas as well as the rate of purulent wound infections and subdural empyema. Results: A total of 31 patients died during the acute phase; 34 patients with and 39 patients without lumbar drainage were included for the analysis of endpoints. The predominant underlying pathology was malignant hemispheric stroke (58.8% vs 66.7%) followed by traumatic brain injury (20.6% vs 23.1%). The rate of surgical wound revisions was significantly lower in the lumbar drainage group (5 [14.7%] vs 14 [35.9%], p = 0.04). A stepwise linear regression analysis was used to identify potential covariates associated with wound healing disorder and reduced them to lumbar drainage and BMI. One patient was subject to paradoxical herniation. However, the patient's symptoms rapidly resolved after lumbar drainage was discontinued, and he survived with only moderate deficits related to the primary disease. There was no significant difference in the rate of radiological herniation signs. The median lengths of stay in the ICU were similar, with 12 (IQR 9-23) days in the drainage group compared with 13 (IQR 11-23) days in the control group (p = 0.21). Conclusions: In patients after DHC and open basal cisterns on postoperative CT, lumbar drainage appears to be safe and reduces the rate of surgical wound revisions and intracranial infection after DHC while the risk for provoking paradoxical herniation is low early after surgery

Biological activity of faba beans proanthocyanidins

The objective of the experiment was to determine whether small amounts of proanthocyanidins (0.1 and 0.3%) may increase the antioxidative properties of the rat diet without exerting an antinutritional effect. Proanthocyanidins of faba bean seed coats were extracted with a mixture of acetone and water (70:30) and lyophilized. The amount of proanthocyanidins was two- or fourfold higher in the experimental diets as compared to the control diet. The addition of proanthocyanidin extract had no significant effect on the coefficients of digestibility of crude protein, daily nitrogen retention and the coefficient of biological value of diet protein. In the blood serum of rats fed diets supplemented with proanthocyanidin extract, there was a slightly higher content of vitamin E and alanine aminotransferase activity, while the content of vitamin A and aspartate aminotransferase activity were similar to those of the control group. In the contents of the rat gut (caecum), a lower activity of â -glucuronidase was found as compared to the control group, whereas â -galactosidase was unaffected. The addition of proanthocyanidin extract to diet caused a decrease in the malondialdehyde content in the heart, kidneys, erythrocytes and blood plasma of rats. The results obtained indicate that the amount of proanthocyanidins used did not exert any antinutritional effects, but extended the pool of diet antioxidants and beneficially affected the activity of the large bowel microflora

Needle-free electronically-controlled jet injector treatment with bleomycin and lidocaine is effective and well-tolerated in patients with recalcitrant keloids

Objectives: The treatment of recalcitrant keloids is challenging. Although intralesional bleomycin using conventional needle injectors (CNI) is effective, it has important drawbacks, such as the need for repetitive and painful injections. Therefore, we aimed to evaluate the effectiveness, tolerability and patient satisfaction of intralesional bleomycin with lidocaine administered with a needle-free electronically-controlled pneumatic jet-injector (EPI) in recalcitrant keloids. Methods: This retrospective study included patients with recalcitrant keloids who had received three intralesional EPI-assisted treatments with bleomycin and lidocaine. Effectiveness was assessed using the Patient and Observer Scar Assessment Scale (POSAS) at baseline and four to six weeks after the third treatment. Additionally, treatment related pain scores numeric rating scale, adverse effects, patient satisfaction and Global Aesthetic Improvement Scale (GAIS) were assessed. Results: Fifteen patients with a total of &gt;148 recalcitrant keloids were included. The median total POSAS physician- and patient-scores were respectively 40 and 41 at baseline, and reduced with respectively 7 and 6-points at follow-up (p &lt; 0.001; p &lt; 0.001). The median pain scores during EPI-assisted injections were significantly lower compared to CNI-assistant injections, (2.5 vs. 7.0, respectively (p &lt; 0.001)). Adverse effects were mild. Overall, patients were “satisfied” or “very satisfied” with the treatments (14/15, 93.3%). The GAIS was “very improved” in one patient, “improved” in nine patients and “unaltered” in four patients. Conclusions: EPI-assisted treatment with bleomycin and lidocaine is an effective, well tolerated, patient-friendly alternative for CNI in patients with recalcitrant keloid scars. Randomized controlled trials are warranted to confirm our findings and improve the clinical management of recalcitrant keloids.</p

Craniectomy size and decompression of the temporal base using the altered posterior question-mark incision for decompressive hemicraniectomy

The altered posterior question-mark incision for decompressive hemicraniectomy (DHC) was proposed to reduce the risk of intraoperative injury of the superficial temporal artery (STA) and demonstrated a reduced rate of wound-healing disorders after cranioplasty. However, decompression size during DHC is essential and it remains unclear if the new incision type allows for an equally effective decompression. Therefore, this study evaluated the efficacy of the altered posterior question-mark incision for craniectomy size and decompression of the temporal base and assessed intraoperative complications compared to a modified standard reversed question-mark incision. The authors retrospectively identified 69 patients who underwent DHC from 2019 to 2022. Decompression and preservation of the STA was assessed on postoperative CT scans and CT or MR angiography. Forty-two patients underwent DHC with the standard reversed and 27 patients with the altered posterior question-mark incision. The distance of the margin of the craniectomy to the temporal base was 6.9 mm in the modified standard reversed and 7.2 mm in the altered posterior question-mark group (p = 0.77). There was no difference between the craniectomy sizes of 158.8 mm and 158.2 mm, respectively (p = 0.45), and there was no difference in the rate of accidental opening of the mastoid air cells. In both groups, no transverse/sigmoid sinus was injured. Twenty-four out of 42 patients in the modified standard and 22/27 patients in the altered posterior question-mark group had a postoperative angiography, and the STA was preserved in all cases in both groups. Twelve (29%) and 5 (19%) patients underwent revision due to wound-healing disorders after DHC, respectively (p = 0.34). There was no difference in duration of surgery. Thus, the altered posterior question-mark incision demonstrated technically equivalent and allows for an equally effective craniectomy size and decompression of the temporal base without increasing risks of intraoperative complications. Previously described reduction in wound-healing complications and cranioplasty failures needs to be confirmed in prospective studies to demonstrate the superiority of the altered posterior question-mark incision

Factors of Cortical Plasticity in Brachial Plexus Injury

Cortical plasticity is the brain’s capability of decoding new information through growth and reorganization over our whole life spam. It is the basis for good outcomes after reinnervation and for rehabilitation of adult and obstetric brachial plexus injury. Knowledge about cortical reorganization is crucial to reconstructive surgeons and physiotherapists that aim to give their patients a reasonable prognosis. This chapter intends to present and summarize the current literature on how to detect and quantify cortical plasticity and how research on factors that influence cortical plasticity, mainly in relation to peripheral nerve and more precise brachial plexus injury progresses. Peculiarities of adult and obstetric brachial plexus injuries and their treatment are given. We present techniques that visualize and quantify cortical plasticity with focus on functional imaging like fMRI and nTMS as well as molecular aspects. Future research is needed to understand mechanisms of how molecular changes on a synaptic level of a neuron influence the macroscopic plasticity, to improve rehabilitative resources, to understand the exact prognostic value of nTMS in brachial plexus injury and to investigate the therapeutic capability of rTMS