Modern Methods of Career Guidance as a Social Value of School Youth

Статья содержит информацию о современных методах профориентации, применяемых государственными и общественными организациями в Российской Федерации. На основе анализа источников показано, что при увеличении профессиональной конкуренции среди школьной молодежи увеличивается ценность деятельности по профориентации.The article contains information on modern career guidance methods used by state and public organizations in the Russian Federation. Based on an analysis of the sources, it is shown that with an increase in professional competition among school youth, the value of career counseling activities among schoolchildren increases

Формирование сценариев аналитической деятельности

Розширену аналітику включено до десятки найбільш затребуваних інформаційних технологій. Дослідження процесу формування сценаріїв аналітичної діяльності необхідно для реалізації розширеної аналітики. Сценарії аналітичної діяльності визначають порядок проведення аналітичної діяльності з метою отримання необхідної інформації для прийняття обґрунтованих рішень. Формування сценаріїв включає їх побудову та оптимізацію. Предметом статті є вдосконалення моделі предметної області, відносно якої проводиться аналітична діяльність. Метод об’єктно-орієнтованого моделювання і принципи побудови адаптивних об’єктних моделей використовуються для побудови об’єктної моделі предметної області, що аналізується. Побудовано адаптивну об’єктну модель, яка представляє класи, атрибути та взаємозв’язки як метадані. Використання вдосконаленої моделі предметної області для оптимізації сценаріїв методом сценарних областей призводить до покращення результатів методу оптимізації. Для об’єктної моделі предметної області та сценаріїв розроблено діаграму класів, яка може бути використана як елемент комп’ютерної моделі інформаційно-аналітичної програмної платформи.Advanced analytics is one of the most required information technologies. Research of a scenario formation process of analytical activity is required for advanced analytics realization. Analytical activity scenarios define order of analytical activity conduction for obtainment of necessary information that assist to produce informed decisions. Scenario formation contains of scenarios building and optimization. The subject of the article is improvement of domain model over which analytical activity is performed. Object-oriented modeling method and adaptive object model approach is used to build analyzable domain object model. An adaptive object model that submits classes, attributes and relationships as metadata is built. Use of improving domain model in scenario area method that is used for scenario optimization conducts to enhancement of scenario optimization results. Scenario area method is adopted with account of domain object model building that includes analytical activity scenarios. Class diagram has been developed for domain and scenarios object model and can be used as computer model element of information-analytical program platform.Расширенная аналитика включена в десятку наиболее востребованных информационных технологий. Исследование процесса формирования сценариев аналитической деятельности необходимо для реализации расширенной аналитики. Сценарии аналитической деятельности определяют порядок проведения аналитической деятельности с целью получения необходимой информации для принятия обоснованных решений. Формирование сценариев включает их построение и оптимизацию. Предметом статьи является усовершенствование модели предметной области, относительно которой проводится аналитическая деятельность. Метод объектно-ориентированного моделирования и принципы построения адаптивных объектных моделей используются для построения объектной модели анализируемой предметной области. Построена адаптивная объектная модель, которая представляет классы, атрибуты и взаимосвязи как метаданные. Использование усовершенствованной модели предметной области для оптимизации сценариев методом сценарных областей приводит к улучшению результатов метода оптимизации. Для объектной модели предметной области и сценариев разработана диаграмма классов, которая может быть использована как элемент компьютерной модели информационно-аналитической программной платформы

ПНЕВМОНЭКТОМИЯ У ПАЦИЕНТА С ОСЛОЖНЕННЫМ ТЕЧЕНИЕМ ГРАНУЛЕМАТОЗА ВЕГЕНЕРА

The article describes a clinical case of 42-year old male patient with necrotising granulomatosis with polyangitis (Wegener's granulomatosis) complicated by pulmonary aspergillosis, and due to the latter a life-saving pneumonectomy had to be done  Microbiological tests of surgery specimens detected the cell crowding of mold fungi of Aspergillus fumigatus The histological tests showed necrotising granulomatosis with polyangitis, formation of cavities with fibrotic walls and fungal population; fibrinous-hemorrhagic pleurisy. In one month after surgery the patient was transferred to the rheumatological ward, where biological anti-B-cellular therapy with rituximab was started with a consequent positive outcome.Представлено клиническое наблюдение пациента 42 лет с некротизирующим гранулематозом с полиангиитом (гранулематоз Вегенера), осложненным аспергиллезом легкого, которому по жизненным показаниям пришлось выполнить пневмонэктомию При микробиологическом исследовании операционного материала получен сливной рост плесневых грибов рода Aspergillus fumigatus При гистологическом исследовании ‒ картина некротизирующего гранулематоза с полиангиитом, формирование полостей деструкции с фиброзными стенками и наличием грибковой флоры; фибринозно-геморрагический плеврит. Через месяц после проведенного оперативного вмешательства пациент переведен в ревматологическое отделение, где была начата биологическая анти-В-клеточная терапия ритуксимабом с хорошим эффектом

Фатальное течение гриппа А / H1N1 / 09, осложненного генерализованной нозокомиальной инфекцией

A fatal case of swine flu (А / H1N1 / 09) complicated by generalized nosocomial infection.Фатальное течение гриппа А / H1N1 / 09, осложненного генерализованной нозокомиальной инфекцией

Effect of Gas Atmosphere on Catalytic Behaviour of Zirconia, Ceria and Ceria Zirconia Catalysts in Valeric Acid Ketonization

