857 research outputs found
Synaptic transmission as a cooperative phenomenon in confined systems
In this review paper, the theory of synaptic transmission (ST) was developed
and discussed. We used the hypothesis of isomorphism between: (a) the
cooperative behavior of mediators --- acetylcholine molecules (ACh) and
cholinoreceptors in a synaptic cleft with binding into mediator-receptor (AChR)
complexes, (b) the critical phenomena in confined binary liquid mixtures. The
systems of two (or three) nonlinear differential equations were proposed to
find the change of concentrations of ACh, AChR complexes, and ferment
acetylcholinesterase. The main findings of our study: the linear size of the
activation zone was evaluated; the process of postsynaptic membrane activation
was described as a cooperative process; different approximations of ACh
synchronous release were examined; stationary states and types of singular
points were studied for the proposed models of ST; the nonlinear kinetic model
with three order parameters demonstrated a strange-attractor behavior.Comment: 12 pages, 1 figur
Modeling of the Labour Force Redistribution in Investment Projects with Account of their Delay
The mathematical model of the labour force redistribution in investment
projects is presented in the article. The redistribution mode of funds, labour
force in particular, according to the equal risk approach applied to the loss
of some assets due to delay in all the investment projects is provided in the
model. The sample of the developed model for three investment projects with the
specified labour force volumes and their defined unit costs at the particular
moment is given
Constructive solution of highly effective photoenergy module: development and experimental testing
Based on experimental study and computermodeling of working temperature influence on the efficiency of Chinese production silicon solar cells identified temperature dependence of efficiency shows the feasibility of using Chinese production Si-SC in the construction of photovoltaic thermal system, which together with the heat pump is part of a combined system for hot water supply, heating and air conditioning. Based on a detailed analysis of the working temperature influence on the efficiency of photovoltaic processes that determine the solar cells work, it has been developed the optimal construction and technological solution of hybrid solar generated module, the main feature ofwhich is the heat exchange block, designed to reduce the solar cells working temperature. The experimental testing of hybrid modules samples equipped with developed cooling system, high-voltage part of power take-off system demonstrates their reliability and high efficiency which allow to achieve the such module efficiency up to 18.5 %.ΠΠ° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ΅ Ρ ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΡΠΌ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ Π²Π»ΠΈΡΠ½ΠΈΡ ΡΠ°Π±ΠΎΡΠ΅ΠΉ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ Π½Π° ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΊΡΠ΅ΠΌΠ½ΠΈΠ΅Π²ΡΡ
ΡΠΎΠ»Π½Π΅ΡΠ½ΡΡ
ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² ΠΊΠΈΡΠ°ΠΉΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π° Π²ΡΡΠ²Π»Π΅Π½Π° ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ½Π°Ρ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΡ ΠΈΡ
ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ. Π’Π΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ½Π°Ρ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΡ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°Π΅Ρ ΡΠ΅Π»Π΅ΡΠΎΠΎΠ±ΡΠ°Π·Π½ΠΎΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΡΠΎΠ»Π½Π΅ΡΠ½ΡΡ
ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² ΠΊΠΈΡΠ°ΠΉΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π° Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠΎΡΠΎΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠ΅ΠΏΠ»ΠΎΠ²ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ, ΠΊΠΎΡΠΎΡΠ°Ρ Π²ΠΌΠ΅ΡΡΠ΅ Ρ ΡΠ΅ΠΏΠ»ΠΎΠ²ΡΠΌ Π½Π°ΡΠΎΡΠΎΠΌ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ°ΡΡΡΡ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ Π³ΠΎΡΡΡΠ΅Π³ΠΎ Π²ΠΎΠ΄ΠΎΡΠ½Π°Π±ΠΆΠ΅Π½ΠΈΡ, ΠΎΡΠΎΠΏΠ»Π΅Π½ΠΈΡ ΠΈ ΠΊΠΎΠ½Π΄ΠΈΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π²ΠΎΠ·Π΄ΡΡ
Π°. ΠΠ° ΠΎΡΠ½ΠΎΠ²Π΅ Π΄Π΅ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° Π²Π»ΠΈΡΠ½ΠΈΡ ΡΠ°Π±ΠΎΡΠ΅ΠΉ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ Π½Π°
ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠΎΡΠΎΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ², ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡΠΈΡ
ΡΠ°Π±ΠΎΡΡ ΡΠΎΠ»Π½Π΅ΡΠ½ΡΡ
ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ², Π±ΡΠ»ΠΎ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½ΠΎ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ΅ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΠ²Π½ΠΎ-ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ Π³ΠΈΠ±ΡΠΈΠ΄Π½ΠΎΠ³ΠΎ ΡΠΎΠ»Π½Π΅ΡΠ½ΠΎΠ³ΠΎ Π³Π΅Π½Π΅ΡΠΈΡΡΡΡΠ΅Π³ΠΎ ΠΌΠΎΠ΄ΡΠ»Ρ, ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΉ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡΡ ΠΊΠΎΡΠΎΡΠΎΠ³ΠΎ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ΅ΠΏΠ»ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΡΠΉ Π±Π»ΠΎΠΊ, ΠΏΡΠ΅Π΄Π½Π°Π·Π½Π°ΡΠ΅Π½ Π΄Π»Ρ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ ΡΠ°Π±ΠΎΡΠ΅ΠΉ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ ΡΠΎΠ»Π½Π΅ΡΠ½ΡΡ
ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ². ΠΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΠ΅ ΠΈΡΠΏΡΡΠ°Π½ΠΈΡ ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΡΠ°ΠΊΠΈΡ
ΠΌΠΎΠ΄ΡΠ»Π΅ΠΉ, ΠΎΡΠ½Π°ΡΠ΅Π½Π½ΡΡ
ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΠΎΠΉ ΠΎΡ
Π»Π°ΠΆΠ΄Π΅Π½ΠΈΡ ΠΈ Π²ΡΡΠΎΠΊΠΎΠ²ΠΎΠ»ΡΡΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΠΎΠΉ ΠΎΡΠ±ΠΎΡΠ° ΠΌΠΎΡΠ½ΠΎΡΡΠΈ, Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΡΡΡ ΠΈΡ
Π½Π°Π΄Π΅ΠΆΠ½ΠΎΡΡΡ ΠΈ Π²ΡΡΠΎΠΊΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠΈΠ΅ Π΄ΠΎΡΡΠΈΡΡ ΠΠΠ Π³ΠΈΠ±ΡΠΈΠ΄Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ΄ΡΠ»Ρ Π΄ΠΎ 18,5 %
Π Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ Π΄ΠΈΡΡΠ°Π½ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ Π΄ΡΡ Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ Π°ΡΡΠΊΡΠ»ΡΡΠ°ΡΠΈΠΈ