[EN] Ketonization of valeric acid, which can be obtained by lignocellulosic biomass conversion, was carried out in a fixed bed flow reactor over ZrO2, 5-20 % CeO2/ZrO2 and CeO2 both under hydrogen and nitrogen stream at 628 K and atmospheric pressure. Regardless gas-carrier 10 wt% CeO2/ZrO2 was found to show higher catalytic activity compared to zirconia per se as well as other ceria modified zirconia while ceria per se exhibited very low catalytic activity. All catalysts provided higher acid conversion in H-2 than in N-2 whereas selectivity to 5-nonanone was insensitive to gas atmosphere. XRD, FTIR, UV-Vis DRS, XPS, HRTEM methods were applied to characterize catalysts in reduced and unreduced states simulating corresponding reaction conditions during acid ketonization. XRD did not reveal any changes in zirconia and ceria/zirconia lattice parameters as well as crystalline phase depending on gas atmosphere while insertion of ceria in zirconia caused notable increase in lattice parameter indicating some distortion of crystalline structure. According to XPS, FTIR and UV-Vis methods, the carrier gas was found to affect catalyst surface composition leading to alteration in Lewis acid sites ratio. Appearance of Zr3+ cations was observed on the ZrO2 surface after hydrogen pretreatment whereas only Zr4+ cations were determined using nitrogen as a gas-carrier. These changes of catalyst's surface cation composition affected corresponding activity in ketonization probably being crucial for reaction mechanism involving metal cations catalytic centers for acid adsorption and COO- stabilization at the initial step.Financial support from the Russian Foundation of Basic Research (RFBR Grant No 11-03-94001-CSIC) is gratefully acknowledged. This work was supported by the Federal Program "Scientific and Educational Cadres of Russia'' (Grant No 2012-1.5-12-000-1013-002). The authors also wish to thank Dr. Evgeniy Gerasimov, Dr. Igor Prosvirin, Dr. Demid Demidov from the Department of Physicochemical Methods at the Boreskov Institute of Catalysis for TEM and XPS measurements.Zaytseva, YA.; Panchenko, VN.; Simonov, MN.; Shutilov, AA.; Zenkovets, GA.; Renz, M.; Simakova, IL.... (2013). Effect of Gas Atmosphere on Catalytic Behaviour of Zirconia, Ceria and Ceria Zirconia Catalysts in Valeric Acid Ketonization. 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The beam and detector of the NA62 experiment at CERN

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the K+ → π+ ν bar nu decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. The beam line and detector components are described together with their early performance obtained from 2014 and 2015 data

Scheme Choice and Inverse Kinematics of a Positioning System Based on a Planar Parallel Mechanism

Recent development of the parallel mechanisms theory has resulted in an increase of the actual machines, which are built using the conceptual schemes of such mechanisms. The advantages of parallel kinematics over conventional open-chain design, such as increased stiffness or lower inertia of moving parts, allow, in theory, higher performance rates in pick-and-place or machining applications. However, the practical usage of parallel mechanisms may be problematic due to their drawbacks, such as restricted workspace area and presence of singularities.The paper discusses a modification of the milling machine “Tetra” developed in “Modular Mechanics”, ltd. (BMSTU), which consists of two identical modules based on planar parallel kinematics mechanism. The loss of module stiffness in certain positions of the end-effector was noticed after experiments on the prototype, thus indicating the presence of singularities. Since this problem is a manifestation of fundamental properties of the chosen kinematic scheme, it was decided to change it.A scheme with three linear rails and three drives, as well as a scheme with a single rail and with four drives were considered as alternative options. The first option was discarded because it requires manufacturing a massive base plate. The second option was selected for future development. In this case, as compared to the previously known design, a configuration of the intermediate links was changed. The use of “lambda”-shaped elements makes it possible to distance the drive supports from the end-effector.For a chosen scheme an inverse kinematics problem was solved. Using constraints associated with the placement of all four drive supports on a single rail and stiffness requirements as well, a one single solution was selected among sixteen possible solutions.The further investigation will include a workspace and singularity analysis and an optimization of geometric parameters of the mechanism.</p

PNEUMONECTOMY IN THE PATIENTS WITH THE COMPLICATED COURSE OF WEGENER'S GRANULOMATOSIS

The article describes a clinical case of 42-year old male patient with necrotising granulomatosis with polyangitis (Wegener's granulomatosis) complicated by pulmonary aspergillosis, and due to the latter a life-saving pneumonectomy had to be done  Microbiological tests of surgery specimens detected the cell crowding of mold fungi of Aspergillus fumigatus The histological tests showed necrotising granulomatosis with polyangitis, formation of cavities with fibrotic walls and fungal population; fibrinous-hemorrhagic pleurisy. In one month after surgery the patient was transferred to the rheumatological ward, where biological anti-B-cellular therapy with rituximab was started with a consequent positive outcome

Biological and Physical-Chemical Properties of <i>Yersinia pseudotuberculosis</i> Cultures in the Process of Submerged Cultivation at Various Temperatures

Biological and physical-chemical properties of the pseudotuberculosis agent cultures were shown to be diverse in the process of submerged cultivation at various temperatures. The microbe cultivation at the increased temperature (37°C) was characterized by fast development and death of the population. Decelerated lag phase and extended exponential phase were observed under the conditions of cultivation at low temperature. The culture grown at 27 °C was found to get an intermediate position between those grown at 10 and 37 °C