Development of technical base, software, accumulated information on the diagnosis of the respiratory system provided the prerequisites for creating remote diagnostics of the human respiratory system through auscultation. The known methods do not solve the problem of determining auscultation points at patentΒ΄s housing without a diagnostic specialist. The purpose of this study is to develop a method for remote diagnostics of the respiratory system which provides ability to determine the points of auscultation without presence of a diagnostic specialist. The definition of auscultation points is provided using a computer program that allows to calculate the pointsΒ΄ coordinates based on the coordinates of points that determine the anatomical structure of the patient's torso. The patient or his assistant places the recording device at the auscultation points combining their images on the display with the image of the location of the recording device. The signal recorded at the auscultation point is remotely transmitted to a specialist for direct analysis and/or computer processing. The diagnostic module consists of two main units. The first unit contains a stethoscope, microphone, and amplifier connected to a mobile phone or other similar device containing an accelerometer. The patient or his assistant at the housing uses the unit. The second unit is a mobile phone with a mechanical marker or a computer with the ability to access the network in conjunction with the necessary software and is used remotely by a diagnostic specialist. The layout of the unit for recording and transmitting breath sounds was made. To avoid discrepancies in the diagnostic results the technical characteristics of the module elements must be normalized. Unified software is required for the module to function. The organizational tasks that need to be solved for the implementation of diagnostics are formulated. Use of the method of remote diagnostics of the respiratory system, providing the ability to determine points of auscultation without the direct presence of a diagnostic specialist and the module will allow increasing efficiency of treatment of pulmonary diseases reduce infection risks and economic costs
Intuition in business: Empirical base
In this article, the authors propose economic projection of the views of Daniel Kahneman on intuition. The authors believe intuition to act as an operative category in entrepreneurship. The results of given statistical experiment prove viability of the phenomenon of intuition when making investment decisions. Two independent mechanisms for investment decisions are being defined - the Β«rationalΒ» and the Β«intuitiveΒ» ones. The research leads to conclusion that entrepreneursβ intuitive decisions possess a relatively high level of efficiency. Β© 2016 Fomin et al
Improving the system of healthcare institution management in conditions of pandemic threats
The article is devoted to analysing activities of the infectious disease unit of a medical institution in one of Ukrainian regions. The unit is designed for intensive care of patients. The study main goal is to develop a strategy for further development of this unit to improve quality of its services and patient satisfaction. During the research, the initial conditions for the in-patient medical care provision were discussed. A comprehensive analysis of activities and structural problems within the infectious unit was carried out. Based on the study results, a strategic plan for further development was generated to enhance the unit efficiency and quality of its provided medical services. During analysing the infectious unit work, it was found that the in-patient care provision meets the worldwide infectious care norms. In the conditions of reforming the Ukrainian medical industry, many issues remain unresolved (in particular, restructuring and improvement of the healthcare system as a whole and that of the infectious disease unit). The latter plays an important role in creating a high-quality national program for medical service provision by healthcare institutions. Therefore, we succeed in improving resilience in the face of public health threats and risks. The analysis showed current positive trends in understanding the importance of this structural unit activities within the healthcare system. Besides, new ways of its modernisation are found. The authors substantiate this area development requires the national quality control indicators, the marketing policy improvement as well as the strengthened organisational and methodological role of the infectious disease service in healthcare institutions. Specific recommendations were formulated regarding ways to develop the infectious disease unit. They will help raise service satisfaction among patients of medical institutions. The obtained results are of practical importance and can be used in managing healthcare institutions at the national and regional levels
Dynamics of Π‘Π2 evolution bΡ plants at low pressure
Dynamics of Π‘Π2 evolut:ion at low pressure was studied in barley, maize, ΡΠ΅Π°, wheat and pine seedlings using the gas exchange system with laser photoacoust:ic spectrometer. The Π‘Π2 evolut:ion from plant surfaces to environment increased with decreasing air pressure. Simultaneously the changes in act:ivities of phosphoenolpyruvat
Formal methods of analysis and synthesis for decisions options during corporate information system development
The article presents a generalized approach to decision making in the process of application development based on cyclically repeating actions, including the synthesis of solution options and their analysis. They considered the basic methods of analysis and synthesis used in decision-making process on the design of corporate information systems (CIS). The description of the proposed generalized semantic model is given on
the example of component interaction of the Integrated complex of high-level development tools and the functioning environment of corporate-level information systems (Platform). They analyzed the process of CIS IT infrastructure on the basis of the Platform and the specific steps of making a management decision for this
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